Engineered Bacteriophages Containing Anti-CRISPR Suppress Infection of Antibiotic-Resistant P. aeruginosa

Authors: Shugang Qin, Yongan Liu, Yuting Chen, Jinrong Hu, Wen Xiao, Xiaoshan Tang, Guohong Li, Ping Lin, Qinqin Pu, Qun Wu, Chuan‐Min Zhou, Biao Wang, Pan Gao, Zhihan Wang, Aixin Yan, Khan Nadeem, Zhenwei Xia, Min Wu - Microbiology Spectrum 2022 cited by 46

. EATPs also significantly suppressed the antibiotic resistance caused by a highly antibiotic-resistant PA14 infection, which may provide novel insight toward developing bacteriophages to treat patients with intractable bacterial infections, especially infections by clinically MDR bacteria that are unresponsive to conventional antibiotic therapy.