Jeffrey S. Chamberlain
1977–2025 年に発表
- 119
- 論文数
- 20,613
- 被引用数
- 86
- h 指数
- 115
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology76.7%
- Medicine16.8%
- Neuroscience2.3%
- Immunology and Microbiology1.2%
- Agricultural and Biological Sciences0.9%
- Engineering0.9%
- その他1.2%
トピック
- Muscle Physiology and Disorders16.3%
- Virus-based gene therapy research7%
- CRISPR and Genetic Engineering6.3%
- Cardiomyopathy and Myosin Studies3.5%
- RNA Interference and Gene Delivery3.2%
- Adipose Tissue and Metabolism3.2%
- その他60.5%
共著者
- Paul Gregorevic14
- James M. Allen13
- Stephen D. Hauschka13
- Dongsheng Duan10
- John A. Faulkner10
- Kevin P. Campbell10
- Guy L. Odom9
- Jill A. Rafael9
- C. Thomas Caskey8
- Michael J. Blankinship8
- Yongping Yue7
- Niclas E. Bengtsson6
- Joel R. Chamberlain5
- John K. Hall5
- Neil M. Cole5
- Robert W. Crawford5
- Scott Q. Harper5
- Stephanie F. Phelps5
- Andrea Amalfitano4
- Christiana DelloRusso4
- Christine L. Halbert4
- Dennis J. Hartigan-O’Connor4
- Eric Finn4
- Glen B. Banks4
全論文
- High levels of AAV vector integration into CRISPR-induced DNA breaks
著者: Killian S. Hanlon, Benjamin P. Kleinstiver, Sara P. Garcia, Mikołaj Piotr Zaborowski, Adrienn Volak, Stefan E. Spirig, Alissa Muller, Alexander A. Sousa, Shengdar Q. Tsai, Niclas E. Bengtsson, Camilla Lööv, Martin Ingelsson, Jeffrey S. Chamberlain, David P. Corey, Martin J. Aryee, J. Keith Joung, Xandra O. Breakefield, Casey A. Maguire, Bence György - Nature Communications 2019 被引用: 432
- Cas9 immunity creates challenges for CRISPR gene editing therapies
著者: Julie M. Crudele, Jeffrey S. Chamberlain - Nature Communications 2018 被引用: 251
- Design of Tissue-specific Regulatory Cassettes for High-level rAAV-mediated Expression in Skeletal and Cardiac Muscle
著者: Maja Z. Salva, Charis L. Himeda, Phillip W.L. Tai, Eiko Nishiuchi, Paul Gregorevic, James M. Allen, Eric Finn, Quynh G Nguyen, Michael J. Blankinship, Leonard Meuse, Jeffrey S. Chamberlain, Stephen D. Hauschka - Molecular Therapy 2007 被引用: 226
- Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy
著者: Niclas E. Bengtsson, John K. Hall, Guy L. Odom, Michael Phelps, Colin Andrus, R. David Hawkins, Stephen D. Hauschka, Joel R. Chamberlain, Jeffrey S. Chamberlain, Jeffrey S. Chamberlain, Jeffrey S. Chamberlain - Nature Communications 2017 被引用: 384
- Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin
著者: Catherine E. Winbanks, Kate L. Weeks, Rachel E. Thomson, Patricio V. Sepulveda, Claudia Beyer, Hongwei Qian, Justin L. Chen, James M. Allen, Graeme I. Lancaster, Mark A. Febbraio, Craig A. Harrison, Julie R. McMullen, Jeffrey S. Chamberlain, Paul Gregorevic - The Journal of Cell Biology 2012 被引用: 214
- Split intein-mediated protein trans-splicing to express large dystrophins
著者: Hichem Tasfaout, Christine L. Halbert, Timothy S. McMillen, James M. Allen, Theodore R. Reyes, Galina Flint, Dirk Grimm, Stephen D. Hauschka, Michael Regnier, Jeffrey S. Chamberlain - Nature 2024 被引用: 59
- Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy
著者: Sharla M. Birch, Michael W. Lawlor, Thomas J. Conlon, Lee‐Jae Guo, Julie M. Crudele, Eleanor C. Hawkins, Peter P. Nghiem, Mihye Ahn, Hui Meng, Margaret Beatka, Brittany A. Fickau, Juan Carlos Prieto, Martin Styner, Michael J. Struharik, Courtney Shanks, Kristy J. Brown, Diane Golebiowski, Amanda K. Bettis, Cynthia Balog-Alvarez, Nathalie Clément, Kirsten E. Coleman, Manuela Corti, Xiufang Pan, Stephen D. Hauschka, J. Patrick Gonzalez, Carl Morris, Joel Schneider, Dongsheng Duan, Jeffrey S. Chamberlain, Barry J. Byrne, Joe N. Kornegay - Science Translational Medicine 2023 被引用: 68
- Modular flexibility of dystrophin: Implications for gene therapy of Duchenne muscular dystrophy
著者: Scott Q. Harper, Michael A. Hauser, Christiana DelloRusso, Dongsheng Duan, Robert W. Crawford, Stephanie F. Phelps, Hollie A. Harper, Ann S. Robinson, John F. Engelhardt, Susan V. Brooks, Jeffrey S. Chamberlain - Nature Medicine 2002 被引用: 561
- Systemic delivery of genes to striated muscles using adeno-associated viral vectors
著者: Paul Gregorevic, Michael J. Blankinship, James M. Allen, Robert W. Crawford, Leonard Meuse, Daniel G. Miller, David W. Russell, Jeffrey S. Chamberlain - Nature Medicine 2004 被引用: 611
- Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery
著者: Sajedah M. Hindi, Michael J. Petrany, Elena Greenfeld, Leah C. Focke, A. Cramer, Michael A. Whitt, Ramzi J. Khairallah, Christopher W. Ward, Jeffrey S. Chamberlain, Vikram Prasad, Benjamin Podbilewicz, Douglas P. Millay - Cell 2023 被引用: 34
- AAV-based gene therapies for the muscular dystrophies
著者: Julie M. Crudele, Jeffrey S. Chamberlain - Human Molecular Genetics 2019 被引用: 118
- Development of Novel Micro-dystrophins with Enhanced Functionality
著者: Julian N. Ramos, Katrin Hollinger, Niclas E. Bengtsson, J. M. Allen, Stephen D. Hauschka, Jeffrey S. Chamberlain - Molecular Therapy 2019 被引用: 114
- Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy
著者: Yi Lai, Gail D. Thomas, Yongping Yue, H. T. Yang, Dejia Li, Chun Long, Luke M. Judge, Brian Bostick, Jeffrey S. Chamberlain, Ronald L. Terjung, Dongsheng Duan - Journal of Clinical Investigation 2009 被引用: 380
- Progress toward Gene Therapy for Duchenne Muscular Dystrophy
著者: Joel R. Chamberlain, Joel R. Chamberlain, Jeffrey S. Chamberlain, Jeffrey S. Chamberlain - Molecular Therapy 2017 被引用: 222
- Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors
著者: Yi Lai, Yongping Yue, Mingju Liu, Arkasubhra Ghosh, John F. Engelhardt, Jeffrey S. Chamberlain, Dongsheng Duan - Nature Biotechnology 2005 被引用: 216
- Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification
著者: Jeffrey S. Chamberlain, Richard A. Gibbs, Joel E. Rainer, Phi Nga Nguyen, Christopher D. Thomas - Nucleic Acids Research 1988 被引用: 1,268
- Dystrophin‐deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma
著者: Jeffrey S. Chamberlain, Joseph M. Metzger, Morayma Reyes, DeWayne Townsend, John A. Faulkner - The FASEB Journal 2007 被引用: 322
- Skeletal Muscle Contractions Induce Acute Changes in Cytosolic Superoxide, but Slower Responses in Mitochondrial Superoxide and Cellular Hydrogen Peroxide
著者: Tim Pearson, Tabitha Kabayo, Rainer Ng, Jeffrey S. Chamberlain, Anne McArdle, Malcolm J. Jackson - PLoS ONE 2014 被引用: 106
- Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells
著者: Arianna Dellavalle, Maurilio Sampaolesi, Rossana Tonlorenzi, Enrico Tagliafico, Benedetto Sacchetti, Laura Perani, A Innocenzi, Beatriz G. Gálvez, Graziella Messina, Roberta Morosetti, Sheng Li, M. Belicchi, Giuseppe M. Peretti, Jeffrey S. Chamberlain, Woodring E. Wright, Yvan Torrente, Stefano Ferrari, Paolo Bianco, Giulio Cossu - Nature Cell Biology 2007 被引用: 974
- Recombinant Adeno-associated Virus Transduction and Integration
著者: Brian Schultz, Jeffrey S. Chamberlain - Molecular Therapy 2008 被引用: 208
- PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing
著者: Domagoj Cikes, Kareem Elsayad, Erdinç Sezgin, Erika Koitai, Ferenc Torma, Michael Orthofer, Rebecca Yarwood, Leonhard X. Heinz, Vitaly Sedlyarov, N. Darwish, Adrian Taylor, Sophie Grapentine, Fathiya Al-Murshedi, Anne Abot, Adelheid Weidinger, Candice Kutchukian, Colline Sanchez, Shane J. F. Cronin, Maria Novatchkova, Anoop Kavirayani, Thomas Schuetz, Bernhard J. Haubner, Lisa Haas, Astrid Hagelkrüys, Suzanne Jackowski, Andrey V. Kozlov, Vincent Jacquemond, Claude Knauf, Giulio Superti‐Furga, Eric Rullman, Thomas Gustafsson, John McDermot, Martin Lowe, Zsolt Radák, Jeffrey S. Chamberlain, Marica Bakovic, Siddharth Banka, Josef Penninger - Nature Metabolism 2023 被引用: 57
- Microdystrophin Expression as a Surrogate Endpoint for Duchenne Muscular Dystrophy Clinical Trials
著者: Jeffrey S. Chamberlain, Melissa A. Robb, Serge Braun, Kristy J. Brown, Olivier Danos, Annie Ganot, Pedro Gonzalez‐Alegre, Nina Hunter, Craig M. McDonald, Carl Morris, Mark Tobolowsky, Kathryn R. Wagner, Olivia Ziolkowski, Dongsheng Duan - Human Gene Therapy 2023 被引用: 33
- Innate and adaptive AAV-mediated immune responses in a mouse model of Duchenne muscular dystrophy
著者: Michael R. Emami, Alejandro Espinoza, Courtney S. Young, Feiyang Ma, Philip K. Farahat, Philip L. Felgner, Jeffrey S. Chamberlain, Xiangmin Xu, April D. Pyle, Matteo Pellegrini, S. Armando Villalta, Melissa J. Spencer - Molecular Therapy — Methods & Clinical Development 2023 被引用: 21
- Characterization of Dystrophin in Muscle-Biopsy Specimens from Patients with Duchenne's or Becker's Muscular Dystrophy
著者: Eric P. Hoffman, Kenneth H. Fischbeck, Robert H. Brown, Margaret A. Johnson, Rosella Medori, John D. Loire, John B. Harris, R Waterston, Michael H. Brooke, Linda A. Specht, William J. Kupsky, Jeffrey S. Chamberlain, C. Thomas Caskey, Frederic Shapiro, Louis M. Kunkel - New England Journal of Medicine 1988 被引用: 927
