Integrated microbiome and metabolome analysis reveals a novel interplay between commensal bacteria and metabolites in colorectal cancer

Authors: Yongzhi Yang, Biswapriya B. Misra, Lei Liang, Dexi Bi, Wenhao Weng, Wen Wu, Sanjun Cai, Huanlong Qin, Ajay Goel, Xinxiang Li, Yanlei Ma - Theranostics 2019 cited by 313

: Our results provide substantial evidence of a novel interplay between the gut microbiome and metabolome (i.e., polyamines), which is drastically perturbed in CRC. Microbe-associated metabolites can be used as diagnostic biomarkers in therapeutic explorations.