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Acidic Microenvironment Up-Regulates Exosomal miR-21 and miR-10b in Early-Stage Hepatocellular Carcinoma to Promote Cancer Cell Proliferation and Metastasis

Authors: Xiao-Peng Tian, Chen-Yuan Wang, Xiao-Han Jin, Mei Li, Feng-Wei Wang, Wei-Juan Huang, Jing‐Ping Yun, Rui‐Hua Xu, Qing-Qing Cai, Dan Xie - Theranostics 2019 cited by 258

Our findings suggested that the exosomal miR-21 and miR-10b induced by acidic microenvironment in HCC promote cancer cell proliferation and metastasis and may serve as prognostic molecular markers and therapeutic targets for HCC.

Acidic Microenvironment Up-Regulates Exosomal miR-21 and miR-10b in Early-Stage Hepatocellular Carcinoma to Promote Cancer Cell Proliferation and Metastasis | Litlas