Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularization

Authors: Xuemei Zong, Yuyu Li, Cui Liu, Wenxuan Qi, Dong Han, Lorelei Tucker, Yan Dong, Shuqun Hu, Xianliang Yan, Quanguang Zhang - Theranostics 2020 cited by 138

These results indicate that rTMS can exert powerful protective and restorative effects on the peri-infarct microvasculature after PT stroke by, in part, promoting HIF-1α signaling and shifting vessel-associated astrocytic polarization to the A2 phenotype. This study provides further support for the potent protective effects of rTMS in the context of ischemic stroke, and these findings implicate vascular repair and protection as an important underlying phenomenon.