Lewis E. Kay
1989–2025 年に発表
- 別表記
- Lewis E Kay
- 249
- 論文数
- 52,546
- 被引用数
- 130
- h 指数
- 244
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology68.4%
- Medicine10.4%
- Chemistry6.2%
- Materials Science3.4%
- Immunology and Microbiology2.8%
- Physics and Astronomy2%
- その他6.8%
トピック
- Protein Structure and Dynamics12.3%
- Enzyme Structure and Function6.7%
- RNA and protein synthesis mechanisms6.1%
- RNA Research and Splicing4.5%
- Advanced NMR Techniques and Applications3.1%
- RNA modifications and cancer2.8%
- その他64.5%
共著者
- Julie D. Forman‐Kay43
- Ad Bax23
- D.R. Muhandiram20
- Vitali Tugarinov17
- Pramodh Vallurupalli15
- D. Flemming Hansen14
- Mitsuhiko Ikura14
- Enrico Rennella13
- Daiwen Yang11
- Nikolai R. Skrynnikov11
- Yuki Toyama11
- Dmitry M. Korzhnev10
- Kevin H. Gardner10
- Robert W. Harkness10
- Ashok Sekhar9
- Frederick W. Dahlquist9
- Guillaume Bouvignies9
- Neil A. Farrow9
- Remco Sprangers9
- Wing‐Yiu Choy9
- Dennis A. Torchia8
- Rina Rosenzweig8
- Tomasz L. Religa8
- Tony Pawson8
全論文
- Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
著者: Jacob P. Brady, Patrick Farber, Ashok Sekhar, Yi‐Hsuan Lin, Rui Huang, Alaji Bah, Timothy J. Nott, Hue Sun Chan, Andrew J. Baldwin, Julie D. Forman‐Kay, Lewis E. Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 被引用: 587
- Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation
著者: Tae Hun Kim, Brian Tsang, Robert M. Vernon, Nahum Sonenberg, Lewis E. Kay, Julie D. Forman‐Kay - Science 2019 被引用: 377
- NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
著者: T. Reid Alderson, Lewis E. Kay - Cell 2021 被引用: 237
- Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch
著者: Alaji Bah, Robert M. Vernon, Zeba Rahman Siddiqui, Mickaël Krzeminski, Ranjith Muhandiram, Charlie W. Zhao, Nahum Sonenberg, Lewis E. Kay, Julie D. Forman‐Kay - Nature 2014 被引用: 570
- Studying “Invisible” Excited Protein States in Slow Exchange with a Major State Conformation
著者: Pramodh Vallurupalli, Guillaume Bouvignies, Lewis E. Kay - Journal of the American Chemical Society 2012 被引用: 540
- Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation
著者: Neil A. Farrow, Ranjith Muhandiram, Alex U. Singer, Steven M. Pascal, Cyril M. Kay, G Gish, Steven E. Shoelson, Tony Pawson, Julie D. Forman‐Kay, Lewis E. Kay - Biochemistry 1994 被引用: 2,111
- An NMR View of Protein Dynamics in Health and Disease
著者: Ashok Sekhar, Lewis E. Kay - Annual Review of Biophysics 2019 被引用: 180
- Intrinsic dynamics of an enzyme underlies catalysis
著者: Elan Eisenmesser, Óscar Millet, Wladimir Labeikovsky, Dmitry M. Korzhnev, Magnus Wolf‐Watz, Daryl A. Bosco, Jack J. Skalicky, Lewis E. Kay, Dorothee Kern - Nature 2005 被引用: 1,118
- Cross-Correlated Relaxation Enhanced 1H−13C NMR Spectroscopy of Methyl Groups in Very High Molecular Weight Proteins and Protein Complexes
著者: Vitali Tugarinov, Peter M. Hwang, Jason E. Ollerenshaw, Lewis E. Kay - Journal of the American Chemical Society 2003 被引用: 653
- Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase
著者: Tae Hun Kim, Brandon J. Payliss, Michael L. Nosella, Ian T. W. Lee, Yuki Toyama, Julie D. Forman‐Kay, Lewis E. Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 被引用: 116
- Structure of an Intermediate State in Protein Folding and Aggregation
著者: Philipp Neudecker, Paul Robustelli, Andrea Cavalli, P.J. Walsh, Patrik Lundström, Arash Zarrine‐Afsar, Simon Sharpe, Michele Vendruscolo, Lewis E. Kay - Science 2012 被引用: 406
- Poly(ADP-ribosyl)ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates
著者: Michael L. Nosella, Tae Hun Kim, Shuya Kate Huang, Robert W. Harkness, Monica M. Goncalves, Alisia Pan, Maria Tereshchenko, Siavash Vahidi, John L. Rubinstein, Hyun O. Lee, Julie D. Forman‐Kay, Lewis E. Kay - Molecular Cell 2024 被引用: 44
- Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
著者: Satra Nim, Darren M. O’Hara, Carles Corbi‐Verge, Albert Perez‐Riba, Kazuko Fujisawa, Minesh Kapadia, Hien Chau, Federica Albanese, Grishma Pawar, Mitchell L. de Snoo, Sophie G. Ngana, Ji‐Sun Kim, Omar M. A. El‐Agnaf, Enrico Rennella, Lewis E. Kay, Suneil K. Kalia, Lorraine V. Kalia, Philip M. Kim - Nature Communications 2023 被引用: 48
- Backbone dynamics of proteins as studied by nitrogen-15 inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease
著者: Lewis E. Kay, Dennis A. Torchia, Ad Bax - Biochemistry 1989 被引用: 1,792
- Design of amyloidogenic peptide traps
著者: Danny D. Sahtoe, Ewa A. Andrzejewska, Hannah L. Han, Enrico Rennella, Matthias M. Schneider, Georg Meisl, Maggie Ahlrichs, Justin Decarreau, Hannah Nguyen, Alex Kang, Paul M. Levine, Mila Lamb, Xinting Li, Asim K. Bera, Lewis E. Kay, Tuomas P. J. Knowles, David Baker - Nature Chemical Biology 2024 被引用: 39
- Isotope labeling strategies for the study of high-molecular-weight proteins by solution NMR spectroscopy
著者: Vitali Tugarinov, Voula Kanelis, Lewis E. Kay - Nature Protocols 2006 被引用: 540
- Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor
著者: Tanja Mittag, Stephen Orlicky, Wing‐Yiu Choy, Xiaojing Tang, Hong Lin, Frank Sicheri, Lewis E. Kay, Mike Tyers, Julie D. Forman‐Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 被引用: 343
- An Improved 15N Relaxation Dispersion Experiment for the Measurement of Millisecond Time-Scale Dynamics in Proteins
著者: D. Flemming Hansen, Pramodh Vallurupalli, Lewis E. Kay - The Journal of Physical Chemistry B 2007 被引用: 239
- Mapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory
著者: Yuki Toyama, Atul Rangadurai, Julie D. Forman‐Kay, Lewis E. Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 被引用: 60
- Correlating histone acetylation with nucleosome core particle dynamics and function
著者: Tae Hun Kim, Michael L. Nosella, Nicolas Bolik-Coulon, Robert W. Harkness, Shuya Kate Huang, Lewis E. Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 被引用: 41
- Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer
著者: Pramodh Vallurupalli, Ashok Sekhar, Tairan Yuwen, Lewis E. Kay - Journal of Biomolecular NMR 2017 被引用: 163
- A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery
著者: Zev A. Ripstein, Siavash Vahidi, Walid A. Houry, John L. Rubinstein, Lewis E. Kay - eLife 2020 被引用: 125
- New Tools Provide New Insights in NMR Studies of Protein Dynamics
著者: Anthony Mittermaier, Lewis E. Kay - Science 2006 被引用: 790
- NMR spectroscopy brings invisible protein states into focus
著者: Andrew J. Baldwin, Lewis E. Kay - Nature Chemical Biology 2009 被引用: 430
