John F.X. Diffley
1986–2025 年に発表
- 別表記
- John F. X. Diffley
- 101
- 論文数
- 19,718
- 被引用数
- 78
- h 指数
- 99
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology85%
- Medicine10.9%
- Agricultural and Biological Sciences1.4%
- Computer Science0.7%
- Immunology and Microbiology0.7%
- Neuroscience0.3%
- その他1%
トピック
- DNA Repair Mechanisms21%
- Genomics and Chromatin Dynamics10%
- Microtubule and mitosis dynamics7.8%
- Cancer-related Molecular Pathways4.3%
- Fungal and yeast genetics research4.2%
- CRISPR and Genetic Engineering3.5%
- その他49.2%
共著者
- Alessandro Costa12
- Lucy S. Drury12
- Berta Canal11
- Karim Labib11
- Florian Weissmann8
- Michael Howell8
- Jingkun Zeng7
- Mary Wu7
- Rachel Ulferts7
- Rupert Beale7
- Tom Deegan7
- Allison W. McClure6
- Anne Early6
- Bruce Stillman6
- Andrea Nans5
- Jennifer C. Milligan5
- José Antonio Tercero5
- Julia F. Greiwe5
- Julie H. Cocker5
- Max E. Douglas5
- Agustina P. Bertolin4
- Chew Theng Lim4
- Corrado Santocanale4
- Dirk Remus4
全論文
- The Initiation of Eukaryotic DNA Replication
著者: Alessandro Costa, John F.X. Diffley - Annual Review of Biochemistry 2022 被引用: 246
- Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
著者: Jingkun Zeng, Stephanie A. Hills, Eiko Ozono, John F.X. Diffley - Cell 2023 被引用: 150
- Regulated eukaryotic DNA replication origin firing with purified proteins
著者: Joseph T.P. Yeeles, Tom Deegan, Agnieszka Janska, Anne Early, John F.X. Diffley - Nature 2015 被引用: 530
- How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication
著者: Joseph T.P. Yeeles, Agnieska Janska, Anne Early, John F.X. Diffley - Molecular Cell 2016 被引用: 380
- Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing
著者: Dirk Remus, Fabienne Beuron, Gökhan Tolun, Jack D. Griffith, Edward P. Morris, John F.X. Diffley - Cell 2009 被引用: 697
- The mechanism of eukaryotic CMG helicase activation
著者: Max E. Douglas, Ferdos Abid Ali, Alessandro Costa, John F.X. Diffley - Nature 2018 被引用: 288
- Mechanism of replication origin melting nucleated by CMG helicase assembly
著者: Jacob S. Lewis, Marta H Gross, Joana S. Sousa, Sarah S. Henrikus, Julia F. Greiwe, Andrea Nans, John F.X. Diffley, Alessandro Costa - Nature 2022 被引用: 113
- Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM
著者: Thomas C. R. Miller, Julia Locke, Julia F. Greiwe, John F.X. Diffley, Alessandro Costa - Nature 2019 被引用: 151
- ATPase-dependent quality control of DNA replication origin licensing
著者: Jordi Frigola, Dirk Remus, Amina Mehanna, John F.X. Diffley - Nature 2013 被引用: 234
- Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates
著者: Christoph F. Kurat, Joseph T.P. Yeeles, Harshil Patel, Anne Early, John F.X. Diffley - Molecular Cell 2016 被引用: 259
- Positive Supercoiling of Mitotic DNA Drives Decatenation by Topoisomerase II in Eukaryotes
著者: Jonathan Baxter, Nicholas Sen, V. López Martínez, M. E. Monturus De Carandini, Jorge B. Schvartzman, John F.X. Diffley, Luís Aragón - Science 2011 被引用: 176
- Origin Licensing Requires ATP Binding and Hydrolysis by the MCM Replicative Helicase
著者: Gideon Coster, Jordi Frigola, Fabienne Beuron, Edward P. Morris, John F.X. Diffley - Molecular Cell 2014 被引用: 133
- Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading
著者: Gideon Coster, John F.X. Diffley - Science 2017 被引用: 128
- Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
著者: Allison W. McClure, John F.X. Diffley - eLife 2021 被引用: 57
- Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase
著者: Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F.X. Diffley, Alessandro Costa - Nature Structural & Molecular Biology 2021 被引用: 50
- A replication fork determinant for the establishment of sister chromatid cohesion
著者: Masashi Minamino, Céline Bouchoux, Berta Canal, John F.X. Diffley, Frank Uhlmann - Cell 2023 被引用: 39
- Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint
著者: José Antonio Tercero, John F.X. Diffley - Nature 2001 被引用: 671
- Mrc1 transduces signals of DNA replication stress to activate Rad53
著者: Annette A. Alcasabas, Alexander J. Osborn, Jeff Bachant, Fenghua Hu, Petra Werler, Kristine Bousset, Kanji Furuya, John F.X. Diffley, Antony M. Carr, Stephen J. Elledge - Nature Cell Biology 2001 被引用: 528
- DNA Replication and Oncogene-Induced Replicative Stress
著者: Stephanie A. Hills, John F.X. Diffley - Current Biology 2014 被引用: 386
- Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase
著者: Jingkun Zeng, Florian Weissmann, Agustina P. Bertolin, Viktor Posse, Berta Canal, Rachel Ulferts, Mary Wu, Ruth Harvey, Saira Hussain, Jennifer C. Milligan, Chloë Roustan, Annabel Borg, Laura E. McCoy, Lucy S. Drury, Svend Kjær, John W. McCauley, Michael Howell, Rupert Beale, John F.X. Diffley - Biochemical Journal 2021 被引用: 78
- Cdt1 stabilizes an open MCM ring for helicase loading
著者: Jordi Frigola, Jun He, K. Kinkelin, Valerie E. Pye, Ludovic Renault, Max E. Douglas, Dirk Remus, Peter Cherepanov, Alessandro Costa, John F.X. Diffley - Nature Communications 2017 被引用: 95
- MCM: one ring to rule them all
著者: Tom Deegan, John F.X. Diffley - Current Opinion in Structural Biology 2016 被引用: 177
- Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome
著者: Panchali Goswami, Ferdos Abid Ali, Max E. Douglas, Julia Locke, Andrew G. Purkiss, Agnieszka Janska, Patrik Eickhoff, Anne Early, Andrea Nans, Alan C. M. Cheung, John F.X. Diffley, Alessandro Costa - Nature Communications 2018 被引用: 129
- CDKs Promote DNA Replication Origin Licensing in Human Cells by Protecting Cdc6 from APC/C-Dependent Proteolysis
著者: Niels Mailand, John F.X. Diffley - Cell 2005 被引用: 340
