James A. Spudich
1963–2025 年に発表
- 135
- 論文数
- 32,149
- 被引用数
- 94
- h 指数
- 132
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology55.2%
- Medicine30%
- Physics and Astronomy4.7%
- Neuroscience2.2%
- Engineering2.2%
- Materials Science1.4%
- その他4.3%
トピック
- Cardiomyopathy and Myosin Studies10.2%
- Cellular Mechanics and Interactions9.8%
- Microtubule and mitosis dynamics4.6%
- Muscle Physiology and Disorders4.2%
- Advanced Fluorescence Microscopy Techniques3.5%
- Force Microscopy Techniques and Applications3.5%
- その他64.2%
共著者
- Kathleen M. Ruppel34
- Darshan V. Trivedi8
- Leslie A. Leinwand8
- Hans M. Warrick7
- Ronald S. Rock7
- Saswata S. Sarkar7
- Arjun S. Adhikari6
- Neha Nandwani6
- Shirley Sutton6
- Stephen J. Kron6
- Suman Nag6
- Taro Q.P. Uyeda6
- Aminah Dawood5
- Arturo De Lozanne5
- Chao Liu5
- Daniel Bernstein5
- H. Lee Sweeney5
- Sivaraj Sivaramakrishnan5
- Amit Mehta4
- Anne Houdusse4
- Dan Song4
- Dietmar J. Manstein4
- Divya Pathak4
- Douglas N. Robinson4
全論文
- A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice
著者: Eric M. Green, Hiroko Wakimoto, Robert L. Anderson, Marc Evanchik, Joshua Gorham, Brooke C. Harrison, Marcus Henze, Raja Kawas, Johan D. Oslob, Héctor M. Rodrı́guez, Yonghong Song, William Wan, Leslie A. Leinwand, James A. Spudich, Robert S. McDowell, Jonathan G. Seidman, Christine E. Seidman - Science 2016 被引用: 722
- Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy
著者: Sara Ranjbarvaziri, Kristina B. Kooiker, Mathew Ellenberger, Giovanni Fajardo, Mingming Zhao, Alison Schroer Vander Roest, Rahel A. Woldeyes, Tiffany T. Koyano, Robyn Fong, Ning Ma, Lei Tian, Gavin M. Traber, Frandics Chan, John Perrino, Sushma Reddy, Wah Chiu, Joseph C. Wu, Joseph Y. Woo, Kathleen M. Ruppel, James A. Spudich, Michael P. Snyder, Kévin Contrepois, Daniel Bernstein - Circulation 2021 被引用: 295
- Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers
著者: Robert L. Anderson, Darshan V. Trivedi, Saswata S. Sarkar, Marcus Henze, Weikang Ma, Henry Gong, Christopher S. Rogers, Joshua Gorham, Fiona L. Wong, Makenna M. Morck, Jonathan G. Seidman, Kathleen M. Ruppel, Thomas C. Irving, Roger Cooke, Eric M. Green, James A. Spudich - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 被引用: 408
- A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division
著者: Uri Manor, Sadie R. Bartholomew, Gonen Golani, Eric T. Christenson, Michael M. Kozlov, Henry N. Higgs, James A. Spudich, Jennifer Lippincott‐Schwartz - eLife 2015 被引用: 349
- The Regulation of Rabbit Skeletal Muscle Contraction
著者: James A. Spudich, Susan Watt - Journal of Biological Chemistry 1971 被引用: 4,530
- Single myosin molecule mechanics: piconewton forces and nanometre steps
著者: Jeffrey T. Finer, Robert Simmons, James A. Spudich - Nature 1994 被引用: 1,954
- Three perspectives on the molecular basis of hypercontractility caused by hypertrophic cardiomyopathy mutations
著者: James A. Spudich - Pflügers Archiv - European Journal of Physiology 2019 被引用: 190
- Optimized localization analysis for single-molecule tracking and super-resolution microscopy
著者: Kim I. Mortensen, L. Stirling Churchman, James A. Spudich, Henrik Flyvbjerg - Nature Methods 2010 被引用: 892
- The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations
著者: Suman Nag, Darshan V. Trivedi, Saswata S. Sarkar, Arjun S. Adhikari, Margaret S. Sunitha, Shirley Sutton, Kathleen M. Ruppel, James A. Spudich - Nature Structural & Molecular Biology 2017 被引用: 233
- Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients
著者: Suman Nag, Sampath K. Gollapudi, Carlos del Río, James A. Spudich, Robert McDowell - Science Advances 2023 被引用: 75
- Cryo-EM structure of the folded-back state of human β-cardiac myosin
著者: Alessandro Grinzato, Daniel Auguin, Carlos Kikuti, Neha Nandwani, Dihia Moussaoui, Divya Pathak, Eaazhisai Kandiah, Kathleen M. Ruppel, James A. Spudich, Anne Houdusse, Julien Robert‐Paganin - Nature Communications 2023 被引用: 70
- Hypertrophic cardiomyopathy: Mutations to mechanisms to therapies
著者: Masataka Kawana, James A. Spudich, Kathleen M. Ruppel - Frontiers in Physiology 2022 被引用: 56
- The myosin swinging cross-bridge model
著者: James A. Spudich - Nature Reviews Molecular Cell Biology 2001 被引用: 335
- SETD3 is an actin histidine methyltransferase that prevents primary dystocia
著者: Alex W. Wilkinson, Jonathan Diep, Shaobo Dai, Shuo Liu, Yaw Shin Ooi, Dan Song, Tie‐Mei Li, J.R. Horton, Xing Zhang, Chao Liu, Darshan V. Trivedi, Katherine M. Ruppel, José G. Vilches-Moure, Kerriann M. Casey, Justin Mak, Tina M. Cowan, Joshua E. Elias, Claude M. Nagamine, James A. Spudich, Xiaodong Cheng, Jan E. Carette, Or Gozani - Nature 2018 被引用: 172
- Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state
著者: Alison Schroer Vander Roest, Chao Liu, Makenna M. Morck, Kristina B. Kooiker, Gwanghyun Jung, Dan Song, Aminah Dawood, Arnav Jhingran, Gaspard Pardon, Sara Ranjbarvaziri, Giovanni Fajardo, Mingming Zhao, Kenneth S. Campbell, Beth L. Pruitt, James A. Spudich, Kathleen M. Ruppel, Daniel Bernstein - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 被引用: 82
- The myosin superfamily at a glance
著者: M. Amanda Hartman, James A. Spudich - Journal of Cell Science 2012 被引用: 328
- The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin
著者: Saswata S. Sarkar, Darshan V. Trivedi, Makenna M. Morck, Arjun S. Adhikari, Shaik Pasha, Kathleen M. Ruppel, James A. Spudich - Science Advances 2020 被引用: 100
- Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function
著者: Ruth F. Sommese, Jongmin Sung, Suman Nag, Shirley Sutton, John C. Deacon, Elizabeth Choe, Leslie A. Leinwand, Kathleen M. Ruppel, James A. Spudich - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 被引用: 181
- Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light
著者: Darshan V. Trivedi, Arjun S. Adhikari, Saswata S. Sarkar, Kathleen M. Ruppel, James A. Spudich - Biophysical Reviews 2017 被引用: 161
- The myosin mesa and a possible unifying hypothesis for the molecular basis of human hypertrophic cardiomyopathy
著者: James A. Spudich - Biochemical Society Transactions 2015 被引用: 151
- Myosin-V is a processive actin-based motor
著者: Amit Mehta, Ronald S. Rock, Matthias Rief, James A. Spudich, Mark S. Mooseker, Richard E. Cheney - Nature 1999 被引用: 800
- β-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity
著者: Arjun S. Adhikari, Darshan V. Trivedi, Saswata S. Sarkar, Dan Song, Kristina B. Kooiker, Daniel Bernstein, James A. Spudich, Kathleen M. Ruppel - Nature Communications 2019 被引用: 90
- Myosin step size
著者: Taro Q.P. Uyeda, Stephen J. Kron, James A. Spudich - Journal of Molecular Biology 1990 被引用: 461
- Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation
著者: Julian R. Homburger, Eric M. Green, Colleen Caleshu, Margaret S. Sunitha, R. E. Taylor, Kathleen M. Ruppel, Raghu Metpally, Steven D. Colan, Michelle Michels, Sharlene M. Day, Iacopo Olivotto, Carlos D. Bustamante, Frederick E. Dewey, Carolyn Y. Ho, James A. Spudich, Euan A. Ashley - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 130
