Enzyme-Linked Immunosorbent Assay for Quantitation of Human Antibodies to Pneumococcal Polysaccharides

Authors: Catherine M. Wernette, Carl E. Frasch, Dace V. Madore, George M. Carlone, David Goldblatt, Brian D. Plikaytis, William H. Benjamin, Sally A. Quataert, Steve Hildreth, Daniel J. Sikkema, Helena Käyhty, Ingileif Jónsdóttir, Moon H. Nahm - Clinical and Vaccine Immunology 2003 cited by 337

Streptococcus pneumoniae is a major human pathogen causing pneumonia, sepsis, meningitis, and otitis media ([12][1]). It causes infections most often in young children ([12][1]) and elderly adults ([1][2]) because their immune systems are either unprepared or unable to respond effectively to