Gottfried Otting
1986–2025 年に発表
- 123
- 論文数
- 18,087
- 被引用数
- 82
- h 指数
- 116
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology57.1%
- Medicine13.1%
- Chemistry6.3%
- Materials Science4.9%
- Immunology and Microbiology4%
- Neuroscience3.4%
- その他11.2%
トピック
- Protein Structure and Dynamics7.7%
- RNA and protein synthesis mechanisms4%
- Enzyme Structure and Function4%
- Advanced NMR Techniques and Applications3.4%
- Electron Spin Resonance Studies2.5%
- Developmental Biology and Gene Regulation2.2%
- その他76.2%
共著者
- Thomas Huber29
- Kurt Wüthrich22
- Edvards Liepinsh16
- Elwy H. Abdelkader16
- Nicholas E. Dixon13
- Christoph Nitsche12
- Kiyoshi Ozawa11
- Xun‐Cheng Su11
- Colin J. Jackson10
- Haocheng Qianzhu10
- Daniella Goldfarb8
- Guido Pintacuda8
- Yan Qian8
- Yi Tan8
- Martin Billeter7
- Martin Müller7
- Ansis Maļeckis6
- Bim Graham6
- Hiromasa Yagi6
- Kurt Wuethrich6
- Rebecca L. Frkic6
- Markus Affolter5
- Mithun C. Mahawaththa5
- Ah Young Park4
全論文
- Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir
著者: Sven Ullrich, Kasuni B. Ekanayake, Gottfried Otting, Christoph Nitsche - Bioorganic & Medicinal Chemistry Letters 2022 被引用: 198
- Site-Specific Incorporation of 7-Fluoro-L-tryptophan into Proteins by Genetic Encoding to Monitor Ligand Binding by 19F NMR Spectroscopy
著者: Haocheng Qianzhu, Elwy H. Abdelkader, Iresha D. Herath, Gottfried Otting, Thomas Huber - ACS Sensors 2022 被引用: 40
- Antiviral cyclic peptides targeting the main protease of SARS-CoV-2
著者: Jason Johansen‐Leete, Sven Ullrich, Sarah E. Fry, Rebecca L. Frkic, Max J. Bedding, Anupriya Aggarwal, Anneliese S. Ashhurst, Kasuni B. Ekanayake, Mithun C. Mahawaththa, Vishnu Mini Sasi, Stephanie Luedtke, Daniel Ford, Anthony J. O’Donoghue, Toby Passioura, Mark Larance, Gottfried Otting, Stuart Turville, Colin J. Jackson, Christoph Nitsche, Richard J. Payne - Chemical Science 2022 被引用: 64
- Paramagnetic Chemical Probes for Studying Biological Macromolecules
著者: Qing Miao, Christoph Nitsche, Henry W. Orton, Mark Overhand, Gottfried Otting, Marcellus Ubbink - Chemical Reviews 2022 被引用: 112
- Through-Space Scalar 19F–19F Couplings between Fluorinated Noncanonical Amino Acids for the Detection of Specific Contacts in Proteins
著者: Henry W. Orton, Haocheng Qianzhu, Elwy H. Abdelkader, Edan Habel, Yi Tan, Rebecca L. Frkic, Colin J. Jackson, Thomas Huber, Gottfried Otting - Journal of the American Chemical Society 2021 被引用: 45
- Genetic Encoding of Cyanopyridylalanine for In‐Cell Protein Macrocyclization by the Nitrile–Aminothiol Click Reaction
著者: Elwy H. Abdelkader, Haocheng Qianzhu, Josemon George, Rebecca L. Frkic, Colin J. Jackson, Christoph Nitsche, Gottfried Otting, Thomas Huber - Angewandte Chemie International Edition 2022 被引用: 43
- Genetic Encoding of Fluoro-l-tryptophans for Site-Specific Detection of Conformational Heterogeneity in Proteins by NMR Spectroscopy
著者: Haocheng Qianzhu, Elwy H. Abdelkader, Gottfried Otting, Thomas Huber - Journal of the American Chemical Society 2024 被引用: 39
- Genetic Encoding of para-Pentafluorosulfanyl Phenylalanine: A Highly Hydrophobic and Strongly Electronegative Group for Stable Protein Interactions
著者: Haocheng Qianzhu, Adarshi P. Welegedara, Holly Williamson, Amy E. McGrath, Mithun C. Mahawaththa, Nicholas E. Dixon, Gottfried Otting, Thomas Huber - Journal of the American Chemical Society 2020 被引用: 45
- Improving a Natural Enzyme Activity through Incorporation of Unnatural Amino Acids
著者: Isaac N. Ugwumba, Kiyoshi Ozawa, Zhi‐Qiang Xu, Fernanda Ely, Jee Loon Foo, Anthony J. Herlt, Chris W. Coppin, Sue Brown, Matthew C. Taylor, David L. Ollis, Lewis N. Mander, Gerhard Schenk, Nicholas E. Dixon, Gottfried Otting, John G. Oakeshott, Colin J. Jackson - Journal of the American Chemical Society 2010 被引用: 101
- Short-range ENDOR distance measurements between Gd(iii) and trifluoromethyl labels in proteins
著者: Martyna Judd, Elwy H. Abdelkader, Mian Qi, Jeffrey R. Harmer, Thomas Huber, Adelheid Godt, Anton Savitsky, Gottfried Otting, Nicholas J. Cox - Physical Chemistry Chemical Physics 2022 被引用: 33
- Genetic Encoding of N 6 -(((Trimethylsilyl)methoxy)carbonyl)- l -lysine for NMR Studies of Protein–Protein and Protein–Ligand Interactions
著者: Elwy H. Abdelkader, Haocheng Qianzhu, Yi Tan, Luke A. Adams, Thomas Huber, Gottfried Otting - Journal of the American Chemical Society 2021 被引用: 38
- Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5′-Difluoroleucine in a Protein
著者: Rebecca L. Frkic, Yi Tan, Elwy H. Abdelkader, Ansis Maļeckis, E. Târcoveanu, Christoph Nitsche, Gottfried Otting, Colin J. Jackson - Biochemistry 2024 被引用: 16
- (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5′-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect
著者: Yi Tan, Elwy H. Abdelkader, E. Târcoveanu, Ansis Maļeckis, Christoph Nitsche, Gottfried Otting - Biochemistry 2024 被引用: 16
- Homeodomain-DNA recognition
著者: Walter J. Gehring, Yan Qian, Martin Billeter, Katsuo Furukubo-Tokunaga, Alexander F. Schier, Diana Reséndez‐Pérez, Markus Affolter, Gottfried Otting, Kurt Wüthrich - Cell 1994 被引用: 795
- Proton exchange rates from amino acid side chains— implications for image contrast
著者: Edvards Liepinsh, Gottfried Otting - Magnetic Resonance in Medicine 1996 被引用: 332
- Pseudocontact shifts in biomolecular NMR using paramagnetic metal tags
著者: Christoph Nitsche, Gottfried Otting - Progress in Nuclear Magnetic Resonance Spectroscopy 2016 被引用: 168
- Biocompatible Macrocyclization between Cysteine and 2-Cyanopyridine Generates Stable Peptide Inhibitors
著者: Christoph Nitsche, Hideki Onagi, Jun Ping Quek, Gottfried Otting, Dahai Luo, Thomas Huber - Organic Letters 2019 被引用: 72
- Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme
著者: Joe A. Kaczmarski, Mithun C. Mahawaththa, Akiva Feintuch, Ben E. Clifton, Luke A. Adams, Daniella Goldfarb, Gottfried Otting, Colin J. Jackson - Nature Communications 2020 被引用: 67
- Clean TOCSY for proton spin system identification in macromolecules
著者: C Griesinger, Gottfried Otting, Kurt Wuethrich, Richard R. Ernst - Journal of the American Chemical Society 1988 被引用: 1,139
- The structure of the homeodomain and its functional implications
著者: W J Gehring, Martin Müller, Markus Affolter, Anthony Percival‐Smith, Martin Billeter, Yan Qian, Gottfried Otting, Kurt Wüthrich - Trends in Genetics 1990 被引用: 239
- De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease
著者: Christoph Nitsche, Toby Passioura, Paul Varava, Mithun C. Mahawaththa, Mila M. Leuthold, Christian D. Klein, Hiroaki Suga, Gottfried Otting - ACS Medicinal Chemistry Letters 2019 被引用: 74
- NT*-HRV3CP: An optimized construct of human rhinovirus 14 3C protease for high-yield expression and fast affinity-tag cleavage
著者: Elwy H. Abdelkader, Gottfried Otting - Journal of Biotechnology 2020 被引用: 38
- Protein Hydration in Aqueous Solution
著者: Gottfried Otting, Edvards Liepinsh, Kurt Wüthrich - Science 1991 被引用: 789
- Identification of Protein Surfaces by NMR Measurements with a Paramagnetic Gd(III) Chelate
著者: Guido Pintacuda, Gottfried Otting - Journal of the American Chemical Society 2001 被引用: 216
