Age-Related Decline in Primary CD8+ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8+ T Cells

Authors: Kylie M. Quinn, Annette Fox, Kim L. Harland, Brendan E. Russ, Jasmine Li, Thi H. O. Nguyen, Liyen Loh, Moshe Olshanksy, Haroon Naeem, Kirill Tsyganov, Florian Wiede, Rosela H. Webster, Chantelle Blyth, Xavier Y.X. Sng, Tony Tiganis, David Powell, Peter C. Doherty, Stephen J. Turner, Katherine Kedzierska, Nicole L. La Gruta - Cell Reports 2018 cited by 265

cells exhibit a profile consistent with senescence, marking an observation of senescence in an antigenically naive T cell population.