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Heather P. Harding

1991–2024 年に発表

94
論文数
53,573
被引用数
84
h 指数
93
i10 指数

被引用数

Heather P. Harding の年別被引用数1983 年: 被引用 1 件1990 年: 被引用 2 件1992 年: 被引用 13 件1993 年: 被引用 14 件1994 年: 被引用 11 件1995 年: 被引用 25 件1996 年: 被引用 44 件1997 年: 被引用 64 件1998 年: 被引用 54 件1999 年: 被引用 81 件2000 年: 被引用 165 件2001 年: 被引用 184 件2002 年: 被引用 327 件2003 年: 被引用 377 件2004 年: 被引用 538 件2005 年: 被引用 570 件2006 年: 被引用 702 件2007 年: 被引用 799 件2008 年: 被引用 686 件2009 年: 被引用 724 件2010 年: 被引用 738 件2011 年: 被引用 714 件2012 年: 被引用 906 件2013 年: 被引用 906 件2014 年: 被引用 957 件2015 年: 被引用 818 件2016 年: 被引用 745 件2017 年: 被引用 745 件2018 年: 被引用 683 件2019 年: 被引用 1,845 件2020 年: 被引用 2,035 件2021 年: 被引用 1,894 件2022 年: 被引用 1,433 件2023 年: 被引用 915 件2024 年: 被引用 1,508 件2025 年: 被引用 621 件2026 年: 被引用 13 件1984〜1989 年は被引用が無いため表示していません1991 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 5,526 件、この内訳の 31.3%中国: 引用元論文 1,993 件、この内訳の 11.3%イギリス: 引用元論文 1,060 件、この内訳の 6%ドイツ: 引用元論文 902 件、この内訳の 5.1%日本: 引用元論文 797 件、この内訳の 4.5%カナダ: 引用元論文 697 件、この内訳の 3.9%フランス: 引用元論文 682 件、この内訳の 3.9%イタリア: 引用元論文 557 件、この内訳の 3.1%オーストラリア: 引用元論文 407 件、この内訳の 2.3%韓国: 引用元論文 390 件、この内訳の 2.2%スイス: 引用元論文 335 件、この内訳の 1.9%スペイン: 引用元論文 326 件、この内訳の 1.8%
0%31.3%その他 22.7%

機関

分野

  • Biochemistry, Genetics and Molecular Biology59.6%
  • Medicine26.6%
  • Neuroscience5.7%
  • Immunology and Microbiology4.4%
  • Agricultural and Biological Sciences1%
  • Nursing0.7%
  • その他2%

トピック

  • Endoplasmic Reticulum Stress and Disease13.8%
  • Autophagy in Disease and Therapy6%
  • RNA regulation and disease3.1%
  • Pancreatic function and diabetes2.8%
  • RNA Research and Splicing2%
  • Mitochondrial Function and Pathology1.9%
  • その他70.4%

共著者

全論文

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  1. An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

    著者: Heather P. Harding, Yuhong Zhang, Huiquing Zeng, Isabel Novoa, Phoebe D. Lu, Marcella A. Calfon, Navid Sadri, Chi Young Yun, Brian Popko, Richard S. Paules, David F. Stojdl, John C. Bell, Thore Hettmann, Jeffrey M. Leiden, David Ron - Molecular Cell 2003 被引用: 3,314

  2. Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

    著者: Heather P. Harding, Isabel Novoa, Yuhong Zhang, Huiqing Zeng, Ronald C. Wek, Matthieu Schapira, David Ron - Molecular Cell 2000 被引用: 3,241

  3. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

    著者: Heather P. Harding, Yuhong Zhang, David Ron - Nature 1999 被引用: 3,347

  4. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

    著者: Anne Bertolotti, Yuhong Zhang, Linda M. Hendershot, Heather P. Harding, David Ron - Nature Cell Biology 2000 被引用: 2,860

  5. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

    著者: Marcella A. Calfon, Huiqing Zeng, Fumihiko Urano, Jeffery H. Till, Stevan R. Hubbard, Heather P. Harding, Scott G. Clark, David Ron - Nature 2002 被引用: 2,889

  6. Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1

    著者: Fumihiko Urano, Xiao-Zhong Wang, Anne Bertolotti, Yuhong Zhang, Peter Chung, Heather P. Harding, David Ron - Science 2000 被引用: 2,992

  7. GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans

    著者: Satish Patel, Anna Álvarez-Guaita, Audrey Melvin, Debra Rimmington, Alessia Dattilo, Emily L. Miedzybrodzka, Irène Cimino, Anne‐Catherine Maurin, Geoffrey Roberts, Claire L. Meek, Sam Virtue, Lauren M. Sparks, Stephanie A. Parsons, Leanne M. Redman, George A. Bray, Alice P. Liou, Rachel Woods, Siôn Parry, Per Bendix Jeppesen, Anders J. Kolnes, Heather P. Harding, David Ron, Antonio Vidal‐Puig, Frank Reimann, Fiona M. Gribble, Carl J. Hulston, I. Sadaf Farooqi, Pierre Fafournoux, Steven R. Smith, Jorgen Jensen, Danna M. Breen, Zhidan Wu, Bei B. Zhang, Anthony P. Coll, David B. Savage, Stephen O’Rahilly - Cell Metabolism 2019 被引用: 499

  8. GDF15 mediates the effects of metformin on body weight and energy balance

    著者: Anthony P. Coll, Michael Chen, Pranali Taskar, Debra Rimmington, Satish Patel, John A. Tadross, Irène Cimino, Ming Yang, Paul Welsh, Sam Virtue, Deborah A. Goldspink, Emily L. Miedzybrodzka, Adam R. Konopka, Raul Ruiz Esponda, Jeffrey Huang, Y. C. Loraine Tung, Sergio Rodríguez‐Cuenca, Rute A. Tomaz, Heather P. Harding, Audrey Melvin, Giles S.H. Yeo, David Preiss, Antonio Vidal‐Puig, Ludovic Vallier, K. Sreekumaran Nair, Nicholas J. Wareham, David Ron, Fiona M. Gribble, Frank Reimann, Naveed Sattar, David B. Savage, Bernard B. Allan, Stephen O’Rahilly - Nature 2019 被引用: 570

  9. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

    著者: Stefan J. Marciniak, Chi Young Yun, Seiichi Oyadomari, Isabel Novoa, Yuhong Zhang, Rivka Jungreis, Kazuhiro Nagata, Heather P. Harding, David Ron - Genes & Development 2004 被引用: 1,989

  10. GCN2 Kinase in T Cells Mediates Proliferative Arrest and Anergy Induction in Response to Indoleamine 2,3-Dioxygenase

    著者: David H. Munn, Madhav Sharma, Babak Baban, Heather P. Harding, Yuhong Zhang, David Ron, Andrew L. Mellor - Immunity 2005 被引用: 1,245

  11. Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response

    著者: Heather P. Harding, Yuhong Zhang, Anne Bertolotti, Huiqing Zeng, David Ron - Molecular Cell 2000 被引用: 2,008

  12. Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

    著者: Isabel Novoa, Huiqing Zeng, Heather P. Harding, David Ron - The Journal of Cell Biology 2001 被引用: 1,373

  13. Predicting the mutations generated by repair of Cas9-induced double-strand breaks

    著者: Felicity Allen, Luca Crepaldi, Clara Alsinet, Alexander Strong, Vitalii Kleshchevnikov, Pietro De Angeli, Petra Páleníková, Anton Khodak, Vladimir Yu Kiselev, Michael Kosicki, Andrew Bassett, Heather P. Harding, Yaron Galanty, Francisco Muñoz‐Martínez, Emmanouil Metzakopian, Stephen P. Jackson, Leopold Parts - Nature Biotechnology 2018 被引用: 527

  14. Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

    著者: Phoebe D. Lu, Heather P. Harding, David Ron - The Journal of Cell Biology 2004 被引用: 993

  15. A Selective Inhibitor of eIF2α Dephosphorylation Protects Cells from ER Stress

    著者: Michael Boyce, Kevin F. Bryant, Céline Jousse, Kai Long, Heather P. Harding, Donalyn Scheuner, Randal J. Kaufman, Dawei Ma, Donald M. Coen, David Ron, Junying Yuan - Science 2005 被引用: 1,412

  16. Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

    著者: Gang Li, Marco Mongillo, King‐Tung Chin, Heather P. Harding, David Ron, Andrew R. Marks, Ira Tabas - The Journal of Cell Biology 2009 被引用: 583

  17. Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

    著者: Jyoti Nangalia, Charles Massie, E. Joanna Baxter, Francesca Nice, Gunes Gundem, David C. Wedge, Edward Avezov, J. Li, Karoline Kollmann, David G. Kent, Aziz Aziz, Anna L. Godfrey, Jonathan Hinton, Iñigo Martincorena, Peter Van Loo, Amy V. Jones, Paola Guglielmelli, Patrick Tarpey, Heather P. Harding, John D. Fitzpatrick, Calum T Goudie, Christina A. Ortmann, Stephen J. Loughran, Keiran Raine, Daniel Jones, Adam P. Butler, Jon W. Teague, Sarah O’Meara, Stuart McLaren, Michele Leonardo Bianchi, Yvonne Silber, D. Dimitropoulou, David Bloxham, Laura Mudie, Mark Maddison, Ben Robinson, Clodagh Keohane, Cathy MacLean, Kate Hill, Kim Orchard, Sheral Raina Tauro, Ming‐Qing Du, Mel Greaves, David Bowen, Brian J.P. Huntly, Claire Harrison, Nicholas C.P. Cross, David Ron, Alessandro M. Vannucchi, Elli Papaemmanuil, Peter J. Campbell, Anthony R. Green - New England Journal of Medicine 2013 被引用: 1,737

  18. The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells

    著者: Heather P. Harding, A. Ordóñez, Felicity Allen, Leopold Parts, Alison J. Inglis, Roger Williams, David Ron - eLife 2019 被引用: 178

  19. Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

    著者: Takunari Yoneda, Cristina Benedetti, Fumihiko Urano, Scott G. Clark, Heather P. Harding, David Ron - Journal of Cell Science 2004 被引用: 670

  20. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

    著者: Benedict C. S. Cross, Peter J. Bond, Paweł Sadowski, Babal K. Jha, Jaroslav Žák, Jonathan M. Goodman, Robert H. Silverman, Thomas A. Neubert, Ian R. Baxendale, David Ron, Heather P. Harding - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 被引用: 594

  21. Diabetes Mellitus and Exocrine Pancreatic Dysfunction in Perk−/− Mice Reveals a Role for Translational Control in Secretory Cell Survival

    著者: Heather P. Harding, Huiqing Zeng, Yuhong Zhang, Rivka Jungries, Peter Chung, Heidi Plesken, David D. Sabatini, David Ron - Molecular Cell 2001 被引用: 1,213

  22. Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

    著者: M.S. Halliday, Helois Radford, Yusuke Sekine, Julie A. Moreno, Nicholas Verity, John Le Quesne, Catharine A. Ortori, David A. Barrett, Christophe Fromont, Peter M. Fischer, Heather P. Harding, David Ron, Giovanna R. Mallucci - Cell Death and Disease 2015 被引用: 384

  23. A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response

    著者: Niko Amin-Wetzel, Reuben A. Saunders, Maarten J. Kamphuis, Cláudia Rato, Steffen Preißler, Heather P. Harding, David Ron - Cell 2017 被引用: 261

  24. Targeting the unfolded protein response in disease

    著者: Claudio Hetz, Éric Chevet, Heather P. Harding - Nature Reviews Drug Discovery 2013 被引用: 902