Hiroshi Maeda
1955–2025 年に発表
- 別表記
- Hiroshi Maéda
- 308
- 論文数
- 67,798
- 被引用数
- 114
- h 指数
- 222
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology26.1%
- Medicine23.3%
- Materials Science22.5%
- Engineering11.1%
- Agricultural and Biological Sciences4%
- Immunology and Microbiology2.9%
- その他10.1%
トピック
- Nanoparticle-Based Drug Delivery10.2%
- Nanoplatforms for cancer theranostics7.2%
- RNA Interference and Gene Delivery5.5%
- Advanced biosensing and bioanalysis techniques3%
- Photodynamic Therapy Research Studies1.3%
- Nitric Oxide and Endothelin Effects1.1%
- その他71.7%
共著者
- Takaaki Akaike50
- Jun Fang30
- Norikazu Ikoma20
- Hideaki Kawano19
- Tomohiro Sawa19
- Kazuya Tomiura13
- Hideaki Orii12
- Khaled Greish12
- Naoki Higashinaka10
- Huili Chen9
- Jianming Jin9
- Yoichi Miyamoto9
- Hideaki Nakamura8
- Tatsuya Okamoto8
- Hiroyuki Terashima7
- Jun Wu7
- Keizo Sato7
- Kiyotoshi Yasumoto7
- Natalia Dudareva7
- Toshimitsu Konno7
- Yasuhiro Matsumura7
- Keisuke Haari6
- Xiang Zheng Meng6
- Yongmei Zhang6
全論文
- A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.
著者: Yasuhiro Matsumura, Hiroshi Maeda - 1986 被引用: 6,798
- Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
著者: Hiroshi Maeda, Jun Wu, Tomohiro Sawa, Yasuhiro Matsumura, K. Hori - Journal of Controlled Release 2000 被引用: 6,505
- The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
著者: Jun Fang, Hideaki Nakamura, Hiroshi Maeda - Advanced Drug Delivery Reviews 2010 被引用: 3,500
- Exploiting the dynamics of the EPR effect and strategies to improve the therapeutic effects of nanomedicines by using EPR effect enhancers
著者: Jun Fang, Waliul Islam, Hiroshi Maeda - Advanced Drug Delivery Reviews 2020 被引用: 724
- The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo
著者: Hiroshi Maeda, Hideaki Nakamura, Jun Fang - Advanced Drug Delivery Reviews 2012 被引用: 2,347
- The Shikimate Pathway and Aromatic Amino Acid Biosynthesis in Plants
著者: Hiroshi Maéda, Natalia Dudareva - Annual Review of Plant Biology 2012 被引用: 1,539
- Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity
著者: Hiroshi Maeda - Advanced Drug Delivery Reviews 2015 被引用: 1,161
- Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology
著者: Uma Prabhakar, Hiroshi Maeda, Rakesh K. Jain, Eva M. Sevick‐Muraca, William C. Zamboni, Omid C. Farokhzad, Simon T. Barry, Alberto Gabizón, Piotr Grodzinski, David C. Blakey - Cancer Research 2013 被引用: 1,465
- The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting
著者: Hiroshi Maeda - Advances in Enzyme Regulation 2001 被引用: 2,463
- Analyses of repeated failures in cancer therapy for solid tumors: poor tumor‐selective drug delivery, low therapeutic efficacy and unsustainable costs
著者: Hiroshi Maeda, Mahin Khatami - Clinical and Translational Medicine 2018 被引用: 486
- Exploiting the enhanced permeability and retention effect for tumor targeting
著者: Arun K. Iyer, Khaled Greish, Jun Fang, Hiroshi Maeda - Drug Discovery Today 2006 被引用: 1,827
- Macromolecular therapeutics in cancer treatment: The EPR effect and beyond
著者: Hiroshi Maeda - Journal of Controlled Release 2012 被引用: 795
- Tyrosine biosynthesis, metabolism, and catabolism in plants
著者: Craig A. Schenck, Hiroshi Maéda - Phytochemistry 2018 被引用: 282
- Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects
著者: Hiroshi Maeda - Bioconjugate Chemistry 2010 被引用: 979
- Evolutionary History of Plant Metabolism
著者: Hiroshi Maéda, Alisdair R. Fernie - Annual Review of Plant Biology 2021 被引用: 126
- Genome sequencing and analysis of Aspergillus oryzae
著者: Masayuki Machida, Kiyoshi Asai, Motoaki Sano, Toshihiro Tanaka, Toshitaka Kumagai, Goro Terai, Ken-Ichi Kusumoto, Toshihide Arima, Osamu Akita, Yutaka Kashiwagi, Keietsu Abe, Katsuya Gomi, Hiroyuki Horiuchi, Katsuhiko Kitamoto, Tetsuo Kobayashi, Michio Takeuchi, David W. Denning, James E. Galagan, William C. Nierman, Jiujiang Yu, David B. Archer, Joan W. Bennett, Deepak Bhatnagar, Thomas E. Cleveland, Natalie D. Fedorova, Osamu Gotoh, Hiroshi Horikawa, Akira Hosoyama, Masayuki Ichinomiya, Rie Igarashi, Kazuhiro Iwashita, Praveen R. Juvvadi, Masashi Kato, Yumiko Kato, Taishin Kin, Akira Kokubun, Hiroshi Maéda, Noriko Maeyama, Jun-ichi Maruyama, Hideki Nagasaki, Tasuku Nakajima, Ken Oda, Kinya Okada, Ian T. Paulsen, Kazutoshi Sakamoto, Toshihiko Sawano, Mikio Takahashi, Kumiko Takase, Yasunobu Terabayashi, Jennifer R. Wortman, Osamu Yamada, Youhei Yamagata, Hideharu Anazawa, Yoji Hata, Yoshinao Koide, Takashi Komori, Yasuji Koyama, Toshitaka Minetoki, Sivasundaram Suharnan, Akimitsu Tanaka, Katsumi Isono, Satoru Kuhara, Naotake Ogasawara, Hisashi Kikuchi - Nature 2005 被引用: 1,266
- Therapeutic strategies by modulating oxygen stress in cancer and inflammation
著者: Jun Fang, Takahiro Seki, Hiroshi Maeda - Advanced Drug Delivery Reviews 2009 被引用: 542
- The entry reaction of the plant shikimate pathway is subjected to highly complex metabolite-mediated regulation
著者: Ryo Yokoyama, Marcos V. V. de Oliveira, Bailey Kleven, Hiroshi Maéda - The Plant Cell 2020 被引用: 119
- Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
著者: Hiroshi Maeda, Tomohiro Sawa, Toshimitsu Konno - Journal of Controlled Release 2001 被引用: 916
- An alternative pathway contributes to phenylalanine biosynthesis in plants via a cytosolic tyrosine:phenylpyruvate aminotransferase
著者: Heejin Yoo, Joshua R. Widhalm, Yichun Qian, Hiroshi Maéda, Bruce R. Cooper, Amber S. Jannasch, Itay Gonda, Efraim Lewinsohn, David Rhodes, Natalia Dudareva - Nature Communications 2013 被引用: 241
- Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
著者: Hiroshi Maeda, Gahininath Y. Bharate, Jurstine Daruwalla - European Journal of Pharmaceutics and Biopharmaceutics 2008 被引用: 1,153
- The 35th Anniversary of the Discovery of EPR Effect: A New Wave of Nanomedicines for Tumor-Targeted Drug Delivery—Personal Remarks and Future Prospects
著者: Hiroshi Maeda - Journal of Personalized Medicine 2021 被引用: 151
- Evolutionary origin and functional diversification of aminotransferases
著者: Kaan Koper, Sang‐Woo Han, Delia Casas‐Pastor, Yasuo Yoshikuni, Hiroshi Maéda - Journal of Biological Chemistry 2022 被引用: 88
- Factors affecting the dynamics and heterogeneity of the EPR effect: pathophysiological and pathoanatomic features, drug formulations and physicochemical factors
著者: Rayhanul Islam, Hiroshi Maeda, Jun Fang - Expert Opinion on Drug Delivery 2021 被引用: 84
