Frances M. Ashcroft
1981–2024 年に発表
- 136
- 論文数
- 32,282
- 被引用数
- 96
- h 指数
- 136
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine48.1%
- Biochemistry, Genetics and Molecular Biology37%
- Neuroscience9.3%
- Nursing1.1%
- Chemistry0.7%
- Engineering0.6%
- その他3.2%
トピック
- Pancreatic function and diabetes11.1%
- Ion channel regulation and function4.9%
- Diabetes and associated disorders3.3%
- Metabolism, Diabetes, and Cancer3.2%
- Adipose Tissue and Metabolism3.1%
- RNA modifications and cancer2.9%
- その他71.5%
共著者
- Patrik Rorsman26
- Peter Proks26
- Fiona M. Gribble24
- Roger Cox13
- Frank Reimann12
- Kenju Shimomura12
- Andrei I. Tarasov11
- Andrew T. Hattersley10
- Christophe A. Girard10
- Stephen J. Tucker10
- Paul A. Smith8
- Quan Zhang8
- Mark S.P. Sansom7
- Sian Ellard7
- Elizabeth Haythorne6
- Melissa F. Brereton6
- Reshma Ramracheya6
- Anna L. Gloyn5
- Anne Clark5
- Carina Ämmälä5
- Natascia Vedovato5
- Samuel Usher5
- Sarah E. Flanagan5
- Stephan C. Collins5
全論文
- Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men
著者: Patrik Rorsman, Frances M. Ashcroft - Physiological Reviews 2017 被引用: 776
- The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase
著者: Thomas Gerken, Christophe A. Girard, Yi‐Chun Loraine Tung, Celia J. Webby, Vladimı́r Saudek, Kirsty S. Hewitson, Giles S.H. Yeo, M.A. McDonough, Sharon L. Cunliffe, Luke A. McNeill, Juris Galvanovskis, Patrik Rorsman, Peter Robins, Xavier Prieur, Anthony P. Coll, Marcella Ma, Z Jovanović, I. Sadaf Farooqi, Barbara Sedgwick, Inês Barroso, Tomas Lindahl, Chris P. Ponting, Frances M. Ashcroft, Stephen O’Rahilly, Christopher J. Schofield - Science 2007 被引用: 1,536
- Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells
著者: Elizabeth Haythorne, Maria Rohm, Martijn van de Bunt, Melissa F. Brereton, Andrei I. Tarasov, Thomas S. Blacker, G. Sachse, Mariana Silva dos Santos, Raúl Terrón Expósito, Simon Davis, Otto Baba, Román Fischer, Michael R. Duchen, Patrik Rorsman, James I. MacRae, Frances M. Ashcroft - Nature Communications 2019 被引用: 326
- Diabetes Mellitus and the β Cell: The Last Ten Years
著者: Frances M. Ashcroft, Patrik Rorsman - Cell 2012 被引用: 911
- Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells
著者: Elizabeth Haythorne, Matthew Lloyd, John Walsby-Tickle, Andrei I. Tarasov, Jonas B. Sandbrink, Idoia Portillo, Raúl Terrón Expósito, G. Sachse, Małgorzata Cyranka, Maria Rohm, Patrik Rorsman, James McCullagh, Frances M. Ashcroft - Nature Communications 2022 被引用: 105
- Overexpression of Fto leads to increased food intake and results in obesity
著者: Chris Church, Lee Moir, Fiona McMurray, Christophe A. Girard, Gareth Banks, Lydia Teboul, Sara Wells, Jens C. Brüning, Patrick M. Nolan, Frances M. Ashcroft, Roger Cox - Nature Genetics 2010 被引用: 721
- Insulin Action in AgRP-Expressing Neurons Is Required for Suppression of Hepatic Glucose Production
著者: A. Christine Könner, Ruth Janoschek, Leona Plum, Sabine D. Jordan, Eva Rother, Xiaosong Ma, Chun Xu, Pablo J. Enriori, Brigitte Hampel, Gregory S. Barsh, C. Ronald Kahn, Michael A. Cowley, Frances M. Ashcroft, Jens C. Brüning - Cell Metabolism 2007 被引用: 691
- Monitoring glycolytic dynamics in single cells using a fluorescent biosensor for fructose 1,6-bisphosphate
著者: John N. Koberstein, Melissa L. Stewart, Chadwick B. Smith, Andrei I. Tarasov, Frances M. Ashcroft, Philip A. Stork, Richard H. Goodman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 被引用: 61
- Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells
著者: Frances M. Ashcroft, D E Harrison, Stephen J.H. Ashcroft - Nature 1984 被引用: 1,124
- Sulfonylurea Stimulation of Insulin Secretion
著者: Peter Proks, Frank Reimann, Nicholas Green, Fiona M. Gribble, Frances M. Ashcroft - Diabetes 2002 被引用: 504
- A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice
著者: Ayo A. Toye, Jonathan D. Lippiat, Peter Proks, Kenju Shimomura, Liz Bentley, A. Hugill, Vesna Mijat, Michelle Goldsworthy, Lee Moir, Andrew R. Haynes, J. Quarterman, Helen Freeman, Frances M. Ashcroft, Roger Cox - Diabetologia 2005 被引用: 451
- Glucokinase activity in diabetes: too much of a good thing?
著者: Frances M. Ashcroft, Matthew Lloyd, Elizabeth Haythorne - Trends in Endocrinology and Metabolism 2022 被引用: 60
- Reversible changes in pancreatic islet structure and function produced by elevated blood glucose
著者: Melissa F. Brereton, Michaela Iberl, Kenju Shimomura, Quan Zhang, Alice E. Adriaenssens, Peter Proks, Ioannis Spiliotis, William Dace, Katia K. Mattis, Reshma Ramracheya, Fiona M. Gribble, Frank Reimann, Anne Clark, Patrik Rorsman, Frances M. Ashcroft - Nature Communications 2014 被引用: 252
- Activating Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes
著者: Anna L. Gloyn, Ewan R. Pearson, Jennifer F. Antcliff, Peter Proks, G.J. Bruining, Annabelle S. Slingerland, Neville J. Howard, Shubha Srinivasan, Jose M. C. L Silva, Janne Molnes, Emma L. Edghill, Timothy M. Frayling, I. Karen Temple, Deborah Mackay, Julian Hamilton‐Shield, Zdenĕk Šumnı́k, Adrian van Rhijn, J K Wales, P M Clark, Shaun Gorman, Javier Aisenberg, Sian Ellard, Pål R. Njølstad, Frances M. Ashcroft, Andrew T. Hattersley - New England Journal of Medicine 2004 被引用: 1,144
- FTO influences adipogenesis by regulating mitotic clonal expansion
著者: Myrte Merkestein, Samantha Laber, Fiona McMurray, Daniel S. Andrew, G. Sachse, Jeremy Sanderson, Mengdi Li, Samuel Usher, Dyan Sellayah, Frances M. Ashcroft, Roger Cox - Nature Communications 2015 被引用: 238
- Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion
著者: Elisa Vergari, Jakob G. Knudsen, Reshma Ramracheya, Albert Salehi, Quan Zhang, Julie Adam, Ingrid Wernstedt Asterholm, Anna Benrick, Linford J.B. Briant, Margarita V. Chibalina, Fiona M. Gribble, Alexander Hamilton, Benoît Hastoy, Frank Reimann, Nils J. G. Rorsman, Ioannis Spiliotis, Andrei I. Tarasov, Yan‐Ling Wu, Frances M. Ashcroft, Patrik Rorsman - Nature Communications 2019 被引用: 161
- Q&A: insulin secretion and type 2 diabetes: why do β-cells fail?
著者: James Cantley, Frances M. Ashcroft - BMC Biology 2015 被引用: 147
- ATP-sensitive potassium channelopathies: focus on insulin secretion
著者: Frances M. Ashcroft - Journal of Clinical Investigation 2005 被引用: 634
- PPAR gamma 2 Prevents Lipotoxicity by Controlling Adipose Tissue Expandability and Peripheral Lipid Metabolism
著者: Gema Medina‐Gómez, Sarah L. Gray, Laxman Yetukuri, Kenju Shimomura, Sam Virtue, Mark Campbell, Ruth Curtis, Mercedes Jimenez‐Liñan, Margaret Blount, Giles S.H. Yeo, Miguel López, Tuulikki Seppänen‐Laakso, Frances M. Ashcroft, Matej Orešič, Antonio Vidal‐Puig - PLoS Genetics 2007 被引用: 424
- Switching from Insulin to Oral Sulfonylureas in Patients with Diabetes Due to Kir6.2 Mutations
著者: Ewan R. Pearson, Isabelle Flechtner, Pål R. Njølstad, Maciej T. Małecki, Sarah E. Flanagan, Brian Larkin, Frances M. Ashcroft, I Klimeś, Ethel Codner, Violeta Iotova, Annabelle S. Slingerland, Julian Hamilton‐Shield, Jean‐Jacques Robert, Jens J. Holst, Penny Clark, Sian Ellard, Oddmund Sövik, Michel Polak, Andrew T. Hattersley - New England Journal of Medicine 2006 被引用: 986
- Deletion of Nicotinamide Nucleotide Transhydrogenase
著者: Helen Freeman, Alison Hugill, Neil Dear, Frances M. Ashcroft, Roger Cox - Diabetes 2006 被引用: 314
- KATP channels and islet hormone secretion: new insights and controversies
著者: Frances M. Ashcroft, Patrik Rorsman - Nature Reviews Endocrinology 2013 被引用: 261
- Electrophysiology of the pancreatic β-cell
著者: Frances M. Ashcroft, Patrik Rorsman - Progress in Biophysics and Molecular Biology 1989 被引用: 1,129
- Role of KATP Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes
著者: Quan Zhang, Reshma Ramracheya, Carolina Lahmann, Andrei I. Tarasov, Martin Bengtsson, Orit Braha, Matthias Braun, Melissa F. Brereton, Stephan C. Collins, Juris Galvanovskis, Alejandro González, Lukas N. Groschner, Nils J. G. Rorsman, Albert Salehi, Mary E. Travers, Jonathan N. Walker, Anna L. Gloyn, Fiona M. Gribble, Paul Johnson, Frank Reimann, Frances M. Ashcroft, Patrik Rorsman - Cell Metabolism 2013 被引用: 225
