Michael S. Wolfe
1987–2025 年に発表
- 107
- 論文数
- 25,283
- 被引用数
- 77
- h 指数
- 104
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine60.9%
- Biochemistry, Genetics and Molecular Biology26.1%
- Neuroscience6.3%
- Immunology and Microbiology2%
- Computer Science1.1%
- Chemistry0.8%
- その他2.8%
トピック
- Alzheimer's disease research and treatments18.5%
- Cholinesterase and Neurodegenerative Diseases5.4%
- Computational Drug Discovery Methods4.9%
- Neuroscience and Neuropharmacology Research2.6%
- Neuroinflammation and Neurodegeneration Mechanisms2.5%
- Developmental Biology and Gene Regulation2.4%
- その他63.7%
共著者
- Dennis J. Selkoe31
- W. Taylor Kimberly14
- Wenjuan Ye13
- Beth L. Ostaszewski12
- Weiming Xia10
- Thekla S. Diehl9
- Matthew J. LaVoie7
- Patrick C. Fraering7
- Sujan Devkota7
- Chad L. Moore6
- Oksana Berezovska6
- Yinglong Miao6
- Bart De Strooper5
- Masato Maesako5
- Raphael Kopan5
- William P. Esler5
- Alison Goate4
- Anna Y. Kornilova4
- Bradley T. Hyman4
- Daniel R. Montagna4
- Eric H. Schroeter4
- Lei Liu4
- Sanjay Bhattarai4
- Talat Rahmati4
全論文
- Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
著者: Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva, William K. Cullen, Roger Anwyl, Michael S. Wolfe, Michael J. Rowan, Dennis J. Selkoe - Nature 2002 被引用: 4,294
- A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
著者: Bart De Strooper, Wim Annaert, Philippe Cupers, Paul Säftig, Katleen Craessaerts, Jeff S. Mumm, Eric H. Schroeter, Vincent Schrijvers, Michael S. Wolfe, William J. Ray, Alison Goate, Raphael Kopan - Nature 1999 被引用: 2,108
- Presenilins and -Secretase: Structure, Function, and Role in Alzheimer Disease
著者: Bart De Strooper, Takeshi Iwatsubo, Michael S. Wolfe - Cold Spring Harbor Perspectives in Medicine 2011 被引用: 462
- Tumor Necrosis Factor-α, Interleukin-1β, and Interferon-γ Stimulate γ-Secretase-mediated Cleavage of Amyloid Precursor Protein through a JNK-dependent MAPK Pathway
著者: Yung-Feng Liao, Bo‐Jeng Wang, Hui-Ting Cheng, Lan-Hsin Kuo, Michael S. Wolfe - Journal of Biological Chemistry 2004 被引用: 387
- Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
著者: Michael S. Wolfe, Weiming Xia, Beth L. Ostaszewski, Thekla S. Diehl, W. Taylor Kimberly, Dennis J. Selkoe - Nature 1999 被引用: 1,929
- The surface of articular cartilage contains a progenitor cell population
著者: Gary P. Dowthwaite, Joanna Bishop, Samantha Redman, Ilyas M. Khan, Paul Rooney, Darrell J. R. Evans, Laura Haughton, Zubeyde Bayram-Weston, Sam Boyer, B.M. Thomson, Michael S. Wolfe, Charles W. Archer - Journal of Cell Science 2004 被引用: 908
- c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
著者: Andrew P. Weng, John M. Millholland, Yumi Yashiro–Ohtani, Marie-Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G. Rodríguez, Hong Sai, John W. Tobias, Yue‐Ming Li, Michael S. Wolfe, Cathy Shachaf, Dean W. Felsher, Stephen C. Blacklow, Warren S. Pear, Jon C. Aster - Genes & Development 2006 被引用: 885
- Structure and Function of the γ-Secretase Complex
著者: Michael S. Wolfe - Biochemistry 2019 被引用: 119
- The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase
著者: David M. Bolduc, Daniel R. Montagna, Matthew Seghers, Michael S. Wolfe, Dennis J. Selkoe - eLife 2016 被引用: 150
- The Role of Tau in Neurodegenerative Diseases and Its Potential as a Therapeutic Target
著者: Michael S. Wolfe - Scientifica 2012 被引用: 98
- Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease
著者: Lei Liu, Bianca M. Lauro, Amy He, Hyo Lee, Sanjay Bhattarai, Michael S. Wolfe, David A. Bennett, Celeste M. Karch, Tracy L. Young‐Pearse, Dominantly Inherited Alzheimer Network (DIAN), Dennis J. Selkoe - Alzheimer s & Dementia 2022 被引用: 53
- γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2
著者: W. Taylor Kimberly, Matthew J. LaVoie, Beth L. Ostaszewski, Wenjuan Ye, Michael S. Wolfe, Dennis J. Selkoe - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 被引用: 758
- Effects of presenilin-1 familial Alzheimer’s disease mutations on γ-secretase activation for cleavage of amyloid precursor protein
著者: N. Hung, Sujan Devkota, Apurba Bhattarai, Michael S. Wolfe, Yinglong Miao - Communications Biology 2023 被引用: 27
- Familial Alzheimer’s disease mutations in amyloid protein precursor alter proteolysis by γ-secretase to increase amyloid β-peptides of ≥45 residues
著者: Sujan Devkota, Todd D. Williams, Michael S. Wolfe - Journal of Biological Chemistry 2021 被引用: 70
- Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
著者: Sujan Devkota, Rui Zhou, Vaishnavi Nagarajan, Masato Maesako, N. Hung, Arshad Ali Noorani, Caitlin Overmeyer, Sanjay Bhattarai, Justin T. Douglas, Anita Saraf, Yinglong Miao, Brian D. Ackley, Yigong Shi, Michael S. Wolfe - Cell Reports 2024 被引用: 38
- Stabilization of the Tau Exon 10 Stem Loop Alters Pre-mRNA Splicing
著者: Christine P. Donahue, Christina Muratore, Jane Y. Wu, Kenneth S. Kosik, Michael S. Wolfe - Journal of Biological Chemistry 2006 被引用: 107
- A G‐Rich element forms a G‐quadruplex and regulates BACE1 mRNA alternative splicing
著者: Jean‐François Fisette, Daniel R. Montagna, Mihaela‐Rita Mihailescu, Michael S. Wolfe - Journal of Neurochemistry 2012 被引用: 104
- Mechanisms of γ-Secretase Activation and Substrate Processing
著者: Apurba Bhattarai, Sujan Devkota, Sanjay Bhattarai, Michael S. Wolfe, Yinglong Miao - ACS Central Science 2020 被引用: 45
- A Portrait of Alzheimer Secretases-New Features and Familiar Faces
著者: William P. Esler, Michael S. Wolfe - Science 2001 被引用: 494
- Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides
著者: Lei Liu, Bianca M. Lauro, Michael S. Wolfe, Dennis J. Selkoe - Journal of Biological Chemistry 2021 被引用: 45
- Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis
著者: Yoshiharu Miyamoto, Anirban Maitra, Bidyut Ghosh, Ulrich Zechner, Pedram Argani, Christine A. Iacobuzio–Donahue, Virote Sriuranpong, Tatsuya Iso, Ingrid M. Meszoely, Michael S. Wolfe, Ralph H. Hruban, Douglas W. Ball, Roland M. Schmid, Steven D. Leach - Cancer Cell 2003 被引用: 637
- Notch Signaling Augments T Cell Responsiveness by Enhancing CD25 Expression
著者: Scott Adler, Elise Chiffoleau, Lanwei Xu, Nicole M. Dalton, Jennifer M. Burg, Andrew D. Wells, Michael S. Wolfe, Laurence A. Turka, Warren S. Pear - The Journal of Immunology 2003 被引用: 219
- Alzheimer Presenilin-1 Mutations Dramatically Reduce Trimming of Long Amyloid β-Peptides (Aβ) by γ-Secretase to Increase 42-to-40-Residue Aβ
著者: Marty A. Fernandez, Julia A. Klutkowski, Taylor Freret, Michael S. Wolfe - Journal of Biological Chemistry 2014 被引用: 138
- Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)
著者: Suxin Zheng, Yu Chen, Christine P. Donahue, Michael S. Wolfe, Gabriele Varani - Chemistry & Biology 2009 被引用: 96
