Holger Lerche

1989–2025 年に発表

159
論文数
21,370
被引用数
89
h 指数
154
i10 指数

被引用数

Holger Lerche の年別被引用数1993 年: 被引用 3 件1994 年: 被引用 4 件1995 年: 被引用 5 件1996 年: 被引用 13 件1997 年: 被引用 13 件1998 年: 被引用 2 件1999 年: 被引用 10 件2000 年: 被引用 17 件2001 年: 被引用 15 件2002 年: 被引用 31 件2003 年: 被引用 21 件2004 年: 被引用 61 件2005 年: 被引用 60 件2006 年: 被引用 58 件2007 年: 被引用 48 件2008 年: 被引用 87 件2009 年: 被引用 84 件2010 年: 被引用 119 件2011 年: 被引用 117 件2012 年: 被引用 127 件2013 年: 被引用 161 件2014 年: 被引用 176 件2015 年: 被引用 234 件2016 年: 被引用 195 件2017 年: 被引用 260 件2018 年: 被引用 191 件2019 年: 被引用 749 件2020 年: 被引用 845 件2021 年: 被引用 799 件2022 年: 被引用 588 件2023 年: 被引用 449 件2024 年: 被引用 790 件2025 年: 被引用 268 件2026 年: 被引用 2 件

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 1,940 件、この内訳の 20.2%ドイツ: 引用元論文 845 件、この内訳の 8.8%イギリス: 引用元論文 821 件、この内訳の 8.5%イタリア: 引用元論文 601 件、この内訳の 6.2%中国: 引用元論文 527 件、この内訳の 5.5%オーストラリア: 引用元論文 438 件、この内訳の 4.5%フランス: 引用元論文 432 件、この内訳の 4.5%カナダ: 引用元論文 410 件、この内訳の 4.3%オランダ: 引用元論文 344 件、この内訳の 3.6%ベルギー: 引用元論文 211 件、この内訳の 2.2%スイス: 引用元論文 209 件、この内訳の 2.2%スペイン: 引用元論文 204 件、この内訳の 2.1%
0%20.2%その他 27.4%

分野

  • Medicine41.7%
  • Biochemistry, Genetics and Molecular Biology35.9%
  • Neuroscience19.6%
  • Engineering0.7%
  • Psychology0.4%
  • Computer Science0.3%
  • その他1.4%

トピック

  • Epilepsy research and treatment12.4%
  • Neuroscience and Neuropharmacology Research8.3%
  • Ion channel regulation and function6.1%
  • Genomics and Rare Diseases5.3%
  • Genetics and Neurodevelopmental Disorders5.2%
  • Pharmacological Effects and Toxicity Studies2.9%
  • その他59.8%

共著者

全論文

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  1. Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Josef Zentner, Dieter Henrik Heiland, Horst Urbach, Bernhard J. Steinhoff, Thomas Bast, Laura Tassi, Giorgio Lo Russo, Çiğdem Özkara, Büğe Öz, Pavel Kršek, Silke Vogelgesang, Uwe Runge, Holger Lerche, Yvonne Weber, Mrinalini Honavar, José Pimentel, Alexis Arzimanoglou, Adriana Ulate-Campos, Soheyl Noachtar, Elisabeth Härtl, Olaf Schijns, Renzo Guerrini, Carmen Barba, Thomas S. Jacques, J. Helen Cross, Martha Feucht, Angelika Mühlebner, Thomas Grünwald, Eugen Trinka, Peter Winkler, António Gil‐Nagel, Rafael Toledano, Thomas Mayer, Martin Lutz, Basilios Zountsas, Kyriakos Garganis, Felix Rosenow, Anke Hermsen, Tim J. von Oertzen, Thomas L. Diepgen, G. Avanzini - New England Journal of Medicine 2017 被引用: 917

  2. Incidence and mechanisms of cardiorespiratory arrests in epilepsy monitoring units (MORTEMUS): a retrospective study

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , - The Lancet Neurology 2013 被引用: 1,121

  3. Genetic and phenotypic heterogeneity suggest therapeutic implications in SCN2A-related disorders

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Miriam Döcker, Thomas Bast, Tobias Loddenkemper, Lily C. Wong‐Kisiel, Friedrich Baumeister, Walid Fazeli, Pasquale Striano, Robertino Dilena, Elena Fontana, Federico Zara, Gerhard Kurlemann, Joerg Klepper, Jess G. Thoene, Daniel H. Arndt, Nicolas Deconinck, Thomas Schmitt‐Mechelke, Oliver Maier, Hiltrud Muhle, Beverly Wical, C. Finetti, Reinhard Brückner, Joachim Pietz, G. Golla, Dinesh Jillella, Karen Markussen Linnet, Perrine Charles, Ute Moog, Eve Õiglane‐Shlik, John F. Mantovani, Kristen Park, Marie Deprez, Damien Lederer, Sandrine Mary, Emmanuel Scalais, Laila Selim, Rudy Van Coster, Lieven Lagae, Marina Nikanorova, Helle Hjalgrim, Georg-Christoph Korenke, Marina Trivisano, Nicola Specchio, Berten Ceulemans, Thomas Dorn, Katherine L. Helbig, Katia Hardies, Hannah Stamberger, Peter De Jonghe, Sarah Weckhuysen, Johannes R. Lemke, Ingeborg Krägeloh‐Mann, Ingo Helbig, Gerhard Kluger, Holger Lerche, Rikke S. Møller - Brain 2017 被引用: 575

  4. Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Chantal Depondt, Orrin Devinsky, Dennis Dlugos, Colin P. Doherty, Christian E. Elger, Johan G. Eriksson, Thomas N. Ferraro, Martha Feucht, Ben Francis, André Franke, Jacqueline A. French, Saskia Freytag, Verena Gaus, Eric B. Geller, Christian Gieger, Tracy A. Glauser, Simon Glynn, David B. Goldstein, Hongsheng Gui, Youling Guo, Kevin F. Haas, Håkon Håkonarson, Kerstin Hallmann, Sheryl R. Haut, Erin L. Heinzen, Ingo Helbig, Christian Hengsbach, Helle Hjalgrim, Michele Iacomino, Andrés Ingason, Jennifer Jamnadas-Khoda, Michael R. Johnson, Reetta Kälviäinen, Anne-Mari Kantanen, Dalia Kasperavičiūtė, Dorothée Kasteleijn‐Nolst Trenité, Heidi E. Kirsch, Robert C. Knowlton, Bobby P.C. Koeleman, Roland Krause, Martin Krenn, Wolfram S. Kunz, Ruben Kuzniecky, Patrick Kwan, Dennis Lal, YL Lau, Anna‐Elina Lehesjoki, Holger Lerche, Costin Leu, Wolfgang Lieb, Dick Lindhout, Warren Lo, Íscia Lopes‐Cendes, Daniel H. Lowenstein, Alberto Malovini, Anthony G Marson, Thomas Mayer, Mark McCormack, James L. Mills, Nasir Mirza, Martina Moerzinger, Rikke S. Møller, Anne M. Molloy, Hiltrud Muhle, Mark R. Newton, Ping-Wing Ng, Markus M. Nöthen, Peter Nürnberg, Terence J. O’Brien, Karen Oliver ほか 58 名 - Nature Communications 2018 被引用: 513

  5. GAA-FGF14 ataxia (SCA27B): phenotypic profile, natural history progression and 4-aminopyridine treatment response

    著者: , , , , , , , , , , , , , , , , , , , , , , , , - Brain 2023 被引用: 114

  6. Transcutaneous Vagus Nerve Stimulation (tVNS) for Treatment of Drug-Resistant Epilepsy: A Randomized, Double-Blind Clinical Trial (cMPsE02)

    著者: , , , , , , , , , , , , , , , , - Brain stimulation 2016 被引用: 272

  7. Precision medicine for genetic epilepsy on the horizon: Recent advances, present challenges, and suggestions for continued progress

    著者: , , , , , , , , , , , , - Epilepsia 2022 被引用: 140

  8. Risk of Major Congenital Malformations and Exposure to Antiseizure Medication Monotherapy

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Maja Milovanović, Vladimír Šafčák, Meritxell Martínez Ferri, Torbjörn Tomson, Elisabeth Sellitto, Hsiang‐Yu Yu, Stephanie Hödl, Petr Marusič, Renata Listonova, Hana Krijtová, David Franc, Petr Bušek, Michaela Kajšová, Noémi Becser Andersen, Birthe Pedersen, Katarzyna Maria Mieszczanek, Katarzyna Cebula, Stefan Juhl, Birgitte Forsom Sondal, Karen Nielsen, Tatiana V. Danielsen, Elsebeth Bruun Christiansen, Jakob Christensen, Ovidio Solano Cabrera, Aleksei Rakitin, Anne Kirss, Anna Maija Saukkonen, Nino Gogatishvili, Dieter Dennig, Kerstin Erdmann, Christian M. Dippon, Bernhard J. Steinhoff, Lisa Langenbruch, Holger Lerche, Anja Herzer, Jan S. Gerdes, Elisa K. El-Allawy-Zielke, Hajo M. Hamer, Malgorzata Kalita, Martin Hirsch, Stephan Arnold, Hans‐Beatus Straub, Rebekka Lehmann, Christiane Asenbauer, Florian Losch, Wenke Grönheit, Matthias Lindenau, Ramshekhar N. Menon, Jafar Mehvari Habibabadi, Maria Paola Canevini, Elena Zambrelli, Katherine Turner, Michela Cecconi, A Paggi, Nicoletta Foschi, Antonio Gambardella, Simone Beretta, Angela Giglio, Gaia Fanella, Lorenzo Ferri, Francesca Bisulli, Alessandra Pistelli, Pietro Pignatta, Marta Maschio, Francesca Muzzi, Maria Sofia Cotelli, Etsuko Yamazaki, Kiyohito Terada, Yushi Inoue, Masahiro Mizobuchi ほか 56 名 - JAMA Neurology 2024 被引用: 113

  9. De Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Deb Pal, Aarno Palotie, Manuela Pendziwiat, Angela Robbiano, Filip Roelens, Felix Rosenow, Kaja Selmer, Jose M. Serratosa, Sanjay Sisodiya, Ulrich Stephani, Katalin Sterbova, Pasquale Striano, Arvid Suls, Tiina Talvik, Sarah von Spiczak, Yvonne Weber, Sarah Weckhuysen, Federico Zara, Bassel Abou-Khalil, Brian K. Alldredge, Eva Andermann, Frederick Andermann, Dina Amron, Jocelyn F. Bautista, Samuel F. Berkovic, Judith Bluvstein, Alex Boro, Gregory Cascino, Damian Consalvo, Patricia Crumrine, Orrin Devinsky, Dennis Dlugos, Michael P. Epstein, Miguel Fiol, Nathan B. Fountain, Jacqueline French, Daniel Friedman, Eric B. Geller, Tracy Glauser, Simon Glynn, Kevin Haas, Sheryl R. Haut, Jean Hayward, Sandra L. Helmers, Sucheta Joshi, Andres Kanner, Heidi E. Kirsch, Robert C. Knowlton, Eric H. Kossoff, Rachel Kuperman, Ruben Kuzniecky, Daniel H. Lowenstein, Shannon M. McGuire, Paul V. Motika, Edward J. Novotny, Ruth Ottman, Juliann M. Paolicchi, Jack Parent, Kristen Park, Annapurna Poduri, Lynette Sadleir, Ingrid E. Scheffer, Renée A. Shellhaas, Elliott Sherr, Jerry J. Shih, Rani Singh, Joseph Sirven, Michael C. Smith, Joe Sullivan, Liu Lin Thio ほか 31 名 - The American Journal of Human Genetics 2014 被引用: 454

  10. Current practice in diagnostic genetic testing of the epilepsies

    著者: , , , , , , , , , , , , , , , - Epileptic Disorders 2022 被引用: 102

  11. Clinical spectrum and genotype–phenotype associations of KCNA2-related encephalopathies

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Markus Wolff, Dragan Marjanović, Hande Çağlayan, Mutluay Arslan, Sérgio D.J. Pena, Sanjay M. Sisodiya, Simona Balestrini, Steffen Syrbe, Pierangelo Veggiotti, Johannes R. Lemke, Rikke S. Møller, Holger Lerche, Guido Rubboli - Brain 2017 被引用: 164

  12. A recurrent de novo mutation in KCNC1 causes progressive myoclonus epilepsy

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Danielle M. Andrade, Bernt A. Engelsen, Arielle Crespel, Matthias Lindenau, Ebba Lohmann, Veronica Saletti, João Massano, Michael Privitera, Alberto J. Espay, Birgit Kauffmann, Michael Duchowny, Rikke S. Møller, Rachel Straussberg, Zaid Afawi, Bruria Ben‐Zeev, Kaitlin E. Samocha, Mark J. Daly, Steven Petrou, Holger Lerche, Aarno Palotie, Anna-Elina Lehesjoki - Nature Genetics 2014 被引用: 315

  13. Phenotypic spectrum of GABRA1

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , José M. Serratosa, Pasquale Striano, Peter De Jonghe, Sarah Weckhuysen, Arvid Suls, Kai Muru, Inga Talvik, Tiina Talvik, Hiltrud Muhle, Ingo Borggraefe, Imma Rost, Renzo Guerrini, Holger Lerche, Johannes R. Lemke, Guido Rubboli, Snezana Maljevic - Neurology 2016 被引用: 141

  14. Neuronal mechanisms of mutations in SCN8A causing epilepsy or intellectual disability

    著者: , , , , , , , , , , , , , , , , , - Brain 2018 被引用: 132

  15. Spectrum of GABAA receptor variants in epilepsy

    著者: , , , , , , - Current Opinion in Neurology 2019 被引用: 87

  16. 4-Aminopyridine is a promising treatment option for patients with gain-of-function KCNA2 -encephalopathy

    著者: , , , , , , , , , , , , , , , , , , , , , , , , - Science Translational Medicine 2021 被引用: 83

  17. Randomized phase III study 306

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Inga Talvik, Stephan Arnold, A. Hufnagel, Frank Kerling, Holger Lerche, Soheyl Noachtar, Felix Rosenow, Joachim Springub, Bernhard J. Steinhoff, Konrad J. Werhahn, Raymond Tak Fai Cheung, Patrick Kwan, Ping Wing Ng, John S.D. Chan, Attila Balogh, István Kondákor, Magdolna Neuwirth, Péter Rajna, György Rásonyi, Joy Desai, Sudhir Kothari, Sita Sattaluri, Bhawna Sharma, Nandan Yardi, J. M. K. Murthy, Manmohan Mehndiratta, Kolichana Venkateshwaralu, Silvana Franceschetti, Guntis Karelis, Guntis Rozentals, Baiba Uskane, Rūta Mameniškienė, Irena Virketiene, Zariah Abdul Aziz, Kheng Seang Lim, Mei‐Ling Sharon Tai, Maria Epifania Collantes, Katerina Tanya P. Gosiengfiao, Anna Członkowska, Wiesław Drozdowski, Waldemar Fryze, Jacek Gawłowicz, Maria Mazurkiewicz‐Bełdzińska, E Motta, Carla Bentes, Luı́s Cunha, Georgine de Sousa, Jose Manuel Lopes Lima, Ioana Mı̂ndruță, Dezso Nagy, Sanda Maria Nica, E. D. Belousova, Kalinin Vv, Е. В. Левитина, Perunova Nb, Н. В. Пизова, И. Е. Повереннова, П. Н. Власов, Dragoslav Sokić, Ksenija Božić, N. Jović, Žarko Martinović, Mirjana Spasić, Seung Bong Hong, Joong Koo Kang, Sang Ho Kim, Sung Eun Kim, Byung-In Lee, Sang Kun Lee, Yong Won Cho ほか 25 名 - Neurology 2012 被引用: 429

  18. The phenotypic spectrum of SCN8A encephalopathy

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Andrea Bevot, Markus Wolff, Helle Hjalgrim, Renzo Guerrini, Ingrid E. Scheffer, Heather C. Mefford, Rikke S. Møller, Aarno Palotie, Anna-Elina Lehesjoki, Arvid Suls, Bobby P.C. Koeleman, Carla Marini, Christel Depienne, Dana Craiu, Deb K. Pal, Dorota Hoffman‐Zacharska, Eric Leguern, Federico Zara, Felix Rosenow, Hande Çağlayan, Helle Hjalgrim, Hiltrud Muhle, Holger Lerche, Ingo Helbig, Johanna Jähn, Johannes R. Lemke, José M. Serratosa, Kaja Kristine Selmer, Karl Martin Klein, Katalin Štěrbová, Nina Barišić, Padhraig Gormley, Pasquale Striano, Patrick May, Peter De Jonghe, Renzo Guerrini, Rikke S. Møller, Roland Krause, Rudi Balling, Sanjay M. Sisodiya, Sarah von Spiczak, Sarah Weckhuysen, Stéphanie Baulac, Tiina Talvik, Ulrich Stephani, Vladimı́r Komárek, Yvonne Weber - Neurology 2015 被引用: 285

  19. Gain-of-function variants in GABRD reveal a novel pathway for neurodevelopmental disorders and epilepsy

    著者: , , , , , , , , , , , , , , , , , , , , , - Brain 2021 被引用: 74

  20. Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Petia Dimova, Rosa Guerrero, José M. Serratosa, Tarja Linnankivi, Anna‐Elina Lehesjoki, Susanne Ruf, Markus Wolff, Sarah E. Buerki, Gabriele Wohlrab, Judith Kroell, Alexandre Datta, Barbara Fiedler, Gerhard Kurlemann, Gerhard Kluger, Andreas Hahn, D Edda Haberlandt, Christina Kutzer, Jürgen Sperner, Felicitas Becker, Yvonne Weber, Martha Feucht, Hannelore Steinböck, Birgit Neophythou, Gabriel M. Ronen, U Gruber‐Sedlmayr, Julia Geldner, Robert J Harvey, Per Hoffmann, Stefan Herms, Janine Altmüller, Mohammad R. Toliat, Hölger Thiele, Peter Nürnberg, Christian Wilhelm, Ulrich Stephani, Ingo Helbig, Holger Lerche, Fritz Zimprich, Bernd A. Neubauer, Saskia Biskup, Sarah von Spiczak - Nature Genetics 2013 被引用: 440

  21. Polygenic burden in focal and generalized epilepsies

    著者: , , , , , , , , , , , , , , , , , , , - Brain 2019 被引用: 151

  22. Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model

    著者: , , , , , , , , , , , , , , , , , , , - Journal of Clinical Investigation 2021 被引用: 64

  23. Genome-wide identification and phenotypic characterization of seizure-associated copy number variations in 741,075 individuals

    著者: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Dennis Lal, Namrata Gupta, Benjamin M. Neale, Samuel F. Berkovic, Holger Lerche, Daniel H. Lowenstein, Gianpiero L. Cavalleri, Patrick Cossette, Chris Cotsapas, Peter De Jonghe, Tracy Dixon‐Salazar, Renzo Guerrini, Håkon Håkonarson, Erin L. Heinzen, Ingo Helbig, Patrick Kwan, Anthony G Marson, Slavé Petrovski, Sitharthan Kamalakaran, Sanjay M. Sisodiya, Randy Stewart, Sarah Weckhuysen, Chantal Depondt, Dennis J. Dlugos, Ingrid E. Scheffer, Pasquale Striano, Catharine Freyer, Roland Krause, Patrick May, Kevin E. McKenna, Brigid M. Regan, Caitlin A. Bennett, Stephanie L. Leech, Costin Leu, David Lewis‐Smith, Authors from individual Epi25 cohorts:, Australia: Melbourne (AUSAUS), Australia: Royal Melbourne (AUSRMB), Terence J. O’Brien, Marian Todaro, Belgium: Antwerp (BELATW), Hannah Stamberger, Belgium: Brussels (BELULB), Chantal Depondti, Canada: Andrade (CANUTN), Danielle M. Andrade, Quratulain Zulfiqar Ali, Tara Sadoway, Switzerland: Bern (CHEUBB), Heinz Krestel, André Schaller, Cyprus (CYPCYP), Savvas Papacostas, Ioanna Kousiappa, George A. Tanteles, Christou Yiolanda, Czech Republic: Prague (CZEMTH), Katalin Štěrbová, Markéta Vlčková, Lucie Sedláčková, Petra Laššuthová, Germany: Frankfurt/Marburg (DEUPUM), Karl Martin Klein, Felix Rosenow, Philipp S. Reif, Susanne Knake, Germany: Giessen (DEUUGS), Bernd A. Neubauer, Friedrich Zimprich, Martha Feucht ほか 233 名 - Nature Communications 2023 被引用: 56

  24. Desynchronization of temporal lobe theta-band activity during effective anterior thalamus deep brain stimulation in epilepsy

    著者: , , , , , , , , , , , , - NeuroImage 2020 被引用: 46