Luke O'neill
1990–2025 年に発表
- 別表記
- Luke O’Neill · Luke O'Neill
- 269
- 論文数
- 93,965
- 被引用数
- 143
- h 指数
- 265
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology32.2%
- Medicine27.8%
- Immunology and Microbiology26.8%
- Neuroscience6.9%
- Agricultural and Biological Sciences1.6%
- Nursing1.4%
- その他3.3%
トピック
- Immune Response and Inflammation5.4%
- Inflammasome and immune disorders4.5%
- Immune cells in cancer4.3%
- Immune Cell Function and Interaction2.6%
- Neuroinflammation and Neurodegeneration Mechanisms2.3%
- interferon and immune responses2.1%
- その他78.8%
共著者
- Eva M. Pålsson‐McDermott27
- Anne F. McGettrick21
- Dylan G. Ryan16
- Kingston H. G. Mills15
- Andrew Bowie14
- Zbigniew Zasłona12
- Avril A. B. Robertson11
- Caroline A. Jefferies11
- Matthew A. Cooper11
- Rebecca C. Coll11
- Aisling Dunne10
- Alexander Hooftman10
- Katherine A. Fitzgerald10
- Sarah Doyle10
- Alessia Zotta9
- Annie M. Curtis9
- Leo A. B. Joosten9
- Michael P. Murphy9
- Mihai G. Netea9
- Moritz Haneklaus9
- Christian Frezza8
- Eicke Latz8
- Elizabeth Brint8
- Emily A. Day8
全論文
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
著者: Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik, Eva M. Pålsson‐McDermott, Anne F. McGettrick, Gautam Goel, Christian Frezza, Nicholas J. Bernard, Beth Kelly, Niamh H. Foley, Liang Zheng, Agnès Gardet, Zhen Tong, S. S. Jany, Sinéad C. Corr, Moritz Haneklaus, Brian E. Caffrey, Kerry A. Pierce, Sarah R. Walmsley, Federico C. Beasley, Eoin P. Cummins, Victor Nizet, Moira K. B. Whyte, Cormac T. Taylor, Hening Lin, Seth L. Masters, Eyal Gottlieb, Vincent P. Kelly, Clary B. Clish, Philip E. Auron, Ramnik J. Xavier, Luke O'neill - Nature 2013 被引用: 4,111
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
著者: Evanna L. Mills, Beth Kelly, Angela Logan, Ana S.H. Costa, Mukund Varma, Clare Bryant, Panagiotis Tourlomousis, J. Henry M. Däbritz, Eyal Gottlieb, Isabel Latorre, Sinéad C. Corr, Gavin McManus, Dylan G. Ryan, Howard T. Jacobs, Marten Szibor, Ramnik J. Xavier, Thomas Braun, Christian Frezza, Michael P. Murphy, Luke O'neill - Cell 2016 被引用: 2,258
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
著者: Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae, Sarah Higgins, Raúl Muñoz-Planillo, Marco Inserra, Irina Vetter, Lara S. Dungan, Brian G. Monks, Andrea Stutz, Daniel E. Croker, Mark S. Butler, Moritz Haneklaus, Caroline E. Sutton, Gabriel Núñez, Eicke Latz, Daniel L. Kastner, Kingston H. G. Mills, Seth L. Masters, Kate Schroder, Matthew A. Cooper, Luke O'neill - Nature Medicine 2015 被引用: 2,784
- A guide to immunometabolism for immunologists
著者: Luke O'neill, Rigel J. Kishton, Jeff Rathmell - Nature reviews. Immunology 2016 被引用: 3,072
- Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
著者: Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zasłona, Mark P. Jedrychowski, Ana S.H. Costa, Maureen Higgins, Emily Hams, John Szpyt, Marah C. Runtsch, Martin King, Joanna F. McGouran, Román Fischer, Benedikt M. Kessler, Anne F. McGettrick, Mark Hughes, Richard G. Carroll, Lee M. Booty, Elena V. Knatko, Paul J. Meakin, Michael L.J. Ashford, Louise K. Modis, Gino Brunori, Daniel C. Sévin, Padraic G. Fallon, Stuart T. Caldwell, Edmund R.S. Kunji, Edward T. Chouchani, Christian Frezza, Albena T. Dinkova‐Kostova, Richard C. Hartley, Michael P. Murphy, Luke O'neill - Nature 2018 被引用: 1,905
- mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
著者: Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer, Kelly M. Shepardson, Sadia Saeed, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis, Joost H.A. Martens, Nagesha Rao, Ali Aghajanirefah, Ganesh R. Manjeri, Li Yang, Daniela C. Ifrim, Rob J.W. Arts, Brian M. J. W. van der Veer, Peter M.T. Deen, Colin Logie, Luke O'neill, Peter H.G.M. Willems, Frank L. van de Veerdonk, J.W.M. van der Meer, Aylwin Ng, Leo A. B. Joosten, Cisca Wijmenga, Hendrik G. Stunnenberg, Ramnik J. Xavier, Mihai G. Netea - Science 2014 被引用: 2,224
- Trained immunity: A program of innate immune memory in health and disease
著者: Mihai G. Netea, Leo A. B. Joosten, Eicke Latz, Kingston H. G. Mills, Gioacchino Natoli, Hendrik G. Stunnenberg, Luke O'neill, Ramnik J. Xavier - Science 2016 被引用: 2,770
- Metabolic reprogramming in macrophages and dendritic cells in innate immunity
著者: Beth Kelly, Luke O'neill - Cell Research 2015 被引用: 1,811
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
著者: Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel, Mario Lauterbach, Frederick J. Sheedy, Laura E. Gleeson, Mirjam W.M. van den Bosch, Susan R. Quinn, Raquel Domingo-Fernandéz, Daniel Johnston, Jian‐kang Jiang, William J. Israelsen, Joseph Keane, Craig J. Thomas, Clary B. Clish, Matthew G. Vander Heiden, Ramnik J. Xavier, Luke O'neill - Cell Metabolism 2015 被引用: 1,375
- Macrophage Immunometabolism: Where Are We (Going)?
著者: Jan Van den Bossche, Luke O'neill, Deepthi Menon - Trends in Immunology 2017 被引用: 1,137
- Immunometabolism governs dendritic cell and macrophage function
著者: Luke O'neill, Edward J. Pearce - The Journal of Experimental Medicine 2015 被引用: 1,641
- The Role of HIF in Immunity and Inflammation
著者: Anne F. McGettrick, Luke O'neill - Cell Metabolism 2020 被引用: 750
- Mitochondria are the powerhouses of immunity
著者: Evanna L. Mills, Beth Kelly, Luke O'neill - Nature Immunology 2017 被引用: 1,150
- The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
著者: Alexander Hooftman, Stefano Angiari, Svenja Hester, Sarah E. Corcoran, Marah C. Runtsch, Chris Ling, Melanie C. Ruzek, Peter F. Slivka, Anne F. McGettrick, Kathy Banahan, Mark Hughes, Alan D. Irvine, Román Fischer, Luke O'neill - Cell Metabolism 2020 被引用: 588
- Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
著者: Richard D. Gordon, Eduardo A. Albornoz, Daniel C. Christie, Monica R. Langley, Vinod Kumar, Susanna Mantovani, Avril A. B. Robertson, Mark S. Butler, Dominic B. Rowe, Luke O'neill, Anumantha G. Kanthasamy, Kate Schroder, Matthew A. Cooper, Trent M. Woodruff - Science Translational Medicine 2018 被引用: 890
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
著者: Rob J.W. Arts, Boris Novakovic, Rob ter Horst, Agostinho Carvalho, Siroon Bekkering, Ekta Lachmandas, Fernando Rodrigues, Ricardo Silvestre, Shih‐Chin Cheng, Shuang-Yin Wang, Ehsan Habibi, Luís G. Gonçalves, Inês Mesquita, Cristina Cunha, Arjan van Laarhoven, Frank L. van de Veerdonk, David L. Williams, J.W.M. van der Meer, Colin Logie, Luke O'neill, Charles A. Dinarello, Niels P. Riksen, Reinout van Crevel, Clary B. Clish, Richard A. Notebaart, Leo A. B. Joosten, Hendrik G. Stunnenberg, Ramnik J. Xavier, Mihai G. Netea - Cell Metabolism 2016 被引用: 858
- Itaconate: the poster child of metabolic reprogramming in macrophage function
著者: Luke O'neill, Maxim N. Artyomov - Nature reviews. Immunology 2019 被引用: 625
- HIF1α and metabolic reprogramming in inflammation
著者: Sarah E. Corcoran, Luke O'neill - Journal of Clinical Investigation 2016 被引用: 738
- Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
著者: Marah C. Runtsch, Stefano Angiari, Alexander Hooftman, Ridhima Wadhwa, Yanling Zhang, Yunan Zheng, Joseph S. Spina, Melanie C. Ruzek, M.A. Argiriadi, Anne F. McGettrick, Rui Santalla Méndez, Alessia Zotta, Christian G. Peace, Aoife Walsh, Roberta Chirillo, Emily Hams, Padraic G. Fallon, Ranjith Jayaraman, Kamal Dua, Alexandra C. Brown, Richard Kim, Jay C. Horvat, Philip M. Hansbro, Chu Wang, Luke O'neill - Cell Metabolism 2022 被引用: 318
- Trained immunity, tolerance, priming and differentiation: distinct immunological processes
著者: Maziar Divangahi, Peter Aaby, Shabaana A. Khader, Luis B. Barreiro, Siroon Bekkering, Triantafyllos Chavakis, Reinout van Crevel, Nigel Curtis, Andrew R. DiNardo, Jorge Domínguez‐Andrés, Raphaël Duivenvoorden, Stephanie Fanucchi, Zahi A. Fayad, Elaine Fuchs, Mélanie Hamon, Kate L. Jeffrey, Nargis Khan, Leo A. B. Joosten, Eva Kaufmann, Eicke Latz, Giuseppe Matarese, J.W.M. van der Meer, Musa M. Mhlanga, Simone J.C.F.M. Moorlag, Willem J. M. Mulder, Shruti Naik, Boris Novakovic, Luke O'neill, Jordi Ochando, Keiko Ozato, Niels P. Riksen, Robert W. Sauerwein, Edward R. Sherwood, Andreas Schlitzer, Joachim L. Schultze, Michael H. Sieweke, Christine Stabell Benn, Henk G. Stunnenberg, Joseph C. Sun, Frank L. van de Veerdonk, Sebastian Weis, David L. Williams, Ramnik J. Xavier, Mihai G. Netea - Nature Immunology 2020 被引用: 595
- A guiding map for inflammation
著者: Mihai G. Netea, Frances R. Balkwill, Michel Chonchol, Fabio Cominelli, Marc Y. Donath, Evangelos J. Giamarellos‐Bourboulis, Douglas T. Golenbock, Mark S. Gresnigt, Michael T. Heneka, Hal M. Hoffman, Richard S. Hotchkiss, Leo A. B. Joosten, Daniel L. Kastner, Martin Körte, Eicke Latz, Peter Libby, Thomas Mandrup‐Poulsen, Alberto Mantovani, Kingston H. G. Mills, Kristen L. Nowak, Luke O'neill, Peter Pickkers, Tom van der Poll, Paul M. Ridker, Joost Schalkwijk, David A. Schwartz, Britta Siegmund, Clifford J. Steer, Herbert Tilg, Jos W.M. van der Meer, Frank L. van de Veerdonk, Charles A. Dinarello - Nature Immunology 2017 被引用: 823
- Krebs Cycle Reborn in Macrophage Immunometabolism
著者: Dylan G. Ryan, Luke O'neill - Annual Review of Immunology 2020 被引用: 427
- Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
著者: Alexander Hooftman, Christian G. Peace, Dylan G. Ryan, Emily A. Day, Ming Yang, Anne F. McGettrick, Maureen Yin, Erica N. Montano, Lihong Huo, Juliana E. Toller-Kawahisa, Vincent Zecchini, Tristram A.J. Ryan, Alfonso Bolado‐Carrancio, Alva M. Casey, Hiran A. Prag, Ana S.H. Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J. Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alex von Kriegsheim, Michael P. Murphy, Caroline A. Jefferies, Christian Frezza, Luke O'neill - Nature 2023 被引用: 224
- Targeting immunometabolism as an anti-inflammatory strategy
著者: Eva M. Pålsson‐McDermott, Luke O'neill - Cell Research 2020 被引用: 564
