The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

Authors: Patrick S. Ward, Jay Patel, David R. Wise, Omar Abdel‐Wahab, Bryson D. Bennett, Hilary A. Coller, Justin R. Cross, Valeria R. Fantin, Cyrus V. Hedvat, Alexander E. Perl, Joshua D. Rabinowitz, Martin Carroll, Shinsan M. Su, Kim A. Sharp, Ross L. Levine, Craig B. Thompson - Cancer Cell 2010 cited by 1,986