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Hiroyuki Mano

1987–2025 年に発表

139
論文数
27,221
被引用数
81
h 指数
131
i10 指数

被引用数

Hiroyuki Mano の年別被引用数1967 年: 被引用 1 件1981 年: 被引用 1 件1987 年: 被引用 2 件1988 年: 被引用 7 件1989 年: 被引用 7 件1990 年: 被引用 1 件1991 年: 被引用 6 件1992 年: 被引用 4 件1993 年: 被引用 17 件1994 年: 被引用 45 件1995 年: 被引用 73 件1996 年: 被引用 79 件1997 年: 被引用 76 件1998 年: 被引用 82 件1999 年: 被引用 96 件2000 年: 被引用 98 件2001 年: 被引用 68 件2002 年: 被引用 81 件2003 年: 被引用 72 件2004 年: 被引用 80 件2005 年: 被引用 64 件2006 年: 被引用 56 件2007 年: 被引用 79 件2008 年: 被引用 118 件2009 年: 被引用 187 件2010 年: 被引用 190 件2011 年: 被引用 335 件2012 年: 被引用 413 件2013 年: 被引用 403 件2014 年: 被引用 336 件2015 年: 被引用 292 件2016 年: 被引用 264 件2017 年: 被引用 211 件2018 年: 被引用 263 件2019 年: 被引用 681 件2020 年: 被引用 679 件2021 年: 被引用 803 件2022 年: 被引用 699 件2023 年: 被引用 595 件2024 年: 被引用 916 件2025 年: 被引用 508 件2026 年: 被引用 15 件1968〜1980 年は被引用が無いため表示していません1982〜1986 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 2,998 件、この内訳の 26.8%中国: 引用元論文 1,618 件、この内訳の 14.4%日本: 引用元論文 1,035 件、この内訳の 9.2%イギリス: 引用元論文 573 件、この内訳の 5.1%ドイツ: 引用元論文 523 件、この内訳の 4.7%イタリア: 引用元論文 441 件、この内訳の 3.9%フランス: 引用元論文 385 件、この内訳の 3.4%カナダ: 引用元論文 293 件、この内訳の 2.6%オーストラリア: 引用元論文 265 件、この内訳の 2.4%オランダ: 引用元論文 244 件、この内訳の 2.2%スペイン: 引用元論文 233 件、この内訳の 2.1%韓国: 引用元論文 227 件、この内訳の 2%
0%26.8%その他 21.2%

機関

分野

  • Medicine55.9%
  • Biochemistry, Genetics and Molecular Biology32.4%
  • Immunology and Microbiology7.5%
  • Engineering1.1%
  • Neuroscience0.8%
  • Agricultural and Biological Sciences0.5%
  • その他1.8%

トピック

  • Lung Cancer Treatments and Mutations7.4%
  • Lung Cancer Research Studies3.6%
  • Cancer Genomics and Diagnostics3.6%
  • Cancer Immunotherapy and Biomarkers3.4%
  • Acute Myeloid Leukemia Research2.1%
  • Immune Cell Function and Interaction2.1%
  • その他77.8%

共著者

全論文

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  1. Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

    著者: Shogo Kumagai, Shohei Koyama, Kota Itahashi, Tokiyoshi Tanegashima, Yi-Tzu Lin, Yosuke Togashi, Takahiro Kamada, Takuma Irie, Genki Okumura, Hidetoshi Kono, Daisuke Ito, Rika Fujii, Sho Watanabe, Atsuo Sai, Shota Fukuoka, Eri Sugiyama, Go Watanabe, Takuya Owari, Hitomi Nishinakamura, Daisuke Sugiyama, Yuka Maeda, Akihito Kawazoe, Hiroki Yukami, Keigo Chida, Yuuki Ohara, Tatsuya Yoshida, Yuki Shinno, Yuki Takeyasu, Masayuki Shirasawa, Kenta Nakama, Keiju Aokage, Jun Suzuki, Genichiro Ishii, Takeshi Kuwata, Naoya Sakamoto, Masahito Kawazu, Toshihide Ueno, Taisuke Mori, Naoya Yamazaki, Masahiro Tsuboi, Yasushi Yatabe, Takahiro Kinoshita, Toshihiko Doi, Kohei Shitara, Hiroyuki Mano, Hiroyoshi Nishikawa - Cancer Cell 2022 被引用: 838

  2. The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

    著者: Shogo Kumagai, Yosuke Togashi, Takahiro Kamada, Eri Sugiyama, Hitomi Nishinakamura, Yoshiko Takeuchi, Vitaly Kochin, Kota Itahashi, Yuka Maeda, Shigeyuki Matsui, Takuma Shibahara, Yasuho Yamashita, Takuma Irie, Ayaka Tsuge, Shota Fukuoka, Akihito Kawazoe, Hibiki Udagawa, Keisuke Kirita, Keiju Aokage, Genichiro Ishii, Takeshi Kuwata, Kenta Nakama, Masahito Kawazu, Toshihide Ueno, Naoya Yamazaki, Kōichi Goto, Masahiro Tsuboi, Hiroyuki Mano, Toshihiko Doi, Kohei Shitara, Hiroyoshi Nishikawa - Nature Immunology 2020 被引用: 812

  3. Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer

    著者: Manabu Soda, Young Lim Choi, Munehiro Enomoto, Shuji Takada, Yoshihiro Yamashita, Shunpei Ishikawa, Shin‐ichiro Fujiwara, Hideki Watanabe, Kentaro Kurashina, Hisashi Hatanaka, Masashi Bando, Shoji Ohno, Yuichi Ishikawa, Hiroyuki Aburatani, Toshiro Niki, Yasunori Sohara, Yukihiko Sugiyama, Hiroyuki Mano - Nature 2007 被引用: 5,456

  4. An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells

    著者: Shogo Kumagai, Yosuke Togashi, Chika Sakai, Akihito Kawazoe, Masahito Kawazu, Toshihide Ueno, Eiichi Sato, Takeshi Kuwata, Takahiro Kinoshita, Masami Yamamoto, Sachiyo Nomura, Tetsuya Tsukamoto, Hiroyuki Mano, Kohei Shitara, Hiroyoshi Nishikawa - Immunity 2020 被引用: 259

  5. Immune evasion through mitochondrial transfer in the tumour microenvironment

    著者: Hideki Ikeda, Katsushige Kawase, Tatsuya Nishi, Tomofumi Watanabe, Keizo Takenaga, Takashi Inozume, Takamasa Ishino, Sho Aki, Jason Lin, Shusuke Kawashima, Joji Nagasaki, Youki Ueda, Shinichiro Suzuki, Hideki Makinoshima, Makiko Itami, Yuki Nakamura, Yasutoshi Tatsumi, Yusuke Suenaga, Takao Morinaga, Akiko Honobe‐Tabuchi, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yasuhiro Nakamura, Yukiko Kiniwa, Eiki Ichihara, Hidetoshi Hayashi, Jun‐ichiro Ikeda, Toyoyuki Hanazawa, Shinichi Toyooka, Hiroyuki Mano, Takuji Suzuki, Tsuyoshi Osawa, Masahito Kawazu, Yosuke Togashi - Nature 2025 被引用: 248

  6. RET, ROS1 and ALK fusions in lung cancer

    著者: Kengo Takeuchi, Manabu Soda, Yuki Togashi, Ritsuro Suzuki, Seiji Sakata, Satoko Hatano, Reimi Asaka, Wakako Hamanaka, Hironori Ninomiya, Hirofumi Uehara, Young Lim Choi, Yukitoshi Satoh, Sakae Okumura, Ken Nakagawa, Hiroyuki Mano, Yuichi Ishikawa - Nature Medicine 2012 被引用: 1,330

  7. C-CAT: The National Datacenter for Cancer Genomic Medicine in Japan

    著者: Takashi Kohno, Mamoru Kato, Shinji Kohsaka, Tomohisa Sudo, Ikuo Tamai, Yuichi Shiraishi, Yusuke Okuma, Daisuke Ogasawara, Tatsuya Suzuki, Teruhiko Yoshida, Hiroyuki Mano - Cancer Discovery 2022 被引用: 198

  8. PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes

    著者: Joji Nagasaki, Takashi Inozume, Nicolas Sax, Ryo Ariyasu, Masakazu Ishikawa, Kazuo Yamashita, Masahito Kawazu, Toshihide Ueno, Takuma Irie, Etsuko Tanji, Takao Morinaga, Akiko Honobe, Takehiro Ohnuma, Mitsuru Yoshino, Takekazu Iwata, Katsushige Kawase, Keita Sasaki, Toyoyuki Hanazawa, Vitaly Kochin, Tatsuyoshi Kawamura, Hiroyuki Matsue, Masayuki Hino, Hiroyuki Mano, Yutaka Suzuki, Hiroyoshi Nishikawa, Yosuke Togashi - Cell Reports 2022 被引用: 114

  9. Multi-omic profiling of peritoneal metastases in gastric cancer identifies molecular subtypes and therapeutic vulnerabilities

    著者: Yosuke Tanaka, Fumiko Chiwaki, Shinya Kojima, Masahito Kawazu, Masayuki Komatsu, Toshihide Ueno, Satoshi Inoue, Shigeki Sekine, Keisuke Matsusaki, Hiromichi Matsushita, Narikazu Boku, Yae Kanai, Yasushi Yatabe, Hiroki Sasaki, Hiroyuki Mano - Nature Cancer 2021 被引用: 92

  10. Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases

    著者: Jianfeng Li, Yuting Dai, Henrik Lilljebjörn, Shu-Hong Shen, Bo-Wen Cui, Ling Bai, Yuan-Fang Liu, Maoxiang Qian, Yasuo Kubota, Hitoshi Kiyoi, Itaru Matsumura, Yasushi Miyazaki, Linda Olsson, Ah Moy Tan, Hany Ariffin, Jing Chen, Junko Takita, Takahiko Yasuda, Hiroyuki Mano, Bertil Johansson, Jun J. Yang, Allen Eng Juh Yeoh, Fumihiko Hayakawa, Chen Zhu, Ching‐Hon Pui, Thoas Fioretos, Sai-Juan Chen, Jinyan Huang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 被引用: 321

  11. A Low Tumor Mutational Burden and PTEN Mutations Are Predictors of a Negative Response to PD-1 Blockade in MSI-H/dMMR Gastrointestinal Tumors

    著者: Keigo Chida, Akihito Kawazoe, Masahito Kawazu, Toshihiro Suzuki, Yoshiaki Nakamura, Tetsuya Nakatsura, Takeshi Kuwata, Toshihide Ueno, Yasutoshi Kuboki, Daisuke Kotani, Takashi Kojima, Hiroya Taniguchi, Hiroyuki Mano, Masafumi Ikeda, Kohei Shitara, Itaru Endo, Takayuki Yoshino - Clinical Cancer Research 2021 被引用: 113

  12. TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment

    著者: Shusuke Kawashima, Takashi Inozume, Masahito Kawazu, Toshihide Ueno, Joji Nagasaki, Etsuko Tanji, Akiko Honobe, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yasuhiro Nakamura, Tomonori Kawasaki, Yukiko Kiniwa, Osamu Yamasaki, Satoshi Fukushima, Yuzuru Ikehara, Hiroyuki Mano, Yutaka Suzuki, Hiroyoshi Nishikawa, Hiroyuki Matsue, Yosuke Togashi - Journal for ImmunoTherapy of Cancer 2021 被引用: 87

  13. Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations

    著者: Satoshi Inoue, Yasushi Hirota, Toshihide Ueno, Yamato Fukui, Emiko Yoshida, Takuo Hayashi, Shinya Kojima, Reina Takeyama, Taiki Hashimoto, Tohru Kiyono, Masako Ikemura, Ayumi Taguchi, Tomoki Tanaka, Yosuke Tanaka, Seiji Sakata, Kengo Takeuchi, Ayako Muraoka, Satoko Osuka, Tsuyoshi Saito, Katsutoshi Oda, Yutaka Osuga, Yasuhisa Terao, Masahito Kawazu, Hiroyuki Mano - Nature Communications 2019 被引用: 139

  14. EML4-ALK Mutations in Lung Cancer That Confer Resistance to ALK Inhibitors

    著者: Young Lim Choi, Manabu Soda, Yoshihiro Yamashita, Toshihide Ueno, Junpei Takashima, Takahiro Nakajima, Yasushi Yatabe, Kengo Takeuchi, Toru Hamada, Hidenori Haruta, Yuichi Ishikawa, Hideki Kimura, Tetsuya Mitsudomi, Yoshiro Tanio, Hiroyuki Mano - New England Journal of Medicine 2010 被引用: 1,181

  15. Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation

    著者: Keigo Morita, Yutaro Hama, Tamaki Izume, Norito Tamura, Toshihide Ueno, Yoshihiro Yamashita, Yuriko Sakamaki, Kaito Mimura, Hideaki Morishita, Wataru Shihoya, Osamu Nureki, Hiroyuki Mano, Noboru Mizushima - The Journal of Cell Biology 2018 被引用: 229

  16. Multicenter Phase I/II Trial of Napabucasin and Pembrolizumab in Patients with Metastatic Colorectal Cancer (EPOC1503/SCOOP Trial)

    著者: Akihito Kawazoe, Yasutoshi Kuboki, Eiji Shinozaki, Hiroki Hara, Tomohiro Nishina, Yoshito Komatsu, Satoshi Yuki, Masashi Wakabayashi, Shogo Nomura, Akihiro Sato, Takeshi Kuwata, Masahito Kawazu, Hiroyuki Mano, Yosuke Togashi, Hiroyoshi Nishikawa, Takayuki Yoshino - Clinical Cancer Research 2020 被引用: 100

  17. Transcriptomic Profiling of MSI-H/dMMR Gastrointestinal Tumors to Identify Determinants of Responsiveness to Anti–PD-1 Therapy

    著者: Keigo Chida, Akihito Kawazoe, Toshihiro Suzuki, Masahito Kawazu, Toshihide Ueno, Kazumasa Takenouchi, Yoshiaki Nakamura, Yasutoshi Kuboki, Daisuke Kotani, Takashi Kojima, Hideaki Bando, Saori Mishima, Takeshi Kuwata, Naoya Sakamoto, Jun Watanabe, Hiroyuki Mano, Masafumi Ikeda, Kohei Shitara, Itaru Endo, Tetsuya Nakatsura, Takayuki Yoshino - Clinical Cancer Research 2022 被引用: 63

  18. Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults

    著者: Takahiko Yasuda, Shinobu Tsuzuki, Masahito Kawazu, Fumihiko Hayakawa, Shinya Kojima, Toshihide Ueno, Naoto Imoto, Shinji Kohsaka, Akiko Kunita, Koichiro Doi, Toru Sakura, Toshiaki Yujiri, Eisei Kondo, Katsumichi Fujimaki, Yasunori Ueda, Yasutaka Aoyama, Shigeki Ohtake, Junko Takita, Eirin Sai, Masafumi Taniwaki, Mineo Kurokawa, Shinichi Morishita, Masashi Fukayama, Hitoshi Kiyoi, Yasushi Miyazaki, Tomoki Naoe, Hiroyuki Mano - Nature Genetics 2016 被引用: 271

  19. A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer

    著者: Shinji Kohsaka, Masaaki Nagano, Toshihide Ueno, Yoshiyuki Suehara, Takuo Hayashi, Naoko Shimada, Kazuhisa Takahashi, Kenji Suzuki, Kazuya Takamochi, Fumiyuki Takahashi, Hiroyuki Mano - Science Translational Medicine 2017 被引用: 212

  20. Multiomic molecular characterization of the response to combination immunotherapy in MSS/pMMR metastatic colorectal cancer

    著者: Shogo Takei, Yosuke Tanaka, Yi-Tzu Lin, Shohei Koyama, Shota Fukuoka, Hiroki Hara, Yoshiaki Nakamura, Yasutoshi Kuboki, Daisuke Kotani, Takashi Kojima, Hideaki Bando, Saori Mishima, Toshihide Ueno, Shinya Kojima, Masashi Wakabayashi, Naoya Sakamoto, Motohiro Kojima, Takeshi Kuwata, Takayuki Yoshino, Hiroyoshi Nishikawa, Hiroyuki Mano, Itaru Endo, Kohei Shitara, Akihito Kawazoe - Journal for ImmunoTherapy of Cancer 2024 被引用: 26

  21. Highly sensitive fusion detection using plasma cell‐free RNA in non‐small‐cell lung cancers

    著者: Nobuhiko Hasegawa, Shinji Kohsaka, Kana Kurokawa, Yuki Shinno, Ikuko Nakamura, Toshihide Ueno, Shinya Kojima, Masahito Kawazu, Yoshiyuki Suehara, Muneaki Ishijima, Yasushi Goto, Yuki Kojima, Kan Yonemori, Takuo Hayashi, Tsuyoshi Saito, Takehito Shukuya, Fumiyuki Takahashi, Kazuhisa Takahashi, Hiroyuki Mano - Cancer Science 2021 被引用: 49

  22. HLA Class I Analysis Provides Insight Into the Genetic and Epigenetic Background of Immune Evasion in Colorectal Cancer With High Microsatellite Instability

    著者: Masahito Kawazu, Toshihide Ueno, Koichi Saeki, Nicolas Sax, Yosuke Togashi, Takayuki Kanaseki, Keigo Chida, Fumishi Kishigami, Kazuhito Sato, Shinya Kojima, Masafumi Otsuka, Akihito Kawazoe, Hitomi Nishinakamura, Yuka Maeda, Yoko Yamamoto, Kazuo Yamashita, Satoshi Inoue, Tokiyoshi Tanegashima, Daisuke Matsubara, Kenta Tane, Yosuke Tanaka, Hisae Iinuma, Yojiro Hashiguchi, Shoichi Hazama, Seik‐Soon Khor, Katsushi Tokunaga, Masahiro Tsuboi, Toshiro Niki, Masatoshi Eto, Kohei Shitara, Toshihiko Torigoe, Soichiro Ishihara, Hiroyuki Aburatani, Hiroshi Haeno, Hiroyoshi Nishikawa, Hiroyuki Mano - Gastroenterology 2021 被引用: 53

  23. Oncogenic mutations of ALK kinase in neuroblastoma

    著者: Yuyan Chen, Junko Takita, Young Lim Choi, Motohiro Kato, Miki Ohira, Masashi Sanada, Lili Wang, Manabu Soda, Akira Kikuchi, Takashi Igarashi, Akira Nakagawara, Yasuhide Hayashi, Hiroyuki Mano, Seishi Ogawa - Nature 2008 被引用: 922

  24. A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer

    著者: King Pan Ng, Axel M. Hillmer, Charles Chuah, Wen Chun Juan, Tun Kiat Ko, Audrey S.M. Teo, Pramila Ariyaratne, Naoto Takahashi, Kenichi Sawada, Yao Fei, Sheila Soh, Wah Heng Lee, John W J Huang, John Carson Allen, Xing Yi Woo, Niranjan Nagarajan, Vikrant Kumar, Anbupalam Thalamuthu, Wan Ting Poh, Ai Leen Ang, Hae Tha Mya, Gee Fung How, Li Yi Yang, Liang Piu Koh, Balram Chowbay, Chia-Tien Chang, Veera Sekaran Nadarajan, Wee Joo Chng, Hein Than, Lay Cheng Lim, Yeow Tee Goh, Shenli Zhang, Dianne Poh, Patrick Tan, Ju‐Ee Seet, Mei‐Kim Ang, Noan‐Minh Chau, Quan‐Sing Ng, Daniel S.W. Tan, Manabu Soda, Kazutoshi Isobe, Markus M. Nöthen, Tien Yin Wong, Atif Shahab, Xiaoan Ruan, Valère Cacheux-Rataboul, Wing‐Kin Sung, Eng Huat Tan, Yasushi Yatabe, Hiroyuki Mano, Ross A. Soo, Tan Min Chin, Wan‐Teck Lim, Yijun Ruan, S. Tiong Ong - Nature Medicine 2012 被引用: 554