Ernesto Freire
1978–2021 年に発表
- 129
- 論文数
- 20,201
- 被引用数
- 90
- h 指数
- 129
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology39%
- Medicine19.2%
- Immunology and Microbiology13.4%
- Computer Science8.8%
- Chemistry8.5%
- Pharmacology, Toxicology and Pharmaceutics3.3%
- その他7.8%
トピック
- Protein Structure and Dynamics8.5%
- Computational Drug Discovery Methods7%
- HIV Research and Treatment5.3%
- Enzyme Structure and Function3.7%
- Lipid Membrane Structure and Behavior3.2%
- thermodynamics and calorimetric analyses3.2%
- その他69.1%
共著者
- Arne Schön29
- Adrián Velázquez‐Campoy16
- Irene Luque12
- Joseph Sodroski12
- Yoshiaki Kiso12
- Amos B. Smith11
- Navid Madani11
- L. Mario Amzel9
- Peter D. Kwong9
- Dong Xie8
- Kenneth P. Murphy7
- Matthew J. Todd7
- Hiroyasu Ohtaka6
- Javier Gómez6
- Joel R. Courter6
- Judith M. LaLonde6
- Stephanie A. Leavitt6
- Usman Bacha6
- Vincent J. Hilser6
- Amy M. Princiotto5
- Rodney L. Biltonen5
- Yoshio Hayashi5
- Yuko Kawasaki5
- Azin Nezami4
全論文
- Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo
著者: Qingguo Xu, Laura M. Ensign, Nicholas J. Boylan, Arne Schön, Xiaoqun Gong, Jeh‐Chang Yang, Nicholas W. Lamb, Shutian Cai, Tao Yu, Ernesto Freire, Justin Hanes - ACS Nano 2015 被引用: 554
- Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
著者: Young Do Kwon, Marie Pancera, Priyamvada Acharya, Ivelin S. Georgiev, Emma T. Crooks, Jason Gorman, M. Gordon Joyce, Miklós Guttman, Xiaochu Ma, Sandeep Narpala, Cinque Soto, Daniel S. Terry, Yongping Yang, Tongqing Zhou, Göran Ahlsén, Robert T. Bailer, Michael Chambers, Gwo‐Yu Chuang, Nicole A. Doria-Rose, Aliaksandr Druz, Mark A. Hallen, Adam Harned, Tatsiana Kirys, Mark K. Louder, Sijy O’Dell, Gilad Ofek, Keiko Osawa, Madhu Prabhakaran, Mallika Sastry, Guillaume B. E. Stewart-Jones, Jonathan Stuckey, Paul V. Thomas, Tishina Tittley, Constance Williams, Baoshan Zhang, Hong Zhao, Zhou Zhou, Bruce R. Donald, Lawrence K. Lee, Susan Zolla‐Pazner, Ulrich Baxa, Arne Schön, Ernesto Freire, Lawrence Shapiro, Kelly K. Lee, James Arthos, James B. Munro, Scott C. Blanchard, Walther Mothes, James Μ. Binley, Adrian B. McDermott, John R. Mascola, Peter D. Kwong - Nature Structural & Molecular Biology 2015 被引用: 368
- A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
著者: Neville K. Kisalu, Azza H. Idris, Connor Weidle, Yevel Flores-García, Barbara J. Flynn, Brandon K. Sack, Sean C. Murphy, Arne Schön, Ernesto Freire, Joseph R. Francica, A. B. Miller, Jason Gregory, Sandra March, Hua-Xin Liao, Barton F. Haynes, Kevin Wiehe, Ashley M. Trama, Kevin O. Saunders, Morgan A. Gladden, Anthony Monroe, Mattia Bonsignori, Masaru Kanekiyo, Adam K. Wheatley, Adrian B. McDermott, S. Katie Farney, Gwo‐Yu Chuang, Baoshan Zhang, Natasha KC, Sumana Chakravarty, Peter D. Kwong, Photini Sinnis, Sangeeta N. Bhatia, Stefan H. I. Kappe, B. Kim Lee Sim, Stephen L. Hoffman, Fidel Zavala, Marie Pancera, Robert A. Seder - Nature Medicine 2018 被引用: 314
- HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
著者: Peter D. Kwong, Michael L. Doyle, David J. Casper, Claudia Cicala, Stephanie A. Leavitt, Shahzad Majeed, Tavis D. Steenbeke, Miro Venturi, Irwin Chaiken, Michael Fung, Hermann Katinger, Paul W.H.I. Parren, James E. Robinson, Donald Van Ryk, Liping Wang, Dennis R. Burton, Ernesto Freire, Richard T. Wyatt, Joseph Sodroski, Wayne A. Hendrickson, James Arthos - Nature 2002 被引用: 903
- Isothermal titration calorimetry to determine association constants for high-affinity ligands
著者: Adrián Velázquez‐Campoy, Ernesto Freire - Nature Protocols 2006 被引用: 334
- Do enthalpy and entropy distinguish first in class from best in class?
著者: Ernesto Freire - Drug Discovery Today 2008 被引用: 482
- Isothermal titration calorimetry
著者: Ernesto Freire, Obdulio López Mayorga, Martin Straume - Analytical Chemistry 1990 被引用: 593
- Isothermal Titration Calorimetry
著者: Adrián Velázquez‐Campoy, Hiroyasu Ohtaka, Azin Nezami, Salman Muzammil, Ernesto Freire - Current Protocols in Cell Biology 2004 被引用: 227
- Direct measurement of protein binding energetics by isothermal titration calorimetry
著者: Stephanie A. Leavitt, Ernesto Freire - Current Opinion in Structural Biology 2001 被引用: 687
- Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env
著者: Ivelin S. Georgiev, Michael Joyce, Yongping Yang, Mallika Sastry, Baoshan Zhang, Ulrich Baxa, Rita E. Chen, Aliaksandr Druz, Christopher R. Lees, Sandeep Narpala, Arne Schön, Joseph Van Galen, Gwo‐Yu Chuang, Jason Gorman, Adam Harned, Marie Pancera, Guillaume B. E. Stewart-Jones, Cheng Cheng, Ernesto Freire, Adrian B. McDermott, John R. Mascola, Peter D. Kwong - Journal of Virology 2015 被引用: 131
- The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
著者: Alon Herschhorn, Christopher Gu, Francesca Moraca, Xiaochu Ma, Mark P. Farrell, Amos B. Smith, Marie Pancera, Peter D. Kwong, Arne Schön, Ernesto Freire, Cameron F. Abrams, Scott C. Blanchard, Walther Mothes, Joseph Sodroski - Nature Communications 2017 被引用: 116
- Adding calorimetric data to decision making in lead discovery: a hot tip
著者: John E. Ladbury, G. Klebe, Ernesto Freire - Nature Reviews Drug Discovery 2009 被引用: 399
- Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529
著者: Marie Pancera, Yen‐Ting Lai, Tatsiana Bylund, Aliaksandr Druz, Sandeep Narpala, Sijy O’Dell, Arne Schön, Robert T. Bailer, Gwo‐Yu Chuang, Hui Geng, Mark K. Louder, Reda Rawi, Djadé I. Soumana, Andrés Finzi, Alon Herschhorn, Navid Madani, Joseph Sodroski, Ernesto Freire, David R. Langley, John R. Mascola, Adrian B. McDermott, Peter D. Kwong - Nature Chemical Biology 2017 被引用: 128
- The heat capacity of proteins
著者: Javier Gómez, Vincent J. Hilser, Dong Xie, Ernesto Freire - Proteins Structure Function and Bioinformatics 1995 被引用: 434
- Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: Design, synthesis, biological evaluation, and docking studies
著者: Thanigaimalai Pillaiyar, Sho Konno, Takehito Yamamoto, Yuji Koiwai, Akihiro Taguchi, Kentaro Takayama, Fumika Yakushiji, Kenichi Akaji, Shen-En Chen, Aurash Naser‐Tavakolian, Arne Schön, Ernesto Freire, Yoshio Hayashi - European Journal of Medicinal Chemistry 2013 被引用: 106
- Structure-based Calculation of the Equilibrium Folding Pathway of Proteins. Correlation with Hydrogen Exchange Protection Factors
著者: Vincent J. Hilser, Ernesto Freire - Journal of Molecular Biology 1996 被引用: 255
- Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins
著者: Zhihai Si, Navid Madani, Jason M. Cox, Jason J. Chruma, Jeffrey C. Klein, Arne Schön, Ngoc Phan, Liping Wang, Alyssa C. Biorn, Simon Cocklin, Irwin Chaiken, Ernesto Freire, Amos B. Smith, Joseph Sodroski - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 被引用: 255
- The structural distribution of cooperative interactions in proteins: Analysis of the native state ensemble
著者: Vincent J. Hilser, David W. Dowdy, Terrence G. Oas, Ernesto Freire - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 被引用: 222
- CD4 mimetics sensitize HIV-1-infected cells to ADCC
著者: Jonathan Richard, Maxime Veillette, Nathalie Brassard, Shilpa S. Iyer, Michel Roger, Loı̈c Martin, Marzena Pazgier, Arne Schön, Ernesto Freire, Jean‐Pierre Routy, Amos B. Smith, Jongwoo Park, David M. Jones, Joel R. Courter, Bruno Melillo, Daniel E. Kaufmann, Beatrice H. Hahn, Sallie R. Permar, Barton F. Haynes, Navid Madani, Joseph Sodroski, Andrés Finzi - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 被引用: 158
- Characterization of Protein-Protein Interactions by Isothermal Titration Calorimetry
著者: Adrián Velázquez‐Campoy, Stephanie A. Leavitt, Ernesto Freire - Methods in molecular biology 2015 被引用: 151
- Finding a better path to drug selectivity
著者: Yuko Kawasaki, Ernesto Freire - Drug Discovery Today 2011 被引用: 136
- Long-Range Cooperative Interactions Modulate Dimerization in SARS 3CLpro
著者: Jennifer Barrila, Usman Bacha, Ernesto Freire - Biochemistry 2006 被引用: 89
- Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition
著者: Bruno Melillo, Shuaiyi Liang, Jongwoo Park, Arne Schön, Joel R. Courter, Judith M. LaLonde, Daniel J. Wendler, Amy M. Princiotto, Michael S. Seaman, Ernesto Freire, Joseph Sodroski, Navid Madani, Wayne A. Hendrickson, Amos B. Smith - ACS Medicinal Chemistry Letters 2016 被引用: 104
- Temperature stability of proteins: Analysis of irreversible denaturation using isothermal calorimetry
著者: Arne Schön, Benjamin R. Clarkson, María del Sol Jaime, Ernesto Freire - Proteins Structure Function and Bioinformatics 2017 被引用: 85
