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Hakon Leffler

1979–2025 年に発表

121
論文数
19,857
被引用数
84
h 指数
118
i10 指数

被引用数

Hakon Leffler の年別被引用数1936 年: 被引用 2 件1978 年: 被引用 1 件1980 年: 被引用 2 件1981 年: 被引用 12 件1982 年: 被引用 16 件1983 年: 被引用 25 件1984 年: 被引用 26 件1985 年: 被引用 33 件1986 年: 被引用 39 件1987 年: 被引用 65 件1988 年: 被引用 45 件1989 年: 被引用 31 件1990 年: 被引用 36 件1991 年: 被引用 60 件1992 年: 被引用 44 件1993 年: 被引用 63 件1994 年: 被引用 68 件1995 年: 被引用 116 件1996 年: 被引用 91 件1997 年: 被引用 141 件1998 年: 被引用 143 件1999 年: 被引用 135 件2000 年: 被引用 156 件2001 年: 被引用 156 件2002 年: 被引用 229 件2003 年: 被引用 142 件2004 年: 被引用 153 件2005 年: 被引用 184 件2006 年: 被引用 127 件2007 年: 被引用 137 件2008 年: 被引用 170 件2009 年: 被引用 158 件2010 年: 被引用 161 件2011 年: 被引用 135 件2012 年: 被引用 120 件2013 年: 被引用 93 件2014 年: 被引用 128 件2015 年: 被引用 100 件2016 年: 被引用 160 件2017 年: 被引用 114 件2018 年: 被引用 164 件2019 年: 被引用 477 件2020 年: 被引用 547 件2021 年: 被引用 496 件2022 年: 被引用 383 件2023 年: 被引用 384 件2024 年: 被引用 540 件2025 年: 被引用 225 件2026 年: 被引用 6 件1937〜1977 年は被引用が無いため表示していません1979 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 1,435 件、この内訳の 26.9%中国: 引用元論文 434 件、この内訳の 8.1%スウェーデン: 引用元論文 358 件、この内訳の 6.7%ドイツ: 引用元論文 338 件、この内訳の 6.3%イギリス: 引用元論文 311 件、この内訳の 5.8%日本: 引用元論文 280 件、この内訳の 5.3%フランス: 引用元論文 208 件、この内訳の 3.9%カナダ: 引用元論文 159 件、この内訳の 3%オランダ: 引用元論文 158 件、この内訳の 3%イタリア: 引用元論文 138 件、この内訳の 2.6%スペイン: 引用元論文 130 件、この内訳の 2.4%デンマーク: 引用元論文 114 件、この内訳の 2.1%
0%26.9%その他 23.9%

機関

分野

  • Immunology and Microbiology40.8%
  • Biochemistry, Genetics and Molecular Biology25.9%
  • Medicine22.4%
  • Neuroscience3.5%
  • Chemistry1.5%
  • Agricultural and Biological Sciences1.4%
  • その他4.5%

トピック

  • Galectins and Cancer Biology14.3%
  • Glycosylation and Glycoproteins Research9.1%
  • Signaling Pathways in Disease3.9%
  • Toxin Mechanisms and Immunotoxins2.9%
  • Peptidase Inhibition and Analysis2.2%
  • Escherichia coli research studies2.2%
  • その他65.4%

共著者

全論文

検索で開く
  1. Galectins at a glance

    著者: Ludger Johannes, Ralf Jacob, Hakon Leffler - Journal of Cell Science 2018 被引用: 613

  2. Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

    著者: Antonio Boza‐Serrano, Rocío Ruiz, Raquel Sánchez‐Varo, Juan García‐Revilla, Yiyi Yang, Itzia Jiménez-Ferrer, Agnes Paulus, Malin Wennström, Anna Vilalta, David H. Allendorf, José Carlos Dávila, John Stegmayr, Sebastián Jiménez, María Angustias Roca-Ceballos, Victoria Navarro, Maria Swanberg, Christine L. Hsieh, Luís Miguel Real, Elisabet Englund, Sara Linse, Hakon Leffler, Ulf J. Nilsson, Guy C. Brown, Antonia Gutiérrez, Javier Vitórica, José L. Venero, Tomas Deierborg - Acta Neuropathologica 2019 被引用: 370

  3. Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis

    著者: Nikhil Hirani, Alison C. MacKinnon, Lisa Nicol, Paul Ford, Hans Schambye, Anders N. Pedersen, Ulf J. Nilsson, Hakon Leffler, Tariq Sethi, Susan Tantawi, Lise Gravelle, Robert J. Slack, Ross Mills, Utsa Karmakar, Duncan C. Humphries, Fredrik R. Zetterberg, Lucy Keeling, Lyn Paul, Philip L. Molyneaux, Feng Li, Wendy Funston, Ian Forrest, A. John Simpson, Michael Gibbons, Toby M. Maher - European Respiratory Journal 2020 被引用: 219

  4. Galectin-3, a marker for vacuole lysis by invasive pathogens

    著者: Irit Paz, Martin Sachse, Nicolas Dupont, Joëlle Mounier, Cecilia Cederfur, Jost Enninga, Hakon Leffler, Françoise Poirier, Marie‐Christine Prévost, Frank Lafont, Philippe Sansonetti - Cellular Microbiology 2009 被引用: 383

  5. Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3

    著者: Alison C. MacKinnon, Michael Gibbons, Sarah L. Farnworth, Hakon Leffler, Ulf J. Nilsson, Tamara Delaine, A. John Simpson, Stuart J. Forbes, Nik Hirani, Jack Gauldie, Tariq Sethi - American Journal of Respiratory and Critical Care Medicine 2011 被引用: 521

  6. Galectins: A family of animal β-galactoside-binding lectins

    著者: Samuel H. Barondes, Vincent Castronovo, Douglas N.W. Cooper, Richard D. Cummings, Kurt Drickamer, Ten Felzi, Michael A. Gitt, Jun Hirabayashi, Colin Hughes, Ken-ichi Kasai, Hakon Leffler, Fu‐Tong Liu, Reuben Lotan, Arthur M. Mercurio, Michel Monsigny, Shiv Pillai, Françoise Poirer, Avraham Raz, Peter Rigby, James M. Rini, John L. Wang - Cell 1994 被引用: 1,207

  7. Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation

    著者: Miguel Ángel Burguillos, Martina Svensson, Tim Schulte, Antonio Boza‐Serrano, Albert García-Quintanilla, Edel Kavanagh, Martiniano Santiago, Nikenza Viceconte, Maria José Oliva-Martín, Ahmed M. Osman, Emma Salomonsson, Lahouari Amar, Annette Persson, Klas Blomgren, Adnane Achour, Elisabet Englund, Hakon Leffler, José L. Venero, Bertrand Joseph, Tomas Deierborg - Cell Reports 2015 被引用: 357

  8. Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease

    著者: Fredrik R. Zetterberg, Alison C. MacKinnon, Thomas Brimert, Lise Gravelle, Richard Johnsson, Barbro Kahl-Knutson, Hakon Leffler, Ulf J. Nilsson, Anders N. Pedersen, Kristoffer Peterson, James A. Roper, Hans Schambye, Robert J. Slack, Susan Tantawi - Journal of Medicinal Chemistry 2022 被引用: 92

  9. Galectins. Structure and function of a large family of animal lectins.

    著者: S H Barondes, D.N. Cooper, Michael A. Gitt, Hakon Leffler - Journal of Biological Chemistry 1994 被引用: 1,496

  10. An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade

    著者: Lynda Vuong, Eleni Kouverianou, Claire Rooney, Brian J. McHugh, Sarah Howie, Christopher D. Gregory, Stuart J. Forbes, Neil C. Henderson, Fredrik R. Zetterberg, Ulf J. Nilsson, Hakon Leffler, Paul Ford, Anders N. Pedersen, Lise Gravelle, Susan Tantawi, Hans Schambye, Tariq Sethi, Alison C. MacKinnon - Cancer Research 2019 被引用: 141

  11. Interplay between Conformational Entropy and Solvation Entropy in Protein–Ligand Binding

    著者: Maria Luisa Verteramo, Olof Stenström, Majda Misini Ignjatović, Octav Caldararu, Martin Olsson, Francesco Manzoni, Hakon Leffler, Esko Oksanen, Derek T. Logan, Ulf J. Nilsson, Ulf Ryde, Mikael Akke - Journal of the American Chemical Society 2019 被引用: 138

  12. X-ray Crystal Structure of the Human Galectin-3 Carbohydrate Recognition Domain at 2.1-Å Resolution

    著者: J. Seetharaman, A. I. Kanigsberg, Rita Slaaby, Hakon Leffler, Samuel H. Barondes, James M. Rini - Journal of Biological Chemistry 1998 被引用: 422

  13. Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor: a single- and multiple-dose first-in-human study in healthy participants

    著者: Vassilios Aslanis, Robert J. Slack, Alison C. MacKinnon, C McClinton, Susan Tantawi, Lise Gravelle, Ulf J. Nilsson, Hakon Leffler, Ashley Brooks, Sanjeev Khindri, Richard P. Marshall, Anders N. Pedersen, Hans Schambye, Fredrik R. Zetterberg - Cancer Chemotherapy and Pharmacology 2023 被引用: 40

  14. Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens

    著者: Sean R. Stowell, Connie M. Arthur, Padmaja Mehta, Kristen A. Slanina, Ola Blixt, Hakon Leffler, David F. Smith, Richard D. Cummings - Journal of Biological Chemistry 2008 被引用: 417

  15. The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

    著者: K. Saraboji, M. Håkansson, Samuel Genheden, Carl Diehl, Johan �Qvist, Ulrich Weininger, Ulf J. Nilsson, Hakon Leffler, Ulf Ryde, Mikael Akke, Derek T. Logan - Biochemistry 2011 被引用: 162

  16. Ligand Induced Galectin-3 Protein Self-association

    著者: Adriana Lepur, Emma Salomonsson, Ulf J. Nilsson, Hakon Leffler - Journal of Biological Chemistry 2012 被引用: 161

  17. Monosaccharide Derivatives with Low‐Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine–Amide, Phenyl–Arginine, Sulfur–π, and Halogen Bond Interactions

    著者: Fredrik R. Zetterberg, Kristoffer Peterson, Richard Johnsson, Thomas Brimert, M. Håkansson, Derek T. Logan, Hakon Leffler, Ulf J. Nilsson - ChemMedChem 2017 被引用: 106

  18. Extracellular and intracellular small-molecule galectin-3 inhibitors

    著者: John Stegmayr, Fredrik R. Zetterberg, Michael C. Carlsson, Xiaoli Huang, Gunjan Sharma, Barbro Kahl-Knutson, Hans Schambye, Ulf J. Nilsson, Stina Oredsson, Hakon Leffler - Scientific Reports 2019 被引用: 105

  19. Galectin-9 Signaling Drives Breast Cancer Invasion through Extracellular Matrix

    著者: Dharma Pally, Mallar Banerjee, Shahid Hussain, Rekha V. Kumar, Alexandra Petersson, Ebba Rosendal, Ludvig Gunnarsson, Kristoffer Peterson, Hakon Leffler, Ulf J. Nilsson, Ramray Bhat - ACS Chemical Biology 2022 被引用: 31

  20. Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

    著者: Kristoffer Peterson, Rohit Kumar, Olof Stenström, Priya Ranjan Prasad Verma, Prashant R. Verma, M. Håkansson, Barbro Kahl‐Knutsson, Fredrik R. Zetterberg, Hakon Leffler, Mikael Akke, Derek T. Logan, Ulf J. Nilsson - Journal of Medicinal Chemistry 2017 被引用: 99

  21. Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C

    著者: Johan Wallerstein, Vilhelm Ekberg, Majda Misini Ignjatović, Rohit Kumar, Octav Caldararu, Kristoffer Peterson, Sven Wernersson, Ulrika Brath, Hakon Leffler, Esko Oksanen, Derek T. Logan, Ulf J. Nilsson, Ulf Ryde, Mikael Akke - JACS Au 2021 被引用: 52

  22. Galectin‐3‐Binding Glycomimetics that Strongly Reduce Bleomycin‐Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

    著者: Tamara Delaine, P.M. Collins, Alison C. MacKinnon, Gunjan Sharma, John Stegmayr, Vishal Kumar Rajput, Santanu Mandal, Ian Cumpstey, A. Larumbe, Bader A. Salameh, Barbro Kahl‐Knutsson, Hilde van Hattum, Monique van Scherpenzeel, Roland J. Pieters, Tariq Sethi, Hans Schambye, Stina Oredsson, Hakon Leffler, Helen Blanchard, Ulf J. Nilsson - ChemBioChem 2016 被引用: 198

  23. 1H-1,2,3-Triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors

    著者: Bader A. Salameh, Ian Cumpstey, Anders Sundin, Hakon Leffler, Ulf J. Nilsson - Bioorganic & Medicinal Chemistry 2010 被引用: 114

  24. Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression

    著者: Seok‐Jun Kim, Hyeok-Gu Kang, Kyungeun Kim, Hoyoung Kim, Fredrik R. Zetterberg, Young Soo Park, Hyun‐Soo Cho, Stephen M. Hewitt, Joon‐Yong Chung, Ulf J. Nilsson, Hakon Leffler, Kyung‐Hee Chun - Gastric Cancer 2021 被引用: 40