Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters

Authors: Lulu Sun, Yuanyuan Pang, Xuemei Wang, Qing Wu, Huiying Liu, Bo Liu, Chaojie Liu, Min Ye, Wei Xi Kong, Changtao Jiang - Acta Pharmaceutica Sinica B 2019 cited by 199

MCA). The intestinal FXR signaling was suppressed but remained unchanged in the liver. This study is of potential translational significance in determining the role of gut microbiota-mediated bile acid metabolism in modulating diet-induced glucose intolerance and hepatic steatosis in the hamster.