James A. Wells
1953–2025 年に発表
- 187
- 論文数
- 42,884
- 被引用数
- 110
- h 指数
- 185
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology46.6%
- Medicine30.8%
- Computer Science4.7%
- Chemistry4.1%
- Immunology and Microbiology3.2%
- Neuroscience2.7%
- その他7.9%
トピック
- Monoclonal and Polyclonal Antibodies Research4.3%
- Protein Structure and Dynamics3.8%
- Computational Drug Discovery Methods3.3%
- Chemical Synthesis and Analysis2.4%
- Ubiquitin and proteasome pathways2.4%
- Click Chemistry and Applications2.1%
- その他81.7%
共著者
- Brian C. Cunningham22
- Kevin Leung20
- Irene Lui13
- James R. Byrnes11
- Germaine Fuh10
- Shion A. Lim10
- Susanna K. Elledge9
- T.J. Rettenmaier8
- Xin Zhou8
- Abraham M. de Vos7
- Amy M. Weeks7
- Kaitlin Schaefer7
- Lisa L. Kirkemo7
- Andrej Šali6
- Jeff E. Glasgow6
- Jie Zhou6
- Olivier Julien6
- Sami Mahrus6
- Alexander J. Martinko5
- Andrew C. Braisted5
- Arun P. Wiita5
- Charles Y. Chiu5
- David A. Estell5
- Henry B. Lowman5
全論文
- K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
著者: J.M. Ostrem, Ulf Peters, Martin L. Sos, James A. Wells, Kevan M. Shokat - Nature 2013 被引用: 2,555
- Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
著者: Adam D. Cotton, Duy Nguyen, Josef A. Gramespacher, Ian B. Seiple, James A. Wells - Journal of the American Chemical Society 2021 被引用: 507
- Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins
著者: Katarina Pance, Josef A. Gramespacher, James R. Byrnes, Fernando Salangsang, Juan A. Cámara, Adam D. Cotton, Veronica Steri, James A. Wells - Nature Biotechnology 2022 被引用: 250
- Caspases and their substrates
著者: Olivier Julien, James A. Wells - Cell Death and Differentiation 2017 被引用: 811
- Extracellular targeted protein degradation: an emerging modality for drug discovery
著者: James A. Wells, Kaan Kumru - Nature Reviews Drug Discovery 2023 被引用: 160
- Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
著者: Alban Ordureau, Shireen A. Sarraf, David M. Duda, Jin‐Mi Heo, Mark P. Jedrychowski, Vladislav O. Sviderskiy, Jennifer L. Olszewski, James T. Koerber, Tiao Xie, Sean A. Beausoleil, James A. Wells, Steven P. Gygi, Brenda A. Schulman, J. Wade Harper - Molecular Cell 2014 被引用: 715
- Sexually Dimorphic Neurons in the Ventromedial Hypothalamus Govern Mating in Both Sexes and Aggression in Males
著者: Cindy F. Yang, Michael C. Chiang, Daniel C. Gray, Mahalakshmi Prabhakaran, Maricruz Alvarado, Scott A. Juntti, Elizabeth K. Unger, James A. Wells, Nirao M. Shah - Cell 2013 被引用: 740
- Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality
著者: Michelle R. Arkin, Yinyan Tang, James A. Wells - Chemistry & Biology 2014 被引用: 1,055
- Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
著者: James A. Wells, Christopher L. McClendon - Nature 2007 被引用: 1,972
- Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability
著者: Zhipeng Li, Lucas Ferguson, Kirandeep K. Deol, Melissa A. Roberts, Leslie Magtanong, Joseph M. Hendricks, Gergey Alzaem Mousa, Seda Kilinc, Kaitlin Schaefer, James A. Wells, Michael C. Bassik, Andrei Goga, Scott J. Dixon, Nicholas T. Ingolia, James A. Olzmann - Nature Chemical Biology 2022 被引用: 132
- Redox-based reagents for chemoselective methionine bioconjugation
著者: Shixian Lin, Xiaoyu Yang, Shang Jia, Amy M. Weeks, Michael Hornsby, Peter S. Lee, R.V. Nichiporuk, Anthony T. Iavarone, James A. Wells, F. Dean Toste, Christopher J. Chang - Science 2017 被引用: 531
- CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites
著者: Peter Cimermančič, Patrick Weinkam, T.J. Rettenmaier, Leon Bichmann, D.A. Keedy, R.A. Woldeyes, Dina Schneidman‐Duhovny, Omar Demerdash, Julie C. Mitchell, James A. Wells, James S. Fraser, Andrej Săli - Journal of Molecular Biology 2016 被引用: 286
- An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering
著者: D.A. Keedy, Z.B. Hill, J.T. Biel, Emily L. Kang, T.J. Rettenmaier, J. Brandão-Neto, Nicholas M. Pearce, F. von Delft, James A. Wells, James S. Fraser - eLife 2018 被引用: 207
- The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28
著者: Yannick D. Müller, Duy Nguyen, Leonardo M. R. Ferreira, Patrick Ho, Caroline Raffin, Roxxana Valeria Beltran Valencia, Zion Congrave‐Wilson, Theodore L. Roth, Justin Eyquem, Frédéric Van Gool, Alexander Marson, Laurent Perez, James A. Wells, Jeffrey A. Bluestone, Qizhi Tang - Frontiers in Immunology 2021 被引用: 132
- Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells
著者: Zhi Lin, Kaitlin Schaefer, Irene Lui, Zi Yao, Andrea Fossati, Danielle L. Swaney, Aji Palar, Andrej Šali, James A. Wells - Science 2024 被引用: 121
- Roadmap for Optimizing and Broadening Antibody-Based PROTACs for Degradation of Cell Surface Proteins
著者: Josef A. Gramespacher, Adam D. Cotton, Paul W. W. Burroughs, Ian B. Seiple, James A. Wells - ACS Chemical Biology 2022 被引用: 94
- Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
著者: Michelle R. Arkin, James A. Wells - Nature Reviews Drug Discovery 2004 被引用: 1,685
- The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance
著者: Ian Ferguson, Bonell Patiño-Escobar, Sami T. Tuomivaara, Yu-Hsiu T. Lin, Matthew A. Nix, Kevin Leung, Corynn Kasap, Emilio Ramos, Wilson Nieves Vasquez, Alexis Talbot, Martina Hale, Akul Naik, Audrey Kishishita, Priya Choudhry, Antonia Lopez‐Girona, Weili Miao, Sandy W. Wong, Jeffrey L. Wolf, Thomas Martin, Nina Shah, Scott Vandenberg, Sonam Prakash, Lenka Bešše, Christoph Driessen, Avery D. Posey, R. Dyche Mullins, Justin Eyquem, James A. Wells, Arun P. Wiita - Nature Communications 2022 被引用: 130
- A Hot Spot of Binding Energy in a Hormone-Receptor Interface
著者: Tim Clackson, James A. Wells - Science 1995 被引用: 2,010
- Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance
著者: Yannick D. Müller, Leonardo M. R. Ferreira, Émilie Ronin, Patrick Ho, Vinh Nguyen, Gaetano Faleo, Yu Zhou, Karim Lee, Kevin Leung, Nikolaos Skartsis, Anupurna M. Kaul, Arend Mulder, Frans H.J. Claas, James A. Wells, Jeffrey A. Bluestone, Qizhi Tang - Frontiers in Immunology 2021 被引用: 98
- Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein
著者: Wei Wang, Linh Hồ Thùy Nguyễn, Christopher Burlak, Fariba Chegini, Feng Guo, Tim Chataway, Shulin Ju, Oriana S. Fisher, David W. Miller, Debajyoti Datta, Fang Wu, Chun-Xiang Wu, Anuradha Landeru, James A. Wells, Mark Cookson, Matthew B. Boxer, Craig J. Thomas, Wei Gai, Dagmar Ringe, Gregory A. Petsko, Quyen Q. Hoang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 266
- Site-directed ligand discovery
著者: Daniel A. Erlanson, Andrew C. Braisted, D.R. Raphael, Mike Randal, Robert M. Stroud, Eric M. Gordon, James A. Wells - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 被引用: 466
- Searching for new allosteric sites in enzymes
著者: Jeanne A. Hardy, James A. Wells - Current Opinion in Structural Biology 2004 被引用: 337
- Stable heterodimers from remodeling the domain interface of a homodimer using a phage display library
著者: S. Atwell, John Brady Ridgway, James A. Wells, Paul Carter - Journal of Molecular Biology 1997 被引用: 266
