Lee J. Helman
1977–2023 年に発表
- 105
- 論文数
- 20,221
- 被引用数
- 83
- h 指数
- 105
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine57%
- Biochemistry, Genetics and Molecular Biology32.9%
- Immunology and Microbiology6.4%
- Engineering1.1%
- Neuroscience0.7%
- Chemistry0.3%
- その他1.6%
トピック
- Sarcoma Diagnosis and Treatment6.8%
- CAR-T cell therapy research4.4%
- Immunotherapy and Immune Responses3.5%
- Cancer, Hypoxia, and Metabolism3.4%
- Epigenetics and DNA Methylation2.1%
- Immune Cell Function and Interaction2%
- その他77.8%
共著者
- Paul S. Meltzer20
- Chand Khanna18
- Arnulfo Mendoza12
- Choh Yeung11
- Seth M. Steinberg11
- Javed Khan9
- Maria Tsokos8
- Markku Miettinen8
- Xiaolin Wan8
- Brigitte C. Widemann7
- Derek LeRoith7
- James H. Doroshow7
- Shivaani Kummar7
- Su Young Kim7
- Crystal L. Mackall6
- Denise K. Reinke6
- Katherine A. Janeway6
- Lauren Long6
- Patrick J. Grohar6
- Robert J. Kinders6
- Anthony J. Murgo5
- Eva Dombi5
- Glenn Merlino5
- Jerry M. Collins5
全論文
- New Horizons in the Treatment of Osteosarcoma
著者: Paul S. Meltzer, Lee J. Helman - New England Journal of Medicine 2021 被引用: 651
- Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1
著者: Paul F. Robbins, Richard A. Morgan, Steven A. Feldman, James C. Yang, Richard M. Sherry, Mark E. Dudley, John R. Wunderlich, Azam Nahvi, Lee J. Helman, Crystal L. Mackall, Udai S. Kammula, Marybeth S. Hughes, Nicholas P. Restifo, Mark Raffeld, Chyi‐Chia Richard Lee, Catherine Lévy, Yong F. Li, Mona El‐Gamil, Susan Schwarz, Carolyn M. Laurençot, Steven A. Rosenberg - Journal of Clinical Oncology 2011 被引用: 1,610
- Molecular Subtypes ofKIT/PDGFRAWild-Type Gastrointestinal Stromal Tumors
著者: Sosipatros A. Boikos, Alberto S. Pappo, J. Keith Killian, Michael P. LaQuaglia, Chris B. Weldon, Suzanne George, Jonathan C. Trent, Margaret von Mehren, Jennifer Wright, J. D. Schiffman, Margarita Raygada, Karel Pacák, Paul S. Meltzer, Markku Miettinen, Constantine A. Stratakis, Katherine A. Janeway, Lee J. Helman - JAMA Oncology 2016 被引用: 407
- Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models
著者: James G. Taylor, Adam Cheuk, Patricia Tsang, Joon‐Yong Chung, Young Song, Krupa Desai, Yanlin Yu, Qingrong Chen, Kushal Shah, Victoria Youngblood, Jun Fang, Su Young Kim, Choh Yeung, Lee J. Helman, Arnulfo Mendoza, Vu N. Ngo, Louis M. Staudt, Jun S. Wei, Chand Khanna, Daniel Catchpoole, Stephen J. Qualman, Stephen M. Hewitt, Glenn Merlino, Stephen J. Chanock, Javed Khan - Journal of Clinical Investigation 2009 被引用: 322
- Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma
著者: Choh Yeung, Anna E. Gibson, Sameer H. Issaq, Nobu Oshima, Joshua T. Baumgart, Leah D. Edessa, Ganesha Rai, Daniel J. Urban, Michelle S. Johnson, Gloria A. Benavides, Giuseppe L. Squadrito, Marielle E. Yohe, Haiyan Lei, Sandy Eldridge, John Hamre, Tyrone Dowdy, Victor Ruiz‐Rodado, Adrian Lita, Arnulfo Mendoza, Jack F. Shern, Mioara Larion, Lee J. Helman, Gordon M. Stott, Murali C. Krishna, Matthew D. Hall, Victor Darley‐Usmar, Leonard Μ. Neckers, Christine M. Heske - Cancer Research 2019 被引用: 130
- Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor
著者: Jonathan Keith Killian, Su Young Kim, Markku Miettinen, Carly Smith, Maria J. Merino, Maria Tsokos, Martha Quezado, William I. Smith, Mona S. Jahromi, Paraskevi Xekouki, Eva Szarek, Robert L. Walker, Jerzy Lasota, Mark Raffeld, Brandy Klotzle, Zengfeng Wang, Laura Jones, Yuelin J. Zhu, Yonghong Wang, Joshua J. Waterfall, Maureen J. O’Sullivan, Marina Bibikova, Karel Pacák, Constantine A. Stratakis, Katherine A. Janeway, Joshua D. Schiffman, Jian-Bing Fan, Lee J. Helman, Paul S. Meltzer - Cancer Discovery 2013 被引用: 355
- Positively selected enhancer elements endow osteosarcoma cells with metastatic competence
著者: James J. Morrow, Ian Bayles, Alister P. W. Funnell, Tyler E. Miller, Alina Saiakhova, Michael M. Lizardo, Cynthia F. Bartels, Maaike Y. Kapteijn, Stevephen Hung, Arnulfo Mendoza, Gursimran Dhillon, Daniel R. Chee, Jay Myers, Frederick H. Allen, Marco Gambarotti, Alberto Righi, Analisa DiFeo, Brian P. Rubin, Alex Y. Huang, Paul S. Meltzer, Lee J. Helman, Piero Picci, Henri H. Versteeg, J Stamatoyannopoulos, Chand Khanna, Peter C. Scacheri - Nature Medicine 2018 被引用: 173
- Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations
著者: Katherine A. Janeway, Su Young Kim, Maya Lodish, Vânia Nosé, Pierre Rustin, José Gaal, Patricia L. M. Dahia, Bernadette Liegl, Evan Ball, Margarita Raygada, Angela H. Lai, Lorna Kelly, Jason L. Hornick, Maureen J. O’Sullivan, Ronald R. de Krijger, Winand N.M. Dinjens, George D. Demetri, Cristina R. Antonescu, Jonathan A. Fletcher, Lee J. Helman, Constantine A. Stratakis - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 被引用: 611
- Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis)
著者: Shivaani Kummar, Geraldine O’Sullivan Coyne, T. Khanh, Barış Türkbey, Paul S. Meltzer, Eric C. Polley, Peter L. Choyke, Robert Meehan, Rasa Vilimas, Yvonne Horneffer, Lamin Juwara, Ann Lih, Amul Choudhary, Sandra A. Mitchell, Lee J. Helman, James H. Doroshow, Alice P. Chen - Journal of Clinical Oncology 2017 被引用: 188
- The Childhood Cancer Data Initiative: Using the Power of Data to Learn From and Improve Outcomes for Every Child and Young Adult With Pediatric Cancer
著者: Joseph Flores‐Toro, Subhashini Jagu, Gregory T. Armstrong, David F. Arons, Gregory J. Aune, Stephen J. Chanock, Douglas S. Hawkins, Allison P. Heath, Lee J. Helman, Katherine A. Janeway, Jason Levine, Ellyn Miller, Lynne Penberthy, Charles W.M. Roberts, Eve Shalley, Jack F. Shern, Malcolm A. Smith, Louis M. Staudt, Samuel L. Volchenboum, Jinghui Zhang, Jean C. Zenklusen, Douglas R. Lowy, Norman E. Sharpless, Jaime M. Guidry Auvil, Anthony R. Kerlavage, Brigitte C. Widemann, Gregory H. Reaman, Warren A. Kibbe, James H. Doroshow, on behalf of Childhood Cancer Data Initiative Working Groups, Richard Aplenc, Caitlyn W. Barrett, Naomi Bartley, Vicki Buenger, Ethan Cerami, Susan L. Cohn, Susan I. Colace, Carrye Cost, Brian D. Crompton, Tanja M. Davidsen, Sharon J. Diskin, Jamie Ennis Bloyd, Suzanne J. Forrest, Maryam Fouladi, Amar Gajjar, Julia Glade Bender, Nancy Goodman, M. Monica Gramatges, Casey S. Greene, Julie Guillot, Amanda Haddock, Melissa Haendel, D. Ashley Hill, Amie E. Hwang, Daphne Kaas-Hogan, E. Anders Kolb, Andrew L. Kung, Salvatore La Rosa, Theodore W. Laetsch, Elizabeth R. Lawlor, Philip J. Lupo, Troy A. McEachron, Clay McLeod, Shannon K. McWeeney, Jill P. Mesirov, Sarah Milberg, Andy Olshan, Corrie Painter, Donald W. Parsons, Aubrey Reichard-Eline, Karlyne M. Reilly, Adam Resnick, Abby B. Sandler, Nita L. Seibel, Nilay D. Shah, David A. Siegel, Logan G. Spector, E. Alejandro Sweet‐Cordero, Gail E. Tomlinson, Emily S. Tonorezos, James V. Tricoli, Olena M. Vaske, Mary Frances Wedekind, Brent R. Weil, Torunn I. Yock - Journal of Clinical Oncology 2023 被引用: 47
- Mechanisms of sarcoma development
著者: Lee J. Helman, Paul S. Meltzer - Nature reviews. Cancer 2003 被引用: 451
- Presurgical Chemotherapy Compared With Immediate Surgery and Adjuvant Chemotherapy for Nonmetastatic Osteosarcoma: Pediatric Oncology Group Study POG-8651
著者: Allen M. Goorin, Douglas J. Schwartzentruber, Meenakshi Devidas, Mark C. Gebhardt, Alberto G. Ayala, Michael B. Harris, Lee J. Helman, Holcombe E. Grier, Michael P. Link - Journal of Clinical Oncology 2003 被引用: 395
- Surveillance Recommendations for Children with Overgrowth Syndromes and Predisposition to Wilms Tumors and Hepatoblastoma
著者: Jennifer M. Kalish, Leslie Doros, Lee J. Helman, Raoul C. M. Hennekam, Roland P. Kuiper, Saskia M. Maas, Eamonn R. Maher, Kim E. Nichols, Sharon E. Plon, Christopher C. Porter, Surya P. Rednam, Kris Ann P. Schultz, Lisa J. States, Gail E. Tomlinson, Kristin Zelley, Todd E. Druley - Clinical Cancer Research 2017 被引用: 201
- SARC025 arms 1 and 2: A phase 1 study of the poly(ADP‐ribose) polymerase inhibitor niraparib with temozolomide or irinotecan in patients with advanced Ewing sarcoma
著者: Rashmi Chugh, Karla V. Ballman, Lee J. Helman, Shreyaskumar Patel, Jeremy Whelan, Brigitte C. Widemann, Yao Lu, Douglas S. Hawkins, Leo Mascarenhas, John Glod, Jiuping Ji, Yiping Zhang, Denise Reinke, Sandra J. Strauss - Cancer 2020 被引用: 46
- R1507, a Monoclonal Antibody to the Insulin-Like Growth Factor 1 Receptor, in Patients With Recurrent or Refractory Ewing Sarcoma Family of Tumors: Results of a Phase II Sarcoma Alliance for Research Through Collaboration Study
著者: Alberto S. Pappo, Shreyaskumar Patel, John Crowley, Denise K. Reinke, Klaus-Peter Kuenkele, Sant P. Chawla, Guy C. Toner, Robert G. Maki, Paul A. Meyers, Rashmi Chugh, Kristen N. Ganjoo, Scott M. Schuetze, Heribert Juergens, Michael Leahy, Birgit Geoerger, Robert S. Benjamin, Lee J. Helman, Laurence H. Baker - Journal of Clinical Oncology 2011 被引用: 321
- Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism
著者: Xiaolin Wan, B Harkavy, N Shen, Patrick J. Grohar, Lee J. Helman - Oncogene 2006 被引用: 747
- Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening
著者: Patrick J. Grohar, Girma M. Woldemichael, Laurie B. Griffin, Arnulfo Mendoza, Qing-Rong Chen, Choh Yeung, Duane Currier, Sean Davis, Chand Khanna, Javed Khan, James B. McMahon, Lee J. Helman - JNCI Journal of the National Cancer Institute 2011 被引用: 204
- SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors
著者: Christine S. Higham, Seth M. Steinberg, Eva Dombi, Arie Perry, Lee J. Helman, Scott M. Schuetze, Joseph A. Ludwig, Arthur P. Staddon, Mohammed Milhem, Daniel A. Rushing, Robin L. Jones, Michael B. Livingston, Stewart Goldman, Christopher L. Moertel, Lars M. Wagner, David E. Janhofer, Christina M. Annunziata, Denise K. Reinke, Lauren Long, David Viskochil, Larry Baker, Brigitte C. Widemann - Sarcoma 2017 被引用: 97
- Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth
著者: Patrick J. Grohar, Laure E. Segars, Choh Yeung, Yves Pommier, Maurizio D’Incalci, Arnulfo Mendoza, Lee J. Helman - Clinical Cancer Research 2013 被引用: 86
- LRRC15 antibody‐drug conjugates show promise as osteosarcoma therapeutics in preclinical studies
著者: Katherine K. Slemmons, Sanjit Mukherjee, Paul S. Meltzer, James W. Purcell, Lee J. Helman - Pediatric Blood & Cancer 2020 被引用: 24
- A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma
著者: John A. Ligon, R. Taylor Sundby, Mary Frances Wedekind, Fernanda I. Arnaldez, Jaydira Del Rivero, Lori Wiener, Ramaprasad Srinivasan, Melissa Spencer, Amanda Carbonell, Haiyan Lei, John Shern, Seth M. Steinberg, William D. Figg, Cody J. Peer, Sara Zimmerman, Josquin Moraly, Xia Xu, Stephen Fox, King C. Chan, Michael I. Barbato, Þorkell Andrésson, Naomi Taylor, Karel Pacák, Jonathan Keith Killian, Eva Dombi, W. Marston Linehan, Markku Miettinen, Richard Piekarz, Lee J. Helman, Paul S. Meltzer, Brigitte C. Widemann, John Glod - Clinical Cancer Research 2022 被引用: 22
- Toward a Drug Development Path That Targets Metastatic Progression in Osteosarcoma
著者: Chand Khanna, Timothy M. Fan, Richard Görlick, Lee J. Helman, Eugenie S. Kleinerman, Peter C. Adamson, Peter J. Houghton, William D. Tap, Danny R. Welch, Patricia S. Steeg, Glenn Merlino, Poul H. Sorensen, Paul S. Meltzer, David G. Kirsch, Katherine A. Janeway, Brenda J. Weigel, Lor R. Randall, Stephen J. Withrow, Melissa Paoloni, Rosandra N. Kaplan, Beverly A. Teicher, Nita L. Seibel, Malcolm A. Smith, Aykut Üren, Shreyaskumar Patel, Jeffrey M. Trent, Sharon A. Savage, Lisa Mirabello, Denise K. Reinke, Donald A. Barkaukas, Mark Krailo, Mark L. Bernstein - Clinical Cancer Research 2014 被引用: 199
- Recurrent epimutation ofSDHCin gastrointestinal stromal tumors
著者: Jonathan Keith Killian, Markku Miettinen, Robert L. Walker, Yonghong Wang, Yuelin J. Zhu, Joshua J. Waterfall, Natalia Noyes, Parvathy Retnakumar, Zhiming Yang, William I. Smith, M. Scott Killian, Christopher Lau, Marbin Pineda, Jennifer Walling, Holly Stevenson, Carly Smith, Zengfeng Wang, Jerzy Lasota, Su Young Kim, Sosipatros A. Boikos, Lee J. Helman, Paul S. Meltzer - Science Translational Medicine 2014 被引用: 193
- A Pilot Study of Consolidative Immunotherapy in Patients with High-Risk Pediatric Sarcomas
著者: Crystal L. Mackall, Eunice H. Rhee, Elizabeth J. Read, Hanh Khuu, Susan F. Leitman, Donna Bernstein, Merertu Tesso, Lauren Long, David J. Grindler, Margret Merino, William Kopp, Maria Tsokos, Jay A. Berzofsky, Lee J. Helman - Clinical Cancer Research 2008 被引用: 158
