Leonard D. Shultz
1975–2024 年に発表
- 181
- 論文数
- 37,220
- 被引用数
- 108
- h 指数
- 180
- i10 指数
被引用数
引用元
国・地域
機関
- Harvard University1.2%
- Inserm0.8%
- Jackson Laboratory0.6%
- Howard Hughes Medical Institute0.6%
- Stanford University0.6%
- University of Pennsylvania0.6%
- その他95.6%
分野
- Medicine45.2%
- Biochemistry, Genetics and Molecular Biology31.7%
- Immunology and Microbiology17.6%
- Neuroscience2.4%
- Engineering1.1%
- Agricultural and Biological Sciences0.6%
- その他1.4%
トピック
- Immune Cell Function and Interaction4.7%
- T-cell and B-cell Immunology3.5%
- Immunotherapy and Immune Responses3.2%
- Immune cells in cancer2.6%
- Cancer Cells and Metastasis2.5%
- CAR-T cell therapy research2.2%
- その他81.3%
共著者
- Dale L. Greiner73
- Michael A. Brehm37
- Fumihiko Ishikawa18
- Lisa Burzenski13
- Yoriko Saito13
- Bruce Gott11
- Aldo A. Rossini9
- Osamu Ohara8
- Alvin C. Powers7
- Bonnie Lyons7
- Chunhua Dai7
- Edward H. Leiter7
- Jean Leif7
- Joseph Laning7
- Satoshi Tanaka7
- Shuichi Taniguchi7
- T. V. Rajan7
- Todd Pearson7
- Greg Poffenberger6
- Guangwen Ren6
- James Keck6
- Rita Bottino6
- Sherri W. Christianson6
- Shinsuke Takagi6
全論文
- Humanized mouse models for immuno-oncology research
著者: Jane Chuprin, Hannah Buettner, Mina O. Seedhom, Dale L. Greiner, James Keck, Fumihiko Ishikawa, Leonard D. Shultz, Michael A. Brehm - Nature Reviews Clinical Oncology 2023 被引用: 360
- Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis
著者: Peishan Li, Ming Lü, Jiayuan Shi, Zheng Gong, Li Hua, Qing Li, Bora Lim, Xiang H.-F. Zhang, Xiaowen Chen, Sheng Li, Leonard D. Shultz, Guangwen Ren - Nature Immunology 2020 被引用: 242
- Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
著者: Zheng Gong, Qing Li, Jiayuan Shi, Jian Wei, Peishan Li, Chih‐Hao Chang, Leonard D. Shultz, Guangwen Ren - Immunity 2022 被引用: 244
- Human Lymphoid and Myeloid Cell Development in NOD/LtSz- scid IL2R γ null Mice Engrafted with Mobilized Human Hemopoietic Stem Cells,
著者: Leonard D. Shultz, Bonnie Lyons, Lisa Burzenski, Bruce Gott, Xiaohua Chen, Stanley Chaleff, Malak Kotb, Stephen D. Gillies, Marie King, Julie Mangada, Dale L. Greiner, Rupert Handgretinger - The Journal of Immunology 2005 被引用: 1,715
- Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells
著者: Zheng Gong, Qing Li, Jiayuan Shi, Edison T. Liu, Leonard D. Shultz, Guangwen Ren - Cell Metabolism 2022 被引用: 121
- Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis
著者: Zheng Gong, Qing Li, Jiayuan Shi, Peishan Li, Li Hua, Leonard D. Shultz, Guangwen Ren - Science Immunology 2023 被引用: 118
- Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status
著者: Peishan Li, Ming Lü, Jiayuan Shi, Li Hua, Zheng Gong, Qing Li, Leonard D. Shultz, Guangwen Ren - Nature Communications 2020 被引用: 157
- Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain
著者: Devon S. Svoboda, M. Inmaculada Barrasa, Jian Shu, Rosalie Rietjens, Shupei Zhang, Maya Mitalipova, Peter Berube, Dongdong Fu, Leonard D. Shultz, George W. Bell, Rudolf Jaenisch - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 被引用: 222
- Humanized mice for immune system investigation: progress, promise and challenges
著者: Leonard D. Shultz, Michael A. Brehm, J. Víctor García, Dale L. Greiner - Nature reviews. Immunology 2012 被引用: 963
- Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
著者: Fumihiko Ishikawa, Shuro Yoshida, Yoriko Saito, Atsushi Hijikata, Hiroshi Kitamura, Satoshi Tanaka, Ryu Nakamura, Toru Tanaka, Hiroko Tomiyama, Noriyuki Saito, Mitsuhiro Fukata, Toshihiro Miyamoto, Bonnie Lyons, Koichi Ohshima, Naoyuki Uchida, Shuichi Taniguchi, Osamu Ohara, Koichi Akashi, Mine Harada, Leonard D. Shultz - Nature Biotechnology 2007 被引用: 975
- Humanized immune system mouse models: progress, challenges and opportunities
著者: Todd M. Allen, Michael A. Brehm, Sandra H. Bridges, S E Ferguson, Priti Kumar, Oleg Mirochnitchenko, Karolina Palucka, Roberta Pelanda, Brigitte E. Sanders-Beer, Leonard D. Shultz, Lishan Su, Mercy PrabhuDas - Nature Immunology 2019 被引用: 249
- Humanized mice in translational biomedical research
著者: Leonard D. Shultz, Fumihiko Ishikawa, Dale L. Greiner - Nature reviews. Immunology 2007 被引用: 1,259
- Humanized Mouse Models of Clinical Disease
著者: Nicole C. Walsh, Laurie L. Kenney, Sonal Jangalwe, Ken‐Edwin Aryee, Dale L. Greiner, Michael A. Brehm, Leonard D. Shultz - Annual Review of Pathology Mechanisms of Disease 2016 被引用: 555
- Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice
著者: Fumihiko Ishikawa, Masaki Yasukawa, Bonnie Lyons, Shuro Yoshida, Toshihiro Miyamoto, Goichi Yoshimoto, Takeshi Watanabe, Koichi Akashi, Leonard D. Shultz, Mine Harada - Blood 2005 被引用: 920
- Lack of acute xenogeneic graft‐ versus ‐host disease, but retention of T‐cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression
著者: Michael A. Brehm, Laurie L. Kenney, Michael V. Wiles, Benjamin E. Low, Roland Tisch, Lisa Burzenski, Christian Mueller, Dale L. Greiner, Leonard D. Shultz - The FASEB Journal 2018 被引用: 182
- Multiple defects in innate and adaptive immunologic function in NOD/LtSz- scid mice.
著者: Leonard D. Shultz, Peter A. Schweitzer, Sherri W. Christianson, Bruce Gott, Isabelle B. Schweitzer, Barbara J. Tennent, Sarah McKenna, L E Mobraaten, T. V. Rajan, Dale L. Greiner, E H Leiter - The Journal of Immunology 1995 被引用: 1,227
- Humanized mice in studying efficacy and mechanisms of PD‐1‐targeted cancer immunotherapy
著者: Minan Wang, Li‐Chin Yao, Mingshan Cheng, Danying Cai, Jan Martínek, Chong-xian Pan, Wei Shi, Ai‐Hong Ma, Ralph W. de Vere White, Susan Airhart, Edison T. Liu, Jacques Banchereau, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, Karolina Palucka, James Keck - The FASEB Journal 2017 被引用: 354
- Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex
著者: Michelle A. King, Laurence Covassin, Michael A. Brehm, Waldemar J. Racki, Todd Pearson, Jean Leif, Joseph Laning, William L. Fodor, Oded Foreman, Lisa Burzenski, Thomas H. Chase, Bruce Gott, Aldo A. Rossini, Rita Bortell, Leonard D. Shultz, Dale L. Greiner - Clinical & Experimental Immunology 2009 被引用: 376
- Genetic risk converges on regulatory networks mediating early type 2 diabetes
著者: John T. Walker, Diane C. Saunders, Vivek Rai, Hung‐Hsin Chen, Peter Orchard, Chunhua Dai, Yasminye D. Pettway, Alexander L. Hopkirk, Conrad Reihsmann, Yicheng Tao, Simin Fan, Shristi Shrestha, Arushi Varshney, Lauren E. Petty, J. J. Wright, Christa Ventresca, Samir Agarwala, Radhika Aramandla, Greg Poffenberger, Regina Jenkins, Shaojun Mei, Nathaniel Hart, Sharon Phillips, Hakmook Kang, Dale L. Greiner, Leonard D. Shultz, Rita Bottino, Jie Liu, Jennifer E. Below, Stephen C.J. Parker, Alvin C. Powers, Marcela Briššová - Nature 2023 被引用: 71
- Mesenchymal stem cells: From regeneration to cancer
著者: Peishan Li, Zheng Gong, Leonard D. Shultz, Guangwen Ren - Pharmacology & Therapeutics 2019 被引用: 142
- Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma
著者: Ramona Crescenzo, Francesco Abate, Elena Lasorsa, Fabrizio Tabbò, Marcello Gaudiano, Nicoletta Chiesa, Filomena Di Giacomo, Elisa Spaccarotella, Luigi Barbarossa, Elisabetta Ercole, Maria Chiara Todaro, Michela Boi, Andrea Acquaviva, Elisa Ficarra, Domenico Novero, Andrea Rinaldi, Thomas Tousseyn, Andreas Rosenwald, Lukas Kenner, Lorenzo Cerroni, Alexandar Tzankov, Maurilio Ponzoni, Marco Paulli, Dennis D. Weisenburger, Wing C. Chan, Javeed Iqbal, Miguel Á. Piris, Alberto Zamò, Carmela Ciardullo, Davide Rossi, Gianluca Gaïdano, Stefano Pileri, Enrico Tiacci, Brunangelo Falini, Leonard D. Shultz, Laurence Mévellec, Jorge Vialard, Roberto Piva, Francesco Bertoni, Raúl Rabadán, Giorgio Inghirami - Cancer Cell 2015 被引用: 442
- α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes
著者: Marcela Briššová, Rachana Haliyur, Diane C. Saunders, Shristi Shrestha, Chunhua Dai, David M. Blodgett, Rita Bottino, Martha Campbell‐Thompson, Radhika Aramandla, Gregory Poffenberger, J Lindner, Fong Cheng Pan, Matthias G. von Herrath, Dale L. Greiner, Leonard D. Shultz, May Sanyoura, Louis H. Philipson, Mark A. Atkinson, David M. Harlan, Shawn Levy, Nripesh Prasad, Roland Stein, Alvin C. Powers - Cell Reports 2018 被引用: 219
- Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells
著者: Yoriko Saito, Hiroshi Kitamura, Atsushi Hijikata, Mariko Tomizawa-Murasawa, Satoshi Tanaka, Shinsuke Takagi, Naoyuki Uchida, Nahoko Suzuki, Akiko Sone, Yuho Najima, Hidetoshi Ozawa, Atsushi Wake, Shuichi Taniguchi, Leonard D. Shultz, Osamu Ohara, Fumihiko Ishikawa - Science Translational Medicine 2010 被引用: 458
- Enhanced development of functional human NK cells in NOD‐ scid‐IL2rg null mice expressing human IL15
著者: Ken‐Edwin Aryee, Lisa Burzenski, Li‐Chin Yao, James Keck, Dale L. Greiner, Leonard D. Shultz, Michael A. Brehm - The FASEB Journal 2022 被引用: 53
