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Frank L. Heppner

1967–2025 年に発表

135
論文数
33,465
被引用数
82
h 指数
130
i10 指数

被引用数

Frank L. Heppner の年別被引用数1969 年: 被引用 1 件1973 年: 被引用 1 件1976 年: 被引用 1 件1981 年: 被引用 1 件1986 年: 被引用 1 件1987 年: 被引用 1 件1989 年: 被引用 1 件1993 年: 被引用 1 件1994 年: 被引用 2 件1995 年: 被引用 3 件1996 年: 被引用 3 件1997 年: 被引用 1 件1998 年: 被引用 4 件1999 年: 被引用 3 件2000 年: 被引用 6 件2001 年: 被引用 24 件2002 年: 被引用 39 件2003 年: 被引用 62 件2004 年: 被引用 82 件2005 年: 被引用 86 件2006 年: 被引用 127 件2007 年: 被引用 123 件2008 年: 被引用 136 件2009 年: 被引用 166 件2010 年: 被引用 227 件2011 年: 被引用 183 件2012 年: 被引用 290 件2013 年: 被引用 335 件2014 年: 被引用 348 件2015 年: 被引用 371 件2016 年: 被引用 390 件2017 年: 被引用 442 件2018 年: 被引用 558 件2019 年: 被引用 1,175 件2020 年: 被引用 1,450 件2021 年: 被引用 1,824 件2022 年: 被引用 1,649 件2023 年: 被引用 1,361 件2024 年: 被引用 1,841 件2025 年: 被引用 1,055 件2026 年: 被引用 31 件1970〜1972 年は被引用が無いため表示していません1974〜1975 年は被引用が無いため表示していません1977〜1980 年は被引用が無いため表示していません1982〜1985 年は被引用が無いため表示していません1988 年は被引用が無いため表示していません1990〜1992 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 5,170 件、この内訳の 24.2%ドイツ: 引用元論文 2,155 件、この内訳の 10.1%中国: 引用元論文 2,151 件、この内訳の 10%イギリス: 引用元論文 1,459 件、この内訳の 6.8%カナダ: 引用元論文 837 件、この内訳の 3.9%イタリア: 引用元論文 808 件、この内訳の 3.8%フランス: 引用元論文 766 件、この内訳の 3.6%スイス: 引用元論文 686 件、この内訳の 3.2%オランダ: 引用元論文 665 件、この内訳の 3.1%オーストラリア: 引用元論文 523 件、この内訳の 2.4%スペイン: 引用元論文 517 件、この内訳の 2.4%日本: 引用元論文 506 件、この内訳の 2.4%
0%24.2%その他 24.1%

機関

分野

  • Medicine38.8%
  • Neuroscience29.1%
  • Biochemistry, Genetics and Molecular Biology17.1%
  • Immunology and Microbiology9.2%
  • Computer Science1.8%
  • Engineering0.9%
  • その他3.1%

トピック

  • Neuroinflammation and Neurodegeneration Mechanisms11.9%
  • Alzheimer's disease research and treatments5.1%
  • Immune cells in cancer3.8%
  • Glioma Diagnosis and Treatment3.4%
  • Tryptophan and brain disorders2.4%
  • Long-Term Effects of COVID-192%
  • その他71.4%

共著者

全論文

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  1. Microglia states and nomenclature: A field at its crossroads

    著者: Rosa Chiara Paolicelli, Amanda Sierra, Beth Stevens, Marie‐Ève Tremblay, Adriano Aguzzi, Bahareh Ajami, Ido Amit, Étienne Audinat, Ingo Bechmann, Mariko L. Bennett, F. Chris Bennett, Alain Bessis, Knut Biber, Staci D. Bilbo, Mathew Blurton‐Jones, Erik Boddeke, Dora Brites, Bert Brône, Guy C. Brown, Oleg Butovsky, Monica J. Carson, Bernardo Castellano, Marco Colonna, Sally A. Cowley, Colm Cunningham, Dimitrios Davalos, Philip L. De Jager, Bart De Strooper, Ádám Dénes, Bart J. L. Eggen, Ukpong B. Eyo, Elena Galea, Sonia Garel, Florent Ginhoux, Christopher K. Glass, Özgün Gökçe, Diego Gómez‐Nicola, Berta González, Siamon Gordon, Manuel B. Graeber, Andrew D. Greenhalgh, Pierre Gressèns, Melanie Greter, David H. Gutmann, Christian Haass, Michael T. Heneka, Frank L. Heppner, Soyon Hong, David Hume, Steffen Jung, Helmut Kettenmann, Jonathan Kipnis, Ryuta Koyama, Greg Lemke, Marina A. Lynch, Ania K. Majewska, Marzia Malcangio, Tarja Malm, Renzo Mancuso, Takahiro Masuda, Michela Matteoli, Barry W. McColl, Véronique E. Miron, Anna V. Molofsky, Michelle Monje, Éva Mracskó, Agnès Nadjar, Jonas J. Neher, Urtė Neniškytė, Harald Neumann, Mami Noda, Bo Peng, Francesca Peri, V. Hugh Perry, Phillip G. Popovich, Clare Pridans, Josef Priller, Marco Prinz, Davide Ragozzino, Richard M. Ransohoff, Michael W. Salter, Anne Schaefer, Dorothy P. Schafer, Michal Schwartz, Mikael Simons, Cody J. Smith, Wolfgang J. Streit, Tuan Leng Tay, Li‐Huei Tsai, Alexei Verkhratsky, Rommy von Bernhardi, Hiroaki Wake, Valérie Wittamer, Susanne A. Wolf, Long‐Jun Wu, Tony Wyss‐Coray - Neuron 2022 被引用: 1,880

  2. The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

    著者: Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O’Loughlin, Yang Xu, Zain Fanek, David Greco, Scott Smith, George Tweet, Zachary Humulock, Tobias Zrzavy, Patricia Conde-Sanroman, Mar Gacias, Zhiping Weng, Hao Chen, Emily Tjon, Fargol Mazaheri, Kristin Hartmann, Asaf Madi, Jason D. Ulrich, Markus Glatzel, Anna Worthmann, Jöerg Heeren, Bogdan Budnik, Cynthia A. Lemere, Tsuneya Ikezu, Frank L. Heppner, Vladimir Litvak, David M. Holtzman, Hans Lassmann, Howard L. Weiner, Jordi Ochando, Christian Haass, Oleg Butovsky - Immunity 2017 被引用: 3,049

  3. DNA methylation-based classification of central nervous system tumours

    著者: David Capper, David Jones, Martin Sill, Volker Hovestadt, Daniel Schrimpf, Dominik Sturm, Christian Koelsche, Felix Sahm, Lukas Chávez, David Reuß, Annekathrin Kratz, Annika K. Wefers, Kristin Huang, Kristian W. Pajtler, Leonille Schweizer, Damian Stichel, Adriana Olar, Nils W. Engel, Kerstin Lindenberg, Patrick N. Harter, Anne K. Braczynski, Karl H. Plate, Hildegard Dohmen, Boyan K. Garvalov, Roland Coras, Annett Hölsken, Ekkehard Hewer, Melanie Bewerunge‐Hudler, Matthias Schick, Roger Fischer, Rudi Beschorner, Jens Schittenhelm, Ori Staszewski, Khalida Wani, Pascale Varlet, Mélanie Pagès, Petra Temming, Dietmar Lohmann, Florian Selt, Hendrik Witt, Till Milde, Olaf Witt, Eleonora Aronica, Felice Giangaspero, Elisabeth J. Rushing, Wolfram Scheurlen, Christoph Geisenberger, Fausto J. Rodríguez, Albert J. Becker, Matthias Preusser, Christine Haberler, Rolf Bjerkvig, Jane Cryan, Michael A. Farrell, Martina Deckert, Jürgen Hench, Stephan Frank, Jonathan Serrano, Kasthuri Kannan, Aristotelis Tsirigos, Wolfgang Brück, Silvia Höfer, Stefanie Brehmer, Marcel Seiz‐Rosenhagen, Daniel Hänggi, Volkmar Hans, Stephanie Rozsnoki, Jordan R. Hansford, Patricia Kohlhof, Bjarne Winther Kristensen, Matt Lechner, Beatriz Lopes, Christian Mawrin, Ralf Ketter, Andreas E. Kulozik, Ziad Khatib, Frank L. Heppner, Arend Koch, Anne Jouvet, Catherine Keohane, Helmut Mühleisen, Wolf Mueller, Ute Pohl, Marco Prinz, Axel Benner, Marc Zapatka, Nicholas G. Gottardo, Pablo Hernáiz Driever, Christof M. Kramm, Hermann L. Müller, Stefan Rutkowski, Katja von Hoff, Michael C. Frühwald, Astrid Gnekow, Gudrun Fleischhack, Stephan Tippelt, Gabriele Calaminus, Camelia‐Maria Monoranu, Arie Perry, Chris Jones ほか 43 名 - Nature, Nat. 2018 被引用: 3,197

  4. High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

    著者: Dunja Mrdjen, Anto Pavlovic, Felix J. Hartmann, Bettina Schreiner, Sebastian G. Utz, Brian Leung, Iva Lelios, Frank L. Heppner, Jonathan Kipnis, Doron Merkler, Melanie Greter, Burkhard Becher - Immunity 2018 被引用: 1,025

  5. Immune attack: the role of inflammation in Alzheimer disease

    著者: Frank L. Heppner, Richard M. Ransohoff, Burkhard Becher - Nature reviews. Neuroscience 2015 被引用: 2,115

  6. Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

    著者: Jenny Meinhardt, Josefine Radke, Carsten Dittmayer, Jonas Franz, Carolina Thomas, Ronja Mothes, Michael Laue, Julia Schneider, Sebastian Brünink, Selina Greuel, Malte Lehmann, Olga Hassan, Tom Aschman, Elisa Schumann, Robert Lorenz Chua, Christian Conrad, Roland Eils, Werner Stenzel, Marc Windgassen, Larissa Rößler, Hans‐Hilmar Goebel, Hans R. Gelderblom, Hubert Martin, Andreas Nitsche, Walter Schulz‐Schaeffer, Samy Hakroush, Martin Sebastian Winkler, Björn Tampe, Franziska Scheibe, Péter Körtvelyessy, Dirk Reinhold, Britta Siegmund, Anja A. Kühl, Sefer Elezkurtaj, David Horst, Lars Oesterhelweg, Michael Tsokos, Barbara Ingold‐Heppner, Christine Stadelmann, Christian Drosten, Victor M. Corman, Helena Radbruch, Frank L. Heppner - Nature Neuroscience 2020 被引用: 1,497

  7. SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

    著者: Daniel Wendisch, Oliver Dietrich, Tommaso Mari, Saskia von Stillfried, Ignacio L. Ibarra, Mirja Mittermaier, Christin Mache, Robert Lorenz Chua, Rainer Knoll, Sara Timm, Sophia Brumhard, Tobias Krammer, Henrik Zauber, Anna Hiller, Anna Pascual Reguant, Ronja Mothes, Roman D. Bülow, Jessica Schulze, Alexander M. Leipold, Sonja Djudjaj, Florian Erhard, Robert Geffers, Fabian Pott, Julia Kazmierski, Josefine Radke, Panagiotis Pergantis, Kevin Baßler, Claudia Conrad, Anna C. Aschenbrenner, Birgit Sawitzki, Markus Landthaler, Emanuel Wyler, David Horst, Stefan Hippenstiel, Andreas C. Hocke, Frank L. Heppner, Alexander Uhrig, Carmen García, Felix Machleidt, Susanne Herold, Sefer Elezkurtaj, Charlotte Thibeault, Martin Witzenrath, Clément Cochain, Norbert Suttorp, Christian Drosten, Christine Goffinet, Florian Kurth, Joachim L. Schultze, Helena Radbruch, Matthias Ochs, Roland Eils, Holger Müller-Redetzky, Anja E. Hauser, Malte D. Luecken, Fabian J. Theis, Christian Conrad, Thorsten Wolff, Peter Boor, Matthias Selbach, Antoine‐Emmanuel Saliba, Leif Erik Sander - Cell 2021 被引用: 552

  8. A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration

    著者: Thorsten Buch, Frank L. Heppner, Christine Tertilt, Tobias Heinen, Marcel Kremer, F. Thomas Wunderlich, Steffen Jung, Ari Waisman - Nature Methods 2005 被引用: 935

  9. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration

    著者: Sabrina Lehmann, Christina Krüger, Boyoun Park, Katja Derkow, Karen Rosenberger, Jan Baumgart, Thorsten Trimbuch, Gina D. Eom, M. Hinz, David Kaul, Piet Habbel, Roland E. Kälin, Eleonora Franzoni, Agnieszka Rybak‐Wolf, Duong Thi Nguyen, Rüdiger W. Veh, Olaf Ninnemann, Oliver Peters, Robert Nitsch, Frank L. Heppner, Douglas T. Golenbock, Eckart Schott, Hidde L. Ploegh, F. Gregory Wulczyn, Seija Lehnardt - Nature Neuroscience 2012 被引用: 783

  10. Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model

    著者: Kiara Freitag, Nele Sterczyk, Sarah Wendlinger, Benedikt Obermayer, J Schulz, Vadim Farztdinov, Michael Mülleder, Markus Ralser, Judith Houtman, Lara Fleck, Caroline Braeuning, Roberto Sansevrino, Christian Hoffmann, Dragomir Milovanović, Stephan J. Sigrist, Thomas Conrad, Dieter Beule, Frank L. Heppner, Marina Jendrach - Journal of Neuroinflammation 2022 被引用: 105

  11. Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps

    著者: Borko Amulic, Sebastian Lorenz Knackstedt, Ulrike Abu Abed, Nikolaus Deigendesch, Christopher J. Harbort, Brian E. Caffrey, Volker Brinkmann, Frank L. Heppner, Philip W. Hinds, Arturo Zychlinsky - Developmental Cell 2017 被引用: 275

  12. SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals

    著者: Nils C. Gassen, Jan Papies, Thomas Bajaj, Jackson Emanuel, Frederik Dethloff, Robert Lorenz Chua, Jakob Trimpert, Nicolas Heinemann, Christine Niemeyer, Friderike Weege, Katja Hönzke, Tom Aschman, Daniel E. Heinz, Katja Weckmann, Tim Ebert, Andreas Zellner, Martina Lennarz, Emanuel Wyler, Simon Schroeder, Anja Richter, Daniela Niemeyer, Karen Hoffmann, Thomas F. Meyer, Frank L. Heppner, Victor M. Corman, Markus Landthaler, Andreas C. Hocke, Markus Morkel, Nikolaus Osterrieder, Christian Conrad, Roland Eils, Helena Radbruch, Patrick Giavalisco, Christian Drosten, Marcel A. Müller - Nature Communications 2021 被引用: 293

  13. Treatment of a genetic brain disease by CNS-wide microglia replacement

    著者: Yohei Shibuya, Kevin K. Kumar, Marius Marc-Daniel Mader, Yongjin Yoo, L Angel Ayala, Mu Zhou, Manuel Mohr, Gernot Neumayer, Ishan Kumar, Ryō Yamamoto, Paul Marcoux, Benjamin Liou, F. Chris Bennett, Hiromitsu Nakauchi, Ying Sun, Xiaoke Chen, Frank L. Heppner, Tony Wyss‐Coray, Thomas C. Südhof, Marius Wernig - Science Translational Medicine 2022 被引用: 127

  14. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis

    著者: Melanie Greter, Frank L. Heppner, Maria P. Lemos, Bernhard Odermatt, Norbert Goebels, Terri M. Laufer, Randolph J. Noelle, Burkhard Becher - Nature Medicine 2005 被引用: 849

  15. Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

    著者: Grietje Krabbe, Annett Halle, Vitali Matyash, Jan Leo Rinnenthal, Gina D. Eom, Ulrike Bernhardt, Kelly R. Miller, Stefan Prokop, Helmut Kettenmann, Frank L. Heppner - PLoS ONE 2013 被引用: 479

  16. Beclin1‐driven autophagy modulates the inflammatory response of microglia via NLRP3

    著者: Judith Houtman, Kiara Freitag, Niclas Gimber, Jan Schmoranzer, Frank L. Heppner, Marina Jendrach - The EMBO Journal 2019 被引用: 212

  17. Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

    著者: Paul Dembny, Andrew G. Newman, Manvendra Singh, M. Hinz, Michal Szczepek, Christina Krüger, Róbert Adalbert, Omar Dzaye, Thorsten Trimbuch, Thomas Wallach, Gunnar Kleinau, Katja Derkow, Bernhard Clemens Richard, Carola G. Schipke, Claus Scheidereit, Harald Stachelscheid, Douglas T. Golenbock, Oliver Peters, Michael P. Coleman, Frank L. Heppner, Patrick Scheerer, Victor Tarabykin, Klemens Ruprecht, Zsuzsanna Izsvák, Jens Mayer, Seija Lehnardt - JCI Insight 2020 被引用: 133

  18. Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline

    著者: Johannes vom Berg, Stefan Prokop, Kelly R. Miller, Juliane Obst, Roland E. Kälin, Ileana Lopategui‐Cabezas, Anja Wegner, Florian Mair, Carola G. Schipke, Oliver Peters, York Winter, Burkhard Becher, Frank L. Heppner - Nature Medicine 2012 被引用: 416

  19. Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19

    著者: Josefine Radke, Jenny Meinhardt, Tom Aschman, Robert Lorenz Chua, Vadim Farztdinov, Soeren Lukassen, Foo Wei Ten, Ekaterina Friebel, Naveed Ishaque, Jonas Franz, Valerie Helena Huhle, Ronja Mothes, Kristin Peters, Carolina Thomas, Shirin Schneeberger, Elisa Schumann, Leona Kawelke, Julia Jünger, Viktor Horst, Simon Streit, Regina von Manitius, Péter Körtvelyessy, Stefan Vielhaber, Dirk Reinhold, Anja E. Hauser, Anja Osterloh, Philipp Enghard, Jana Ihlow, Sefer Elezkurtaj, David Horst, Florian Kurth, Marcel A. Müller, Nils C. Gassen, Julia Melchert, Katharina Jechow, Bernd Timmermann, Camila Fernández‐Zapata, Chotima Böttcher, Werner Stenzel, Elke Krüger, Markus Landthaler, Emanuel Wyler, Victor M. Corman, Christine Stadelmann, Markus Ralser, Roland Eils, Frank L. Heppner, Michael Mülleder, Christian Conrad, Helena Radbruch - Nature Neuroscience 2024 被引用: 67

  20. Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors

    著者: Susan Brandenburg, Annett Müller, Kati Turkowski, Yordan T. Radev, Sergej Rot, Christin Schmidt, Alexander D. Bungert, Güliz Acker, Anne Schorr, Andreas Hippe, Kelly Miller, Frank L. Heppner, Bernhard Homey, Peter Vajkoczy - Acta Neuropathologica 2015 被引用: 236

  21. Robust methylation‐based classification of brain tumours using nanopore sequencing

    著者: Luis P. Kuschel, Jürgen Hench, Stephan Frank, Ivana Bratić Hench, Elodie Girard, Maud Blanluet, Julien Masliah‐Planchon, Martin Misch, Julia Onken, Marcus Czabanka, Dongsheng Yuan, Soeren Lukassen, Philipp Karau, Naveed Ishaque, Elisabeth G. Hain, Frank L. Heppner, Ahmed Idbaïh, Nikolaus Behr, Christoph Harms, David Capper, Philipp Euskirchen - Neuropathology and Applied Neurobiology 2022 被引用: 75

  22. Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

    著者: D. Marković, Katyayni Vinnakota, Sridhar Reddy Chirasani, Michael Synowitz, H. Raguet, Kristin Stock, Marcin Sliwa, S. Lehmann, Roland E. Kälin, Nico van Rooijen, Kenn Holmbeck, Frank L. Heppner, Juergen Kiwit, V. Matyash, Seija Lehnardt, Bożena Kamińska, R. Glass, Helmut Kettenmann - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 被引用: 387

  23. High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia

    著者: Caroline Baufeld, Anja Osterloh, Stefan Prokop, Kelly R. Miller, Frank L. Heppner - Acta Neuropathologica 2016 被引用: 230

  24. IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice

    著者: Myrto Andreadou, Florian Ingelfinger, Donatella De Feo, Teresa L M Cramer, Selma Tuzlak, Ekaterina Friebel, Bettina Schreiner, Pascale Eede, Shirin Schneeberger, Maria Geesdorf, Frederike Ridder, Christina A. Welsh, Laura Power, Daniel S. Kirschenbaum, Shiva K. Tyagarajan, Melanie Greter, Frank L. Heppner, Sarah Mundt, Burkhard Becher - Nature Neuroscience 2023 被引用: 45