Harold Varmus
1969–2025 年に発表
- 212
- 論文数
- 73,977
- 被引用数
- 131
- h 指数
- 209
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology44.1%
- Medicine39%
- Immunology and Microbiology5.9%
- Agricultural and Biological Sciences2.3%
- Computer Science2.1%
- Neuroscience1.5%
- その他5.1%
トピック
- Lung Cancer Treatments and Mutations3.8%
- Wnt/β-catenin signaling in development and cancer3.1%
- Cancer Genomics and Diagnostics2.8%
- Cancer-related gene regulation2.2%
- Virus-based gene therapy research1.9%
- Cancer-related Molecular Pathways1.6%
- その他84.6%
共著者
- J. Michael Bishop55
- Don Ganem10
- Katerina Politi9
- Arthur D. Levinson7
- G M Ringold7
- Gregory M. Shackleford7
- Mario Chamorro7
- Peter R. Shank7
- Roel Nusse7
- Stephen H. Hughes7
- William Pao7
- Anthony M.C. Brown6
- John Majors6
- Maureen F. Zakowski6
- Nancy Quintrell6
- William W. Lockwood6
- Brian C. Lewis5
- Deborah H. Spector5
- Hermann Oppermann5
- Katrina Podsypanina5
- Manfred Schwab5
- Mark G. Kris5
- Patrick O. Brown5
- Ramareddy V. Guntaka5
全論文
- A New Initiative on Precision Medicine
著者: Francis S. Collins, Harold Varmus - New England Journal of Medicine 2015 被引用: 5,179
- Toward a Shared Vision for Cancer Genomic Data
著者: Robert L. Grossman, Allison P. Heath, Vincent Ferretti, Harold Varmus, Douglas R. Lowy, Warren A. Kibbe, Louis M. Staudt - New England Journal of Medicine 2016 被引用: 1,808
- Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
著者: Roel Nusse, Harold Varmus - Cell 1982 被引用: 1,855
- Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain
著者: William Pao, Vincent A. Miller, Katerina Politi, Gregory J. Riely, Romel Somwar, Maureen F. Zakowski, Mark G. Kris, Harold Varmus - PLoS Medicine 2005 被引用: 3,526
- Somatic mutations affect key pathways in lung adenocarcinoma
著者: Li Ding, Gad Getz, David A. Wheeler, Elaine R. Mardis, Michael D. McLellan, Kristian Cibulskis, Carrie Sougnez, Heidi Greulich, Donna M. Muzny, Margaret Morgan, Lucinda Fulton, Robert S. Fulton, Qunyuan Zhang, Michael C. Wendl, Michael S. Lawrence, David E. Larson, Ken Chen, David J. Dooling, Aniko Sabo, Alicia Hawes, Hua Shen, Shalini N. Jhangiani, Lora Lewis, Otis Hall, Yiming Zhu, Tittu Mathew, Yanru Ren, Jiqiang Yao, Steven E. Scherer, Kerstin Clerc, Ginger Metcalf, Brian Ng, Aleksandar Milosavljevic, Manuel L. Gonzalez‐Garay, John R. Osborne, Rick Meyer, Xiaoqi Shi, Yuzhu Tang, Daniel C. Koboldt, Ling Lin, Rachel M. Abbott, Tracie L. Miner, Craig Pohl, Ginger Fewell, Carrie A. Haipek, Heather K. Schmidt, Brian H. Dunford-Shore, Aldi T. Kraja, Seth D. Crosby, Christopher S. Sawyer, Tammi L. Vickery, Sacha N Sander, Jody S. Robinson, Wendy Winckler, Jennifer Baldwin, Lucian R. Chirieac, Amit Dutt, Tim Fennell, Megan Hanna, Bruce E. Johnson, Robert C. Onofrio, Roman K. Thomas, Giovanni Tonon, Barbara A. Weir, Xiao‐Jun Zhao, Liuda Ziaugra, Michael C. Zody, Thomas J. Giordano, Mark B. Orringer, Jack A. Roth, Margaret R. Spitz, Ignacio I. Wistuba, Bradley A. Ozenberger, Peter J. Good, Andrew C. Chang, David G. Beer, Mark A. Watson, Marc Ladanyi, Stephen Broderick, Akihiko Yoshizawa, William D. Travis, William Pao, Michael A. Province, George M. Weinstock, Harold Varmus, Stacey Gabriel, Eric S. Lander, Richard A. Gibbs, Matthew Meyerson, Richard K. Wilson - Nature 2008 被引用: 2,750
- EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib
著者: William Pao, Vincent A. Miller, Maureen F. Zakowski, Jennifer A. Doherty, Katerina Politi, Inderpal S. Sarkaria, Bhuvanesh Singh, Robert T. Heelan, Valerie W. Rusch, Lucinda A. Fulton, Elaine R. Mardis, Doris M. Kupfer, Richard K. Wilson, Mark G. Kris, Harold Varmus - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 被引用: 4,344
- Lineage-specific intolerance to oncogenic drivers restricts histological transformation
著者: Eric E. Gardner, Ethan M. Earlie, Kate Li, Jerin Thomas, Melissa J. Hubisz, Benjamin D. Stein, Chen Zhang, Lewis C. Cantley, Ashley M. Laughney, Harold Varmus - Science 2024 被引用: 91
- Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
著者: Garrett M. Brodeur, Robert C. Seeger, Manfred Schwab, Harold Varmus, J. Michael Bishop - Science 1984 被引用: 2,288
- Epstein-Barr Virus: An Important Vaccine Target for Cancer Prevention
著者: Jeffrey I. Cohen, Anthony S. Fauci, Harold Varmus, Gary J. Nabel - Science Translational Medicine 2011 被引用: 386
- KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib
著者: William Pao, Theresa Y. Wang, Gregory J. Riely, Vincent A. Miller, Qiulu Pan, Marc Ladanyi, Maureen F. Zakowski, Robert T. Heelan, Mark G. Kris, Harold Varmus - PLoS Medicine 2005 被引用: 1,525
- Rescuing US biomedical research from its systemic flaws
著者: Bruce Alberts, Marc W. Kirschner, Shirley M. Tilghman, Harold Varmus - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 被引用: 811
- Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy
著者: Jordi Barretina, Barry S. Taylor, Shantanu Banerji, Alexis Ramos, Mariana Lagos‐Quintana, Penelope DeCarolis, Kinjal Shah, Nicholas D. Socci, Barbara A. Weir, Alan L. Ho, Derek Y. Chiang, Boris Reva, Craig H. Mermel, Gad Getz, Yevgenyi Antipin, Rameen Beroukhim, John E. Major, Charles Hatton, Richard Nicoletti, Megan Hanna, Ted Sharpe, Tim Fennell, Kristian Cibulskis, Robert C. Onofrio, Tsuyoshi Saito, Neerav Shukla, Christopher Lau, Sven Nelander, Serena J. Silver, Carrie Sougnez, Agnès Viale, Wendy Winckler, Robert G. Maki, Levi A. Garraway, Alex Lash, Heidi Greulich, David E. Root, William R. Sellers, Gary K. Schwartz, Cristina R. Antonescu, Eric S. Lander, Harold Varmus, Marc Ladanyi, Chris Sander, Matthew Meyerson, Samuel Singer - Nature Genetics 2010 被引用: 726
- Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma
著者: Arun M. Unni, William W. Lockwood, Kreshnik Zejnullahu, Shih-Queen Lee-Lin, Harold Varmus - eLife 2015 被引用: 205
- Lung adenocarcinomas induced in mice by mutant EGF receptors foundin human lung cancers respondto a tyrosine kinase inhibitor orto down-regulation of the receptors
著者: Katerina Politi, Maureen F. Zakowski, Pang‐Dian Fan, Emily Schonfeld, William Pao, Harold Varmus - Genes & Development 2006 被引用: 486
- Mutational landscape of EGFR- , MYC- , and Kras- driven genetically engineered mouse models of lung adenocarcinoma
著者: David G. McFadden, Katerina Politi, Arjun Bhutkar, Frances K. Chen, Xiaoling Song, Mono Pirun, Philip M. Santiago, Caroline Kim-Kiselak, James T. Platt, Emily Lee, Emily Hodges, Adam P. Rosebrock, Roderick T. Bronson, Nicholas D. Socci, Gregory J. Hannon, Tyler Jacks, Harold Varmus - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 209
- DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
著者: D. Stéhelin, Harold Varmus, J. Michael Bishop, Peter K. Vogt - Nature 1976 被引用: 1,320
- Characterizing the cancer genome in lung adenocarcinoma
著者: Barbara A. Weir, Michele Sue‐Ann Woo, Gad Getz, Sven Perner, Li Ding, Rameen Beroukhim, William M. Lin, Michael A. Province, Aldi T. Kraja, Laura A. Johnson, Kinjal Shah, Mitsuo Sato, Roman K. Thomas, Justine A. Barletta, Ingrid B. Borecki, Stephen Broderick, Andrew C. Chang, Derek Y. Chiang, Lucian R. Chirieac, Jeonghee Cho, Yoshitaka Fujii, Adi F. Gazdar, Thomas J. Giordano, Heidi Greulich, Megan Hanna, Bruce E. Johnson, Mark G. Kris, Alex Lash, Ling Lin, Neal I. Lindeman, Elaine R. Mardis, John D. McPherson, John D. Minna, Margaret Morgan, Mark Nadel, Mark B. Orringer, John R. Osborne, Brad Ozenberger, Alex H. Ramos, James Robinson, Jack A. Roth, Valerie W. Rusch, Hidefumi Sasaki, Frances A. Shepherd, Carrie Sougnez, Margaret R. Spitz, Ming‐Sound Tsao, David Twomey, Roel G.W. Verhaak, George M. Weinstock, David A. Wheeler, Wendy Winckler, Akihiko Yoshizawa, Soyoung Yu, Maureen F. Zakowski, Qunyuan Zhang, David G. Beer, Ignacio I. Wistuba, Mark A. Watson, Levi A. Garraway, Marc Ladanyi, William D. Travis, William Pao, Mark A. Rubin, Stacey Gabriel, Richard A. Gibbs, Harold Varmus, Richard K. Wilson, Eric S. Lander, Matthew Meyerson - Nature 2007 被引用: 1,125
- Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines
著者: Romel Somwar, Hediye Erdjument‐Bromage, Erik Larsson, David Shum, William W. Lockwood, Guangli Yang, Chris Sander, Ouathek Ouerfelli, Paul Tempst, Hakim Djaballah, Harold Varmus - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 被引用: 159
- Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells
著者: Arun M. Unni, Bryant Harbourne, Min Hee Oh, Sophia A. Wild, John R. Ferrarone, William W. Lockwood, Harold Varmus - eLife 2018 被引用: 114
- Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells
著者: Huanhuan Joyce Chen, Asaf Poran, Arun M. Unni, Sarah X.L. Huang, Olivier Elemento, Hans‐Willem Snoeck, Harold Varmus - The Journal of Experimental Medicine 2019 被引用: 102
- Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
著者: Manfred Schwab, Kari Alitalo, Karl-Heinz Klempnauer, Harold Varmus, J. Michael Bishop, Fred Gilbert, Garrett M. Brodeur, Milton N. Goldstein, Jeffrey M. Trent - Nature 1983 被引用: 1,427
- Characterization of ribosomal frameshifting in HIV-1 gag-pol expression
著者: Tyler Jacks, Michael D. Power, Frank R. Masiarz, Paul A. Luciw, Philip J. Barr, Harold Varmus - Nature 1988 被引用: 951
- Three decades of Wnts: a personal perspective on how a scientific field developed
著者: Roel Nusse, Harold Varmus - The EMBO Journal 2012 被引用: 409
- Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP
著者: Feng Cong, Liang Schweizer, Harold Varmus - Development 2004 被引用: 352
