Hartmut Wekerle
1973–2025 年に発表
- 123
- 論文数
- 28,787
- 被引用数
- 99
- h 指数
- 121
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine41%
- Neuroscience21.3%
- Biochemistry, Genetics and Molecular Biology20.4%
- Immunology and Microbiology15.5%
- Agricultural and Biological Sciences0.5%
- Nursing0.4%
- その他0.9%
トピック
- Multiple Sclerosis Research Studies7.6%
- Neuroinflammation and Neurodegeneration Mechanisms7.5%
- T-cell and B-cell Immunology5.4%
- Immunotherapy and Immune Responses4.4%
- Gut microbiota and health3.8%
- Immune Response and Inflammation3%
- その他68.3%
共著者
- Reinhard Hohlfeld42
- Hans Lassmann26
- Christopher Linington16
- Edgar Meinl16
- Harald Neumann13
- Klaus Dornmair13
- Gurumoorthy Krishnamoorthy10
- Naoto Kawakami9
- Alexander Flügel8
- Dieter E. Jenne8
- Markus Krumbholz7
- Kerstin Berer6
- Norbert Goebels6
- Tomas Olsson6
- Wolfgang E. F. Klinkert6
- Frank Weber5
- Joachim W. Ellwart5
- Lisa Ann Gerdes5
- Martin Kerschensteiner5
- Ralf Gold5
- Tania Kümpfel5
- Avraham Ben‐Nun4
- Francesca Aloisi4
- Francesca Odoardi4
全論文
- Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course
著者: Xiaoyuan Zhou, Ryan Baumann, Xiaohui Gao, Myra Mendoza, Sneha Singh, Ilana Katz Sand, Zongqi Xia, Laura M. Cox, Tanuja Chitnis, Hongsup Yoon, Laura Moles, Stacy J. Caillier, Adam Santaniello, Gail Ackermann, Adil Harroud, Robin Lincoln, Refujia Gomez, Antonio González Peña, Elise Digga, Daniel Hakim, Yoshiki Vázquez‐Baeza, Karthik Soman, Shannon Warto, Greg Humphrey, Mauricio Farez, Lisa Ann Gerdes, Jorge R. Oksenberg, Scott S. Zamvil, Siddharthan Chandran, Peter Connick, David Otaegui, Tamara Castillo‐Triviño, Stephen L. Hauser, Jeffrey M. Gelfand, Howard L. Weiner, Reinhard Hohlfeld, Hartmut Wekerle, Jennifer Graves, Amit Bar‐Or, Bruce Cree, Jorge Correale, Rob Knight, Sergio E. Baranzini - Cell 2022 被引用: 319
- Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice
著者: Kerstin Berer, Lisa Ann Gerdes, Egle Cekanaviciute, Xiaoming Jia, Liang Xiao, Zhongkui Xia, Chuan Liu, Luisa Klotz, Uta Stauffer, Sergio E. Baranzini, Tania Kümpfel, Reinhard Hohlfeld, Gurumoorthy Krishnamoorthy, Hartmut Wekerle - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 被引用: 936
- Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
著者: Kerstin Berer, Marsilius Mues, Michail Koutrolos, Zakeya Al Rasbi, Marina Boziki, Caroline Johner, Hartmut Wekerle, Gurumoorthy Krishnamoorthy - Nature 2011 被引用: 1,252
- γ-secretase directly sheds the survival receptor BCMA from plasma cells
著者: Sarah Laurent, Franziska Hoffmann, Peer‐Hendrik Kuhn, Qingyu Cheng, Yuanyuan Chu, Marc Schmidt‐Supprian, Stefanie M. Hauck, Elisabeth Schuh, Markus Krumbholz, Heike Rübsamen, Johanna Wanngren, Mohsen Khademi, Tomas Olsson, Tobias Alexander, Falk Hiepe, Hans‐Walter Pfister, Frank Weber, Dieter E. Jenne, Hartmut Wekerle, Reinhard Hohlfeld, Stefan F. Lichtenthaler, Edgar Meinl - Nature Communications 2015 被引用: 364
- Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
著者: Ingo Bartholomäus, Naoto Kawakami, Francesca Odoardi, Christian Schläger, Djordje Miljković, Joachim W. Ellwart, Wolfgang E. F. Klinkert, Cassandra Flügel‐Koch, Thomas B. Issekutz, Hartmut Wekerle, Alexander Flügel - Nature 2009 被引用: 682
- Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis
著者: Tilman Schneider‐Hohendorf, Lisa Ann Gerdes, Béatrice Pignolet, Rachel M. Gittelman, Patrick Ostkamp, Florian Rubelt, Catarina Raposo, Björn Tackenberg, Marianne Riepenhausen, Claudia Janoschka, Christian Wünsch, Florence Bucciarelli, Andrea Flierl‐Hecht, Eduardo Beltrán, Tania Kümpfel, Katja Anslinger, Catharina C. Groß, Heidi Chapman, Ian M. Kaplan, David Brassat, Hartmut Wekerle, Martin Kerschensteiner, Luisa Klotz, Jan D. Lünemann, Reinhard Hohlfeld, Roland Liblau, Heinz Wiendl, Nicholas Schwab - The Journal of Experimental Medicine 2022 被引用: 85
- MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies
著者: Nicolas Molnarfi, Ulf Schulze‐Topphoff, Martin S. Weber, Juan C. Patarroyo, Thomas Prod’homme, Michel Varrin‐Doyer, Aparna Shetty, Christopher Linington, Anthony Slavin, Juan Hidalgo, Dieter E. Jenne, Hartmut Wekerle, Raymond A. Sobel, Claude C.A. Bernard, Mark J. Shlomchik, Scott S. Zamvil - The Journal of Experimental Medicine 2013 被引用: 415
- MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47
著者: Andreas Junker, Markus Krumbholz, Sylvia Eisele, Hema Mohan, Florian Augstein, Robert A. Bittner, Hans Lassmann, Hartmut Wekerle, Reinhard Hohlfeld, Edgar Meinl - Brain 2009 被引用: 592
- T cells become licensed in the lung to enter the central nervous system
著者: Francesca Odoardi, Christopher Sie, Kristina Streyl, Vijay K. Ulaganathan, Christian Schläger, Dmitri Lodygin, Klaus Heckelsmiller, Wilfried Nietfeld, Joachim W. Ellwart, Wolfgang E. F. Klinkert, Claudio Lottaz, Mikhail Nosov, Volker Brinkmann, Rainer Spang, Hans Lehrach, Martin Vingron, Hartmut Wekerle, Cassandra Flügel‐Koch, Alexander Flügel - Nature 2012 被引用: 438
- Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins
著者: Simone M. Brändle, Birgit Obermeier, Makbule Şenel, Jessica Bruder, Reinhard Mentele, Mohsen Khademi, Tomas Olsson, Hayrettin Tumani, Wolfgang Kristoferitsch, Friedrich Lottspeich, Hartmut Wekerle, Reinhard Hohlfeld, Klaus Dornmair - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 190
- Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS
著者: Michail Koutrolos, Kerstin Berer, Naoto Kawakami, Hartmut Wekerle, Gurumoorthy Krishnamoorthy - Acta Neuropathologica Communications 2014 被引用: 129
- Activated Human T Cells, B Cells, and Monocytes Produce Brain-derived Neurotrophic Factor In Vitro and in Inflammatory Brain Lesions: A Neuroprotective Role of Inflammation?
著者: Martin Kerschensteiner, Eike Gallmeier, Lüder Behrens, Vivian Vargas Leal, Thomas Misgeld, Wolfgang E. F. Klinkert, Roland Kolbeck, Edmund Hoppe, R L Oropeza-Wekerle, Ilse Bartke, Christine Stadelmann, Hans Lassmann, Hartmut Wekerle, Reinhard Hohlfeld - The Journal of Experimental Medicine 1999 被引用: 1,024
- The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+ T lymphocytes as pathogenic effectors and therapeutic targets
著者: Reinhard Hohlfeld, Klaus Dornmair, Edgar Meinl, Hartmut Wekerle - The Lancet Neurology 2015 被引用: 198
- Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells
著者: Bernadette Pöllinger, Gurumoorthy Krishnamoorthy, Kerstin Berer, Hans Lassmann, Michael R. Bösl, Robert R. Dunn, Helena S. Domingues, Andreas Holz, Florian C. Kurschus, Hartmut Wekerle - The Journal of Experimental Medicine 2009 被引用: 291
- Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis
著者: Birgit Obermeier, Reinhard Mentele, Joachim Malotka, Josef Kellermann, Tania Kümpfel, Hartmut Wekerle, Friedrich Lottspeich, Reinhard Hohlfeld, Klaus Dornmair - Nature Medicine 2008 被引用: 290
- Neurotrophins inhibit major histocompatibility class II inducibility of microglia: Involvement of the p75 neurotrophin receptor
著者: Harald Neumann, Thomas Misgeld, Kenji Matsumuro, Hartmut Wekerle - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 被引用: 283
- Extracellular Matrix in Multiple Sclerosis Lesions: Fibrillar Collagens, Biglycan and Decorin are Upregulated and Associated with Infiltrating Immune Cells
著者: Hema Mohan, Markus Krumbholz, Rakhi Sharma, Sylvia Eisele, Andreas Junker, Michael Sixt, Jia Newcombe, Hartmut Wekerle, Reinhard Hohlfeld, Hans Lassmann, Edgar Meinl - Brain Pathology 2010 被引用: 160
- BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
著者: Markus Krumbholz, Diethilde Theil, Tobias Derfuß, Andreas Rosenwald, Frank Schrader, Camelia‐Maria Monoranu, Susan L. Kalled, Donna M. Hess, Barbara Serafini, Francesca Aloisi, Hartmut Wekerle, Reinhard Hohlfeld, Edgar Meinl - The Journal of Experimental Medicine 2005 被引用: 483
- B Lymphocytes Producing Demyelinating Autoantibodies: Development and Function in Gene-targeted Transgenic Mice
著者: Tobias Litzenburger, Reinhard Fässler, Jan Bauer, Hans Lassmann, Christopher Linington, Hartmut Wekerle, Antonio Iglesias - The Journal of Experimental Medicine 1998 被引用: 257
- From classic to spontaneous and humanized models of multiple sclerosis: Impact on understanding pathogenesis and drug development
著者: Avraham Ben‐Nun, Nathali Kaushansky, Naoto Kawakami, Gurumoorthy Krishnamoorthy, Kerstin Berer, Roland Liblau, Reinhard Hohlfeld, Hartmut Wekerle - Journal of Autoimmunity 2014 被引用: 159
- The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis
著者: Avraham Ben‐Nun, Hartmut Wekerle, Irun R. Cohen - European Journal of Immunology 1981 被引用: 918
- Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis
著者: Helena S. Domingues, Marsilius Mues, Hans Lassmann, Hartmut Wekerle, Gurumoorthy Krishnamoorthy - PLoS ONE 2010 被引用: 222
- Brain Autoimmunity and Intestinal Microbiota: 100 Trillion Game Changers
著者: Hartmut Wekerle - Trends in Immunology 2017 被引用: 102
- Multiple sclerosis: Brain-infiltrating CD8 + T cells persist as clonal expansions in the cerebrospinal fluid and blood
著者: Christian Skulina, Stephan Schmidt, Klaus Dornmair, Holger Babbe, Axel Roers, Klaus Rajewsky, Hartmut Wekerle, Reinhard Hohlfeld, Norbert Goebels - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 被引用: 346
