Christopher W. Murray
1988–2024 年に発表
- 83
- 論文数
- 19,107
- 被引用数
- 59
- h 指数
- 80
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Computer Science44.3%
- Biochemistry, Genetics and Molecular Biology27%
- Medicine15.2%
- Chemistry4.7%
- Materials Science2%
- Physics and Astronomy1.5%
- その他5.3%
トピック
- Computational Drug Discovery Methods20%
- Protein Structure and Dynamics9.1%
- Chemical Synthesis and Analysis3.3%
- Click Chemistry and Applications2.9%
- Enzyme Structure and Function2.6%
- Microbial Natural Products and Biosynthesis2.3%
- その他59.8%
共著者
- David C. Rees15
- Marcel L. Verdonk15
- Gianni Chessari12
- Miles Congreve12
- David E. Clark11
- Monte M. Winslow10
- Michael J. Hartshorn9
- Richard J. Hall9
- Harren Jhoti8
- Anne Cleasby7
- David R. Westhead7
- Marc O’Reilly7
- Martyn Frederickson7
- Min K. Tsai7
- Robin A. E. Carr7
- Bohdan Waszkowycz6
- Hongchen Cai6
- Jin Li6
- Paul N. Mortenson6
- Richard D. Taylor6
- Sahil Patel6
- Chuan Li5
- Dmitri A. Petrov5
- Joseph E. Coyle5
全論文
- Improved protein–ligand docking using GOLD
著者: Marcel L. Verdonk, Jason C. Cole, Michael J. Hartshorn, Christopher W. Murray, Richard D. Taylor - Proteins Structure Function and Bioinformatics 2003 被引用: 3,042
- A ‘Rule of Three’ for fragment-based lead discovery?
著者: Miles Congreve, Robin A. E. Carr, Christopher W. Murray, Harren Jhoti - Drug Discovery Today 2003 被引用: 1,355
- The rise of fragment-based drug discovery
著者: Christopher W. Murray, David C. Rees - Nature Chemistry 2009 被引用: 794
- Diverse, High-Quality Test Set for the Validation of Protein−Ligand Docking Performance
著者: Michael J. Hartshorn, Marcel L. Verdonk, Gianni Chessari, Suzanne Brewerton, Wijnand T. M. Mooij, Paul N. Mortenson, Christopher W. Murray - Journal of Medicinal Chemistry 2007 被引用: 642
- Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor
著者: Timothy Perera, Eleonora Jovcheva, Laurence Mévellec, Jorge Vialard, Desiree De Lange, Tinne Verhulst, Caroline Paulussen, Kelly Van De Ven, Peter King, Eddy Freyne, David C. Rees, Matthew Squires, Gordon Saxty, Martin Pagé, Christopher W. Murray, Ron Gilissen, George A. Ward, Neil T. Thompson, David R. Newell, Na Cheng, Liang Xie, Jennifer Yang, Suso Platero, Jayaprakash D. Karkera, Christopher Moy, Patrick Angibaud, Sylvie Laquerre, Matthew V. Lorenzi - Molecular Cancer Therapeutics 2017 被引用: 340
- Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes
著者: Matthew D. Eldridge, Christopher W. Murray, Timothy R. Auton, Gaia Valeria Paolini, Roger P. Mee - Journal of Computer-Aided Molecular Design, J. Comput. Aided Mol. Des. 1997 被引用: 1,681
- The 'rule of three' for fragment-based drug discovery: where are we now?
著者: Harren Jhoti, Glyn Williams, David C. Rees, Christopher W. Murray - Nature Reviews Drug Discovery 2013 被引用: 325
- Fragment-based lead discovery
著者: David C. Rees, Miles Congreve, Christopher W. Murray, Robin A. E. Carr - Nature Reviews Drug Discovery 2004 被引用: 796
- The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D
著者: Andrea C. Chaikovsky, Chuan Li, Edwin E. Jeng, Samuel Loebell, Myung Chang Lee, Christopher W. Murray, Ran Cheng, János Demeter, Danielle L. Swaney, Sihan Chen, Billy W. Newton, Jeffrey R. Johnson, Alexandros P. Drainas, Yan Ting Shue, José A. Seoane, Preethi Srinivasan, Andy He, Akihiro Yoshida, Susan Q. Hipkins, Edel M. McCrea, Carson D. Poltorack, Nevan J. Krogan, J. Alan Diehl, Christina S. Kong, Peter K. Jackson, Christina Curtis, Dmitri A. Petrov, Michael C. Bassik, Monte M. Winslow, Julien Sage - Nature 2021 被引用: 167
- Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages
著者: Michael Gonzalez, Daniel Lu, Maryam Yousefi, Ashley V. Kroll, Chen Hao Lo, Carlos G. Briseño, J. E. Vivienne Watson, Sergey V. Novitskiy, Vanessa Arias, Hong Zhou, Andres Plata Stapper, Min K. Tsai, Emily L. Ashkin, Christopher W. Murray, Chi-Ming Li, Monte M. Winslow, Kristin V. Tarbell - The Journal of Experimental Medicine 2023 被引用: 62
- Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia
著者: György M. Keserű, Daniel A. Erlanson, György G. Ferenczy, Michael M. Hann, Christopher W. Murray, Stephen D. Pickett - Journal of Medicinal Chemistry 2016 被引用: 233
- Fragment-Based Lead Discovery Using X-ray Crystallography
著者: Michael J. Hartshorn, Christopher W. Murray, Anne Cleasby, Martyn Frederickson, Ian J. Tickle, Harren Jhoti - Journal of Medicinal Chemistry 2004 被引用: 423
- Modeling Water Molecules in Protein−Ligand Docking Using GOLD
著者: Marcel L. Verdonk, Gianni Chessari, Jason C. Cole, Michael J. Hartshorn, Christopher W. Murray, J. Willem M. Nissink, Richard D. Taylor, Robin Taylor - Journal of Medicinal Chemistry 2005 被引用: 390
- An LKB1–SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation
著者: Christopher W. Murray, Jennifer J. Brady, Min K. Tsai, Chuan Li, Ian P. Winters, Rui Tang, Laura Andrejka, K. Rosanna, Christian A. Kunder, Pauline Chu, Monte M. Winslow - Cancer Discovery 2019 被引用: 112
- Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design
著者: Andrew Woodhead, Hayley C. Angove, Maria G. Carr, Gianni Chessari, Miles Congreve, Joseph E. Coyle, José Cosme, Brent Graham, Philip J. Day, Robert Downham, Lynsey Fazal, Ruth E. Feltell, Eva Figueroa, Martyn Frederickson, Jonathan J. Lewis, Rachel McMenamin, Christopher W. Murray, Alistair O’Brien, Lina M. Parra, Sahil Patel, Theresa R. Phillips, David C. Rees, Sharna J. Rich, Donna-Michelle Smith, Gary Trewartha, M. Vinković, Brian Williams, Alison J.‐A. Woolford - Journal of Medicinal Chemistry 2010 被引用: 263
- A successful collaboration between academia, biotech and pharma led to discovery of erdafitinib, a selective FGFR inhibitor recently approved by the FDA
著者: Christopher W. Murray, David R. Newell, Patrick Angibaud - MedChemComm 2019 被引用: 79
- Comparing protein–ligand docking programs is difficult
著者: Jason C. Cole, Christopher W. Murray, J. Willem M. Nissink, Richard D. Taylor, Richard D. Taylor, Robin Taylor, Robin Taylor - Proteins Structure Function and Bioinformatics 2005 被引用: 365
- Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design
著者: Marc O’Reilly, Anne Cleasby, Thomas G. Davies, Richard J. Hall, R. Frederick Ludlow, Christopher W. Murray, Dominic Tisi, Harren Jhoti - Drug Discovery Today 2019 被引用: 97
- Fragment-based drug discovery: opportunities for organic synthesis
著者: Jeffrey D. St. Denis, Richard J. Hall, Christopher W. Murray, Tom D. Heightman, David C. Rees - RSC Medicinal Chemistry 2020 被引用: 73
- A versatile system to record cell-cell interactions
著者: Rui Tang, Christopher W. Murray, Ian L. Linde, Nicholas J. Kramer, Zhonglin Lyu, Min K. Tsai, Leo C. Chen, Hongchen Cai, Aaron D. Gitler, Edgar G. Engleman, Wonjae Lee, Monte M. Winslow - eLife 2020 被引用: 49
- Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth
著者: Rui Tang, Emily G. Shuldiner, Marcus R. Kelly, Christopher W. Murray, Jess D. Hebert, Laura Andrejka, Min K. Tsai, Nicholas W. Hughes, Mitchell I. Parker, Hongchen Cai, Yaocheng Li, Geoffrey M. Wahl, Roland L. Dunbrack, Peter K. Jackson, Dmitri A. Petrov, Monte M. Winslow - Nature Cell Biology 2023 被引用: 33
- Efficient exploration of chemical space by fragment-based screening
著者: Richard J. Hall, Paul N. Mortenson, Christopher W. Murray - Progress in Biophysics and Molecular Biology 2014 被引用: 164
- Validity of Ligand Efficiency Metrics
著者: Christopher W. Murray, Daniel A. Erlanson, Andrew L. Hopkins, György M. Keserű, Paul D. Leeson, David C. Rees, Charles H. Reynolds, Nicola J. Richmond - ACS Medicinal Chemistry Letters 2014 被引用: 135
- Docking Performance of Fragments and Druglike Compounds
著者: Marcel L. Verdonk, Ilenia Giangreco, Richard J. Hall, Oliver Korb, Paul N. Mortenson, Christopher W. Murray - Journal of Medicinal Chemistry 2011 被引用: 127
