Helen E. Heslop
1990–2025 年に発表
- 170
- 論文数
- 36,447
- 被引用数
- 102
- h 指数
- 168
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine79.7%
- Immunology and Microbiology9.4%
- Biochemistry, Genetics and Molecular Biology9.1%
- Engineering0.6%
- Neuroscience0.6%
- Materials Science0.2%
- その他0.4%
トピック
- CAR-T cell therapy research19.6%
- Immune Cell Function and Interaction8.2%
- Virus-based gene therapy research7%
- Immunotherapy and Immune Responses5.5%
- Nanowire Synthesis and Applications4%
- Viral-associated cancers and disorders3.3%
- その他52.4%
共著者
- Malcolm K. Brenner109
- Cliona M. Rooney102
- Adrian P. Gee51
- Gianpietro Dotti43
- Catherine M. Bollard41
- Bambi Grilley39
- Barbara Savoldo37
- Ann M. Leen35
- Robert A. Krance33
- Stephen Gottschalk32
- Meng-Fen Wu31
- Hao Liu30
- Carlos A. Ramos27
- George Carrum22
- Tao Wang19
- Premal Lulla18
- Huimin Zhang16
- Juan F. Vera16
- M. Helen Huls16
- Olga Dakhova16
- Caridad Martinez15
- Zhuyong Mei15
- Birju Mehta12
- Catherine Robertson12
全論文
- HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma
著者: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Kevin Bielamowicz, Mamta Kalra, Daniel Landi, Catherine Robertson, Tara Gray, Oumar Diouf, Amanda Wakefield, Alexia Ghazi, Claudia Gerken, Zhongzhen Yi, Aidin Ashoori, Meng-Fen Wu, Hao Liu, Cliona M. Rooney, Gianpietro Dotti, Adrian P. Gee, Jack Su, Yvonne Kew, David S. Baskin, Yi Jonathan Zhang, Pamela New, Bambi Grilley, Milica Stojakovic, John Hicks, Suzanne Z. Powell, Malcolm K. Brenner, Helen E. Heslop, Robert G. Grossman, Winfried S. Wels, Stephen Gottschalk - JAMA Oncology 2017 被引用: 837
- Unanswered questions following reports of secondary malignancies after CAR-T cell therapy
著者: Bruce L. Levine, Marcelo C. Pasquini, John E. Connolly, David L. Porter, Michael P. Gustafson, Jaap Jan Boelens, Edwin M. Horwitz, Stephan A. Grupp, Marcela V. Maus, Frederick L. Locke, Fabio Ciceri, Annalisa Ruggeri, John A. Snowden, Helen E. Heslop, Crystal L. Mackall, Carl H. June, Anna M. Sureda, Miguel‐Angel Perales - Nature Medicine 2024 被引用: 196
- Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15
著者: Yang Xu, Ming Zhang, Carlos A. Ramos, April Durett, Enli Liu, Olga Dakhova, Hao Liu, Chad J. Creighton, Adrian P. Gee, Helen E. Heslop, Cliona M. Rooney, Barbara Savoldo, Gianpietro Dotti - Blood 2014 被引用: 736
- Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
著者: Antonio Di Stasi, Siok‐Keen Tey, Gianpietro Dotti, Yuriko Fujita, Alana A. Kennedy‐Nasser, Caridad Martinez, Karin Straathof, Enli Liu, April Durett, Bambi Grilley, Hao Liu, Carolina Colli Cruz, Barbara Savoldo, Adrian P. Gee, John Schindler, Robert A. Krance, Helen E. Heslop, David M. Spencer, Cliona M. Rooney, Malcolm K. Brenner - New England Journal of Medicine 2011 被引用: 1,495
- Human Epidermal Growth Factor Receptor 2 (HER2) –Specific Chimeric Antigen Receptor–Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma
著者: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian P. Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Winfried S. Wels, Lisa L. Wang, Peter M. Anderson, Stephen Gottschalk - Journal of Clinical Oncology 2015 被引用: 979
- Scalable Manufacturing of CAR T Cells for Cancer Immunotherapy
著者: Mohamed Abou‐El‐Enein, Magdi Elsallab, Steven A. Feldman, Andrew D. Fesnak, Helen E. Heslop, Peter Marks, Brian G. Till, Gerhard Bauer, Barbara Savoldo - Blood Cancer Discovery 2021 被引用: 295
- CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma
著者: Andras Heczey, Chrystal U. Louis, Barbara Savoldo, Olga Dakhova, April Durett, Bambi Grilley, Hao Liu, Mengfeng F. Wu, Zhuyong Mei, Adrian P. Gee, Birju Mehta, Huimin Zhang, Nadia Mahmood, Haruko Tashiro, Helen E. Heslop, Gianpietro Dotti, Cliona M. Rooney, Malcolm K. Brenner - Molecular Therapy 2017 被引用: 530
- Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma
著者: Chrystal U. Louis, Barbara Savoldo, Gianpietro Dotti, Martin Pulé, Eric Yvon, Gary D. Myers, Claudia Rössig, Heidi V. Russell, Oumar Diouf, Enli Liu, Hao Liu, Meng-Fen Wu, Adrian P. Gee, Zhuyong Mei, Cliona M. Rooney, Helen E. Heslop, Malcolm K. Brenner - Blood 2011 被引用: 1,171
- Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers
著者: Pavel Sumazin, Andras Heczey, John M. Maris, Antonino Montalbano, Amy N. Courtney, Jennifer Pogoriler, Sachin G. Thakkar, Gianpietro Dotti, David Steffin, Premal Lulla, Natalia Lapteva, Dolores López‐Terrada, Zhuyong Mei, Carlos A. Ramos, Malcolm K. Brenner, Ramy Sweidan, Stephen Gottschalk, Huimin Zhang, Nisha Ghatwai, Navin Varadarajan, Leonid S. Metelitsa, Kalyani Patel, Helen E. Heslop, Azlann Arnett, Prakash Masand, Tao Wang, Tannaz Armaghany, Julien Fleurence, Purva Rathi, Bambi Grilley, Daniel Martínez, Deborah Lyon - Nature 2024 被引用: 207
- An inducible caspase 9 safety switch for T-cell therapy
著者: Karin Straathof, Martin Pulé, Patricia Yotnda, Gianpietro Dotti, Elio F. Vanin, Malcolm K. Brenner, Helen E. Heslop, David M. Spencer, Cliona M. Rooney - Blood 2005 被引用: 741
- Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
著者: Martin Pulé, Barbara Savoldo, Gary D. Myers, Claudia Rössig, Heidi V. Russell, Gianpietro Dotti, M. Helen Huls, Enli Liu, Adrian P. Gee, Zhuyong Mei, Éric Yvon, Heidi L. Weiss, Hao Liu, Cliona M. Rooney, Helen E. Heslop, Malcolm K. Brenner - Nature Medicine 2008 被引用: 1,190
- Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma
著者: Carlos A. Ramos, Natalie S. Grover, Anne Beaven, Premal Lulla, Meng-Fen Wu, Anastasia Ivanova, Tao Wang, Thomas C. Shea, Cliona M. Rooney, Christopher Dittus, Steven I. Park, Adrian P. Gee, Paul W. Eldridge, Kathryn McKay, Birju Mehta, Catherine Cheng, Faith Brianne Buchanan, Bambi Grilley, Kaitlin Morrison, Malcolm K. Brenner, Jonathan S. Serody, Gianpietro Dotti, Helen E. Heslop, Barbara Savoldo - Journal of Clinical Oncology 2020 被引用: 380
- In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin’s Lymphomas
著者: Carlos A. Ramos, Rayne H. Rouce, Catherine Robertson, A. Reyna, Neeharika Narala, Gayatri Vyas, Birju Mehta, Huimin Zhang, Olga Dakhova, George Carrum, Rammurti T. Kamble, Adrian P. Gee, Zhuyong Mei, Meng-Fen Wu, Hao Liu, Bambi Grilley, Cliona M. Rooney, Helen E. Heslop, Malcolm K. Brenner, Barbara Savoldo, Gianpietro Dotti - Molecular Therapy 2018 被引用: 293
- Engineered off-the-shelf therapeutic T cells resist host immune rejection
著者: Feiyan Mo, Norihiro Watanabe, Mary K. McKenna, John Hicks, Madhuwanti Srinivasan, Diogo Gomes‐Silva, Erden Atilla, Tyler S. Smith, Pınar Ataca Atilla, Royce Ma, David H. Quach, Helen E. Heslop, Malcolm K. Brenner, Maksim Mamonkin - Nature Biotechnology 2020 被引用: 143
- Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation
著者: Ifigeneia Tzannou, Αναστασία Παπαδοπούλου, Swati Naik, Kathryn Leung, Caridad Martinez, Carlos A. Ramos, George Carrum, Ghadir Sasa, Premal Lulla, Ayumi Watanabe, Manik Kuvalekar, Adrian P. Gee, Meng-Fen Wu, Hao Liu, Bambi Grilley, Robert A. Krance, Stephen Gottschalk, Malcolm K. Brenner, Cliona M. Rooney, Helen E. Heslop, Ann M. Leen, Bilal Omer - Journal of Clinical Oncology 2017 被引用: 450
- CD28 costimulation improves expansion and persistence of chimeric antigen receptor–modified T cells in lymphoma patients
著者: Barbara Savoldo, Carlos Almeida Ramos, Enli Liu, Martha P. Mims, Michael J. Keating, George Carrum, Rammurti T. Kamble, Catherine M. Bollard, Adrian P. Gee, Zhuyong Mei, Hao Liu, Bambi Grilley, Cliona M. Rooney, Helen E. Heslop, Malcolm K. Brenner, Gianpietro Dotti - Journal of Clinical Investigation 2011 被引用: 1,013
- Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer
著者: Somala Mohammed, Sujita Sukumaran, Pradip Bajgain, Norihiro Watanabe, Helen E. Heslop, Cliona M. Rooney, Malcolm K. Brenner, William E. Fisher, Ann M. Leen, Juan F. Vera - Molecular Therapy 2017 被引用: 280
- Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma
著者: Meenakshi Hegde, Sujith K. Joseph, Farzana Pashankar, Christopher DeRenzo, Khaled Sanber, Shoba A. Navai, Tiara T. Byrd, John Hicks, Mina L. Xu, Claudia Gerken, Mamta Kalra, Catherine Robertson, Huimin Zhang, Ankita Shree, Birju Mehta, Olga Dakhova, Vita S. Salsman, Bambi Grilley, Adrian P. Gee, Gianpietro Dotti, Helen E. Heslop, Malcolm K. Brenner, Winfried S. Wels, Stephen Gottschalk, Nabil Ahmed - Nature Communications 2020 被引用: 167
- Combinational Targeting Offsets Antigen Escape and Enhances Effector Functions of Adoptively Transferred T Cells in Glioblastoma
著者: Meenakshi Hegde, Amanda Corder, Kevin Chow, Malini Mukherjee, Aidin Ashoori, Yvonne Kew, Yi Jonathan Zhang, David S. Baskin, Fatima A. Merchant, Vita S. Brawley, Tiara T. Byrd, Simone Krebs, Meng Wu, Hao Liu, Helen E. Heslop, Stephen Gottachalk, Eric Yvon, Nabil Ahmed - Molecular Therapy 2013 被引用: 372
- Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study
著者: Carolina Colli Cruz, Kenneth Micklethwaite, Barbara Savoldo, Carlos A. Ramos, Sharon Lam, Stephanie Ku, Oumar Diouf, Enli Liu, A. John Barrett, Sawa Ito, Elizabeth J. Shpall, Robert A. Krance, Rammurti T. Kamble, George Carrum, Chitra Hosing, Adrian P. Gee, Zhuyong Mei, Bambi Grilley, Helen E. Heslop, Cliona M. Rooney, Malcolm K. Brenner, Catherine M. Bollard, Gianpietro Dotti - Blood 2013 被引用: 506
- Randomized Phase III BMT CTN Trial of Calcineurin Inhibitor–Free Chronic Graft-Versus-Host Disease Interventions in Myeloablative Hematopoietic Cell Transplantation for Hematologic Malignancies
著者: Leo Luznik, Marcelo C. Pasquini, Brent Logan, Robert J. Soiffer, Juan Wu, Steven M. Devine, Nancy Geller, Sergio Giralt, Helen E. Heslop, Mary M. Horowitz, Richard J. Jones, Mark R. Litzow, Adam Mendizabal, Lori Muffly, Eneida R. Nemecek, Lynn O'Donnell, Richard J. O'Reilly, Raquel Palencia, Johannes Schetelig, Leyla Shune, Scott R. Solomon, Sumithira Vasu, Vincent T. Ho, Miguel-Angel Perales - Journal of Clinical Oncology 2021 被引用: 168
- Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial
著者: Meenakshi Hegde, Shoba A. Navai, Christopher DeRenzo, Sujith K. Joseph, Khaled Sanber, Meng‐Fen Wu, Ahmed Z. Gad, Katherine A. Janeway, Matthew Campbell, Dolores Mullikin, Zeid Nawas, Catherine Robertson, Pretty Mathew, Huimin Zhang, Birju Mehta, Raksha R. Bhat, Angela M. Major, Ankita Shree, Claudia Gerken, Mamta Kalra, Rikhia Chakraborty, Sachin G. Thakkar, Olga Dakhova, Vita S. Salsman, Bambi Grilley, Natalia Lapteva, Adrian P. Gee, Gianpietro Dotti, Riyue Bao, Ahmed Hamed Salem, Tao Wang, Malcolm K. Brenner, Helen E. Heslop, Winfried S. Wels, John Hicks, Stephen Gottschalk, Nabil Ahmed - Nature Cancer 2024 被引用: 80
- Phase I Trial of GD2.CART Cells Augmented With Constitutive Interleukin-7 Receptor for Treatment of High-Grade Pediatric CNS Tumors
著者: Frank Y. Lin, Austin J. Stuckert, Candise Tat, Mark D. White, Lucia Ruggieri, Huimin Zhang, Birju Mehta, Natalia Lapteva, Zhuyong Mei, Angela M. Major, Sachin G. Thakkar, Thomas Shum, Kathan Parikh, Meng-Fen Wu, Holly Lindsay, Lauren Scherer, Meghan Shekar, Darryl Kinnear, Melissa M. Blessing, Patricia Baxter, Tao Wang, Bambi Grilley, Karen Moeller, John Hicks, Angshumoy Roy, Jamie Anastas, Fatema Malbari, Guillermo Aldave, Murali Chintagumpala, Susan Blaney, D. Williams Parsons, Malcolm K. Brenner, Helen E. Heslop, Cliona M. Rooney, Bilal Omer - Journal of Clinical Oncology 2024 被引用: 74
- HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors
著者: Nabil Ahmed, Vita S. Salsman, Yvonne Kew, Donald R. Shaffer, Suzanne Z. Powell, Yi J Zhang, Robert G. Grossman, Helen E. Heslop, Stephen Gottschalk - Clinical Cancer Research 2010 被引用: 386
