Edward B. Lee
1999–2025 年に発表
- 別表記
- Edward B Lee
- 220
- 論文数
- 22,839
- 被引用数
- 79
- h 指数
- 190
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine62.3%
- Biochemistry, Genetics and Molecular Biology21.5%
- Neuroscience12.1%
- Computer Science1.2%
- Agricultural and Biological Sciences0.6%
- Immunology and Microbiology0.5%
- その他1.8%
トピック
- Alzheimer's disease research and treatments12.6%
- Amyotrophic Lateral Sclerosis Research8.2%
- Parkinson's Disease Mechanisms and Treatments5.6%
- Dementia and Cognitive Impairment Research4.6%
- Neuroinflammation and Neurodegeneration Mechanisms3.9%
- Neurogenetic and Muscular Disorders Research3.4%
- その他61.7%
共著者
- John Q. Trojanowski94
- David J. Irwin82
- Murray Grossman62
- David A. Wolk58
- Corey T. McMillan52
- Vivianna M. Van Deerlin50
- Virginia M.‐Y. Lee49
- John Robinson35
- Sharon X. Xie35
- Leslie M. Shaw34
- Alice Chen‐Plotkin22
- EunRan Suh21
- Sandhitsu R. Das21
- Katheryn A Q Cousins20
- Daniel T. Ohm19
- Theresa Schuck19
- Paul A. Yushkevich18
- Ranjit Ittyerah18
- Gábor G. Kovács16
- Lauren Elman15
- Sydney Lim15
- Gabor Mizsei14
- Karthik Prabhakaran14
- Daniel Weintraub13
全論文
- SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network
著者: Jian Hu, Xiangjie Li, Kyle Coleman, Amelia Schroeder, Nan Ma, David J. Irwin, Edward B. Lee, Russell T. Shinohara, Mingyao Li - Nature Methods 2021 被引用: 1,095
- Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
著者: Erik C. B. Johnson, Eric B. Dammer, Duc M. Duong, Lingyan Ping, Maotian Zhou, Luming Yin, Lenora A. Higginbotham, Andrew Guajardo, Bartholomew White, Juan C. Troncoso, Madhav Thambisetty, Thomas J. Montine, Edward B. Lee, John Q. Trojanowski, Thomas G. Beach, Eric M. Reiman, Vahram Haroutunian, Minghui Wang, Eric E. Schadt, Bin Zhang, Dennis W. Dickson, Nilüfer Ertekin‐Taner, Todd E. Golde, Vladislav Petyuk, Philip L. De Jager, David A. Bennett, Thomas S. Wingo, Srikant Rangaraju, Ihab Hajjar, Joshua M. Shulman, James J. Lah, Allan I. Levey, Nicholas T. Seyfried - Nature Medicine 2020 被引用: 1,060
- TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
著者: Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Colleen Lee, Alexander Bampton, Flora Lee, Laura Masino, Yue Qi, Sam Bryce-Smith, Ariana Gatt, Martina Hallegger, Delphine Fagegaltier, Hemali Phatnani, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B. Lee, Vivianna M. Van Deerlin, Neil A. Shneider, Ernest Fraenkel, Lyle W. Ostrow, Frank Baas, Noah Zaitlen, James D. Berry, Andrea Malaspina, Pietro Fratta, Gregory A. Cox, Leslie M. Thompson, Steven Finkbeiner, Efthimios Dardiotis, Timothy M. Miller, Siddharthan Chandran, Suvankar Pal, Eran Hornstein, Daniel J. MacGowan, Terry Heiman‐Patterson, Molly Hammell, Nikolaos A. Patsopoulos, Oleg Butovsky, Josh Dubnau, Avindra Nath, Robert Bowser, Matthew B. Harms, Eleonora Aronica, Mary Poss, Jennifer E. Phillips‐Cremins, John F. Crary, Nazem Atassi, Dale J. Lange, Darius J. Adams, Leonidas Stefanis, Marc Gotkine, Robert H. Baloh, Suma Babu, Towfique Raj, Sabrina Paganoni, Ophir Shalem, Colin Smith, Bin Zhang, Brent T. Harris, Iris Broce, Vivian E. Drory, John Ravits, Corey T. McMillan, Vilas Menon, Lani F. Wu, Steven J. Altschuler, Yossef Lerner, Rita Sattler, Kendall Van Keuren‐Jensen, Orit Rozenblatt–Rosen, Kerstin Lindblad‐Toh, Katharine Nicholson, Peter K. Gregersen, Jeong‐Ho Lee, Sulev Kõks, Stephen Muljo, Jia Newcombe, Emil K. Gustavsson, Sahba Seddighi, Joel F. Reyes, Steven L. Coon, Daniel M. Ramos, Giampietro Schiavo, Elizabeth Fisher, Towfique Raj, Maria Secrier, Tammaryn Lashley, Jernej Ule, Emanuele Buratti, Jack Humphrey, Michael E. Ward, Pietro Fratta - Nature 2022 被引用: 514
- Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated
著者: John Robinson, Edward B. Lee, Sharon X. Xie, Lior Rennert, EunRan Suh, Colin Bredenberg, Carrie Caswell, Vivianna M. Van Deerlin, Ning Yan, Ahmed H. Yousef, Howard I. Hurtig, Andrew Siderowf, Murray Grossman, Corey T. McMillan, Bruce L. Miller, John E. Duda, David J. Irwin, David A. Wolk, Lauren Elman, Leo McCluskey, Alice Chen‐Plotkin, Daniel Weintraub, Steven E. Arnold, Johannes Brettschneider, Virginia M.‐Y. Lee, John Q. Trojanowski - Brain 2018 被引用: 737
- Inferring super-resolution tissue architecture by integrating spatial transcriptomics with histology
著者: Daiwei Zhang, Amelia Schroeder, Hanying Yan, Haochen Yang, Jian Hu, Michelle Y. Y. Lee, Kyung S. Cho, Katalin Suszták, Xiaowei Xu, Michael D. Feldman, Edward B. Lee, Emma E. Furth, Linghua Wang, Mingyao Li - Nature Biotechnology 2024 被引用: 187
- Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study
著者: Johannes Attems, Jon B. Toledo, Lauren Walker, Ellen Gelpí, Steve Gentleman, Glenda M. Halliday, Tibor Hortobágyi, K. A. Jellinger, Gábor G. Kovács, Edward B. Lee, Seth Love, Kirsty E. McAleese, Peter T. Nelson, Manuela Neumann, Laura Parkkinen, Tuomo Polvikoski, Beata Sikorska, Colin Smith, Lea T. Grinberg, Dietmar Rudolf Thal, John Q. Trojanowski, Ian G. McKeith - Acta Neuropathologica 2021 被引用: 276
- Distribution patterns of tau pathology in progressive supranuclear palsy
著者: Gábor G. Kovács, Milica Ječmenica‐Lukić, David J. Irwin, Thomas Arzberger, Gesine Respondek, Edward B. Lee, David G. Coughlin, Armin Giese, Murray Grossman, Carolin Kurz, Corey T. McMillan, Ellen Gelpí, Yaroslau Compta, John C. van Swieten, Laura Donker Laat, Claire Troakes, Safa Al‐Sarraj, John Robinson, Sigrun Roeber, Sharon X. Xie, Virginia M.‐Y. Lee, John Q. Trojanowski, Günter U. Höglinger - Acta Neuropathologica 2020 被引用: 471
- Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
著者: David J. Irwin, Murray Grossman, Daniel Weintraub, Howard I. Hurtig, John E. Duda, Sharon X. Xie, Edward B. Lee, Vivianna M. Van Deerlin, Oscar L. López, Julia Kofler, Peter T. Nelson, Gregory A. Jicha, Randy Woltjer, Joseph F. Quinn, Jeffrey Kaye, James B. Leverenz, Debby W. Tsuang, Katelan Longfellow, Dora Yearout, Walter A. Kukull, C. Dirk Keene, Thomas J. Montine, Cyrus P. Zabetian, John Q. Trojanowski - The Lancet Neurology 2016 被引用: 591
- Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis
著者: Johannes Brettschneider, Kelly Del Tredici, Jon B. Toledo, John Robinson, David J. Irwin, Murray Grossman, EunRan Suh, Vivianna M. Van Deerlin, Elisabeth McCarty Wood, Young Min Baek, Linda K. Kwong, Edward B. Lee, Lauren Elman, Leo McCluskey, Lubin Fang, Simone Feldengut, Albert C. Ludolph, Virginia M.‐Y. Lee, Heiko Braak, John Q. Trojanowski - Annals of Neurology 2013 被引用: 1,066
- Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
著者: Oliver H. Tam, Nikolay V. Rozhkov, Regina Shaw, Duyang Kim, Isabel Hubbard, Samantha Fennessey, Nadia Propp, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B. Lee, Vivianna M. Van Deerlin, Neil A. Shneider, Ernest Fraenkel, Lyle W. Ostrow, Frank Baas, Noah Zaitlen, James D. Berry, Andrea Malaspina, Pietro Fratta, Gregory A. Cox, Leslie M. Thompson, Steven Finkbeiner, Efthimios Dardiotis, Jonathan Mill, Siddharthan Chandran, Suvankar Pal, Eran Hornstein, Daniel J. MacGowan, Terry Heiman‐Patterson, Molly Hammell, Nikolaos A. Patsopoulos, Oleg Butovsky, Josh Dubnau, Avindra Nath, Robert Bowser, Matt Harms, Eleonora Aronica, Mary Poss, Jennifer E. Phillips‐Cremins, John F. Crary, Nazem Atassi, Dale J. Lange, Darius J. Adams, Leonidas Stefanis, Marc Gotkine, Robert W. Baloh, Suma Babu, Towfique Raj, Sabrina Paganoni, Ophir Shalem, Colin Smith, Bin Zhang, Brent T. Harris, Delphine Fagegaltier, Brent T. Harris, Lyle W. Ostrow, Hemali Phatnani, John Ravits, Josh Dubnau, Molly Hammell - Cell Reports 2019 被引用: 333
- Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons
著者: Elaine Y. Liu, Jenny Russ, Christopher P. Cali, Jessica M. Phan, Alexandre Amlie‐Wolf, Edward B. Lee - Cell Reports 2019 被引用: 246
- LATE-NC staging in routine neuropathologic diagnosis: an update
著者: Peter T. Nelson, Edward B. Lee, Matthew D. Cykowski, Irina Alafuzoff, Konstantinos Arfanakis, Johannes Attems, Carol Brayne, María M. Corrada, Brittany N. Dugger, Margaret E. Flanagan, Bernardino Ghetti, Lea T. Grinberg, Murray Grossman, Michel J. Grothe, Glenda M. Halliday, Masato Hasegawa, Suvi R. K. Hokkanen, Sally Hunter, K. A. Jellinger, Claudia H. Kawas, C. Dirk Keene, Naomi Kouri, Gábor G. Kovács, James B. Leverenz, Caitlin S. Latimer, Ian R. Mackenzie, Qinwen Mao, Kirsty E. McAleese, Richard L. Merrick, Thomas J. Montine, Melissa E. Murray, Liisa Myllykangas, Sukriti Nag, Janna H. Neltner, Kathy L. Newell, Robert A. Rissman, Yuko Saito, S. Ahmad Sajjadi, Katherine E. Schwetye, Andrew F. Teich, Dietmar Rudolf Thal, Sandra O. Tomé, Juan C. Troncoso, Shih‐Hsiu J. Wang, Charles L. White, Thomas Wısnıewskı, Hyun‐Sik Yang, Julie A. Schneider, Dennis W. Dickson, Manuela Neumann - Acta Neuropathologica 2022 被引用: 176
- Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
著者: Gábor G. Kovács, Isidró Ferrer, Lea T. Grinberg, Irina Alafuzoff, Johannes Attems, Herbert Budka, Nigel J. Cairns, John F. Crary, Charles Duyckaerts, Bernardino Ghetti, Glenda M. Halliday, James W. Ironside, Seth Love, Ian R. Mackenzie, David G. Muñoz, Melissa E. Murray, Peter T. Nelson, Hitoshi Takahashi, John Q. Trojanowski, Olaf Ansorge, Thomas Arzberger, Atik Baborie, Thomas G. Beach, Kevin F. Bieniek, Eileen H. Bigio, István Bódi, Brittany N. Dugger, Mel Β. Feany, Ellen Gelpí, Stephen M. Gentleman, Giorgio Giaccone, Kimmo J. Hatanpaa, Richard Heale, Patrick R. Hof, Monika Hofer, Tibor Hortobágyi, K. A. Jellinger, Gregory A. Jicha, Paul G. Ince, Julia Kofler, Enikò Kövari, Jillian J. Kril, David Mann, Radoslav Matěj, Ann C. McKee, Catriona McLean, Ivan Milenković, Thomas J. Montine, Shigeo Murayama, Edward B. Lee, Jasmin Rahimi, Roberta Diehl Rodriguez, Annemieke J.M. Rozemüller, Julie A. Schneider, Christian Schultz, William W. Seeley, Danielle Seilhean, Colin Smith, Fabrizio Tagliavini, Masaki Takao, Dietmar Rudolf Thal, Jon B. Toledo, Markus Tolnay, Juan C. Troncoso, Harry V. Vinters, Serge Weis, Stephen B. Wharton, Charles L. White, Thomas Wısnıewskı, John Woulfe, Masahito Yamada, Dennis W. Dickson - Acta Neuropathologica 2015 被引用: 530
- Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
著者: Manuela Neumann, Linda K. Kwong, Edward B. Lee, Elisabeth Kremmer, Andrew Flatley, Yan Xu, Mark S. Forman, Dirk Troost, Hans A. Kretzschmar, John Q. Trojanowski, Virginia M.‐Y. Lee - Acta Neuropathologica 2009 被引用: 610
- Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
著者: Dylan V. Neel, Himanish Basu, Georgia Gunner, Matthew Bergstresser, Richard M. Giadone, Haeji Chung, Rui Miao, Vicky Chou, Eliza M. Brody, Xin Jiang, Edward B. Lee, Michelle Watts, Christine Marques, Aaron Held, Brian J. Wainger, Clotilde Lagier‐Tourenne, Yong‐Jie Zhang, Leonard Petrucelli, Tracy L. Young‐Pearse, Alice Chen‐Plotkin, Lee L. Rubin, Judy Lieberman, Isaac M. Chiu - Neuron 2023 被引用: 124
- Deciphering tumor ecosystems at super resolution from spatial transcriptomics with TESLA
著者: Jian Hu, Kyle Coleman, Daiwei Zhang, Edward B. Lee, Humam Kadara, Linghua Wang, Mingyao Li - Cell Systems 2023 被引用: 95
- APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer’s disease
著者: Aivi T. Nguyen, Kui Wang, Gang Hu, Xuran Wang, Zhen Miao, Joshua A. Azevedo, EunRan Suh, Vivianna M. Van Deerlin, David Choi, Kathryn Roeder, Mingyao Li, Edward B. Lee - Acta Neuropathologica 2020 被引用: 281
- The development and convergence of co-pathologies in Alzheimer’s disease
著者: John Robinson, Hayley Richardson, Sharon X. Xie, EunRan Suh, Vivianna M. Van Deerlin, Brian Alfaro, Nicholas Loh, Matias Porras-Paniagua, Jeffrey Nirschl, David A. Wolk, Virginia M.‐Y. Lee, Edward B. Lee, John Q. Trojanowski - Brain 2020 被引用: 203
- Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated
著者: John Robinson, Sharon X. Xie, Daniel R. Baer, EunRan Suh, Vivianna M. Van Deerlin, Nicholas Loh, David J. Irwin, Corey T. McMillan, David A. Wolk, Alice Chen‐Plotkin, Daniel Weintraub, Theresa Schuck, Virginia M.‐Y. Lee, John Q. Trojanowski, Edward B. Lee - Brain 2023 被引用: 166
- Tau deposition patterns are associated with functional connectivity in primary tauopathies
著者: Nicolai Franzmeier, Matthias Brendel, Leonie Beyer, Luna Slemann, Gábor G. Kovács, Thomas Arzberger, Carolin Kurz, Gesine Respondek, Milica Ječmenica‐Lukić, Davina Biel, Anna Rubinski, Lukas Frontzkowski, Selina Hummel, André Müller, Anika Finze, Carla Palleis, Emanuel Joseph, Endy Weidinger, Sabrina Katzdobler, Mengmeng Song, Gloria Biechele, Maike Kern, Maximilian Scheifele, Boris‐Stephan Rauchmann, Robert Perneczky, Michael Rullman, Marianne Patt, Andreas Schildan, Henryk Barthel, Osama Sabri, Jost J. Rumpf, Matthias L. Schroeter, Joseph Claßen, Victor L. Villemagne, John Seibyl, Andrew Stephens, Edward B. Lee, David G. Coughlin, Armin Giese, Murray Grossman, Corey T. McMillan, Ellen Gelpí, Laura Molina‐Porcel, Yaroslau Compta, John C. van Swieten, Laura Donker Laat, Claire Troakes, Safa Al‐Sarraj, John Robinson, Sharon X. Xie, David J. Irwin, Sigrun Roeber, Jochen Herms, Mikael Simons, Peter Bartenstein, Virginia M. Lee, John Q. Trojanowski, Johannes Levin, Günter U. Höglinger, Michael Ewers - Nature Communications 2022 被引用: 108
- Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy
著者: Shanu F. Roemer, Lea T. Grinberg, John F. Crary, William W. Seeley, Ann C. McKee, Gábor G. Kovács, Thomas G. Beach, Charles Duyckaerts, Isidro A. Ferrer, Ellen Gelpí, Edward B. Lee, Tamás Révész, Charles L. White, Mari Yoshida, Felipe Luiz Pereira, Kristen Whitney, Nikhil B Ghayal, Dennis W. Dickson - Acta Neuropathologica 2022 被引用: 134
- GPNMB confers risk for Parkinson’s disease through interaction with α-synuclein
著者: Maria E. Diaz‐Ortiz, Yunji Seo, Marijan Posavi, Marc Carceles Cordon, Elisia Clark, Nimansha Jain, Rakshita A. Charan, Michael D. Gallagher, Travis L. Unger, Noor Amari, R. Tyler Skrinak, Roseanne Davila‐Rivera, Eliza M. Brody, Noah Han, Rebecca Zack, Vivianna M. Van Deerlin, Thomas F. Tropea, Kelvin C. Luk, Edward B. Lee, Daniel Weintraub, Alice Chen‐Plotkin - Science 2022 被引用: 152
- Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
著者: Edward B. Lee, Virginia M.‐Y. Lee, John Q. Trojanowski - Nature reviews. Neuroscience 2011 被引用: 664
- Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo
著者: Sílvia Porta, Yan Xu, Clark R. Restrepo, Linda K. Kwong, Bin Zhang, Hannah J. Brown, Edward B. Lee, John Q. Trojanowski, Virginia M.‐Y. Lee - Nature Communications 2018 被引用: 254
