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Hiroaki Mitsuya

1978–2024 年に発表

143
論文数
25,609
被引用数
88
h 指数
141
i10 指数

被引用数

Hiroaki Mitsuya の年別被引用数1979 年: 被引用 1 件1980 年: 被引用 2 件1982 年: 被引用 6 件1983 年: 被引用 3 件1984 年: 被引用 5 件1985 年: 被引用 13 件1986 年: 被引用 39 件1987 年: 被引用 165 件1988 年: 被引用 146 件1989 年: 被引用 193 件1990 年: 被引用 231 件1991 年: 被引用 178 件1992 年: 被引用 239 件1993 年: 被引用 145 件1994 年: 被引用 135 件1995 年: 被引用 108 件1996 年: 被引用 94 件1997 年: 被引用 87 件1998 年: 被引用 110 件1999 年: 被引用 89 件2000 年: 被引用 89 件2001 年: 被引用 86 件2002 年: 被引用 104 件2003 年: 被引用 100 件2004 年: 被引用 150 件2005 年: 被引用 102 件2006 年: 被引用 120 件2007 年: 被引用 108 件2008 年: 被引用 108 件2009 年: 被引用 132 件2010 年: 被引用 84 件2011 年: 被引用 96 件2012 年: 被引用 81 件2013 年: 被引用 90 件2014 年: 被引用 63 件2015 年: 被引用 74 件2016 年: 被引用 64 件2017 年: 被引用 37 件2018 年: 被引用 49 件2019 年: 被引用 207 件2020 年: 被引用 304 件2021 年: 被引用 588 件2022 年: 被引用 699 件2023 年: 被引用 340 件2024 年: 被引用 378 件2025 年: 被引用 103 件2026 年: 被引用 11 件1981 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 2,354 件、この内訳の 36.2%日本: 引用元論文 421 件、この内訳の 6.5%中国: 引用元論文 414 件、この内訳の 6.4%イギリス: 引用元論文 358 件、この内訳の 5.5%ドイツ: 引用元論文 309 件、この内訳の 4.7%フランス: 引用元論文 273 件、この内訳の 4.2%イタリア: 引用元論文 191 件、この内訳の 2.9%ベルギー: 引用元論文 185 件、この内訳の 2.8%インド: 引用元論文 161 件、この内訳の 2.5%カナダ: 引用元論文 147 件、この内訳の 2.3%スペイン: 引用元論文 136 件、この内訳の 2.1%オーストラリア: 引用元論文 116 件、この内訳の 1.8%
0%36.2%その他 22.1%

機関

分野

  • Medicine53%
  • Immunology and Microbiology21.1%
  • Biochemistry, Genetics and Molecular Biology14.9%
  • Computer Science3.8%
  • Chemistry2.5%
  • Pharmacology, Toxicology and Pharmaceutics1%
  • その他3.7%

トピック

  • HIV Research and Treatment9.9%
  • HIV/AIDS drug development and treatment8.6%
  • SARS-CoV-2 and COVID-19 Research7.8%
  • COVID-19 Clinical Research Studies4.6%
  • HIV/AIDS Research and Interventions2.9%
  • Computational Drug Discovery Methods2.4%
  • その他63.8%

共著者

全論文

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  1. Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development

    著者: Masaki Imai, Kiyoko Iwatsuki‐Horimoto, Masato Hatta, Samantha Loeber, Peter Halfmann, Noriko Nakajima, Tokiko Watanabe, Michiko Ujie, Kenta Takahashi, Mutsumi Ito, Shinya Yamada, Shufang Fan, S. Chiba, Makoto Kuroda, Lizheng Guan, K. Takada, Tammy Armbrust, Aaron Balogh, Yuri Furusawa, Moe Okuda, Hiroshi Ueki, Atsuhiro Yasuhara, Yuko Sakai‐Tagawa, Tiago J. S. Lopes, Maki Kiso, Seiya Yamayoshi, Noriko Kinoshita, Norio Ohmagari, Shin-ichiro Hattori, Makoto Takeda, Hiroaki Mitsuya, Florian Krammer, Tadaki Suzuki, Yoshihiro Kawaoka - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 被引用: 1,169

  2. Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA.2

    著者: Ryuta Uraki, Maki Kiso, Shun Iida, Masaki Imai, Emi Takashita, Makoto Kuroda, Peter Halfmann, Samantha Loeber, Tadashi Maemura, Seiya Yamayoshi, Seiichiro Fujisaki, Zhongde Wang, Mutsumi Ito, Michiko Ujie, Kiyoko Iwatsuki‐Horimoto, Yuri Furusawa, Ryan Wright, Zhenlu Chong, Seiya Ozono, Atsuhiro Yasuhara, Hiroshi Ueki, Yuko Sakai‐Tagawa, Rong Li, Yanan Liu, Deanna Larson, Michiko Koga, Takeya Tsutsumi, Eisuke Adachi, Makoto Saito, Shinya Yamamoto, Masao Hagihara, Keiko Mitamura, Tetsuro Sato, Masayuki Hojo, Shin-ichiro Hattori, Kenji Maeda, Riccardo Valdez, IASO study team, Pamela Bennett-Baker, Zijin Chu, Dawson Davis, Theresa Kowalski-Dobson, Ashley Eckard, Carmen Gherasim, Wolf Gremel, Kathleen Lindsey, David M. Manthei, Alyssa Meyers, Julio Zuniga Moya, Aaron Rico, Emily Stoneman, Victoria M. Blanc, Savanna Sneeringer, Lauren Warsinske, Moe Okuda, Jurika Murakami, Calvin Duong, Sucheta Godbole, Daniel C. Douek, Ken Maeda, Shinji Watanabe, Aubree Gordon, Norio Ohmagari, Hiroshi Yotsuyanagi, Michael Diamond, Hideki Hasegawa, Hiroaki Mitsuya, Tadaki Suzuki, Yoshihiro Kawaoka - Nature 2022 被引用: 292

  3. Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant

    著者: Emi Takashita, Noriko Kinoshita, Seiya Yamayoshi, Yuko Sakai-Tagawa, Seiichiro Fujisaki, Mutsumi Ito, Kiyoko Iwatsuki-Horimoto, Shiho Chiba, Peter Halfmann, Hiroyuki Nagai, Makoto Saito, Eisuke Adachi, David Sullivan, Andrew Pekosz, Shinji Watanabe, Kenji Maeda, Masaki Imai, Hiroshi Yotsuyanagi, Hiroaki Mitsuya, Norio Ohmagari, Makoto Takeda, Hideki Hasegawa, Yoshihiro Kawaoka - New England Journal of Medicine 2022 被引用: 404

  4. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

    著者: Shin-ichiro Hattori, Nobuyo Higashi‐Kuwata, Hironori Hayashi, Srinivasa Rao Allu, Jakka Raghavaiah, Haydar Bulut, Debananda Das, Brandon J. Anson, Emma K. Lendy, Yuki Takamatsu, Nobutoki Takamune, Naoki Kishimoto, Kazutaka Murayama, Kazuya Hasegawa, Mi Li, David A. Davis, Eiichi Kodama, Robert Yarchoan, Alexander Wlodawer, Shogo Misumi, Andrew D. Mesecar, Arun K. Ghosh, Hiroaki Mitsuya - Nature Communications 2021 被引用: 192

  5. Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2

    著者: Emi Takashita, Noriko Kinoshita, Seiya Yamayoshi, Yuko Sakai-Tagawa, Seiichiro Fujisaki, Mutsumi Ito, Kiyoko Iwatsuki-Horimoto, Peter Halfmann, Shinji Watanabe, Kenji Maeda, Masaki Imai, Hiroaki Mitsuya, Norio Ohmagari, Makoto Takeda, Hideki Hasegawa, Yoshihiro Kawaoka - New England Journal of Medicine 2022 被引用: 292

  6. Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure–Activity Relationship, and X-ray Structural Studies

    著者: Arun K. Ghosh, Jakka Raghavaiah, Dana Shahabi, Monika Yadav, Brandon J. Anson, Emma K. Lendy, Shin-ichiro Hattori, Nobuyo Higashi‐Kuwata, Hiroaki Mitsuya, Andrew D. Mesecar - Journal of Medicinal Chemistry 2021 被引用: 90

  7. Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis

    著者: Nobuyo Higashi‐Kuwata, Masatoshi Jinnin, Takamitsu Makino, Satoshi Fukushima, Yuji Inoue, Faith C. Muchemwa, Yuji Yonemura, Yoshihiro Komohara, Motohiro Takeya, Hiroaki Mitsuya, Hironobu Ihn - Arthritis Research & Therapy 2010 被引用: 246

  8. Recent Drug Development and Medicinal Chemistry Approaches for the Treatment of SARS‐CoV‐2 Infection and COVID‐19

    著者: Arun K. Ghosh, Jennifer L. Mishevich, Andrew D. Mesecar, Hiroaki Mitsuya - ChemMedChem 2022 被引用: 48

  9. 4′-Ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) Inhibits HIV-1 Reverse Transcriptase with Multiple Mechanisms

    著者: Eleftherios Michailidis, Andrew D. Huber, Emily Ryan, Yee Tsuey Ong, Maxwell D. Leslie, Kayla B. Matzek, Kamalendra Singh, Bruno Marchand, Ariel N. Hagedorn, Karen A. Kirby, Lisa C. Rohan, Eiichi Kodama, Hiroaki Mitsuya, Michael A. Parniak, Stefan G. Sarafianos - Journal of Biological Chemistry 2014 被引用: 118

  10. Identification of SARS-CoV-2 Mpro inhibitors containing P1’ 4-fluorobenzothiazole moiety highly active against SARS-CoV-2

    著者: Nobuyo Higashi‐Kuwata, Kohei Tsuji, Hironori Hayashi, Haydar Bulut, Maki Kiso, Masaki Imai, Hiromi Ogata-Aoki, Takahiro Ishii, Takuya Kobayakawa, Kenta Nakano, Nobutoki Takamune, Naoki Kishimoto, Shin-ichiro Hattori, Debananda Das, Yukari Uemura, Yosuke Shimizu, Manabu Aoki, Kazuya Hasegawa, Satoshi Suzuki, Akie Nishiyama, Junji Saruwatari, Yukiko Shimizu, Yoshikazu Sukenaga, Yuki Takamatsu, K. Tsuchiya, Kenji Maeda, Kazuhisa Yoshimura, Shun Iida, Seiya Ozono, Tadaki Suzuki, Tadashi Okamura, Shogo Misumi, Yoshihiro Kawaoka, Hirokazu Tamamura, Hiroaki Mitsuya - Nature Communications 2023 被引用: 45

  11. PDK1 inhibition is a novel therapeutic target in multiple myeloma

    著者: Saori Fujiwara, Yawara Kawano, Hiromichi Yuki, Yutaka Okuno, Kisato Nosaka, Hiroaki Mitsuya, Hironobu Hata - British Journal of Cancer 2012 被引用: 139

  12. Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA)

    著者: Zhe Salie, Karen A. Kirby, Eleftherios Michailidis, Bruno Marchand, Kamalendra Singh, Lisa C. Rohan, Eiichi Kodama, Hiroaki Mitsuya, Michael A. Parniak, Stefan G. Sarafianos - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 110

  13. Comparison of Rapid Antigen Tests for COVID-19

    著者: Seiya Yamayoshi, Yuko Sakai‐Tagawa, Michiko Koga, Osamu Akasaka, Ichiro Nakachi, Hidefumi Koh, Kenji Maeda, Eisuke Adachi, Makoto Saito, Hiroyuki Nagai, Kazuhiko Ikeuchi, Takayuki Ogura, Rie Baba, Kensuke Fujita, Takahiro Fukui, Fumimaro Ito, Shin-ichiro Hattori, Kei Yamamoto, Takato Nakamoto, Yuri Furusawa, Atsuhiro Yasuhara, Michiko Ujie, Shinya Yamada, Mutsumi Ito, Hiroaki Mitsuya, Norio Omagari, Hiroshi Yotsuyanagi, Kiyoko Iwatsuki‐Horimoto, Masaki Imai, Yoshihiro Kawaoka - Viruses 2020 被引用: 226

  14. Antibody titers against SARS-CoV-2 decline, but do not disappear for several months

    著者: Seiya Yamayoshi, Atsuhiro Yasuhara, Mutsumi Ito, Osamu Akasaka, Morio Nakamura, Ichiro Nakachi, Michiko Koga, Keiko Mitamura, Kazuma Yagi, Kenji Maeda, Hideaki Kato, Masanori Nojima, David Pattinson, Takayuki Ogura, Rie Baba, Kensuke Fujita, Hiroyuki Nagai, Shinya Yamamoto, Makoto Saito, Eisuke Adachi, Junichi Ochi, Shin-ichiro Hattori, Tetsuya Suzuki, Yusuke Miyazato, S. Chiba, Moe Okuda, Jurika Murakami, Taiki Hamabata, Kiyoko Iwatsuki‐Horimoto, Hideaki Nakajima, Hiroaki Mitsuya, Norio Omagari, Norio Sugaya, Hiroshi Yotsuyanagi, Yoshihiro Kawaoka - EClinicalMedicine 2021 被引用: 169

  15. GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

    著者: Shin-ichiro Hattori, Nobuyo Higshi-Kuwata, Jakka Raghavaiah, Debananda Das, Haydar Bulut, David A. Davis, Yuki Takamatsu, Kouki Matsuda, Nobutoki Takamune, Naoki Kishimoto, Tadashi Okamura, Shogo Misumi, Robert Yarchoan, Kenji Maeda, Arun K. Ghosh, Hiroaki Mitsuya - mBio 2020 被引用: 79

  16. Droplet digital PCR assay provides intrahepatic HBV cccDNA quantification tool for clinical application

    著者: Sanae Hayashi, Masanori Isogawa, Keigo Kawashima, Kyoko Ito, Natthaya Chuaypen, Yuji Morine, Mitsuo Shimada, Nobuyo Higashi‐Kuwata, Takehisa Watanabe, Pisit Tangkijvanich, Hiroaki Mitsuya, Yasuhito Tanaka - Scientific Reports 2022 被引用: 16

  17. 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

    著者: Hiroaki Mitsuya, Kent J. Weinhold, P A Furman, M H St Clair, Sandra Nusinoff Lehrman, Robert C. Gallo, Dani P. Bolognesi, David W. Barry, S Broder - National Academy of Sciences, Proceedings of the National Academy of Sciences 1985 被引用: 1,851

  18. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

    著者: P A Furman, James A. Fyfe, M H St Clair, Kent J. Weinhold, Janet L. Rideout, George A. Freeman, Sandra Nusinoff Lehrman, Dani P. Bolognesi, S Broder, Hiroaki Mitsuya - National Academy of Sciences, Proceedings of the National Academy of Sciences 1986 被引用: 1,349

  19. Diverse Transcriptional Response of CD4+ T Cells to Stromal Cell-Derived Factor (SDF)-1: Cell Survival Promotion and Priming Effects of SDF-1 on CD4+ T Cells

    著者: Yasuhiro Suzuki, Monzur Rahman, Hiroaki Mitsuya - The Journal of Immunology 2001 被引用: 177

  20. Mechanism of Inhibition of HIV-1 Reverse Transcriptase by 4′-Ethynyl-2-fluoro-2′-deoxyadenosine Triphosphate, a Translocation-defective Reverse Transcriptase Inhibitor

    著者: Eleftherios Michailidis, Bruno Marchand, Eiichi Kodama, Kamlendra Singh, Masao Matsuoka, Karen A. Kirby, Emily Ryan, Ali M. Sawani, Éva Nagy, Noriyuki Ashida, Hiroaki Mitsuya, Michael A. Parniak, Stefan G. Sarafianos - Journal of Biological Chemistry 2009 被引用: 138

  21. 2′-Deoxy-4′-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants

    著者: Atsushi Kawamoto, Eiichi Kodama, Stefan G. Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroaki Mitsuya, Eddy Arnold, Masao Matsuoka - The International Journal of Biochemistry & Cell Biology 2008 被引用: 125

  22. Structure–Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2-carbonyl Moieties

    著者: Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nobuyo Higashi‐Kuwata, Kouki Shinohara, Chika Azuma, Yutaro Miura, Hiroki Nakano, Naoya Wada, Shin‐ichiro Hattori, Haydar Bulut, Hiroaki Mitsuya, Hirokazu Tamamura - Journal of Medicinal Chemistry 2023 被引用: 24

  23. Novel bis -Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human Immunodeficiency Virus In Vitro

    著者: Yasuhiro Koh, Hirotomo Nakata, Kenji Maeda, Hiromi Ogata, Geoffrey Bilcer, Thippeswamy Devasamudram, John Kincaid, Péter Boross, Yuan-Fang Wang, Yunfeng Tie, Patra Volarath, L. Gaddis, Robert W. Harrison, Irene T. Weber, Arun K. Ghosh, Hiroaki Mitsuya - Antimicrobial Agents and Chemotherapy 2003 被引用: 366

  24. Kinetic Characterization and Cross-Resistance Patterns Of HIV-1 Protease Mutants Selected under Drug Pressure

    著者: Sergei Gulnik, Leonid I. Suvorov, Beishan Liu, Betty Yu, Barry Anderson, Hiroaki Mitsuya, John W. Erickson - Biochemistry 1995 被引用: 266