Hartmut Jaeschke
1982–2025 年に発表
- 231
- 論文数
- 40,941
- 被引用数
- 121
- h 指数
- 225
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine44.2%
- Biochemistry, Genetics and Molecular Biology20.1%
- Pharmacology, Toxicology and Pharmaceutics18.5%
- Immunology and Microbiology4.8%
- Engineering2.6%
- Agricultural and Biological Sciences1.7%
- その他8.1%
トピック
- Drug-Induced Hepatotoxicity and Protection8.4%
- Liver Disease Diagnosis and Treatment6.4%
- Liver physiology and pathology4.9%
- Liver Disease and Transplantation3.7%
- Drug Transport and Resistance Mechanisms3.6%
- Organ Transplantation Techniques and Outcomes2.8%
- その他70.2%
共著者
- Anup Ramachandran64
- Anwar Farhood41
- Mitchell R. McGill34
- Jephte Y. Akakpo23
- Wen‐Xing Ding21
- Mary Lynn Bajt18
- John J. Lemasters17
- Benjamin L. Woolbright15
- David S. Umbaugh15
- Hong‐Min Ni14
- Nga Nguyen12
- Steven C. Curry12
- C. David Williams11
- Michael A. Fisher11
- Yuchao Xie11
- Barry H. Rumack8
- C. Wayne Smith8
- Matthew R. Sharpe8
- Olamide B. Adelusi8
- Kuo Du7
- Margitta Lebofsky7
- Michael Trauner7
- Xiaojuan Chao7
- Jaspreet S. Gujral6
全論文
- The Multifaceted Therapeutic Role of N-Acetylcysteine (NAC) in Disorders Characterized by Oxidative Stress
著者: Ganesh Raghu, Michael Berk, Peter A. Campochiaro, Hartmut Jaeschke, Giancarlo Marenzi, Luca Richeldi, Fuqiang Wen, Ferdinando Nicoletti, Peter Calverley - Current Neuropharmacology 2020 被引用: 273
- Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential
著者: Kuo Du, Anup Ramachandran, Hartmut Jaeschke - Redox Biology 2016 被引用: 554
- Acetaminophen Hepatotoxicity: Paradigm for Understanding Mechanisms of Drug-Induced Liver Injury
著者: Hartmut Jaeschke, Anup Ramachandran - Annual Review of Pathology Mechanisms of Disease 2024 被引用: 209
- Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity
著者: Hartmut Jaeschke, Mitchell R. McGill, Anup Ramachandran - Drug Metabolism Reviews 2012 被引用: 943
- Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure
著者: Benjamin L. Woolbright, Hartmut Jaeschke - Journal of Hepatology 2016 被引用: 386
- Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
著者: Patrício Godoy, Nicola J. Hewitt, Ute Albrecht, Melvin E. Andersen, Nariman Ansari, Sudin Bhattacharya, Johannes G. Bode, Jennifer Bolleyn, Christoph Borner, J Böttger, Albert Braeuning, Robert A. Budinsky, Britta Burkhardt, Neil R. Cameron, Giovanni Camussi, Chong-Su Cho, Yun-Jaie Choi, J. Craig Rowlands, Uta Dahmen, Georg Damm, Olaf Dirsch, M. Teresa Donato, Jian Dong, Steven Dooley, Dirk Drasdo, Rowena Eakins, Karine Sá Ferreira, Valentina Fonsato, Joanna Fraczek, Rolf Gebhardt, Andrew Gibson, Matthias Glanemann, Christopher E. Goldring, Marı́a José Gómez-Lechón, Geny M. M. Groothuis, Lena Gustavsson, Christelle Guyot, David Hallifax, Seddik Hammad, Adam S. Hayward, Dieter Häussinger, Claus Hellerbrand, Philip Hewitt, Stefan Hoehme, Hermann−Georg Holzhütter, J. Brian Houston, Jens Hrach, Kiyomi Ito, Hartmut Jaeschke, Verena Keitel, Jens Kelm, B. Kevin Park, Claus Kordes, Gerd A. Kullak‐Ublick, Edward L. LeCluyse, Peng Lü, Jennifer L. Luebke-Wheeler, Anna Lutz, Daniel J. Maltman, Madlen Matz‐Soja, Patrick D. McMullen, Irmgard Merfort, Simon Messner, Christoph Meyer, Jessica Mwinyi, Dean J. Naisbitt, Andreas K. Nüssler, Peter Olinga, Francesco Pampaloni, Jingbo Pi, Linda Pluta, Stefan Przyborski, Anup Ramachandran, Vera Rogiers, Cliff Rowe, Celine Schelcher, Kathrin Schmich, Michael Schwarz, Bijay Singh, Ernst H. K. Stelzer, Bruno Stieger, Regina Stöber, Yuichi Sugiyama, Ciro Tetta, Wolfgang E. Thasler, Tamara Vanhaecke, Mathieu Vinken, Thomas S. Weiß, A Widera, Courtney G. Woods, Jinghai J. Xu, Kathy Yarborough, Jan G. Hengstler - Archives of Toxicology 2013 被引用: 1,275
- Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls
著者: Hartmut Jaeschke, Olamide B. Adelusi, Jephte Y. Akakpo, Nga Nguyen, Giselle Sánchez-Guerrero, David S. Umbaugh, Wen‐Xing Ding, Anup Ramachandran - Acta Pharmaceutica Sinica B 2021 被引用: 141
- Metabolism and Disposition of Acetaminophen: Recent Advances in Relation to Hepatotoxicity and Diagnosis
著者: Mitchell R. McGill, Hartmut Jaeschke - Pharmaceutical Research 2013 被引用: 693
- Acetaminophen Hepatotoxicity
著者: Anup Ramachandran, Hartmut Jaeschke - Seminars in Liver Disease 2019 被引用: 322
- Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity
著者: Hartmut Jaeschke, C. David Williams, Anup Ramachandran, Mary Lynn Bajt - Liver International 2011 被引用: 471
- Novel Therapeutic Approaches Against Acetaminophen-induced Liver Injury and Acute Liver Failure
著者: Hartmut Jaeschke, Jephte Y. Akakpo, David S. Umbaugh, Anup Ramachandran - Toxicological Sciences 2020 被引用: 196
- Bile Acids Induce Inflammatory Genes in Hepatocytes
著者: Katryn Allen, Hartmut Jaeschke, Bryan L. Copple - American Journal Of Pathology 2011 被引用: 498
- The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
著者: Mitchell R. McGill, Matthew R. Sharpe, C. David Williams, Muhammad Taha, Steven C. Curry, Hartmut Jaeschke - Journal of Clinical Investigation 2012 被引用: 763
- Peroxynitrite-Induced Mitochondrial and Endonuclease-Mediated Nuclear DNA Damage in Acetaminophen Hepatotoxicity
著者: Cathleen Cover, Abdellah Mansouri, Tamara R. Knight, Mary Lynn Bajt, John J. Lemasters, Dominique Pessayre, Hartmut Jaeschke - Journal of Pharmacology and Experimental Therapeutics 2005 被引用: 375
- Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice
著者: Hong‐Min Ni, Mitchell R. McGill, Xiaojuan Chao, Kuo Du, Jessica A. Williams, Yuchao Xie, Hartmut Jaeschke, Wen‐Xing Ding - Journal of Hepatology 2016 被引用: 232
- Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose
著者: Jephte Y. Akakpo, Anup Ramachandran, Steven C. Curry, Barry H. Rumack, Hartmut Jaeschke - Archives of Toxicology 2022 被引用: 108
- Activation of Autophagy Protects Against Acetaminophen–Induced Hepatotoxicity
著者: Hong‐Min Ni, Abigail B. Bockus, Nikki Boggess, Hartmut Jaeschke, Wen‐Xing Ding - Hepatology 2011 被引用: 428
- Animal models of drug-induced liver injury
著者: Mitchell R. McGill, Hartmut Jaeschke - Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2018 被引用: 197
- Emerging and established modes of cell death during acetaminophen-induced liver injury
著者: Hartmut Jaeschke, Anup Ramachandran, Xiaojuan Chao, Wen-Xing Ding - Archives of Toxicology 2019 被引用: 131
- Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts
著者: Hartmut Jaeschke - Journal of Gastroenterology and Hepatology 2011 被引用: 587
- Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy
著者: Hong-Min Ni, Benjamin L. Woolbright, Jessica A. Williams, Bryan L. Copple, Wei Cui, James P. Luyendyk, Hartmut Jaeschke, Wen-Xing Ding - Journal of Hepatology 2014 被引用: 269
- Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity
著者: Ahmed Ghallab, Reham Hassan, Ute Hofmann, Adrian Friebel, Zaynab Hobloss, Lisa Brackhagen, Brigitte Begher‐Tibbe, Maiju Myllys, Jörg Reinders, Nina Overbeck, Selahaddin Sezgin, Sebastian Zühlke, Abdel‐latif Seddek, Walaa Murad, Tim Brecklinghaus, Franziska Kappenberg, Jörg Rahnenführer, Daniela González, Christopher E. Goldring, Ian M. Copple, Rosemarie Marchan, Thomas Longerich, Mihael Vucur, Tom Luedde, Stephan Urban, Ali Canbay, Thomas Schreiter, Michael Trauner, Jephte Y. Akakpo, Mojtaba Olyaee, Steven C. Curry, Jan‐Peter Sowa, Hartmut Jaeschke, Stefan Hoehme, Jan G. Hengstler - Journal of Hepatology 2022 被引用: 81
- Acetaminophen-induced liver injury in rats and mice: Comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity
著者: Mitchell R. McGill, C. David Williams, Yuchao Xie, Anup Ramachandran, Hartmut Jaeschke - Toxicology and Applied Pharmacology 2012 被引用: 418
- A New Xenobiotic-Induced Mouse Model of Sclerosing Cholangitis and Biliary Fibrosis
著者: Peter Fickert, Ulrike Stöger, Andrea Fuchsbichler, Tarek Moustafa, Hanns–Ulrich Marschall, Andreas Weiglein, Oleksiy Tsybrovskyy, Hartmut Jaeschke, Kurt Zatloukal, Helmut Denk, Michael Trauner - American Journal Of Pathology 2007 被引用: 378
