John J. O’Shea
1984–2025 年に発表
- 別表記
- John J. O'Shea
- 224
- 論文数
- 70,417
- 被引用数
- 134
- h 指数
- 221
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine39.5%
- Immunology and Microbiology35.2%
- Biochemistry, Genetics and Molecular Biology19.6%
- Neuroscience2.5%
- Agricultural and Biological Sciences0.6%
- Pharmacology, Toxicology and Pharmaceutics0.5%
- その他2.1%
トピック
- Immune Cell Function and Interaction8.7%
- T-cell and B-cell Immunology6.6%
- Cytokine Signaling Pathways and Interactions5.1%
- Immunotherapy and Immune Responses3.2%
- Psoriasis: Treatment and Pathogenesis2.9%
- IL-33, ST2, and ILC Pathways2.8%
- その他70.7%
共著者
- Yuka Kanno61
- Arian Laurence46
- Massimo Gadina40
- Hong‐Wei Sun27
- Alejandro V. Villarino25
- Golnaz Vahedi21
- Kiyoshi Hirahara19
- Wendy T. Watford19
- Giuseppe Sciumè15
- Han‐Yu Shih15
- Stephen R. Brooks13
- Hayato Takahashi12
- James A. Johnston12
- Lai Wei12
- Chen Yao11
- Daniella M. Schwartz11
- Kamran Ghoreschi11
- Lothar Hennighausen11
- Yohei Mikami11
- Cristina M. Tato10
- David M. Frucht10
- Fred P. Davis9
- Jérôme Galon9
- Kan Jiang9
全論文
- The JAK-STAT pathway at 30: Much learned, much more to do
著者: Rachael L. Philips, Yuxin Wang, HyeonJoo Cheon, Yuka Kanno, Massimo Gadina, Vittorio Sartorelli, Curt M. Horvath, James Darnell, George R. Stark, John J. O’Shea - Cell 2022 被引用: 723
- The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention
著者: John J. O’Shea, Daniella M. Schwartz, Alejandro V. Villarino, Massimo Gadina, Iain B. McInnes, Arian Laurence - Annual Review of Medicine 2015 被引用: 1,577
- Mechanisms and consequences of Jak–STAT signaling in the immune system
著者: Alejandro V. Villarino, Yuka Kanno, John J. O’Shea - Nature Immunology 2017 被引用: 1,205
- JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
著者: Daniella M. Schwartz, Yuka Kanno, Alejandro V. Villarino, Michael M. Ward, Massimo Gadina, John J. O’Shea - Nature Reviews Drug Discovery 2017 被引用: 1,209
- Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach
著者: Yoshiya Tanaka, Yiming Luo, John J. O’Shea, Shingo Nakayamada - Nature Reviews Rheumatology 2022 被引用: 487
- Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
著者: Chen Yao, Hong‐Wei Sun, Neal E. Lacey, Yun Ji, E. Ashley Moseman, Han‐Yu Shih, Elisabeth F. Heuston, Martha Kirby, Stacie M. Anderson, Jun Cheng, Omar Khan, Robin Handon, Julie Reilley, Jessica Fioravanti, Jinhui Hu, Selamawit Gossa, E. John Wherry, Luca Gattinoni, Dorian B. McGavern, John J. O’Shea, Pamela L. Schwartzberg, Tuoqi Wu - Nature Immunology 2019 被引用: 567
- JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease
著者: John J. O’Shea, Robert M. Plenge - Immunity 2012 被引用: 1,141
- JAKs and STATs in Immunity, Immunodeficiency, and Cancer
著者: John J. O’Shea, Steven M. Holland, Louis M. Staudt - New England Journal of Medicine 2013 被引用: 920
- Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair
著者: Jonathan L. Linehan, Oliver J. Harrison, Seong-Ji Han, Allyson L. Byrd, Ivan Vujkovic-Cvijin, Alejandro V. Villarino, Shurjo K. Sen, Jahangheer Shaik, Margery Smelkinson, Samira Tamoutounour, Nicholas Collins, Nicolas Bouladoux, Amiran Dzutsev, Stephan P. Rosshart, Jesse H. Arbuckle, Chyung‐Ru Wang, Thomas M. Kristie, Barbara Rehermann, Giorgio Trinchieri, Jason M. Brenchley, John J. O’Shea, Yasmine Belkaid - Cell 2018 被引用: 456
- Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation
著者: Hiroyuki Nagashima, Tanel Mahlakõiv, Han‐Yu Shih, Fred P. Davis, Françoise Meylan, Yuefeng Huang, Oliver J. Harrison, Chen Yao, Yohei Mikami, Joseph F. Urban, Kathleen M. Caron, Yasmine Belkaid, Yuka Kanno, David Artis, John J. O’Shea - Immunity 2019 被引用: 312
- Generation of pathogenic TH17 cells in the absence of TGF-β signalling
著者: Kamran Ghoreschi, Arian Laurence, Xiang‐Ping Yang, Cristina M. Tato, Mandy J. McGeachy, Joanne E. Konkel, Haydeé L. Ramos, Lai Wei, Todd S. Davidson, Nicolas Bouladoux, John R. Grainger, Qian Chen, Yuka Kanno, Wendy T. Watford, Hong‐Wei Sun, Gérard Eberl, Ethan M. Shevach, Yasmine Belkaid, Daniel J. Cua, Wanjun Chen, John J. O’Shea - Nature 2010 被引用: 1,385
- The γc Family of Cytokines: Basic Biology to Therapeutic Ramifications
著者: Warren J. Leonard, Jian‐Xin Lin, John J. O’Shea - Immunity 2019 被引用: 382
- BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells
著者: Chen Yao, Guohua Lou, Hong‐Wei Sun, Ziang Zhu, Yi Sun, Zeyu Chen, Daniel Chauss, E. Ashley Moseman, Jun Cheng, Marc D’Antonio, Wangke Shi, Junwei Shi, Kohei Kometani, Tomohiro Kurosaki, E. John Wherry, Behdad Afzali, Luca Gattinoni, Yuwen Zhu, Dorian B. McGavern, John J. O’Shea, Pamela L. Schwartzberg, Tuoqi Wu - Nature Immunology 2021 被引用: 200
- An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
著者: Scott Canna, Adriana A. de Jesus, Sushanth Gouni, Stephen R. Brooks, Bernadette Marrero, Yin Liu, Michael A. DiMattia, Kristien J.M. Zaal, Gina A. Montealegre Sanchez, Hanna Kim, Dawn Chapelle, Nicole Plass, Yan Huang, Alejandro V. Villarino, Angélique Biancotto, Thomas A. Fleisher, Joseph A. Duncan, John J. O’Shea, Susanne M. Benseler, Alexei A. Grom, Zuoming Deng, Ronald M. Laxer, Raphaela Goldbach‐Mansky - Nature Genetics 2014 被引用: 735
- Janus kinases in immune cell signaling
著者: Kamran Ghoreschi, Arian Laurence, John J. O’Shea - Immunological Reviews 2009 被引用: 1,141
- Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases
著者: Daniella M. Schwartz, Michael Bonelli, Massimo Gadina, John J. O’Shea - Nature Reviews Rheumatology 2015 被引用: 643
- Mechanisms of Jak/STAT Signaling in Immunity and Disease
著者: Alejandro V. Villarino, Yuka Kanno, John R. Ferdinand, John J. O’Shea - The Journal of Immunology 2014 被引用: 548
- Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus
著者: Sarfaraz Hasni, Sarthak Gupta, Michael A. Davis, Elaine Poncio, Yenealem Temesgen‐Oyelakin, Philip M. Carlucci, Xinghao Wang, Mohammad Naqi, Martin P. Playford, Rishi R. Goel, Xiaobai Li, Ann Biehl, Isabel Ochoa-Navas, Zerai Manna, Yinghui Shi, Donald E. Thomas, Jinguo Chen, Angélique Biancotto, Richard Apps, Foo Cheung, Yuri Kotliarov, Ashley L. Babyak, Huizhi Zhou, Rongye Shi, Katie Stagliano, Wanxia Li Tsai, Laura Vian, Nathalia Gazaniga, Valentina Giudice, Shajia Lu, Stephen R. Brooks, Meggan Mackay, Peter K. Gregersen, Nehal N. Mehta, Alan T. Remaley, Betty Diamond, John J. O’Shea, Massimo Gadina, Mariana J. Kaplan - Nature Communications 2021 被引用: 197
- Selectivity, efficacy and safety of JAKinibs: new evidence for a still evolving story
著者: Michael Bonelli, Andreas Kerschbaumer, Kastriot Kastrati, Kamran Ghoreschi, Massimo Gadina, Leonhard X. Heinz, Josef S Smolen, Daniel Aletaha, John J. O’Shea, Arian Laurence - Annals of the Rheumatic Diseases 2023 被引用: 143
- The Janus kinases (Jaks)
著者: Kunihiro Yamaoka, Pipsa Saharinen, Marko Pesu, Vance Holt, Olli Silvennoinen, John J. O’Shea - Genome biology 2004 被引用: 619
- Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation
著者: Arian Laurence, Cristina M. Tato, Todd S. Davidson, Yuka Kanno, Zhi Chen, Zhengju Yao, Rebecca B. Blank, Françoise Meylan, Richard M. Siegel, Lothar Hennighausen, Ethan M. Shevach, John J. O’Shea - Immunity 2007 被引用: 1,474
- Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4 + T Cells
著者: John J. O’Shea, William E. Paul - Science 2010 被引用: 1,358
- The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
著者: Mandy J McGeachy, Yi Chen, Cristina M. Tato, Arian Laurence, Barbara Joyce-Shaikh, Wendy M. Blumenschein, Terrill K. McClanahan, John J. O’Shea, Daniel J Cua - Nature Immunology 2009 被引用: 1,065
- JAKS AND STATS: Biological Implications
著者: Warren J. Leonard, John J. O’Shea - Annual Review of Immunology 1998 被引用: 1,819
