David Stokoe
1992–2025 年に発表
- 60
- 論文数
- 22,674
- 被引用数
- 55
- h 指数
- 57
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology62.2%
- Medicine29.5%
- Immunology and Microbiology3.6%
- Neuroscience1.5%
- Computer Science1.1%
- Chemistry0.6%
- その他1.5%
トピック
- PI3K/AKT/mTOR signaling in cancer7%
- Protein Kinase Regulation and GTPase Signaling5.7%
- Melanoma and MAPK Pathways4%
- Cancer, Hypoxia, and Metabolism2.5%
- Cancer Immunotherapy and Biomarkers2.4%
- Glioma Diagnosis and Treatment2.3%
- その他76.1%
共著者
- Daphne A. Haas-Kogan14
- Frank McCormick8
- Mitchel S. Berger6
- Peter M. Haverty6
- Howard M. Stern5
- Kathleen R. Lamborn5
- Kevan M. Shokat5
- Somasekar Seshagiri5
- Zachary A. Knight5
- Alexander Gottschalk4
- Christiaan Klijn4
- Florian Gnad4
- Frédéric J. de Sauvage4
- James Lee4
- Michael D. Prados4
- Thomas D. Wu4
- William A. Weiss4
- Gordon B. Mills3
- Jeffrey Settleman3
- Jeremy Stinson3
- Michelle Wong3
- Nicholas M. Dean3
- Phillip T. Hawkins3
- Richard Bourgon3
全論文
- Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
著者: Andrew T. Parsa, James S. Waldron, Amith Panner, Courtney A. Crane, Ian F. Parney, Jeffrey J. Barry, Kristine E. Cachola, Joseph C. Murray, Tarık Tihan, Michael C. Jensen, Paul S. Mischel, David Stokoe, Russell O. Pieper - Nature Medicine 2006 被引用: 1,350
- RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
著者: Georgia Hatzivassiliou, Kyung Song, Ivana Yen, Barbara J. Brandhuber, Daniel J. Anderson, Ryan Alvarado, Mary J. C. Ludlam, David Stokoe, Susan L. Gloor, Guy Vigers, Tony Morales, Ignacio Aliagas, Bonnie Liu, Steve Sideris, Klaus P. Hoeflich, Bijay S. Jaiswal, Somasekar Seshagiri, Hartmut Koeppen, Marcia Belvin, Lori S. Friedman, Shiva Malek - Nature 2010 被引用: 1,638
- A comprehensive transcriptional portrait of human cancer cell lines
著者: Christiaan Klijn, Steffen Durinck, Eric Stawiski, Peter M. Haverty, Zhaoshi Jiang, Hanbin Liu, Jeremiah D. Degenhardt, Oleg Mayba, Florian Gnad, Jinfeng Liu, Grégoire Pau, Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh Selvaraj, Mamie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrušan, Richard M. Neve, Frédéric J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Zemin Zhang - Nature Biotechnology 2014 被引用: 724
- Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
著者: Till Maurer, Lindsay S. Garrenton, Angela Oh, Keith Pitts, Daniel J. Anderson, Nicholas J. Skelton, Benjamin P. Fauber, Borlan Pan, Shiva Malek, David Stokoe, Mary J. C. Ludlam, Krista K. Bowman, Jiansheng Wu, Anthony M. Giannetti, Melissa A. Starovasnik, Ira Mellman, Peter K. Jackson, Joachim Rudolph, Weiru Wang, Guowei Fang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 被引用: 630
- A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling
著者: Zachary A. Knight, Beatriz González, Morri E. Feldman, Eli R. Zunder, David Goldenberg, Olusegun Williams, Robbie Loewith, David Stokoe, András Balla, Balázs István Tóth, Tamás Balla, William A. Weiss, Roger Williams, Kevan M. Shokat - Cell 2006 被引用: 1,154
- Diverse somatic mutation patterns and pathway alterations in human cancers
著者: Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson, Vasantharajan Janakiraman, Deepali Bhatt, Howard M. Stern, Peng Yue, Peter M. Haverty, Richard Bourgon, Jianbiao Zheng, Martin Moorhead, Subhra Chaudhuri, Lynn P. Tomsho, Brock A. Peters, Kanan Pujara, Shaun Cordes, David P. Davis, Victoria Carlton, Wenlin Yuan, Li Li, Weiru Wang, Charles Eigenbrot, Joshua S. Kaminker, David A. Eberhard, Paul Waring, Stephan C. Schuster, Zora Modrušan, Zemin Zhang, David Stokoe, Frédéric J. de Sauvage, Malek Faham, Somasekar Seshagiri - Nature 2010 被引用: 1,034
- Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B
著者: David Stokoe, Leonard R. Stephens, Terry Copeland, Piers R. J. Gaffney, Colin B. Reese, Gavin F. Painter, Andrew B. Holmes, Frank McCormick, Phillip T. Hawkins - Science 1997 被引用: 1,213
- Structure of the p53 degradation complex from HPV16
著者: John Wang, Hannah T. Baddock, Amirhossein Mafi, Ian T. Foe, Matthew Bratkowski, Ting‐Yu Lin, Zena D. Jensvold, Magdalena Preciado López, David Stokoe, Dan Eaton, Qi Hao, Aaron H. Nile - Nature Communications 2024 被引用: 57
- Loss of PTEN facilitates HIF-1-mediated gene expression
著者: Wayne Zundel, Cornelia Schindler, Daphne A. Haas‐Kogan, Albert C. Koong, Fiona Kaper, Eunice Y. Chen, Alexander Gottschalk, Heather E. Ryan, Randall S. Johnson, Anne B. Jefferson, David Stokoe, Amato J. Giaccia - Genes & Development 2000 被引用: 833
- Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers
著者: Leonard D. Goldstein, James Lee, Florian Gnad, Christiaan Klijn, Annalisa Schaub, Jens Reeder, Anneleen Daemen, Corey E. Bakalarski, Thomas Holcomb, David S. Shames, Ryan J. Hartmaier, Juliann Chmielecki, Somasekar Seshagiri, Robert Gentleman, David Stokoe - Cell Reports 2016 被引用: 211
- KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer
著者: Michael R. Burgess, Eugene Hwang, Rana Mroue, Craig M. Bielski, Anica M. Wandler, Benjamin J. Huang, Ari J. Firestone, Amy Young, Jennifer A. Lacap, Lisa Crocker, Saurabh Asthana, Elizabeth M. Davis, Jin Xu, Keiko Akagi, Michelle M. Le Beau, Qing Li, Benjamin Haley, David Stokoe, Deepak Sampath, Barry S. Taylor, Marie Evangelista, Kevin Shannon - Cell 2017 被引用: 188
- Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors
著者: Ingo K. Mellinghoff, Maria Y. Wang, Igor Vivanco, Daphne A. Haas‐Kogan, Shaojun Zhu, Ederlyn Q. Dia, Kan Lu, Koji Yoshimoto, Julie H. Huang, Dennis J. Chute, Bridget L. Riggs, Steve Horvath, Linda M. Liau, Webster K. Cavenee, P. Nagesh Rao, Rameen Beroukhim, Timothy C. Peck, Jeffrey C. Lee, William R. Sellers, David Stokoe, Michael D. Prados, Timothy F. Cloughesy, Charles L. Sawyers, Paul S. Mischel - New England Journal of Medicine 2005 被引用: 1,448
- Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B
著者: Len Stephens, Karen E. Anderson, David Stokoe, Hediye Erdjument‐Bromage, Gavin F. Painter, Andrew B. Holmes, Piers R. J. Gaffney, Colin B. Reese, Frank McCormick, Paul Tempst, John Coadwell, Phillip T. Hawkins - Science 1998 被引用: 1,063
- Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
著者: Genee Y. Lee, Peter M. Haverty, Li Li, Noelyn M. Kljavin, Richard Bourgon, James Lee, Howard M. Stern, Zora Modrušan, Somasekar Seshagiri, Zemin Zhang, David Davis, David Stokoe, Jeffrey Settleman, Frédéric J. de Sauvage, Richard M. Neve - Cancer Research 2014 被引用: 163
- Activation of Raf as a Result of Recruitment to the Plasma Membrane
著者: David Stokoe, Susan G. Macdonald, Karen A. Cadwallader, Marc Symons, John F. Hancock - Science 1994 被引用: 987
- Induction of NF-κB by the Akt/PKB kinase
著者: Larry Kane, Virginia Smith Shapiro, David Stokoe, Arthur Weiss - Current Biology 1999 被引用: 854
- Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
著者: Michael D. Prados, Susan M. Chang, Nicholas Butowski, Rebecca DeBoer, Rupa Parvataneni, Hannah Carliner, Paul Kabuubi, Jennifer Ayers-Ringler, Jane Rabbitt, Margaretta Page, Anne Fedoroff, Penny K. Sneed, Mitchel S. Berger, Michael W. McDermott, Andrew T. Parsa, Scott R. VandenBerg, C. David James, Kathleen R. Lamborn, David Stokoe, Daphne A. Haas‐Kogan - Journal of Clinical Oncology 2008 被引用: 376
- Akt activation by growth factors is a multiple-step process: the role of the PH domain
著者: Alfonso Bellacosa, Tung O. Chan, Naheed N. Ahmed, Ketaki Datta, Scott Malstrom, David Stokoe, Frank McCormick, Jinan Feng, Philip N. Tsichlis - Oncogene 1998 被引用: 542
- A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma
著者: Qi-Wen Fan, Zachary A. Knight, David Goldenberg, Wei Yu, Keith E. Mostov, David Stokoe, Kevan M. Shokat, William A. Weiss - Cancer Cell 2006 被引用: 584
- Disruption of PH–kinase domain interactions leads to oncogenic activation of AKT in human cancers
著者: Chaitali Parikh, Vasantharajan Janakiraman, Wen‐I Wu, Catherine K. Foo, Noelyn M. Kljavin, Subhra Chaudhuri, Eric Stawiski, Brian Lee, Jie Lin, Hong Li, Maria Lorenzo, Wenlin Yuan, Joseph Guillory, Marlena Jackson, Jesus Rondon, Yvonne Franke, Krista K. Bowman, Meredith Sagolla, Jeremy Stinson, Thomas D. Wu, Jiansheng Wu, David Stokoe, Howard M. Stern, Barbara J. Brandhuber, Kui Lin, Nicholas J. Skelton, Somasekar Seshagiri - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 被引用: 150
- Sp1 Is Involved in Akt-mediated Induction of VEGF Expression through an HIF-1–independent Mechanism
著者: Nabendu Pore, Shuang Liu, Hui‐Kuo G. Shu, Bin Li, Daphne A. Haas-Kogan, David Stokoe, Julie Milanini, Gilles Pagès, Donald M. O’Rourke, Eric J. Bernhard, Amit Maity - Molecular Biology of the Cell 2004 被引用: 227
- Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins
著者: David Stokoe, Katrin Engel, David G. Campbell, Philip Cohen, Matthias Gaestel - FEBS Letters 1992 被引用: 574
- High Frequency of Coexistent Mutations of PIK3CA and PTEN Genes in Endometrial Carcinoma
著者: Katsutoshi Oda, David Stokoe, Yuji Taketani, Frank McCormick - Cancer Research 2005 被引用: 465
- Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes
著者: Xiaolan Hu, Howard M. Stern, Lin Ge, Carol O’Brien, Lauren E. Haydu, Cynthia D. Honchell, Peter M. Haverty, Brock A. Peters, Thomas D. Wu, Lukas C. Amler, John Chant, David Stokoe, Mark R. Lackner, Guy Cavet - Molecular Cancer Research 2009 被引用: 216
