LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade

Authors: Ronglai Shen, Michael A. Postow, Matthew Adamow, Arshi Arora, Margaret Hannum, Colleen Maher, Phillip Wong, Michael A. Curran, Travis J. Hollmann, Liwei Jia, Hikmat Al‐Ahmadie, Niamh M. Keegan, Samuel A. Funt, Gopa Iyer, Jonathan E. Rosenberg, Dean F. Bajorin, Paul B. Chapman, Alexander N. Shoushtari, Allison Betof Warner, Parisa Momtaz, Taha Merghoub, Jedd D. Wolchok, Katherine S. Panageas, Margaret K. Callahan - Science Translational Medicine 2021 cited by 98

immunotype detects patients who are less likely to benefit from ICB and suggests a strategy for identifying actionable immune targets for further investigation.