Jorge Ghiso
1986–2024 年に発表
- 98
- 論文数
- 19,586
- 被引用数
- 79
- h 指数
- 96
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine65.9%
- Biochemistry, Genetics and Molecular Biology17.9%
- Neuroscience12.1%
- Immunology and Microbiology0.9%
- Materials Science0.7%
- Computer Science0.5%
- その他2%
トピック
- Alzheimer's disease research and treatments21.6%
- Cholinesterase and Neurodegenerative Diseases4.2%
- Computational Drug Discovery Methods3.9%
- Prion Diseases and Protein Misfolding3.9%
- Neuroinflammation and Neurodegeneration Mechanisms3.1%
- Dementia and Cognitive Impairment Research2.4%
- その他60.9%
共著者
- Blas Frangione62
- Agueda Rostagno32
- Berislav V. Zloković16
- Miguel Calero13
- Thomas Wısnıewskı11
- Rubén Vidal10
- Tamás Révész10
- Etsuro Matsubara9
- Gordon T. Plant9
- Jasmina B. Mačkić8
- Tammaryn Lashley8
- Janice L. Holton7
- Frances Prelli6
- J. Gordon McComb6
- Miguel A. Pappolla6
- Asok Kumar5
- E. Matsubara5
- Fabrizio Tagliavini5
- Yau‐Jan Chyan5
- Burkhard Pöeggeler4
- Erwin Cabrera4
- James R. Bading4
- Orso Bugiani4
- Silvia Fossati4
全論文
- Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier
著者: Masayoshi Shibata, Shinya Yamada, S. Ram Kumar, Miguel Calero, James R. Bading, Blas Frangione, David M. Holtzman, Carol A. Miller, Dudley K. Strickland, Jorge Ghiso, Berislav V. Zloković - Journal of Clinical Investigation 2000 被引用: 1,386
- RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain
著者: Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan, Barbara LaRue, Suzana Jovanović, Elizabeth Hogg, Deborah Welch, Lawrence Manness, Chang Lin, Jin Yu, Hong Zhu, Jorge Ghiso, Blas Frangione, Alan Stern, Ann Marie Schmidt, Don Armstrong, Bernd Arnold, Birgit Liliensiek, Peter P. Nawroth, Florence M. Hofman, Mark S. Kindy, David M. Stern, Berislav V. Zloković - Nature Medicine 2003 被引用: 1,397
- Potent Neuroprotective Properties against the Alzheimer β-Amyloid by an Endogenous Melatonin-related Indole Structure, Indole-3-propionic Acid
著者: Yau-Jan Chyan, Burkhard Pöeggeler, Rawhi Omar, Daniel G. Chain, Blas Frangione, Jorge Ghiso, Miguel A. Pappolla - Journal of Biological Chemistry 1999 被引用: 396
- Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host
著者: Melanie Meyer‐Luehmann, Janaky Coomaraswamy, Tristan Bolmont, Stephan A. Kaeser, Claudia Schaefer, Ellen Kilger, Anton Neuenschwander, Dorothée Abramowski, Pascal Frey, Anneliese L. Jaton, J. M. Vigouret, Paolo Paganetti, Dominic M. Walsh, Paul M. Mathews, Jorge Ghiso, Matthias Staufenbiel, Lary C. Walker, Mathias Jucker - Science 2006 被引用: 958
- Amyloid ion channels: A common structural link for protein-misfolding disease
著者: Arjan P. Quist, Ivo Doudevski, Hai Lin, Rushana Azimova, Douglas Ng, Blas Frangione, Bruce L. Kagan, Jorge Ghiso, Ratnesh Lal - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 被引用: 982
- Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain
著者: Ivan Alić, Pollyanna Goh, Aoife Murray, Erik Portelius, Eleni Gkanatsiou, Gillian Gough, Kin Y. Mok, David Koschut, Reinhard Brunmeir, Yee Jie Yeap, Niamh L. O’Brien, Jürgen Groet, Xiaowei Shao, Steven Havlicek, N. Ray Dunn, Hlin Kvartsberg, Gunnar Brinkmalm, Rosalyn Hithersay, Carla M. Startin, Sarah Hamburg, Margaret Phillips, Konstantin Pervushin, Mark Turmaine, David Wallon, Anne Rovelet‐Lecrux, Hilkka Soininen, Emanuela V. Volpi, Joanne E. Martin, Jia Nee Foo, David L. Becker, Agueda Rostagno, Jorge Ghiso, Željka Krsnik, Goran Šimić, Ivica Kostović, Dinko Mitrečić, André Strydom, Elizabeth Fisher, Frances K. Wiseman, Dean Nižetić, John Hardy, Victor L. J. Tybulewicz, Annette Karmiloff‐Smith, Paul T. Francis, Kaj Blennow, André Strydom, John Hardy, Henrik Zetterberg, Dean Nižetić, Dean Nižetić, Dean Nižetić - Molecular Psychiatry 2020 被引用: 123
- Systemic Catabolism of Alzheimer's Aβ40 and Aβ42
著者: Jorge Ghiso, Marcos Shayo, Miguel Calero, Douglas Ng, Yasushi Tomidokoro, Sam Gandy, Agueda Rostagno, Blas Frangione - Journal of Biological Chemistry 2004 被引用: 202
- The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain
著者: Silvia Fossati, Patrizia Giannoni, María E. Solesio, Sarah L. Cocklin, Erwin Cabrera, Jorge Ghiso, Agueda Rostagno - Neurobiology of Disease 2015 被引用: 106
- Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis
著者: Rebecca Parodi‐Rullán, Jorge Ghiso, Erwin Cabrera, Agueda Rostagno, Silvia Fossati - Aging Cell 2020 被引用: 71
- Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage
著者: Krystal Sotolongo, Jorge Ghiso, Agueda Rostagno - Alzheimer s Research & Therapy 2020 被引用: 69
- Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9
著者: Mar Hernández‐Guillamón, S. Mawhirt, Steven P. Blais, Joan Montaner, Thomas A. Neubert, Agueda Rostagno, Jorge Ghiso - Journal of Biological Chemistry 2015 被引用: 133
- Inhibition of Alzheimer β-Fibrillogenesis by Melatonin
著者: Miguel A. Pappolla, Peter Bozner, Claudio Soto, Haiyan Shao, Nickolaos K. Robakis, Michael G. Zagorski, Blas Frangione, Jorge Ghiso - Journal of Biological Chemistry 1998 被引用: 335
- Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
著者: Etsuro Matsubara, Tara Bryant‐Thomas, Javier Pacheco Quinto, Tracey L. Henry, Burkhard Pöeggeler, Donald E. Herbert, Felix Cruz-Sánchez, Yau‐Jan Chyan, Mark A. Smith, George Perry, Mikio Shoji, Kōji Abe, Anna Leone, Inge Grundke‐Ikbal, Glen L. Wilson, Jorge Ghiso, Christina Williams, Lorenzo M. Refolo, Miguel A. Pappolla - Journal of Neurochemistry 2003 被引用: 333
- A stop-codon mutation in the BRI gene associated with familial British dementia
著者: Rubén Vidal, Blas Frangione, Agueda Rostagno, Simon Mead, Tamás Révész, Gordon T. Plant, Jorge Ghiso - Nature 1999 被引用: 473
- Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies
著者: Tamás Révész, Janice L. Holton, Tammaryn Lashley, Gordon T. Plant, Blas Frangione, Agueda Rostagno, Jorge Ghiso - Acta Neuropathologica 2009 被引用: 298
- Melatonin Reverses the Profibrillogenic Activity of Apolipoprotein E4 on the Alzheimer Amyloid Aβ Peptide
著者: Burkhard Pöeggeler, Leticia Miravalle, Michael G. Zagorski, Thomas Wısnıewskı, Yau‐Jan Chyan, Yongbo Zhang, Haiyan Shao, Tara Bryant‐Thomas, Rubén Vidal, Blas Frangione, Jorge Ghiso, Miguel A. Pappolla - Biochemistry 2001 被引用: 151
- Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease
著者: Markus Britschgi, Christopher E. Olin, Hudson Johns, Yoshiko Takeda‐Uchimura, Melburne C. LeMieux, Kaspar Rufibach, Jayakumar Rajadas, H. Zhang, Beren H. Tomooka, William H. Robinson, Christopher M. Clark, Anne M. Fagan, Douglas Galasko, David M. Holtzman, Marek Jutel, Jeffrey Kaye, Cynthia A. Lemere, Jerzy Leszek, G. Li, Elaine R. Peskind, Joseph F. Quinn, Jerome A. Yesavage, Jorge Ghiso, Tony Wyss‐Coray - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 被引用: 199
- Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid β peptides
著者: Takahiko Tokuda, Miguel Calero, Etsuro Matsubara, Rubén Vidal, Asok Kumar, Bruno Permanne, Berislav V. Zloković, Jonathan D. Smith, Mary Jo LaDu, Agueda Rostagno, Blas Frangione, Jorge Ghiso - Biochemical Journal 2000 被引用: 265
- Cerebral Amyloid Angiopathies: A Pathologic, Biochemical, and Genetic View
著者: Tamás Révész, Jorge Ghiso, Tammaryn Lashley, Gordon T. Plant, Agueda Rostagno, Blas Frangione, Janice L. Holton - Journal of Neuropathology & Experimental Neurology 2003 被引用: 288
- Sporadic and Familial Cerebral Amyloid Angiopathies
著者: Tamás Révész, Janice L. Holton, Tammaryn Lashley, Gordon T. Plant, Agueda Rostagno, Jorge Ghiso, Blas Frangione - Brain Pathology 2002 被引用: 201
- Fate of Cerebrospinal Fluid‐Borne Amyloid β‐Peptide: Rapid Clearance into Blood and Appreciable Accumulation by Cerebral Arteries
著者: Jean‐François Ghersi‐Egea, Peter D. Gorevic, Jorge Ghiso, Blas Frangione, C. S. Patlak, J. D. Fenstermacher - Journal of Neurochemistry 1996 被引用: 221
- Circulating amyloid-β peptide crosses the blood–brain barrier in aged monkeys and contributes to Alzheimer's disease lesions
著者: Jasmina B. Mačkić, James R. Bading, Jorge Ghiso, Lary C. Walker, Thomas Wısnıewskı, Blas Frangione, Berislav V. Zloković - Vascular Pharmacology 2002 被引用: 137
- N-terminally truncated Aβ4-x proteoforms and their relevance for Alzheimer’s pathophysiology
著者: Agueda Rostagno, Erwin Cabrera, Tammaryn Lashley, Jorge Ghiso - Translational Neurodegeneration 2022 被引用: 25
- Production of the Alzheimer Amyloid β Protein by Normal Proteolytic Processing
著者: Mikio Shoji, Todd E. Golde, Jorge Ghiso, Tobun T. Cheung, Steven Estus, Lillian M. Shaffer, Xiao-Dan Cai, Deborah M. McKay, Ron Tintner, B Frangione, Steven G. Younkin - Science 1992 被引用: 1,445
