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David D. Schlaepfer

1987–2025 年に発表

92
論文数
26,951
被引用数
79
h 指数
90
i10 指数

被引用数

David D. Schlaepfer の年別被引用数1959 年: 被引用 1 件1979 年: 被引用 1 件1981 年: 被引用 2 件1987 年: 被引用 5 件1988 年: 被引用 32 件1989 年: 被引用 30 件1990 年: 被引用 39 件1991 年: 被引用 33 件1992 年: 被引用 32 件1993 年: 被引用 30 件1994 年: 被引用 24 件1995 年: 被引用 63 件1996 年: 被引用 101 件1997 年: 被引用 109 件1998 年: 被引用 152 件1999 年: 被引用 232 件2000 年: 被引用 273 件2001 年: 被引用 346 件2002 年: 被引用 348 件2003 年: 被引用 384 件2004 年: 被引用 401 件2005 年: 被引用 353 件2006 年: 被引用 349 件2007 年: 被引用 263 件2008 年: 被引用 306 件2009 年: 被引用 381 件2010 年: 被引用 336 件2011 年: 被引用 296 件2012 年: 被引用 251 件2013 年: 被引用 201 件2014 年: 被引用 283 件2015 年: 被引用 166 件2016 年: 被引用 189 件2017 年: 被引用 233 件2018 年: 被引用 151 件2019 年: 被引用 681 件2020 年: 被引用 663 件2021 年: 被引用 657 件2022 年: 被引用 510 件2023 年: 被引用 376 件2024 年: 被引用 604 件2025 年: 被引用 248 件2026 年: 被引用 7 件1960〜1978 年は被引用が無いため表示していません1980 年は被引用が無いため表示していません1982〜1986 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 3,118 件、この内訳の 36.2%中国: 引用元論文 1,002 件、この内訳の 11.6%イギリス: 引用元論文 570 件、この内訳の 6.6%ドイツ: 引用元論文 478 件、この内訳の 5.5%日本: 引用元論文 342 件、この内訳の 4%イタリア: 引用元論文 295 件、この内訳の 3.4%フランス: 引用元論文 291 件、この内訳の 3.4%カナダ: 引用元論文 283 件、この内訳の 3.3%スペイン: 引用元論文 165 件、この内訳の 1.9%韓国: 引用元論文 161 件、この内訳の 1.9%オランダ: 引用元論文 161 件、この内訳の 1.9%オーストラリア: 引用元論文 155 件、この内訳の 1.8%
0%36.2%その他 18.5%

機関

分野

  • Medicine45.3%
  • Biochemistry, Genetics and Molecular Biology43.7%
  • Immunology and Microbiology3.6%
  • Neuroscience3%
  • Engineering1.6%
  • Materials Science0.8%
  • その他2%

トピック

  • Cell Adhesion Molecules Research12.3%
  • Cellular Mechanics and Interactions9.2%
  • Cancer Cells and Metastasis2.6%
  • Protein Kinase Regulation and GTPase Signaling2.3%
  • Protease and Inhibitor Mechanisms2.1%
  • Angiogenesis and VEGF in Cancer2.1%
  • その他69.4%

共著者

全論文

検索で開く
  1. Targeting FAK in anticancer combination therapies

    著者: John C. Dawson, Alan Serrels, Dwayne G. Stupack, David D. Schlaepfer, Margaret C. Frame - Nature reviews. Cancer 2021 被引用: 391

  2. FAK in cancer: mechanistic findings and clinical applications

    著者: Florian J. Sulzmaier, Christine Jean, David D. Schlaepfer - Nature reviews. Cancer 2014 被引用: 1,394

  3. Integrin-regulated FAK–Src signaling in normal and cancer cells

    著者: Satyajit K. Mitra, David D. Schlaepfer - Current Opinion in Cell Biology 2006 被引用: 1,583

  4. Focal adhesion kinase: in command and control of cell motility

    著者: Satyajit K. Mitra, Daniel Hanson, David D. Schlaepfer - Nature Reviews Molecular Cell Biology 2005 被引用: 2,547

  5. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

    著者: Hanane Laklai, Yekaterina A. Miroshnikova, Michael W. Pickup, Eric A. Collisson, Grace Kim, Alex Barrett, Ryan C. Hill, Johnathon N. Lakins, David D. Schlaepfer, Janna K. Mouw, Valerie S. LeBleu, Nilotpal Roy, Sergey V. Novitskiy, Julia S. Johansen, Valeria Poli, Raghu Kalluri, Christine A. Iacobuzio–Donahue, Laura D. Wood, Matthias Hebrok, Kirk C. Hansen, Harold L. Moses, Valerie M. Weaver - Nature Medicine 2016 被引用: 601

  6. A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK

    著者: Xiaodong Feng, Nadia Arang, Damiano Cosimo Rigiracciolo, Joo Sang Lee, Huwate Yeerna, Zhiyong Wang, Simone Lubrano, Ayush Kishore, Jonathan A. Pachter, Gabriele M. König, Marcello Maggiolini, Evi Kostenis, David D. Schlaepfer, Pablo Tamayo, Qianming Chen, Eytan Ruppin, J. Silvio Gutkind - Cancer Cell 2019 被引用: 243

  7. Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

    著者: Ana M. Pasapera, I Schneider, Erin Rericha, David D. Schlaepfer, Clare M. Waterman - The Journal of Cell Biology 2010 被引用: 577

  8. Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis

    著者: Duygu Ozmadenci, Jayanth S. Shankara Narayanan, Jacob R. Andrew, Marjaana Ojalill, A. Barrie, Shulin Jiang, Samhita Iyer, Xiao Lei Chen, Michael Rose, Valeria Estrada, Alfredo Molinolo, Thomas Bertotto, Zbigniew Mikulski, Michael C. McHale, Rebekah R. White, Denise C. Connolly, Jonathan A. Pachter, Vijay K. Kuchroo, Dwayne G. Stupack, David D. Schlaepfer - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 被引用: 75

  9. Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation

    著者: Ssang‐Taek Lim, Xiao Lei Chen, Yangmi Lim, Dan Hanson, Thanh‐Trang Vo, Kyle Howerton, Nicholas Larocque, Susan J. Fisher, David D. Schlaepfer, Duško Ilić - Molecular Cell 2008 被引用: 474

  10. FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer

    著者: Sonia Zaghdoudi, Emilie Decaup, Ismahane Belhabib, Rémi Samain, Stéphanie Cassant‐Sourdy, Julia Rochotte, Alexia Brunel, David D. Schlaepfer, Jérôme Cros, Cindy Neuzillet, Manon Strehaïano, Amandine Alard, Richard Tomasini, Vinothini Rajeeve, Aurélie Perraud, Muriel Mathonnet, Oliver M.T. Pearce, Yvan Martineau, Stéphane Pyronnet, Corinne Bousquet, Christine Jean - EMBO Molecular Medicine 2020 被引用: 105

  11. Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

    著者: Dennis W. Zhou, Marc Fernández, Elijah N. Holland, Andrés F. García, Nicolas Castro, Eric B. O’Neill, Jeroen Eyckmans, Christopher S. Chen, Jianping Fu, David D. Schlaepfer, Andrés J. Garcı́a - Nature Communications 2021 被引用: 84

  12. FAK integrates growth-factor and integrin signals to promote cell migration

    著者: David J. Sieg, Christof R. Hauck, Duško Ilić, Candice K. Klingbeil, Erik Schaefer, Caroline H. Damsky, David D. Schlaepfer - Nature Cell Biology 2000 被引用: 1,239

  13. Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function

    著者: Christine Jean, Xiao Lei Chen, Ju‐Ock Nam, Isabelle Tancioni, Sean Uryu, Christine Lawson, Kristy Ward, Colin Walsh, Nichol Miller, Majid Ghassemian, Patric Turowski, Elisabetta Dejana, Sara M. Weis, David A. Cheresh, David D. Schlaepfer - The Journal of Cell Biology 2014 被引用: 172

  14. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

    著者: David D. Schlaepfer, Steven K. Hanks, Tony Hunter, Peter van der Geer - Nature 1994 被引用: 1,610

  15. VEGF-Induced Vascular Permeability Is Mediated by FAK

    著者: Xiao Lei Chen, Ju‐Ock Nam, Christine Jean, Christine Lawson, Colin Walsh, Erik T. Goka, Ssang‐Taek Lim, Alok Tomar, Isabelle Tancioni, Sean Uryu, Jun‐Lin Guan, Lisette M. Acevedo, Sara M. Weis, David A. Cheresh, David D. Schlaepfer - Developmental Cell 2012 被引用: 338

  16. FAK Activation Promotes SMC Dedifferentiation via Increased DNA Methylation in Contractile Genes

    著者: Kyuho Jeong, James M. Murphy, Jung-Hyun Kim, Pamela Moore Campbell, Hyeonsoo Park, Yelitza A.R. Rodriguez, Chung-Sik Choi, Jun-Sub Kim, Sangwon Park, Hyun Joon Kim, Jonathan G. Scammell, David S. Weber, Richard E. Honkanen, David D. Schlaepfer, Eun-Young Erin Ahn, Ssang-Taek Steve Lim - Circulation Research 2021 被引用: 42

  17. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

    著者: Isabelle Tanjoni, Colin Walsh, Sean Uryu, Alok Tomar, Ju‐Ock Nam, Ainhoa Mielgo, Ssang‐Taek Lim, Congxin Liang, Marcel Koenig, Neela Patel, Cheni Kwok, Gerald McMahon, Dwayne G. Stupack, David D. Schlaepfer - Cancer Biology & Therapy 2010 被引用: 162

  18. Nuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 Transcription

    著者: Kyuho Jeong, Jung‐Hyun Kim, James M. Murphy, Hyeon‐Soo Park, Su-Jeong Kim, Yelitza A. R. Rodriguez, Hyunkyung Kong, Chung‐Sik Choi, Jun‐Lin Guan, Joan M. Taylor, Thomas Lincoln, William T. Gerthoffer, Jun‐Sub Kim, E. Ahn, David D. Schlaepfer, Ssang‐Taek Lim, David D. Schlaepfer, Ssang‐Taek Lim - Circulation Research 2019 被引用: 135

  19. Differential regulation of cell motility and invasion by FAK

    著者: Datsun A. Hsia, Satyajit K. Mitra, Christof R. Hauck, Daniel N. Streblow, Jay A. Nelson, Duško Ilić, Shuang Huang, Erguang Li, Glen R. Nemerow, Jay Leng, Kathryn Spencer, David A. Cheresh, David D. Schlaepfer - The Journal of Cell Biology 2003 被引用: 530

  20. FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β

    著者: Chenxi Gao, Guangming Chen, Shih–Fan Kuan, Dennis Han Zhang, David D. Schlaepfer, Jing Hu - eLife 2015 被引用: 120

  21. Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression

    著者: Kristy Ward, Isabelle Tancioni, Christine Lawson, Nichol Miller, Christine Jean, Xiao Lei Chen, Sean Uryu, Josephine Kim, David G. Jackson, Dwayne G. Stupack, Steven C. Plaxe, David D. Schlaepfer - Clinical & Experimental Metastasis 2012 被引用: 111

  22. FAK, vinculin, and talin control mechanosensitive YAP nuclear localization

    著者: Elijah N. Holland, Marc Fernández, Dennis W. Zhou, Eric B. O’Neill, Ayanna U. Woodfolk, Ana Mora‐Boza, Jianping Fu, David D. Schlaepfer, Andrés J. Garcı́a - Biomaterials 2024 被引用: 51

  23. Signaling through focal adhesion kinase

    著者: David D. Schlaepfer, Christof R. Hauck, David J. Sieg - Progress in Biophysics and Molecular Biology 1999 被引用: 1,171

  24. Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility

    著者: Alok Tomar, David D. Schlaepfer - Current Opinion in Cell Biology 2009 被引用: 234