Kapil N. Bhalla
1984–2025 年に発表
- 160
- 論文数
- 29,872
- 被引用数
- 99
- h 指数
- 158
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology53.6%
- Medicine37.6%
- Immunology and Microbiology3.2%
- Neuroscience1.2%
- Agricultural and Biological Sciences0.9%
- Pharmacology, Toxicology and Pharmaceutics0.6%
- その他2.9%
トピック
- Cell death mechanisms and regulation5.5%
- Histone Deacetylase Inhibitors Research5%
- Acute Myeloid Leukemia Research4.1%
- Protein Degradation and Inhibitors3.6%
- Chronic Myeloid Leukemia Treatments2.9%
- Epigenetics and DNA Methylation2.6%
- その他76.3%
共著者
- Warren Fiskus55
- Courtney D. DiNardo34
- Tapan M. Kadia28
- Hagop M. Kantarjian22
- Naval Daver22
- Peter Atadja22
- Guillermo Garcia‐Manero21
- Koichi Takahashi21
- Marina Konopleva21
- Farhad Ravandi20
- Naveen Pemmaraju20
- Purva Bali17
- Gautam Borthakur16
- Christopher P. Mill15
- Rekha Rao15
- Elias Jabbour14
- Joseph D. Khoury14
- Sanam Loghavi13
- Keyur P. Patel12
- Hong‐Gang Wang11
- Ramadevi Nimmanapalli11
- Rashmi Kanagal‐Shamanna11
- Fei Guo10
- Jörge E. Cortes10
全論文
- Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics
著者: Kiyomi Morita, Feng Wang, Katharina Jahn, Tianyuan Hu, Tomoyuki Tanaka, Yuya Sasaki, Jack Kuipers, Sanam Loghavi, Sa A. Wang, Yuanqing Yan, Ken Furudate, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika J. Thompson, Keyur P. Patel, Carlos E. Bueso‐Ramos, Courtney D. DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jörge E. Cortes, Kapil N. Bhalla, Guillermo Garcia‐Manero, Hagop M. Kantarjian, Marina Konopleva, Daisuke Nakada, Nicholas E. Navin, Niko Beerenwinkel, P. Andrew Futreal, Koichi Takahashi - Nature Communications 2020 被引用: 387
- Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)
著者: Warren Fiskus, Steffen Boettcher, Naval Daver, Christopher P. Mill, Koji Sasaki, Christine Birdwell, John A. Davis, Koichi Takahashi, Tapan M. Kadia, Courtney D. DiNardo, Qi Jin, Yuan Qi, Xiaoping Su, Gerard M. McGeehan, Joseph D. Khoury, Benjamin L. Ebert, Kapil N. Bhalla - Blood Cancer Journal 2022 被引用: 139
- Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
著者: Jie Yang, Xuesong Liu, Kapil N. Bhalla, Caryn Naekyung Kim, Ana Maria Ibrado, Jiyang Cai, Tsung-I Peng, Dean P. Jones, Xiaodong Wang - Science 1997 被引用: 4,957
- Phase II Study of Venetoclax Added to Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia
著者: Tapan M. Kadia, Patrick K. Reville, Xuemei Wang, Caitlin R. Rausch, Gautam Borthakur, Naveen Pemmaraju, Naval Daver, Courtney D. DiNardo, Koji Sasaki, Ghayas C. Issa, Maro Ohanian, Guillermo Montalban‐Bravo, Nicholas J. Short, Nitin Jain, Alessandra Ferrajoli, Kapil N. Bhalla, Elias Jabbour, Koichi Takahashi, Rashmi Malla, Kelly Quagliato, Rashmi Kanagal‐Shamanna, Uday Popat, Michael Andreeff, Guillermo Garcia‐Manero, Marina Konopleva, Farhad Ravandi, Hagop M. Kantarjian - Journal of Clinical Oncology 2022 被引用: 114
- Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cells
著者: Yannan Jia, Lina Han, Cassandra L. Ramage, Zhe Wang, Connie C. Weng, Lei Yang, Simona Colla, Helen Ma, Weiguo Zhang, Michael Andreeff, Naval Daver, Nitin Jain, Naveen Pemmaraju, Kapil N. Bhalla, Satu Mustjoki, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Qi Zhang, Marina Konopleva - Haematologica 2023 被引用: 65
- Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1
著者: Warren Fiskus, Christopher P. Mill, Christine Birdwell, John A. Davis, Kaberi Das, Steffen Boettcher, Tapan M. Kadia, Courtney D. DiNardo, Koichi Takahashi, Sanam Loghavi, Michael Soth, Tim Heffernan, Gerard M. McGeehan, Xinjia Ruan, Xiaoping Su, Christopher R. Vakoc, Naval Daver, Kapil N. Bhalla - Blood Cancer Journal 2023 被引用: 54
- Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1
著者: Warren Fiskus, Naval Daver, Steffen Boettcher, Christopher P. Mill, Koji Sasaki, Christine Birdwell, John A. Davis, Kaberi Das, Koichi Takahashi, Tapan M. Kadia, Courtney D. DiNardo, Francis Burrows, Sanam Loghavi, Joseph D. Khoury, Benjamin L. Ebert, Kapil N. Bhalla - Leukemia 2022 被引用: 80
- Clinical experience with the BCL2‐inhibitor venetoclax in combination therapy for relapsed and refractory acute myeloid leukemia and related myeloid malignancies
著者: Courtney D. DiNardo, Caitlin R. Rausch, Christopher B. Benton, Tapan M. Kadia, Nitin Jain, Naveen Pemmaraju, Naval Daver, Wendy Covert, Kayleigh Marx, Morgan Mace, Elias Jabbour, Jörge E. Cortes, Guillermo Garcia‐Manero, Farhad Ravandi, Kapil N. Bhalla, Hagop M. Kantarjian, Marina Konopleva - American Journal of Hematology 2017 被引用: 437
- Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia
著者: Feng Wang, Kiyomi Morita, Courtney D. DiNardo, Ken Furudate, Tomoyuki Tanaka, Yuanqing Yan, Keyur P. Patel, Kyle J. MacBeth, Bin Wu, Guowen Liu, Mark G. Frattini, Jairo Matthews, Latasha Little, Curtis Gumbs, Xingzhi Song, Jianhua Zhang, Erika J. Thompson, Tapan M. Kadia, Guillermo Garcia‐Manero, Elias Jabbour, Farhad Ravandi, Kapil N. Bhalla, Marina Konopleva, Hagop M. Kantarjian, P. Andrew Futreal, Koichi Takahashi - Nature Communications 2021 被引用: 115
- The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance
著者: Alejandro Villagra, Fengdong Cheng, Hongwei Wang, Ildelfonso Suarez, Michelle Glozak, Michelle Maurin, Danny Nguyen, Kenneth L. Wright, Peter Atadja, Kapil N. Bhalla, Javier Pinilla‐Ibarz, Edward Seto, Eduardo M. Sotomayor - Nature Immunology 2008 被引用: 454
- Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML
著者: Ghayas C. Issa, Aram Bidikian, Sangeetha Venugopal, Marina Konopleva, Courtney D. DiNardo, Tapan M. Kadia, Gautam Borthakur, Elias Jabbour, Naveen Pemmaraju, Musa Yılmaz, Nicholas J. Short, Abhishek Maiti, Koji Sasaki, Lucia Masárová, Sherry Pierce, Koichi Takahashi, Guilin Tang, Sanam Loghavi, Keyur P. Patel, Michael Andreeff, Kapil N. Bhalla, Guillermo Garcia‐Manero, Farhad Ravandi, Hagop M. Kantarjian, Naval Daver - Blood Advances 2022 被引用: 56
- Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma
著者: Man Chun John, Saber Tadros, Alyssa Bouska, Tayla B. Heavican, Haopeng Yang, Qing Deng, Dalia Moore, Ariz Akhter, Keenan T. Hartert, Neeraj Jain, Jordan Showell, Sreejoyee Ghosh, Lesley Street, Marta Davidson, Christopher D. Carey, Joshua W.D. Tobin, Deepak Perumal, Julie M. Vose, Matthew A. Lunning, Aliyah R. Sohani, Benjamin J. Chen, Shannon M. Buckley, Loretta J. Nastoupil, R. Eric Davis, Jason R. Westin, Nathan Fowler, Samir Parekh, Maher K. Gandhi, Sattva S. Neelapu, Douglas A. Stewart, Kapil N. Bhalla, Javeed Iqbal, Timothy C. Greiner, Scott J. Rodig, Adnan Mansoor, Michael R. Green - Haematologica 2021 被引用: 74
- BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor
著者: Warren Fiskus, Jessica Piel, Michael P. Collins, Murphy Hentemann, Branko Cuglievan, Christopher P. Mill, Christine Birdwell, Kaberi Das, John A. Davis, Hanxi Hou, Antrix Jain, Anna Malovannaya, Tapan M. Kadia, Naval Daver, Koji Sasaki, Koichi Takahashi, Danielle Hammond, Patrick K. Reville, Jian Wang, Sanam Loghavi, Rwik Sen, Xinjia Ruan, Xiaoping Su, Lauren B. Flores, Courtney D. DiNardo, Kapil N. Bhalla - Blood 2024 被引用: 42
- Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 Inhibitors
著者: Ahmad S. Alotaibi, Musa Yılmaz, Rashmi Kanagal‐Shamanna, Sanam Loghavi, Tapan M. Kadia, Courtney D. DiNardo, Gautam Borthakur, Marina Konopleva, Sherry Pierce, Sa A. Wang, Guilin Tang, Veronica Guerra, Bachar Samra, Naveen Pemmaraju, Elias Jabbour, Nicholas J. Short, Ghayas C. Issa, Maro Ohanian, Guillermo Garcia‐Manero, Kapil N. Bhalla, Keyur P. Patel, Koichi Takahashi, Michael Andreeff, Jörge E. Cortes, Hagop M. Kantarjian, Farhad Ravandi, Naval Daver - Blood Cancer Discovery 2020 被引用: 97
- Characteristics and clinical outcomes of patients with myeloid malignancies and DDX41 variants
著者: Álex Bataller, Sanam Loghavi, Yoheved Gerstein, Alexandre Bazinet, Koji Sasaki, Kelly S. Chien, Danielle Hammond, Guillermo Montalban‐Bravo, Gautam Borthakur, Nicholas J. Short, Ghayas C. Issa, Tapan M. Kadia, Naval Daver, Guilin Tang, Andres Quesada, Keyur P. Patel, Farhad Ravandi, Warren Fiskus, Cristopher P Mill, Hagop M. Kantarjian, Kapil N. Bhalla, Guillermo Garcia‐Manero, Betül Oran, Courtney D. DiNardo - American Journal of Hematology 2023 被引用: 46
- BET protein proteolysis targeting chimera (PROTAC) exerts potent lethal activity against mantle cell lymphoma cells
著者: Baohua Sun, Warren Fiskus, Yimin Qian, Kimal Rajapakshe, Kanak Raina, Kevin Coleman, Andrew P. Crew, Angela Shen, Dyana T. Saenz, Christopher P. Mill, Agnieszka Nowak, Neeraj Jain, L Zhang, M Wang, Joseph D. Khoury, Cristian Coarfa, Craig M. Crews, Kapil N. Bhalla - Leukemia 2017 被引用: 178
- Targeting HSP90 for cancer therapy
著者: Devalingam Mahalingam, Ronan Swords, Jennifer S. Carew, Steffan T. Nawrocki, Kapil N. Bhalla, Francis J. Giles - British Journal of Cancer 2009 被引用: 316
- Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia
著者: Warren Fiskus, Nakhle S. Saba, Min Shen, Mondana Ghias, Jinyun Liu, Soumyasri Das Gupta, Lata Chauhan, Rekha Rao, Sumedha Gunewardena, Kevin Schorno, Christopher P. Austin, Kami J. Maddocks, John C. Byrd, Ari Melnick, Peng Huang, Adrian Wiestner, Kapil N. Bhalla - Cancer Research 2014 被引用: 246
- Effective therapy for AML with RUNX1 mutation by cotreatment with inhibitors of protein translation and BCL2
著者: Christopher P. Mill, Warren Fiskus, Courtney D. DiNardo, Christine Birdwell, John A. Davis, Tapan M. Kadia, Koichi Takahashi, Nicholas J. Short, Naval Daver, Maro Ohanian, Gautam Borthakur, Steven M. Kornblau, Michael R. Green, Yuan Qi, Xiaoping Su, Joseph D. Khoury, Kapil N. Bhalla - Blood 2021 被引用: 81
- Inhibition of Glycolysis in Cancer Cells: A Novel Strategy to Overcome Drug Resistance Associated with Mitochondrial Respiratory Defect and Hypoxia
著者: Rui‐Hua Xu, Hélène Pelicano, Yan Zhou, Jennifer S. Carew, Li Feng, Kapil N. Bhalla, Michael J. Keating, Peng Huang - Cancer Research 2005 被引用: 834
- Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells
著者: Warren Fiskus, S. Sharma, Biren Shah, Bryce P. Portier, Santhana G.T. Devaraj, Kathy Liu, Swaminathan P. Iyer, David J. Bearss, Kapil N. Bhalla - Leukemia 2014 被引用: 280
- Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90
著者: Purva Bali, Michael Pranpat, James E. Bradner, Maria E. Balasis, Warren Fiskus, Fei Guo, Kathy Rocha, Sandhya Kumaraswamy, Sandhya Boyapalle, Peter Atadja, Edward Seto, Kapil N. Bhalla - Journal of Biological Chemistry 2005 被引用: 749
- Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results
著者: Hagop M. Kantarjian, Francis J. Giles, Kapil N. Bhalla, Javier Pinilla‐Ibarz, Richard A. Larson, Norbert Gattermann, Oliver G. Ottmann, Andreas Hochhaus, Jerald P. Radich, Giuseppe Saglio, Timothy P. Hughes, Giovanni Martinelli, Dong-Wook Kim, Yaping Shou, Neil J. Gallagher, Rick E. Blakesley, Michele Baccarani, Jörge E. Cortes, Philipp D. le Coutre - Blood 2010 被引用: 379
- Clonal Evolution of Acute Myeloid Leukemia Revealed by High-Throughput Single-Cell Genomics
著者: Kiyomi Morita, Feng Wang, Katharina Jahn, Jack Kuipers, Yuanqing Yan, Jairo Matthews, Latasha Little, Curtis Gumbs, Shujuan Chen, Jianhua Zhang, Xingzhi Song, Erika J. Thompson, Keyur P. Patel, Carlos E. Bueso‐Ramos, Courtney D. DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jörge E. Cortes, Marina Konopleva, Kapil N. Bhalla, Guillermo Garcia‐Manero, Hagop M. Kantarjian, Niko Beerenwinkel, Nicholas E. Navin, P. Andrew Futreal, Koichi Takahashi - 2020 被引用: 67
