The HDAC10 instructs macrophage M2 program via deacetylation of STAT3 and promotes allergic airway inflammation

Authors: Yu Zhong, Tong Huang, Jiewen Huang, Jieru Quan, Guomei Su, Zhilin Xiong, Yingying Lv, Shihai Li, Xianwen Lai, Yuanyuan Xiang, Qu Wang, Lianxiang Luo, Xiao Gao, Yi Ming Shao, Jing Tang, Tianwen Lai - Theranostics 2023 cited by 80

Our results revealed that HDAC10-STAT3 interaction governs macrophage polarization to promote airway inflammation in asthma, implicating HDAC10 as a therapeutic target.