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John T. Isaacs

1977–2025 年に発表

130
論文数
24,510
被引用数
92
h 指数
129
i10 指数

被引用数

John T. Isaacs の年別被引用数1978 年: 被引用 1 件1979 年: 被引用 4 件1980 年: 被引用 2 件1981 年: 被引用 2 件1982 年: 被引用 2 件1983 年: 被引用 8 件1984 年: 被引用 9 件1985 年: 被引用 14 件1986 年: 被引用 9 件1987 年: 被引用 10 件1988 年: 被引用 17 件1989 年: 被引用 31 件1990 年: 被引用 36 件1991 年: 被引用 57 件1992 年: 被引用 109 件1993 年: 被引用 114 件1994 年: 被引用 145 件1995 年: 被引用 139 件1996 年: 被引用 191 件1997 年: 被引用 199 件1998 年: 被引用 188 件1999 年: 被引用 207 件2000 年: 被引用 229 件2001 年: 被引用 213 件2002 年: 被引用 185 件2003 年: 被引用 232 件2004 年: 被引用 238 件2005 年: 被引用 193 件2006 年: 被引用 225 件2007 年: 被引用 167 件2008 年: 被引用 158 件2009 年: 被引用 170 件2010 年: 被引用 148 件2011 年: 被引用 140 件2012 年: 被引用 150 件2013 年: 被引用 126 件2014 年: 被引用 139 件2015 年: 被引用 167 件2016 年: 被引用 178 件2017 年: 被引用 175 件2018 年: 被引用 159 件2019 年: 被引用 471 件2020 年: 被引用 467 件2021 年: 被引用 575 件2022 年: 被引用 351 件2023 年: 被引用 238 件2024 年: 被引用 379 件2025 年: 被引用 176 件2026 年: 被引用 2 件

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 3,059 件、この内訳の 37.8%中国: 引用元論文 698 件、この内訳の 8.6%イギリス: 引用元論文 457 件、この内訳の 5.6%ドイツ: 引用元論文 371 件、この内訳の 4.6%カナダ: 引用元論文 345 件、この内訳の 4.3%イタリア: 引用元論文 295 件、この内訳の 3.6%フランス: 引用元論文 254 件、この内訳の 3.1%日本: 引用元論文 246 件、この内訳の 3%オーストラリア: 引用元論文 218 件、この内訳の 2.7%オランダ: 引用元論文 182 件、この内訳の 2.3%スイス: 引用元論文 139 件、この内訳の 1.7%インド: 引用元論文 126 件、この内訳の 1.6%
0%37.8%その他 21.1%

機関

分野

  • Medicine55.2%
  • Biochemistry, Genetics and Molecular Biology35.2%
  • Immunology and Microbiology2.9%
  • Neuroscience1.9%
  • Engineering1.1%
  • Chemistry0.8%
  • その他2.9%

トピック

  • Prostate Cancer Treatment and Research11.3%
  • Prostate Cancer Diagnosis and Treatment3.9%
  • Cancer Cells and Metastasis3%
  • Cancer, Lipids, and Metabolism2.1%
  • Estrogen and related hormone effects2%
  • Hormonal and reproductive studies2%
  • その他75.7%

共著者

全論文

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  1. AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

    著者: Emmanuel S. Antonarakis, Changxue Lu, Hao Wang, Brandon Luber, Mari Nakazawa, Jeffrey C. Roeser, Yan Chen, Tabrez A. Mohammad, Yidong Chen, Helen Fedor, Tamara L. Lotan, Qizhi Zheng, Angelo M. De Marzo, John T. Isaacs, William B. Isaacs, Rosa Nadal, Channing J. Paller, Samuel R. Denmeade, Michael A. Carducci, Mario A. Eisenberger, Jun Luo - New England Journal of Medicine 2014 被引用: 2,687

  2. Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

    著者: Michael D. Nyquist, Alexandra Corella, Ilsa M. Coleman, Navonil De Sarkar, Arja Kaipainen, Gavin Ha, Roman Gulati, Lisa S. Ang, Payel Chatterjee, Jared M. Lucas, Colin C. Pritchard, Gail P. Risbridger, John T. Isaacs, Bruce Montgomery, Colm Morrissey, Eva Corey, Peter S. Nelson - Cell Reports 2020 被引用: 301

  3. Rationale Behind Targeting Fibroblast Activation Protein–Expressing Carcinoma-Associated Fibroblasts as a Novel Chemotherapeutic Strategy

    著者: W. Nathaniel Brennen, John T. Isaacs, Samuel R. Denmeade - Molecular Cancer Therapeutics 2012 被引用: 287

  4. Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer

    著者: W. Nathaniel Brennen, Yezi Zhu, Ilsa M. Coleman, Susan L. Dalrymple, Lizamma Antony, Radhika A. Patel, Brian Hanratty, Roshan Chikarmane, Alan K. Meeker, Shun Zheng, Jody E. Hooper, Jun Luo, Angelo M. De Marzo, Eva Corey, Jianfeng Xu, Srinivasan Yegnasubramanian, Michael C. Haffner, Peter S. Nelson, William G. Nelson, William B. Isaacs, John T. Isaacs - JCI Insight 2021 被引用: 57

  5. Concise Review: Mesenchymal Stem Cell-Based Drug Delivery: The Good, the Bad, the Ugly, and the Promise

    著者: Timothy Krueger, Daniel L.J. Thorek, Samuel R. Denmeade, John T. Isaacs, W. Nathaniel Brennen - Stem Cells Translational Medicine 2018 被引用: 239

  6. Engineering a Prostate-Specific Membrane Antigen–Activated Tumor Endothelial Cell Prodrug for Cancer Therapy

    著者: Samuel R. Denmeade, Annastasiah Mhaka, Dina Rosen, W. Nathaniel Brennen, Susan L. Dalrymple, Ingrid Dach, Claus Olesen, Bora Gürel, Angelo M. De Marzo, George Wilding, Michael A. Carducci, Craig A. Dionne, Jesper V. Møller, Poul Nissen, S. Brøgger Christensen, John T. Isaacs - Science Translational Medicine 2012 被引用: 217

  7. Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors

    著者: Yezi Zhu, Susan L. Dalrymple, Ilsa M. Coleman, Shun Zheng, Jianfeng Xu, Jody E. Hooper, Emmanuel S. Antonarakis, Angelo M. De Marzo, Alan K. Meeker, Peter S. Nelson, William B. Isaacs, Samuel R. Denmeade, Jun Luo, W. Nathaniel Brennen, John T. Isaacs - Oncogene 2020 被引用: 105

  8. Targeting Carcinoma-Associated Fibroblasts Within the Tumor Stroma With a Fibroblast Activation Protein-Activated Prodrug

    著者: W. Nathaniel Brennen, David Rosen, H. Wang, John T. Isaacs, Samuel R. Denmeade - JNCI Journal of the National Cancer Institute 2012 被引用: 184

  9. A history of prostate cancer treatment

    著者: Samuel R. Denmeade, John T. Isaacs - Nature reviews. Cancer 2002 被引用: 590

  10. Hedgehog signalling in prostate regeneration, neoplasia and metastasis

    著者: Sunil Karhadkar, G. Steven Bova, Nadia M. Abdallah, Surajit Dhara, Dale R. Gardner, Anirban Maitra, John T. Isaacs, David M. Berman, Philip A. Beachy - Nature 2004 被引用: 947

  11. Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: Results from a pilot clinical study

    著者: Michael T. Schweizer, Emmanuel S. Antonarakis, Hao Wang, A. Seun Ajiboye, Avery Spitz, Haiyi Cao, Jun Luo, Michael C. Haffner, Srinivasan Yegnasubramanian, Michael A. Carducci, Mario A. Eisenberger, John T. Isaacs, Samuel R. Denmeade - Science Translational Medicine 2015 被引用: 254

  12. Tumor‐infiltrating mesenchymal stem cells: Drivers of the immunosuppressive tumor microenvironment in prostate cancer?

    著者: Timothy Krueger, Daniel L.J. Thorek, Alan K. Meeker, John T. Isaacs, W. Nathaniel Brennen - The Prostate 2018 被引用: 87

  13. Supraphysiologic Testosterone Induces Ferroptosis and Activates Immune Pathways through Nucleophagy in Prostate Cancer

    著者: Rajendra Kumar, Janet Mendonca, Olutosin Owoyemi, Kavya Boyapati, Naiju Thomas, Suthicha Kanacharoen, Max Coffey, Deven Topiwala, Carolina Gomes, Busra Ozbek, Tracy Jones, Marc Rosen, Liang Dong, Sadie Wiens, W. Nathaniel Brennen, John T. Isaacs, Angelo M. De Marzo, Mark C. Markowski, Emmanuel S. Antonarakis, David Z. Qian, Kenneth J. Pienta, Drew M. Pardoll, Michael A. Carducci, Samuel R. Denmeade, Sushant K. Kachhap - Cancer Research 2021 被引用: 47

  14. Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

    著者: Jesse C. Patterson, Andreas Varkaris, Peter J.P. Croucher, Maya Ridinger, Susan L. Dalrymple, Mannan Nouri, Fang Xie, Shohreh Varmeh, Oliver Jonas, Matthew A. Whitman, Sen Chen, Saleh Rashed, Lovemore Makusha, Jun Luo, John T. Isaacs, Mark G. Erlander, David J. Einstein, Steven P. Balk, Michael B. Yaffe - Cancer Research 2022 被引用: 22

  15. Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression

    著者: Robert M. Hughes, Brian W. Simons, Hamda Khan, Rebecca L. Miller, Valentina Kugler, Samantha Torquato, Debebe Theodros, Michael C. Haffner, Tamara L. Lotan, Jessie Huang, Elai Davicioni, Steven S. An, Ryan C. Riddle, Daniel L.J. Thorek, Isla P. Garraway, Elana J. Fertig, John T. Isaacs, W. Nathaniel Brennen, Ben Ho Park, Paula J. Hurley - Cancer Research 2019 被引用: 85

  16. Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC

    著者: Laura A. Sena, Rajendra Kumar, David E. Sanin, Elizabeth A. Thompson, Dina Rosen, Susan L. Dalrymple, Lizamma Antony, Yuhan Yang, Carolina Gomes‐Alexandre, Jessica Hicks, Tracy Jones, Kiara Bowers, Jillian N. Eskra, Jennifer Meyers, Anuj Gupta, Alyza Skaist, Srinivasan Yegnasubramanian, Jun Luo, W. Nathaniel Brennen, Sushant K. Kachhap, Emmanuel S. Antonarakis, Angelo M. De Marzo, John T. Isaacs, Mark C. Markowski, Samuel R. Denmeade - Journal of Clinical Investigation 2022 被引用: 44

  17. A Phase I Study to Assess the Safety and Cancer-Homing Ability of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer

    著者: Michael T. Schweizer, Hao Wang, Trinity J. Bivalacqua, Alan W. Partin, Su Jin Lim, Carolyn G. Chapman, Rehab Abdallah, Oren Levy, Neil A. Bhowmick, Jeffrey M. Karp, Angelo De Marzo, John T. Isaacs, W. Nathaniel Brennen, Samuel R. Denmeade - Stem Cells Translational Medicine 2019 被引用: 122

  18. Tasquinimod Is an Allosteric Modulator of HDAC4 Survival Signaling within the Compromised Cancer Microenvironment

    著者: John T. Isaacs, Lizamma Antony, Susan L. Dalrymple, W. Nathaniel Brennen, Stephanie Gerber, Hans J. Hammers, Michel D. Wissing, Sushant K. Kachhap, Jun Luo, Li Xing, Per Björk, Anders Olsson, Anders Björk, Tomas Leanderson - Cancer Research 2012 被引用: 113

  19. Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics

    著者: John T. Isaacs, W. Nathaniel Brennen, S. Brøgger Christensen, Samuel R. Denmeade - Molecules 2021 被引用: 31

  20. The SERCA pump as a therapeutic target: Making a “smart bomb” for prostate cancer

    著者: Samuel R. Denmeade, John T. Isaacs - Cancer Biology & Therapy 2005 被引用: 240

  21. The Role of CD133 in Normal Human Prostate Stem Cells and Malignant Cancer-Initiating Cells

    著者: Donald J. Vander Griend, Wouter L. Karthaus, Susan L. Dalrymple, Alan K. Meeker, Angelo M. De Marzo, John T. Isaacs - Cancer Research 2008 被引用: 233

  22. Targeting thapsigargin towards tumors

    著者: Nhu Thi Quynh Doan, Eleonora S. Paulsen, Pankaj Sehgal, Jesper V. Møller, Poul Nissen, Samuel R. Denmeade, John T. Isaacs, Craig A. Dionne, S. Brøgger Christensen - Steroids 2014 被引用: 134

  23. Overcoming Stromal Barriers to Immuno-Oncological Responses via Fibroblast Activation Protein-Targeted Therapy

    著者: W. Nathaniel Brennen, Daniel L.J. Thorek, Wen Jiang, Timothy Krueger, Lizamma Antony, Samuel R. Denmeade, John T. Isaacs - Immunotherapy 2020 被引用: 30

  24. Etiology and disease process of benign prostatic hyperplasia

    著者: John T. Isaacs, Donald S. Coffey - The Prostate 1989 被引用: 555