Karen O’Rourke
1985–2021 年に発表
- 別表記
- Karen O'Rourke
- 41
- 論文数
- 29,161
- 被引用数
- 39
- h 指数
- 40
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology68.7%
- Medicine16.8%
- Immunology and Microbiology10.1%
- Neuroscience1.4%
- Agricultural and Biological Sciences1.1%
- Nursing0.4%
- その他1.5%
トピック
- Inflammasome and immune disorders10.8%
- Cell death mechanisms and regulation9.2%
- interferon and immune responses4.6%
- Immune Response and Inflammation4.5%
- NF-κB Signaling Pathways4.2%
- Ubiquitin and proteasome pathways2.8%
- その他63.9%
共著者
- Vishva M. Dixit39
- Arul M. Chinnaiyan9
- Nobuhiko Kayagaki6
- Ingrid E. Wertz5
- Somasekar Seshagiri5
- Christopher C. Goodnow4
- David Arnott4
- Edward M. Bertram4
- Guy S. Salvesen4
- Irma B. Stowe4
- Jinfeng Liu4
- Lucy X. Morris4
- Merone Roose‐Girma4
- Michael Eby4
- Bettina L. Lee3
- David Dornan3
- Dorothy French3
- Eugene V. Koonin3
- F.W. Wolf3
- Guy G. Poirier3
- Jennie R. Lill3
- Jian Ni3
- Kim Newton3
- Meredith Sagolla3
全論文
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
著者: Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee, Karen O’Rourke, Keith R. Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose‐Girma, Qui Phung, Peter S. Liu, Jennie R. Lill, Hong Li, Jiansheng Wu, Sarah Kummerfeld, Juan Zhang, Wyne P. Lee, Scott J. Snipas, Guy S. Salvesen, Lucy X. Morris, Linda Fitzgerald, Yafei Zhang, Edward M. Bertram, Christopher C. Goodnow, Vishva M. Dixit - Nature 2015 被引用: 3,743
- NINJ1 mediates plasma membrane rupture during lytic cell death
著者: Nobuhiko Kayagaki, Opher S. Kornfeld, Bettina L. Lee, Irma B. Stowe, Karen O’Rourke, Qingling Li, Wendy Sandoval, Donghong Yan, Jing‐Qiong Kang, Min Xu, Juan Zhang, Wyne P. Lee, Brent S. McKenzie, Gözde Ulas, Jian Payandeh, Merone Roose‐Girma, Zora Modrušan, Rohit Reja, Meredith Sagolla, Joshua D. Webster, Vicky Cho, T. Daniel Andrews, Lucy X. Morris, Lisa A. Miosge, Christopher C. Goodnow, Edward M. Bertram, Vishva M. Dixit - Nature 2021 被引用: 849
- Cryopyrin activates the inflammasome in response to toxins and ATP
著者: Sanjeev Mariathasan, David S. Weiss, Kim Newton, Jacqueline McBride, Karen O’Rourke, Meron Roose-Girma, Wyne P. Lee, Yvette Weinrauch, Denise M. Monack, Vishva M. Dixit - Nature 2006 被引用: 3,076
- De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
著者: Ingrid E. Wertz, Karen O’Rourke, Honglin Zhou, Michael Eby, L. Aravind, Somasekar Seshagiri, Ping Wu, Christian Wiesmann, Rohan T. Baker, David L. Boone, Averil Ma, Eugene V. Koonin, Vishva M. Dixit - Nature 2004 被引用: 1,843
- FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex
著者: Marta Muzio, Arul M. Chinnaiyan, Frank Kischkel, Karen O’Rourke, Andrej Shevchenko, Jian Ni, Carsten Scaffidi, James D. Bretz, Mei Zhang, Reiner Gentz, Matthias Mann, Peter H. Krammer, Marcus E. Peter, Vishva M. Dixit - Cell 1996 被引用: 3,067
- IRF2 transcriptionally induces GSDMD expression for pyroptosis
著者: Nobuhiko Kayagaki, Bettina L. Lee, Irma B. Stowe, Opher S. Kornfeld, Karen O’Rourke, Kathleen M. Mirrashidi, Benjamin Haley, Colin Watanabe, Merone Roose‐Girma, Zora Modrušan, Sarah Kummerfeld, Rohit Reja, Yafei Zhang, Vicky Cho, T. Daniel Andrews, Lucy X. Morris, Christopher C. Goodnow, Edward M. Bertram, Vishva M. Dixit - Science Signaling 2019 被引用: 185
- Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
著者: Ingrid E. Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Daniel J. Anderson, Elizabeth Helgason, James A. Ernst, Mike Eby, Jinfeng Liu, Lisa D. Belmont, Joshua S. Kaminker, Karen O’Rourke, Kanan Pujara, Pawan Bir Kohli, Adam R. Johnson, Mark L. Chiu, Jennie R. Lill, Peter K. Jackson, Wayne J. Fairbrother, Somasekar Seshagiri, Mary J. C. Ludlam, Kevin G. Leong, Erin C. Dueber, Heather Maecker, David C.S. Huang, Vishva M. Dixit - Nature 2011 被引用: 820
- Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
著者: Muneesh Tewari, Long T. Quan, Karen O’Rourke, Serge Desnoyers, Zhi Jiang Zeng, David R Beidler, Guy G. Poirier, Guy S. Salvesen, Vishva M. Dixit - Cell 1995 被引用: 2,393
- FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis
著者: Arul M. Chinnaiyan, Karen O’Rourke, Muneesh Tewari, Vishva M. Dixit - Cell 1995 被引用: 2,427
- The Receptor for the Cytotoxic Ligand TRAIL
著者: Guohua Pan, Karen O’Rourke, Arul M. Chinnaiyan, Reiner Gentz, Reinhard Ebner, Jian Ni, Vishva M. Dixit - Science 1997 被引用: 1,778
- A Deubiquitinase That Regulates Type I Interferon Production
著者: Nobuhiko Kayagaki, Qui Phung, Salina Chan, Ruchir Chaudhari, Casey Quan, Karen O’Rourke, Michael Eby, Eric M. Pietras, Genhong Cheng, J. Fernando Bazán, Zemin Zhang, David Arnott, Vishva M. Dixit - Science 2007 被引用: 454
- Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
著者: Martin Schwickart, Xiaodong Huang, Jennie R. Lill, Jinfeng Liu, Ronald E. Ferrando, Dorothy French, Heather Maecker, Karen O’Rourke, Fernando Bazán, Jeffrey Eastham‐Anderson, Yue Peng, David Dornan, David C.S. Huang, Vishva M. Dixit - Nature 2009 被引用: 622
- Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
著者: Jonathan Jones, Nobuhiko Kayagaki, Petr Brož, Thomas Henry, Kim Newton, Karen O’Rourke, Salina Chan, Jennifer J. Dong, Yan Qu, Meron Roose-Girma, Vishva M. Dixit, Denise M. Monack - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 被引用: 477
- Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95
著者: Arul M. Chinnaiyan, Karen O’Rourke, Guo-Liang Yu, Robert H. Lyons, Manish Garg, Delin Duan, Lily Xing, Reiner Gentz, Jian Ni, Vishva M. Dixit - Science 1996 被引用: 654
- Human De-Etiolated-1 Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase
著者: Ingrid E. Wertz, Karen O’Rourke, Zemin Zhang, David Dornan, David Arnott, Raymond J. Deshaies, Vishva M. Dixit - Science 2004 被引用: 370
- Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1
著者: Shahram Misaghi, Søren Ottosen, Anita Izrael-Tomasevic, David Arnott, Mohamed Lamkanfi, James Lee, Jinfeng Liu, Karen O’Rourke, Vishva M. Dixit, Angus C. Wilson - Molecular and Cellular Biology 2009 被引用: 216
- Bcl10 activates the NF-κB pathway through ubiquitination of NEMO
著者: Honglin Zhou, Ingrid E. Wertz, Karen O’Rourke, Mark Ultsch, Somasekar Seshagiri, Michael Eby, Wei Xiao, Vishva M. Dixit - Nature 2003 被引用: 526
- COP1 is a tumour suppressor that causes degradation of ETS transcription factors
著者: Alberto C. Vitari, Kevin G. Leong, Kim Newton, Cindy J. Yee, Karen O’Rourke, Jinfeng Liu, Lilian Phu, Rajesh Vij, Ronald E. Ferrando, Suzana S. Couto, Sankar Mohan, Ajay Pandita, Jo-Anne Hongo, David Arnott, Ingrid E. Wertz, Wei‐Qiang Gao, Dorothy French, Vishva M. Dixit - Nature 2011 被引用: 171
- Caspase-9, Bcl-XL, and Apaf-1 Form a Ternary Complex
著者: Guohua Pan, Karen O’Rourke, Vishva M. Dixit - Journal of Biological Chemistry 1998 被引用: 522
- FADD/MORT1 Is a Common Mediator of CD95 (Fas/APO-1) and Tumor Necrosis Factor Receptor-induced Apoptosis
著者: Arul M. Chinnaiyan, Clifford G. Tepper, Michael F. Seldin, Karen O’Rourke, Frank Kischkel, Stefan Hellbardt, Peter H. Krammer, Marcus E. Peter, Vishva M. Dixit - Journal of Biological Chemistry 1996 被引用: 774
- Interaction of CED-4 with CED-3 and CED-9: A Molecular Framework for Cell Death
著者: Arul M. Chinnaiyan, Karen O’Rourke, Brian R. Lane, Vishva M. Dixit - Science 1997 被引用: 638
- Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin.
著者: Vishva M. Dixit, S Green, Vidya Sarma, Lawrence B. Holzman, F.W. Wolf, Karen O’Rourke, Peter A. Ward, Edward V. Prochownik, R M Marks - Journal of Biological Chemistry 1990 被引用: 376
- Identification of Paracaspases and Metacaspases
著者: Anthony G. Uren, Karen O’Rourke, L. Aravind, M. Teresa Pisabarro, Somasekar Seshagiri, Eugene V. Koonin, Vishva M. Dixit - Molecular Cell 2000 被引用: 238
- The PYRIN domain: A member of the death domain‐fold superfamily
著者: Wayne J. Fairbrother, Nathaniel C. Gordon, Eric W. Humke, Karen O’Rourke, Melissa A. Starovasnik, Jianping Yin, Vishva M. Dixit - Protein Science 2001 被引用: 153
