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Hideyoshi Harashima

1984–2025 年に発表

189
論文数
21,578
被引用数
87
h 指数
181
i10 指数

被引用数

Hideyoshi Harashima の年別被引用数1975 年: 被引用 1 件1986 年: 被引用 1 件1990 年: 被引用 1 件1991 年: 被引用 1 件1994 年: 被引用 1 件1995 年: 被引用 3 件1996 年: 被引用 2 件1997 年: 被引用 2 件1998 年: 被引用 7 件1999 年: 被引用 1 件2000 年: 被引用 5 件2001 年: 被引用 10 件2002 年: 被引用 7 件2003 年: 被引用 21 件2004 年: 被引用 34 件2005 年: 被引用 35 件2006 年: 被引用 93 件2007 年: 被引用 149 件2008 年: 被引用 144 件2009 年: 被引用 183 件2010 年: 被引用 230 件2011 年: 被引用 233 件2012 年: 被引用 256 件2013 年: 被引用 243 件2014 年: 被引用 232 件2015 年: 被引用 220 件2016 年: 被引用 214 件2017 年: 被引用 231 件2018 年: 被引用 178 件2019 年: 被引用 633 件2020 年: 被引用 892 件2021 年: 被引用 825 件2022 年: 被引用 903 件2023 年: 被引用 849 件2024 年: 被引用 1,188 件2025 年: 被引用 841 件2026 年: 被引用 18 件1976〜1985 年は被引用が無いため表示していません1987〜1989 年は被引用が無いため表示していません1992〜1993 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図中国: 引用元論文 1,762 件、この内訳の 22.2%アメリカ合衆国: 引用元論文 1,539 件、この内訳の 19.4%日本: 引用元論文 525 件、この内訳の 6.6%インド: 引用元論文 354 件、この内訳の 4.5%イギリス: 引用元論文 295 件、この内訳の 3.7%ドイツ: 引用元論文 287 件、この内訳の 3.6%韓国: 引用元論文 242 件、この内訳の 3%イタリア: 引用元論文 192 件、この内訳の 2.4%イラン: 引用元論文 184 件、この内訳の 2.3%フランス: 引用元論文 183 件、この内訳の 2.3%カナダ: 引用元論文 180 件、この内訳の 2.3%オーストラリア: 引用元論文 178 件、この内訳の 2.2%
0%22.2%その他 25.5%

機関

分野

  • Biochemistry, Genetics and Molecular Biology50.9%
  • Medicine14.3%
  • Materials Science14.1%
  • Immunology and Microbiology9.2%
  • Engineering5.4%
  • Pharmacology, Toxicology and Pharmaceutics3.1%
  • その他3%

トピック

  • RNA Interference and Gene Delivery16.3%
  • Advanced biosensing and bioanalysis techniques9.1%
  • Nanoparticle-Based Drug Delivery7.5%
  • Nanoplatforms for cancer theranostics4.2%
  • Immunotherapy and Immune Responses3.3%
  • Virus-based gene therapy research3.1%
  • その他56.5%

共著者

全論文

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  1. Clinical translation of nanomedicines: Challenges, opportunities, and keys

    著者: Mahmoud A. Younis, Hesham M. Tawfeek, Ahmed A. H. Abdellatif, Jelan A. Abdel-Aleem, Hideyoshi Harashima - Advanced Drug Delivery Reviews 2021 被引用: 392

  2. STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation

    著者: Takashi Nakamura, Takanori Sato, Rikito Endo, Shun Sasaki, Naomichi Takahashi, Yusuke Sato, Mamoru Hyodo, Yoshihiro Hayakawa, Hideyoshi Harashima - Journal for ImmunoTherapy of Cancer 2021 被引用: 251

  3. The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution

    著者: Takashi Nakamura, Minori Kawai, Yusuke Sato, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima - Molecular Pharmaceutics 2020 被引用: 178

  4. Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines

    著者: Takashi Nakamura, Yusuke Sato, Yuma Yamada, Mahmoud M. Abd Elwakil, Seigo Kimura, Mahmoud A. Younis, Hideyoshi Harashima - Advanced Drug Delivery Reviews 2022 被引用: 116

  5. Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo

    著者: Yusuke Sato, Kazuki Hashiba, Kosuke Sasaki, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima - Journal of Controlled Release 2019 被引用: 175

  6. Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA

    著者: Kazuki Hashiba, Yusuke Sato, Masamitsu Taguchi, Sachiko Sakamoto, Ayaka Otsu, Yoshiki Maeda, Takuya Shishido, Masao Murakawa, Okazaki Arimichi, Hideyoshi Harashima - Small Science 2022 被引用: 78

  7. The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors

    著者: Hiroto Hatakeyama, Hidetaka Akita, Hideyoshi Harashima - Biological and Pharmaceutical Bulletin 2013 被引用: 484

  8. Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers

    著者: Masatoshi Maeki, Yuka FUJISHIMA, Yusuke Sato, Takao Yasui, Noritada Kaji, Akihiko Ishida, Hirofumi Tani, Yoshinobu Baba, Hideyoshi Harashima, Manabu Tokeshi - PLoS ONE 2017 被引用: 187

  9. Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems

    著者: Masatoshi Maeki, Niko Kimura, Yusuke Sato, Hideyoshi Harashima, Manabu Tokeshi - Advanced Drug Delivery Reviews 2018 被引用: 308

  10. Ultra-small lipid nanoparticles encapsulating sorafenib and midkine-siRNA selectively-eradicate sorafenib-resistant hepatocellular carcinoma in vivo

    著者: Mahmoud A. Younis, Ikramy A. Khalil, Yaser Hosny Ali Elewa, Yasuhiro Kon, Hideyoshi Harashima - Journal of Controlled Release 2021 被引用: 115

  11. On the size-regulation of RNA-loaded lipid nanoparticles synthesized by microfluidic device

    著者: Kento Okuda, Yusuke Sato, Kazuki Iwakawa, Kosuke Sasaki, Nana Okabe, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima - Journal of Controlled Release 2022 被引用: 88

  12. Endocytosis of Gene Delivery Vectors: From Clathrin-dependent to Lipid Raft-mediated Endocytosis

    著者: Ayman El‐Sayed, Hideyoshi Harashima - Molecular Therapy 2013 被引用: 344

  13. The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability, and Safety of Lipid‐Based Nanoparticles for mRNA and DNA Delivery

    著者: Konstantinos N. Kafetzis, Natalia Papalamprou, Elisha McNulty, Kai Xin Thong, Yusuke Sato, Mironov Aa, Atul Purohit, Philip J. Welsby, Hideyoshi Harashima, Cynthia Yu‐Wai‐Man, Aristides D. Tagalakis - Advanced Healthcare Materials 2023 被引用: 83

  14. mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines

    著者: Ryoya Shimosakai, Ikramy A. Khalil, Seigo Kimura, Hideyoshi Harashima - Pharmaceuticals 2022 被引用: 53

  15. Challenges in Promoting Mitochondrial Transplantation Therapy

    著者: Yuma Yamada, Momo Ito, Manae Arai, Mitsue Hibino, Takao Tsujioka, Hideyoshi Harashima - International Journal of Molecular Sciences 2020 被引用: 106

  16. Overcoming thermostability challenges in mRNA–lipid nanoparticle systems with piperidine-based ionizable lipids

    著者: Kazuki Hashiba, Masamitsu Taguchi, Sachiko Sakamoto, Ayaka Otsu, Yoshiki Maeda, Hirofumi Ebe, Okazaki Arimichi, Hideyoshi Harashima, Yusuke Sato - Communications Biology 2024 被引用: 71

  17. Development of the iLiNP Device: Fine Tuning the Lipid Nanoparticle Size within 10 nm for Drug Delivery

    著者: Niko Kimura, Masatoshi Maeki, Yusuke Sato, Yusuke Note, Akihiko Ishida, Hirofumi Tani, Hideyoshi Harashima, Manabu Tokeshi - ACS Omega 2018 被引用: 216

  18. Manipulating the function of tumor-associated macrophages by siRNA-loaded lipid nanoparticles for cancer immunotherapy

    著者: Nour Shobaki, Yusuke Sato, Yuichi Suzuki, Nana Okabe, Hideyoshi Harashima - Journal of Controlled Release 2020 被引用: 111

  19. A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma

    著者: Hiroto Hatakeyama, Hidetaka Akita, Hideyoshi Harashima - Advanced Drug Delivery Reviews 2010 被引用: 640

  20. Different kinetics for the hepatic uptake of lipid nanoparticles between the apolipoprotein E/low density lipoprotein receptor and the N-acetyl-d-galactosamine/asialoglycoprotein receptor pathway

    著者: Yusuke Sato, Yoshiyuki Kinami, Kazuki Hashiba, Hideyoshi Harashima - Journal of Controlled Release 2020 被引用: 93

  21. Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery

    著者: Niko Kimura, Masatoshi Maeki, Yusuke Sato, Akihiko Ishida, Hirofumi Tani, Hideyoshi Harashima, Manabu Tokeshi - ACS Applied Materials & Interfaces 2020 被引用: 102

  22. Novel lipid combination for delivery of plasmid DNA to immune cells in the spleen

    著者: Seigo Kimura, Ikramy A. Khalil, Yaser Hosny Ali Elewa, Hideyoshi Harashima - Journal of Controlled Release 2021 被引用: 81

  23. mRNA-Loaded Lipid Nanoparticles Targeting Dendritic Cells for Cancer Immunotherapy

    著者: Kosuke Sasaki, Yusuke Sato, Kento Okuda, Kazuki Iwakawa, Hideyoshi Harashima - Pharmaceutics 2022 被引用: 67

  24. Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma

    著者: Takashi Nakamura, Hiroko Miyabe, Mamoru Hyodo, Yusuke Sato, Yoshihiro Hayakawa, Hideyoshi Harashima - Journal of Controlled Release 2015 被引用: 198