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Jochen Utikal

2001–2025 年に発表

200
論文数
40,590
被引用数
85
h 指数
191
i10 指数

被引用数

Jochen Utikal の年別被引用数1974 年: 被引用 1 件1987 年: 被引用 1 件1991 年: 被引用 3 件1992 年: 被引用 3 件2001 年: 被引用 1 件2002 年: 被引用 3 件2003 年: 被引用 4 件2004 年: 被引用 2 件2005 年: 被引用 6 件2006 年: 被引用 15 件2007 年: 被引用 36 件2008 年: 被引用 109 件2009 年: 被引用 238 件2010 年: 被引用 218 件2011 年: 被引用 173 件2012 年: 被引用 172 件2013 年: 被引用 242 件2014 年: 被引用 244 件2015 年: 被引用 268 件2016 年: 被引用 386 件2017 年: 被引用 497 件2018 年: 被引用 623 件2019 年: 被引用 1,744 件2020 年: 被引用 2,199 件2021 年: 被引用 2,414 件2022 年: 被引用 2,015 件2023 年: 被引用 1,689 件2024 年: 被引用 2,566 件2025 年: 被引用 1,294 件2026 年: 被引用 83 件1975〜1986 年は被引用が無いため表示していません1988〜1990 年は被引用が無いため表示していません1993〜2000 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 5,138 件、この内訳の 24.2%中国: 引用元論文 3,020 件、この内訳の 14.3%ドイツ: 引用元論文 1,503 件、この内訳の 7.1%イタリア: 引用元論文 994 件、この内訳の 4.7%イギリス: 引用元論文 989 件、この内訳の 4.7%フランス: 引用元論文 734 件、この内訳の 3.5%オーストラリア: 引用元論文 660 件、この内訳の 3.1%スペイン: 引用元論文 601 件、この内訳の 2.8%オランダ: 引用元論文 588 件、この内訳の 2.8%カナダ: 引用元論文 534 件、この内訳の 2.5%日本: 引用元論文 528 件、この内訳の 2.5%インド: 引用元論文 507 件、この内訳の 2.4%
0%24.2%その他 25.4%

機関

分野

  • Medicine47.7%
  • Biochemistry, Genetics and Molecular Biology30.3%
  • Immunology and Microbiology14.4%
  • Computer Science3.5%
  • Engineering1.4%
  • Neuroscience0.8%
  • その他1.9%

トピック

  • Cancer Immunotherapy and Biomarkers9.3%
  • Immunotherapy and Immune Responses6.4%
  • Cutaneous Melanoma Detection and Management4.6%
  • Melanoma and MAPK Pathways3.7%
  • Immune cells in cancer3.6%
  • CAR-T cell therapy research3.6%
  • その他68.8%

共著者

全論文

検索で開く
  1. Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

    著者: Uğur Şahin, Evelyna Derhovanessian, Matthias Miller, Björn‐Philipp Kloke, Petra Simon, Martin Löwer, Valesca Bukur, Arbel D. Tadmor, Ulrich Luxemburger, Barbara Schrörs, Tana Omokoko, Mathias Vormehr, Christian Albrecht, Anna Paruzynski, Andreas N. Kuhn, Janina Buck, Sandra Heesch, Katharina Schreeb, Felicitas Müller, Inga Ortseifer, Isabel Vogler, Eva Godehardt, Sebastian Attig, Richard Rae, Andrea Breitkreuz, Claudia Tolliver, M Suchan, Goran Martic, Alexander Hohberger, Patrick Sorn, Jan Diekmann, Janko Ciesla, Olga Waksmann, Alexandra-Kemmer Brück, Meike Witt, Martina Zillgen, Andrée Rothermel, Barbara Kasemann, David Langer, Stefanie Bolte, Mustafa Diken, Sebastian Kreiter, Romina Nemecek, Christoffer Gebhardt, Stephan Grabbe, Christoph Höller, Jochen Utikal, Christoph Huber, Carmen Loquai, Özlem Türeci - Nature 2017 被引用: 2,501

  2. An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

    著者: Uğur Şahin, Petra Oehm, Evelyna Derhovanessian, Robert A. Jabulowsky, Mathias Vormehr, Maike Gold, Daniel Maurus, Doreen Schwarck-Kokarakis, Andreas N. Kuhn, Tana Omokoko, Lena M. Kranz, Mustafa Diken, Sebastian Kreiter, Heinrich Haas, Sebastian Attig, Richard Rae, Katarina Ćuk, Alexandra Kemmer-Brück, Andrea Breitkreuz, Claudia Tolliver, Janina Caspar, Juliane Quinkhardt, Lisa Hebich, Malte Stein, Alexander Hohberger, Isabel Vogler, Inga Liebig, Stephanie Renken, Julian Sikorski, Melanie Leierer, Verena Müller, Heidrun Mitzel-Rink, Matthias Miederer, Christoph Huber, Stephan Grabbe, Jochen Utikal, Andreas Pinter, Roland Kaufmann, Jessica C. Hassel, Carmen Loquai, Özlem Türeci - Nature 2020 被引用: 1,043

  3. Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

    著者: Eliezer M. Van Allen, Diana Miao, Bastian Schilling, Sachet A. Shukla, Christian U. Blank, Lisa Zimmer, Antje Sucker, Uwe Hillen, Marnix H. Geukes Foppen, Simone M. Goldinger, Jochen Utikal, Jessica C. Hassel, Benjamin Weide, Katharina C. Kaehler, Carmen Loquai, Peter Mohr, Ralf Gutzmer, Reinhard Dummer, Stacey Gabriel, Catherine J. Wu, Dirk Schadendorf, Levi A. Garraway - Science 2015 被引用: 2,995

  4. Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

    著者: David Liu, Bastian Schilling, Derek Liu, Antje Sucker, Elisabeth Livingstone, Livnat Jerby‐Arnon, Lisa Zimmer, Ralf Gutzmer, Imke Satzger, Carmen Loquai, Stephan Grabbe, Natalie I. Vokes, Claire A. Margolis, Jake R. Conway, Meng Xiao He, Haitham Elmarakeby, Felix Dietlein, Diana Miao, Adam Tracy, Helen Gogas, Simone M. Goldinger, Jochen Utikal, Christian U. Blank, Ricarda Rauschenberg, Dagmar von Bubnoff, Angela M. Krackhardt, Benjamin Weide, Sebastian Haferkamp, Felix Kiecker, Ben Izar, Levi A. Garraway, Aviv Regev, Keith T. Flaherty, Annette Paschen, Eliezer M. Van Allen, Dirk Schadendorf - Nature Medicine 2019 被引用: 1,105

  5. Myeloid-derived suppressor cells in cancer and cancer therapy

    著者: Samantha Lasser, Feyza Gül Özbay Kurt, Ihor Arkhypov, Jochen Utikal, Viktor Umansky - Nature Reviews Clinical Oncology 2024 被引用: 416

  6. Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression

    著者: Christopher Groth, Xiaoying Hu, Rebekka Weber, Viktor Fleming, Peter Altevogt, Jochen Utikal, Viktor Umansky - British Journal of Cancer 2018 被引用: 817

  7. Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma

    著者: Georgina V. Long, Daniil Stroyakovskiy, Helen Gogas, E. Levchenko, Filippo de Braud, James Larkin, Claus Garbe, Thomas Jouary, Axel Hauschild, Jean‐Jacques Grob, Vanna Chiarion‐Sileni, Célèste Lebbé, Mario Mandalà, Michael Millward, Ana Arance, Igor Bondarenko, John B.A.G. Haanen, Johan Hansson, Jochen Utikal, Virginia Ferraresi, Н. В. Коваленко, Peter Mohr, Volodymyr Probachai, Dirk Schadendorf, Paul Nathan, Caroline Robert, Antoni Ribas, Douglas J. DeMarini, Jhangir G Irani, Michelle Casey, Danièle Ouellet, Anne‐Marie Martin, Ngocdiep T. Le, Kiran Patel, Keith T. Flaherty - New England Journal of Medicine 2014 被引用: 1,871

  8. IL-6 as a major regulator of MDSC activity and possible target for cancer immunotherapy

    著者: Rebekka Weber, Christopher Groth, Samantha Lasser, Ihor Arkhypov, Vera Petrova, Peter Altevogt, Jochen Utikal, Viktor Umansky - Cellular Immunology 2020 被引用: 312

  9. Explainable artificial intelligence in skin cancer recognition: A systematic review

    著者: Katja Hauser, Alexander Kurz, Sarah Haggenmüller, Roman C. Maron, Christof von Kalle, Jochen Utikal, Friedegund Meier, Sarah Hobelsberger, Frank Friedrich Gellrich, Mildred Sergon, Axel Hauschild, Lars E. French, Lucie Heinzerling, Justin Gabriel Schlager, Kamran Ghoreschi, Max Schlaak, Franz J. Hilke, Gabriela Poch, Heinz Kutzner, Carola Berking, Markus V. Heppt, Michael Erdmann, Sebastian Haferkamp, Dirk Schadendorf, Wiebke Sondermann, Matthias Goebeler, Bastian Schilling, Jakob Nikolas Kather, Stefan Fröhling, Daniel B. Lipka, Achim Hekler, Eva Krieghoff‐Henning, Titus J. Brinker - European Journal of Cancer 2022 被引用: 161

  10. Dermatologist-like explainable AI enhances trust and confidence in diagnosing melanoma

    著者: Tirtha Chanda, Katja Hauser, Sarah Hobelsberger, Tabea-Clara Bucher, Carina Nogueira Garcia, Christoph Wies, Harald Kittler, Philipp Tschandl, Cristián Navarrete‐Dechent, Sebastián Podlipnik, Emmanouil Chousakos, Iva Crnaric, Jovana Majstorović, Linda Alhajwan, Tanya Foreman, Sandra Peternel, Sergei Sarap, İrem Özdemir, Raymond L. Barnhill, Mar Llamas‐Velasco, Gabriela Poch, Sören Korsing, Wiebke Sondermann, Frank Friedrich Gellrich, Markus V. Heppt, Michael Erdmann, Sebastian Haferkamp, Konstantin Drexler, Matthias Goebeler, Bastian Schilling, Jochen Utikal, Kamran Ghoreschi, Stefan Fröhling, Eva Krieghoff‐Henning, Alexander Salava, Alexander Thiem, Alexandris Dimitrios, Amr Mohammad Ammar, Ana Sanader Vučemilović, Andrea Miyuki Yoshimura, Andzelka Ilieva, Anja Gesierich, Antonia Reimer‐Taschenbrecker, Antonios G.A. Kolios, Arturs Kaļva, Arzu Ferhatosmanoğlu, Aude Beyens, Claudia Pföhler, Dilara Ilhan Erdil, Dobrila Jovanovic, Emöke Rácz, Falk G. Bechara, Federico Vaccaro, Florentia Dimitriou, Günel Rasulova, Hülya Cenk, Irem Yanatma, Isabel Kolm, Isabelle Hoorens, Iskra Petrovska Sheshova, Ivana Jocic, Jana Knuever, Janik Fleißner, Janis Thamm, Johan Dahlberg, Juan José Lluch‐Galcerá, Juan Sebastián Andreani Figueroa, Julia Holzgruber, Julia Welzel, Katerina Damevska, Kristine Elisabeth Mayer, Lara Valeska Maul, Laura Garzona-Navas, Laura Isabell Bley, Laurenz Schmitt, Lena Reipen, Lidia Shafik, Lidija Petrovska, Linda Golle, Luise Jopen, Magda Gogilidze, Maria Rosa Burg, Martha Alejandra Morales‐Sánchez, Martyna Sławińska, Miriam Mengoni, Miroslav Dragolov, N. Iglesias-Pena, Nina Booken, Nkechi Anne Enechukwu, Oana‐Diana Persa, Olumayowa Abimbola Oninla, Panagiota Theofilogiannakou, Paula Kage, Roque Rafael Oliveira Neto, Rosario Peralta, Rym Afiouni, Sandra Schuh, Saskia Schnabl-Scheu, Seçil Vural, Sharon Hudson ほか 24 名 - Nature Communications 2024 被引用: 151

  11. Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task

    著者: Titus J. Brinker, Achim Hekler, Alexander Enk, Joachim Klode, Axel Hauschild, Carola Berking, Bastian Schilling, Sebastian Haferkamp, Dirk Schadendorf, Tim Holland‐Letz, Jochen Utikal, Christof von Kalle, Wiebke Ludwig‐Peitsch, Judith Sirokay, Lucie Heinzerling, Magarete Albrecht, Katharina Baratella, Lena Bischof, Eleftheria Chorti, Anna Dith, Christina Drusio, Nina Giese, Emmanouil Gratsias, Klaus Griewank, Sandra Hallasch, Zdenka Hanhart, Saskia Herz, Katja Hohaus, Philipp Jansen, Finja Jockenhöfer, Theodora Kanaki, Sarah Knispel, Katja Leonhard, Anna Martaki, Liliana Matei, Johanna Matull, Alexandra Olischewski, Maximilian Petri, Jan‐Malte Placke, Simon Raub, Katrin Salva, Swantje Schlott, Elsa Sody, Nadine Steingrube, Ingo Stoffels, Selma Ugurel, Anne Zaremba, Christoffer Gebhardt, Nina Booken, Maria Christolouka, Kristina Buder‐Bakhaya, Therezia Bokor‐Billmann, Alexander Enk, Patrick Gholam, Holger Hänßle, Martin Salzmann, Sarah K. Schäfer, Knut Schäkel, Timo Schank, Ann‐Sophie Bohne, Sophia Deffaa, Katharina Drerup, Friederike Egberts, Anna‐Sophie Erkens, Benjamin Ewald, Sandra Falkvoll, Sascha Gerdes, Viola Harde, Axel Hauschild, Marion Jost, Katja Kosova, Laetitia Messinger, Malte Metzner, Kirsten Morrison, Rogina Motamedi, Anja Pinczker, Anne Rosenthal, Natalie Scheller, Thomas Schwarz, Dora Stölzl, Federieke Thielking, Elena Tomaschewski, Ulrike Wehkamp, Michael Weichenthal, Oliver Wiedow, Claudia Bär, Sophia Bender-Säbelkampf, Marc Horbrügger, Ante Karoglan, Luise Kraas, Jörg Faulhaber, Cyrill Géraud, Ze Guo, Philipp Koch, Miriam Linke, Nolwenn Maurier, Verena Müller, Benjamin Thomas, Jochen Utikal, Ali Saeed M. Alamri ほか 34 名 - European Journal of Cancer 2019 被引用: 589

  12. Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts

    著者: Sarah Haggenmüller, Roman C. Maron, Achim Hekler, Jochen Utikal, Catarina Barata, Raymond L. Barnhill, Helmut Beltraminelli, Carola Berking, Brigid Betz‐Stablein, Andreas Blum, Stephan Alexander Braun, Richard Carr, Marc Combalia, María Teresa Fernández‐Figueras, Gerardo Ferrara, Sylvie Fraitag, Lars E. French, Frank Friedrich Gellrich, Kamran Ghoreschi, Matthias Goebeler, Pascale Guitera, Holger A. Haenssle, Sebastian Haferkamp, Lucie Heinzerling, Markus V. Heppt, Franz J. Hilke, Sarah Hobelsberger, Dieter Krahl, Heinz Kutzner, Aimilios Lallas, Konstantinos Liopyris, Mar Llamas‐Velasco, Josep Malvehy, Friedegund Meier, F. Max Müller, Alexander A. Navarini, Cristián Navarrete‐Dechent, Antonio Perasole, Gabriela Poch, Sebastián Podlipnik, Luis Requena, Veronica Rotemberg, Andrea Saggini, Omar P. Sangüeza, Carlos Santonja, Dirk Schadendorf, Bastian Schilling, Max Schlaak, Justin Gabriel Schlager, Mildred Sergon, Wiebke Sondermann, H. Peter Soyer, Hans Starz, Wilhelm Stolz, Esmeralda Vale, Wolfgang Weyers, Alexander Zink, Eva Krieghoff‐Henning, Jakob Nikolas Kather, Christof von Kalle, Daniel B. Lipka, Stefan Fröhling, Axel Hauschild, Harald Kittler, Titus J. Brinker - European Journal of Cancer 2021 被引用: 247

  13. Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma

    著者: Keith T. Flaherty, Caroline Robert, Peter Hersey, Paul Nathan, Claus Garbe, Mohammed Milhem, Lev Demidov, Jessica C. Hassel, Piotr Rutkowski, Peter Mohr, Reinhard Dummer, Uwe Trefzer, James Larkin, Jochen Utikal, Brigitte Dréno, Marta Nyakas, Mark R. Middleton, Jürgen C. Becker, Michelle Casey, Laurie Sherman, Frank Wu, Danièle Ouellet, Anne‐Marie Martin, Kiran Klaus Patel, Dirk Schadendorf - New England Journal of Medicine 2012 被引用: 2,141

  14. Skin Cancer Classification Using Convolutional Neural Networks: Systematic Review

    著者: Titus J. Brinker, Achim Hekler, Jochen Utikal, Niels Grabe, Dirk Schadendorf, Joachim Klode, Carola Berking, Theresa Steeb, Alexander Enk, Christof von Kalle - Journal of Medical Internet Research 2018 被引用: 488

  15. Deep neural networks are superior to dermatologists in melanoma image classification

    著者: Titus J. Brinker, Achim Hekler, Alexander Enk, Carola Berking, Sebastian Haferkamp, Axel Hauschild, Michael Weichenthal, Joachim Klode, Dirk Schadendorf, Tim Holland‐Letz, Christof von Kalle, Stefan Fröhling, Bastian Schilling, Jochen Utikal - European Journal of Cancer 2019 被引用: 410

  16. Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial

    著者: Georgina V. Long, Daniil Stroyakovskiy, Helen Gogas, E. Levchenko, Filippo de Braud, James Larkin, Claus Garbe, Thomas Jouary, Axel Hauschild, Jean‐Jacques Grob, Vanna Chiarion‐Sileni, Célèste Lebbé, Mario Mandalà, Michael Millward, Ana Arance, Igor Bondarenko, John B.A.G. Haanen, Johan Hansson, Jochen Utikal, Virginia Ferraresi, Н. В. Коваленко, Peter Mohr, Volodymr Probachai, Dirk Schadendorf, Paul Nathan, Caroline Robert, Antoni Ribas, Douglas J. DeMarini, Jhangir G Irani, S. Swann, Jeffrey J. Legos, Fan Jin, Bijoyesh Mookerjee, Keith T. Flaherty - The Lancet 2015 被引用: 1,386

  17. Myeloid-Derived Suppressor Cells Hinder the Anti-Cancer Activity of Immune Checkpoint Inhibitors

    著者: Rebekka Weber, Viktor Fleming, Xiaoying Hu, Vasyl S. Nagibin, Christopher Groth, Peter Altevogt, Jochen Utikal, Viktor Umansky - Frontiers in Immunology 2018 被引用: 551

  18. Superior skin cancer classification by the combination of human and artificial intelligence

    著者: Achim Hekler, Jochen Utikal, Alexander Enk, Axel Hauschild, Michael Weichenthal, Roman C. Maron, Carola Berking, Sebastian Haferkamp, Joachim Klode, Dirk Schadendorf, Bastian Schilling, Tim Holland‐Letz, Benjamin Izar, Christof von Kalle, Stefan Fröhling, Titus J. Brinker, Laurenz Schmitt, Wiebke K. Peitsch, Friederike Hoffmann, Jürgen C. Becker, Christina Drusio, Philipp Jansen, Joachim Klode, Georg Lodde, Stefanie Sammet, Dirk Schadendorf, Wiebke Sondermann, Selma Ugurel, Jeannine Zader, Alexander Enk, Martin Salzmann, Sarah K. Schäfer, Knut Schäkel, Julia K. Winkler, Priscilla Wölbing, Hiba Asper, Ann‐Sophie Bohne, Victoria Brown, Bianca Burba, Sophia Deffaa, Cecilia Dietrich, Matthias Dietrich, Katharina Drerup, Friederike Egberts, Anna‐Sophie Erkens, Salim Greven, Viola Harde, Marion Jost, Merit Kaeding, Katharina Kosova, S. Lischner, Maria Maagk, Anna Laetitia Messinger, Malte Metzner, Rogina Motamedi, Ann-Christine Rosenthal, Ulrich Seidl, Jana Stemmermann, Kaspar Torz, Juliana Giraldo Velez, Jennifer Haiduk, Mareike Alter, Claudia Bär, Paul Bergenthal, Anne Gerlach, Christian Holtorf, Ante Karoglan, Sophie Kindermann, Luise Kraas, Moritz Felcht, Maria Rita Gaiser, Claus‐Detlev Klemke, Hjalmar Kurzen, Thomas Leibing, Verena Müller, Raphael Reinhard, Jochen Utikal, Franziska Winter, Carola Berking, Laurie Eicher, Daniela Hartmann, Markus V. Heppt, Katharina Kilian, Sebastian Krammer, Diana Lill, Anne‐Charlotte Niesert, Eva Oppel, Elke Sattler, Sonja Senner, Jens Wallmichrath, Hans Wolff, Anja Gesierich, Tina Giner, Valerie Glutsch, Andreas Kerstan, Dagmar Presser, Philipp Schrüfer, Patrick Schummer, Ina Stolze, Judith Weber ほか 5 名 - European Journal of Cancer 2019 被引用: 354

  19. Gastrointestinal cancer classification and prognostication from histology using deep learning: Systematic review

    著者: Sara Kuntz, Eva Krieghoff‐Henning, Jakob Nikolas Kather, Tanja Jutzi, Julia Höhn, Lennard Kiehl, Achim Hekler, Elizabeth Alwers, Christof von Kalle, Stefan Fröhling, Jochen Utikal, Hermann Brenner, Michael Hoffmeister, Titus J. Brinker - European Journal of Cancer 2021 被引用: 191

  20. SOX2 in development and cancer biology

    著者: Daniel Novak, Laura Hüser, Jonathan J. Elton, Viktor Umansky, Peter Altevogt, Jochen Utikal - Seminars in Cancer Biology 2019 被引用: 389

  21. Enhancing immunotherapy response in melanoma: myeloid-derived suppressor cells as a therapeutic target

    著者: Feyza Gül Özbay Kurt, Samantha Lasser, Ihor Arkhypov, Jochen Utikal, Viktor Umansky - Journal of Clinical Investigation 2023 被引用: 101

  22. The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression

    著者: Viktor Umansky, C Blattner, Christoffer Gebhardt, Jochen Utikal - Vaccines 2016 被引用: 441

  23. Deep learning outperformed 11 pathologists in the classification of histopathological melanoma images

    著者: Achim Hekler, Jochen Utikal, Alexander Enk, Wiebke Solaß, Max Schmitt, Joachim Klode, Dirk Schadendorf, Wiebke Sondermann, Cindy Franklin, Felix Bestvater, Michael J. Flaig, Dieter Krahl, Christof von Kalle, Stefan Fröhling, Titus J. Brinker - European Journal of Cancer 2019 被引用: 280

  24. Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study

    著者: G.V. Long, K.T. Flaherty, Daniil Stroyakovskiy, Helen Gogas, E. Levchenko, Filippo de Braud, J. Larkin, C. Garbe, T. Jouary, A. Hauschild, Vanna Chiarion‐Sileni, C. Lebbe, M. Mandalá, M. Millward, Ana Arance, Igor Bondarenko, J.B.A.G. Haanen, J. Hansson, Jochen Utikal, Virginia Ferraresi, P. Mohr, V. Probachai, Dirk Schadendorf, Paul Nathan, C. Robert, A. Ribas, M.A. Davies, S.R. Lane, J.J. Legos, B. Mookerjee, Jean‐Jacques Grob - Annals of Oncology 2017 被引用: 652