Koen Andries
1978–2024 年に発表
- 76
- 論文数
- 18,180
- 被引用数
- 70
- h 指数
- 75
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine68.3%
- Biochemistry, Genetics and Molecular Biology14.1%
- Immunology and Microbiology5.2%
- Chemistry4.2%
- Computer Science3.6%
- Pharmacology, Toxicology and Pharmaceutics1.5%
- その他3.1%
トピック
- Tuberculosis Research and Epidemiology16%
- Mycobacterium research and diagnosis7.3%
- HIV/AIDS drug development and treatment5.8%
- HIV Research and Treatment4.9%
- Cancer therapeutics and mechanisms4.6%
- Pneumocystis jirovecii pneumonia detection and treatment3.3%
- その他58.1%
共著者
- Paul A. J. Janssen16
- Rudi Pauwels16
- Jérôme Guillemont14
- Nacer Lounis14
- Anil Koul12
- Eddy Arnold12
- Kalyan Das10
- Marie‐Pierre de Béthune9
- Dirk Bald8
- Michael J. Kukla8
- Eric L. Nuermberger7
- Jan Heeres7
- Marc R. de Jonge7
- Donald Ludovici6
- Lucien M. H. Koymans6
- Rudy Willebrords6
- Stephen H. Hughes6
- Hilde Azijn5
- Holger Lill5
- Luc Vranckx5
- Paul Lewi5
- Tom Gevers5
- Vincent Jarlier5
- Alexander S. Pym4
全論文
- A Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis
著者: Koen Andries, Peter Verhasselt, Jérôme Guillemont, Hinrich W. H. Göhlmann, Jean‐Marc Neefs, Hans Christian Winkler, Jef Van Gestel, Philip Timmerman, Min Zhu, Ennis Lee, Peter Williams, Didier de Chaffoy, Emma Huitric, Sven Hoffner, Emmanuelle Cambau, C. Truffot-Pernot, Nacer Lounis, Vincent Jarlier - Science 2004 被引用: 2,169
- Multidrug-Resistant Tuberculosis and Culture Conversion with Bedaquiline
著者: Andreas H. Diacon, Alexander S. Pym, Martin P. Grobusch, Jorge M. de los Rios, Eduardo Gotuzzo, I. А. Vаsilyevа, Vaira Leimane, Koen Andries, Nyasha Bakare, Tine De Marez, Myriam Haxaire-Theeuwes, Nacer Lounis, Paul Meyvisch, Els De Paepe, Rolf P. G. van Heeswijk, Brian Dannemann - New England Journal of Medicine 2014 被引用: 752
- Acquired Resistance of Mycobacterium tuberculosis to Bedaquiline
著者: Koen Andries, Cristina Villellas, Nele Coeck, Kim Thys, Tom Gevers, Luc Vranckx, Nacer Lounis, Bouke C. de Jong, Anil Koul - PLoS ONE 2014 被引用: 431
- Bedaquiline in the treatment of multidrug- and extensively drug-resistant tuberculosis
著者: Alexander S. Pym, Andreas H. Diacon, Shenjie Tang, Francesca Conradie, Manfred Danilovitš, Charoen Chuchottaworn, I. А. Vаsilyevа, Koen Andries, Nyasha Bakare, Tine De Marez, Myriam Haxaire-Theeuwes, Nacer Lounis, Paul Meyvisch, Ben Van Baelen, Rolf P. G. van Heeswijk, Brian Dannemann - European Respiratory Journal 2015 被引用: 341
- Towards a new combination therapy for tuberculosis with next generation benzothiazinones
著者: Vadim Makarov, Benoît Lechartier, Ming Zhang, João Neres, Astrid M. van der Sar, Susanne A. Raadsen, Ruben C. Hartkoorn, O. B. Ryabova, Anthony Vocat, Laurent A. Décosterd, Nicolas Widmer, Thierry Buclin, Wilbert Bitter, Koen Andries, Florence Pojer, Paul J. Dyson, Stewart T. Cole - EMBO Molecular Medicine 2014 被引用: 385
- The challenge of new drug discovery for tuberculosis
著者: Anil Koul, Éric Arnoult, Nacer Lounis, Jérôme Guillemont, Koen Andries - Nature 2011 被引用: 1,047
- The Diarylquinoline TMC207 for Multidrug-Resistant Tuberculosis
著者: Andreas H. Diacon, Alexander S. Pym, Martin P. Grobusch, R. F. Patientia, Roxana Rustomjee, Liesl Page‐Shipp, Christoffel Pistorius, René Krause, Mampedi Bogoshi, Gavin Churchyard, Amour Venter, Jenny Allen, Juan Carlos Palomino, Tine De Marez, Rolf P. G. van Heeswijk, Nacer Lounis, Paul Meyvisch, Johan Verbeeck, Wim Parys, K. De Beule, Koen Andries, David F. Mc Neeley - New England Journal of Medicine 2009 被引用: 839
- Diarylquinolines target subunit c of mycobacterial ATP synthase
著者: Anil Koul, Najoua Dendouga, Karen Vergauwen, Brenda Molenberghs, Luc Vranckx, Rudy Willebrords, Zorica Stanojević-Ristić, Holger Lill, Ismet Dorange, Jérôme Guillemont, Dirk Bald, Koen Andries - Nature Chemical Biology 2007 被引用: 548
- Mutations in pepQ Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis
著者: Deepak V. Almeida, Thomas R. Ioerger, Sandeep Tyagi, Si-Yang Li, Khisimuzi Mdluli, Koen Andries, J Grosset, J.C. Sacchettini, Eric L. Nuermberger - Antimicrobial Agents and Chemotherapy 2016 被引用: 213
- Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism
著者: Anil Koul, Luc Vranckx, Neeraj Dhar, Hinrich W. H. Göhlmann, Emre Özdemir, Jean‐Marc Neefs, Melanie Schulz, Ping Lü, Ejvind Mørtz, John D. McKinney, Koen Andries, Dirk Bald - Nature Communications 2014 被引用: 293
- Bactericidal mode of action of bedaquiline
著者: Kiel Hards, Jennifer Robson, Michael Berney, Lisa E. Shaw, Dirk Bald, Anil Koul, Koen Andries, Gregory M. Cook - Journal of Antimicrobial Chemotherapy 2015 被引用: 232
- Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice
著者: Scott M. Irwin, Brendan Prideaux, Edward Lyon, Matthew Zimmerman, Elizabeth J. Brooks, Christopher Schrupp, Chao Chen, Matthew J. Reichlen, Bryce Asay, Martin I. Voskuil, Eric L. Nuermberger, Koen Andries, Michael A. Lyons, Véronique Dartois, Anne J. Lenaerts - ACS Infectious Diseases 2016 被引用: 155
- Rates and Mechanisms of Resistance Development inMycobacterium tuberculosisto a Novel Diarylquinoline ATP Synthase Inhibitor
著者: Emma Huitric, Peter Verhasselt, A. Koul, Koen Andries, Sven Hoffner, Dan I. Andersson - Antimicrobial Agents and Chemotherapy 2009 被引用: 216
- Diarylquinolines Are Bactericidal for Dormant Mycobacteria as a Result of Disturbed ATP Homeostasis
著者: Anil Koul, Luc Vranckx, Najoua Dendouga, Wendy Balemans, Ilse Van den Wyngaert, Karen Vergauwen, Hinrich W. H. Göhlmann, Rudy Willebrords, Alain Poncelet, Jérôme Guillemont, Dirk Bald, Koen Andries - Journal of Biological Chemistry 2008 被引用: 367
- Discovery and Development of SQ109: A New Antitubercular Drug with a Novel Mechanism of Action
著者: Katherine A. Sacksteder, Marina Protopopova, Clifton E. Barry, Koen Andries, Carol A. Nacy - Future Microbiology 2012 被引用: 275
- Unexpected high prevalence of resistance-associatedRv0678variants in MDR-TB patients without documented prior use of clofazimine or bedaquiline
著者: Cristina Villellas, Nele Coeck, Conor J. Meehan, Nacer Lounis, Bouke C. de Jong, Leen Rigouts, Koen Andries - Journal of Antimicrobial Chemotherapy 2016 被引用: 171
- Susceptibility of Mycobacterium abscessus to Antimycobacterial Drugs in Preclinical Models
著者: Andrés Obregón‐Henao, Kimberly Arnett, Marcela Henao‐Tamayo, Lisa M. Massoudi, Elizabeth Creissen, Koen Andries, Anne J. Lenaerts, Diane Ordway - Antimicrobial Agents and Chemotherapy 2015 被引用: 120
- Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants
著者: Kalyan Das, Arthur D. Clark, Paul Lewi, Jan Heeres, Marc R. de Jonge, Lucien M. H. Koymans, H. Maarten Vinkers, Frederik F. D. Daeyaert, Donald Ludovici, Michael J. Kukla, Bart De Corte, Robert W. Kavash, Chih Y. Ho, Ye Hong, Mark. A. Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre de Béthune, Paul L. Boyer, Patrick K. Clark, Stephen H. Hughes, Paul A. J. Janssen, Eddy Arnold - Journal of Medicinal Chemistry 2004 被引用: 511
- Location of Persisting Mycobacteria in a Guinea Pig Model of Tuberculosis Revealed by R207910
著者: Anne J. Lenaerts, Donald R. Hoff, Sahar Aly, Stefan Ehlers, Koen Andries, Luis Cantarero, Ian M. Orme, Randall J. Basaraba - Antimicrobial Agents and Chemotherapy 2007 被引用: 259
- The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress
著者: Ping Lü, Marieke H. Heineke, Anil Koul, Koen Andries, Gregory M. Cook, Holger Lill, Rob J. M. van Spanning, Dirk Bald - Scientific Reports 2015 被引用: 120
- 6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis
著者: Amy S.T. Tong, Peter J. Choi, Adrian Blaser, Hamish S. Sutherland, Sophia K. Y. Tsang, Jérôme Guillemont, Magali Motte, Christopher B. Cooper, Koen Andries, Walter Van den Broeck, Scott G. Franzblau, Anna M. Upton, William A. Denny, Brian D. Palmer, Daniel Conole - ACS Medicinal Chemistry Letters 2017 被引用: 83
- Randomized Pilot Trial of Eight Weeks of Bedaquiline (TMC207) Treatment for Multidrug-Resistant Tuberculosis: Long-Term Outcome, Tolerability, and Effect on Emergence of Drug Resistance
著者: Andreas H. Diacon, Peter R. Donald, Alexander S. Pym, Martin P. Grobusch, R. F. Patientia, Russel Mahanyele, Nonkqubela Bantubani, R. Narasimooloo, Tine De Marez, Rolf van Heeswijk, Nacer Lounis, Paul Meyvisch, Koen Andries, D. F. McNeeley - Antimicrobial Agents and Chemotherapy 2012 被引用: 380
- In Search of a Novel Anti-HIV Drug: Multidisciplinary Coordination in the Discovery of 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, Rilpivirine)
著者: Paul A. J. Janssen, Paul Lewi, Eddy Arnold, Frits Daeyaert, Marc R. de Jonge, Jan Heeres, Luc Koymans, Maarten Vinkers, Jérôme Guillemont, Élisabeth Pasquier, Mike Kukla, D.W. Ludovici, Koen Andries, Marie‐Pierre de Béthune, Rudi Pauwels, Kalyan Das, Art D. Clark, Yulia Volovik Frenkel, Stephen H. Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels - Journal of Medicinal Chemistry 2004 被引用: 342
- Sterilizing Activity of Novel TMC207- and PA-824-Containing Regimens in a Murine Model of Tuberculosis
著者: Rokeya Tasneen, Si-Yang Li, Charles A. Peloquin, Dinesh Taylor, Kathy N. Williams, Koen Andries, Khisimuzi Mdluli, Eric L. Nuermberger - Antimicrobial Agents and Chemotherapy 2011 被引用: 210
