F. Peter Guengerich
1973–2025 年に発表
- 別表記
- F.Peter Guengerich
- 389
- 論文数
- 73,115
- 被引用数
- 146
- h 指数
- 385
- i10 指数
被引用数
引用元
国・地域
機関
- Vanderbilt University1.3%
- National Institutes of Health0.8%
- University of Washington0.7%
- Inserm0.7%
- University of Michigan0.6%
- National Cancer Institute0.6%
- その他95.3%
分野
- Pharmacology, Toxicology and Pharmaceutics32.8%
- Biochemistry, Genetics and Molecular Biology26.9%
- Medicine21.3%
- Agricultural and Biological Sciences3.8%
- Chemistry3.8%
- Computer Science3.8%
- その他7.6%
トピック
- Pharmacogenetics and Drug Metabolism14.7%
- Drug Transport and Resistance Mechanisms5%
- Computational Drug Discovery Methods4.4%
- Carcinogens and Genotoxicity Assessment2.6%
- Drug-Induced Hepatotoxicity and Protection2.2%
- Eicosanoids and Hypertension Pharmacology2.1%
- その他69%
共著者
- Tsutomu Shimada54
- Hiroshi Yamazaki38
- Elizabeth M. J. Gillam17
- Philippe Beaune16
- Martha V. Martin15
- Chul‐Ho Yun14
- Donghak Kim12
- Ghazi A. Dannan12
- Yune‐Fang Ueng12
- Laurence S. Kaminsky11
- Michael R. Waterman10
- Frank J. Gonzalez9
- Kevin D. McCarty9
- Martin Egli9
- Norie Murayama9
- David J. Waxman8
- Fred F. Kadlubar8
- Samuel M. Cohen8
- Stephen S. Hecht8
- William W. Johnson8
- Galina I. Lepesheva7
- Jeong‐Yun Choi7
- Kiyoshi Inoue7
- M V Martin7
全論文
- Cytochrome P450 and Chemical Toxicology
著者: F. Peter Guengerich - Chemical Research in Toxicology 2007 被引用: 1,685
- Mechanisms of Cytochrome P450-Catalyzed Oxidations
著者: F. Peter Guengerich - ACS Catalysis 2018 被引用: 434
- Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals
著者: Slobodan Rendić, F. Peter Guengerich - Chemical Research in Toxicology 2014 被引用: 460
- Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis
著者: Tatiana Y. Hargrove, Laura Friggeri, Z. Wawrzak, Aidong Qi, William J. Hoekstra, Robert J. Schotzinger, John D. York, F. Peter Guengerich, Galina I. Lepesheva - Journal of Biological Chemistry 2017 被引用: 408
- Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development
著者: F. Peter Guengerich - Drug Metabolism and Pharmacokinetics 2010 被引用: 386
- Recent Structural Insights into Cytochrome P450 Function
著者: F. Peter Guengerich, Michael R. Waterman, Martin Egli - Trends in Pharmacological Sciences 2016 被引用: 380
- Formation and Cleavage of C–C Bonds by Enzymatic Oxidation–Reduction Reactions
著者: F. Peter Guengerich, Francis K. Yoshimoto - Chemical Reviews 2018 被引用: 285
- CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism
著者: F. Peter Guengerich - The Annual Review of Pharmacology and Toxicology 1999 被引用: 1,272
- Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity
著者: F. Peter Guengerich - Chemical Research in Toxicology 2001 被引用: 1,639
- Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
著者: Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura, Yukiharu Inui, F. Peter Guengerich - Journal of Pharmacology and Experimental Therapeutics 1994 被引用: 2,786
- A history of the roles of cytochrome P450 enzymes in the toxicity of drugs
著者: F. Peter Guengerich - Toxicological Research 2020 被引用: 136
- Measurement of cytochrome P450 and NADPH–cytochrome P450 reductase
著者: F. Peter Guengerich, Martha V. Martin, Christal D. Sohl, Qian Cheng - Nature Protocols 2009 被引用: 385
- Activation and detoxication of aflatoxin B1
著者: F. Peter Guengerich, William W. Johnson, Tsutomu Shimada, Yune‐Fang Ueng, Hiroshi Yamazaki, Sophie Langouët - Mutation research. Fundamental and molecular mechanisms of mutagenesis 1998 被引用: 343
- Learning to Solve Markovian Decision Processes
著者: F. Peter Guengerich - Chemico-Biological Interactions 1993 被引用: 111
- Inhibition of Cytochrome P450 Enzymes by Drugs-Molecular Basis and Practical Applications
著者: F. Peter Guengerich - Biomolecules & Therapeutics 2021 被引用: 57
- Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications
著者: Zhong Li, Yuanyuan Jiang, F. Peter Guengerich, Li Ma, Shengying Li, Wei Zhang - Journal of Biological Chemistry 2019 被引用: 251
- Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs
著者: Tatiana Y. Hargrove, Z. Wawrzak, David C. Lamb, F. Peter Guengerich, Galina I. Lepesheva - Journal of Biological Chemistry 2015 被引用: 150
- Cytochrome P450s and other enzymes in drug metabolism and toxicity
著者: F. Peter Guengerich - The AAPS Journal 2006 被引用: 624
- The Role of Oxysterols in Human Cancer
著者: Alžběta Kloudová, F. Peter Guengerich, Pavel Souček - Trends in Endocrinology and Metabolism 2017 被引用: 193
- Mechanism of the Third Oxidative Step in the Conversion of Androgens to Estrogens by Cytochrome P450 19A1 Steroid Aromatase
著者: Francis K. Yoshimoto, F. Peter Guengerich - Journal of the American Chemical Society 2014 被引用: 121
- Roles of cytochrome P450 enzymes in pharmacology and toxicology: Past, present, and future
著者: F. Peter Guengerich - Advances in pharmacology 2022 被引用: 39
- A requirement for an active proton delivery network supports a compound I-mediated C–C bond cleavage in CYP51 catalysis
著者: Tatiana Y. Hargrove, Z. Wawrzak, F. Peter Guengerich, Galina I. Lepesheva - Journal of Biological Chemistry 2020 被引用: 38
- Complex reactions catalyzed by cytochrome P450 enzymes
著者: Emre M. Isin, F. Peter Guengerich - Biochimica et Biophysica Acta (BBA) - General Subjects 2006 被引用: 447
- Unusual Cytochrome P450 Enzymes and Reactions
著者: F. Peter Guengerich, Andrew W. Munro - Journal of Biological Chemistry 2013 被引用: 348
