Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

Authors: Balaji Virassamy, Franco Caramia, Peter Savas, Sneha Sant, Jianan Wang, Susan N. Christo, Ann Byrne, Kylie Clarke, Emmaline Brown, Zhi L. Teo, Bianca von Scheidt, David Freestone, Luke C. Gandolfo, Karsten E. Weber, Julia Teply‐Szymanski, Ran Li, Stephen J. Luen, Carsten Denkert, Sibylle Loibl, Olivia Lucas, Charles Swanton, Terence P. Speed, Phillip K. Darcy, Paul J. Neeson, Laura K. Mackay, Sherene Loi - Cancer Cell 2023 cited by 221

gene signature extracted from tumor-free tissue was significantly associated with improved clinical outcomes in TNBC patients treated with checkpoint inhibitors.