Nancy A. Thornberry
1982–2021 年に発表
- 73
- 論文数
- 38,258
- 被引用数
- 73
- h 指数
- 73
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology49.4%
- Medicine31.1%
- Neuroscience6.5%
- Immunology and Microbiology5.7%
- Agricultural and Biological Sciences1.6%
- Chemistry1.4%
- その他4.3%
トピック
- Cell death mechanisms and regulation10.4%
- Mitochondrial Function and Pathology2.7%
- Inflammasome and immune disorders2.4%
- Diabetes Treatment and Management2.3%
- Autophagy in Disease and Therapy2.1%
- Peptidase Inhibition and Analysis1.7%
- その他78.4%
共著者
- Donald W. Nicholson24
- Erin P. Peterson14
- George J. Eiermann11
- Sophie Roy11
- Aleksandr Petrov9
- Ann E. Weber9
- Herbert G. Bull9
- Joseph K. Wu9
- Antony Rosen8
- Barbara Leiting8
- Huaibing He8
- Lan Zhu7
- Livia Casciola‐Rosen7
- Margarita García‐Calvo7
- Ranabir Sinha Roy7
- Reshma A. Patel7
- Bei B. Zhang6
- Dita Rasper6
- John P. Vaillancourt6
- Kathryn A. Lyons6
- Andrew D. Howard5
- Andrew Howard5
- Giovanna Scapin5
- Joseph W. Becker5
全論文
- A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes
著者: Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay, Kevin T. Chapman, Andrew Howard, Matthew J. Kostura, Douglas K. Miller, Susan M. Molineaux, Jeffrey R. Weidner, John Auniņš, Keith Elliston, Julia M. Ayala, Francesca J. Casano, Jayne Chin, G J Ding, Linda A. Egger, Erin P. Gaffney, G Limjuco, Oksana Palyha, S Raju, Anna Rolando, J. Paul Salley, Ting-Ting Yamin, Terry D. Lee, John E. Shively, Malcolm MacCross, Richard A. Mumford, John A. Schmidt, Michael J. Tocci - Nature 1992 被引用: 2,580
- Caspases: Enemies Within
著者: Nancy A. Thornberry, Yuri Lazebnik - Science 1998 被引用: 6,929
- Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy
著者: Robert W. Myers, Hong-Ping Guan, Juliann Ehrhart, Aleksandr Petrov, S. Prahalada, Effie Tozzo, Xiaodong Yang, Marc M. Kurtz, Maria E. Trujillo, Dinko González Trotter, Danqing Feng, Shiyao Xu, George J. Eiermann, Marie A. Holahan, Daniel Rubins, Stacey Conarello, Xiaoda Niu, Sandra C. Souza, Corin O. Miller, Jinqi Liu, Ku Lu, Wen Feng, Ying Li, Ronald E. Painter, James A. Milligan, Huaibing He, Franklin Liu, Aimie M. Ogawa, Douglas Wisniewski, Rory J. Rohm, Liyang Wang, Michelle Bunzel, Ying Qian, Wei Zhu, Hongwu Wang, Bindu Bennet, Lisa LaFranco-Scheuch, Guillermo Bastos Fernández, Cai Li, Michael Klimas, Gaochao Zhou, Margaret van Heek, Tesfaye Biftu, Ann E. Weber, David E. Kelley, Nancy A. Thornberry, Mark D. Erion, Daniel M. Kemp, Iyassu K. Sebhat - Science 2017 被引用: 344
- Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
著者: Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry, John P. Vaillancourt, Connie K. Ding, Michel Gallant, Yves Gareau, Patrick R. Griffin, Marc Labelle, Yuri Lazebnik, Neil A. Munday, Sayyaparaju M. Raju, Mark E. Smulson, Ting-Ting Yamin, Violeta Yu, Douglas K. Miller - Nature 1995 被引用: 4,022
- Glucagon-Like Peptide 1/Glucagon Receptor Dual Agonism Reverses Obesity in Mice
著者: Alessandro Pocai, Paul E. Carrington, Jennifer R. Adams, Michael Wright, George J. Eiermann, Lan Zhu, Xiaobing Du, Aleksandr Petrov, Michael E. Lassman, Guoqiang Jiang, Franklin Liu, Corey Miller, Laurie Tota, Gaochao Zhou, Xiaoping Zhang, Michael M. Sountis, Alessia Santoprete, Elena Capitò, Gary G. Chicchi, Nancy A. Thornberry, Elisabetta Bianchi, Antonello Pessi, Donald J. Marsh, Ranabir SinhaRoy - Diabetes 2009 被引用: 407
- The gut–brain axis: Identifying new therapeutic approaches for type 2 diabetes, obesity, and related disorders
著者: Paul Richards, Nancy A. Thornberry, Shirly Pinto - Molecular Metabolism 2021 被引用: 78
- Human ICE/CED-3 Protease Nomenclature
著者: Emad S. Alnemri, David J. Livingston, Donald W. Nicholson, Guy S. Salvesen, Nancy A. Thornberry, Winnie W. Wong, Junying Yuan - Cell 1996 被引用: 2,383
- A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B
著者: Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson, Dita Rasper, Tracy Timkey, Margarita García‐Calvo, Vicky M. Houtzager, Penny A. Nordstrom, Sophie Roy, John P. Vaillancourt, Kevin T. Chapman, Donald W. Nicholson - Journal of Biological Chemistry 1997 被引用: 2,077
- Optimization of co‐agonism at GLP‐1 and glucagon receptors to safely maximize weight reduction in DIO‐rodents
著者: Jonathan W. Day, Vasily M. Gelfanov, David L. Smiley, Paul E. Carrington, George J. Eiermann, Gary G. Chicchi, Mark D. Erion, Jas Gidda, Nancy A. Thornberry, Matthias H. Tschöp, Donald J. Marsh, Ranabir SinhaRoy, Richard D. DiMarchi, Alessandro Pocai - Biopolymers 2012 被引用: 134
- The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
著者: Margarita García‐Calvo, JeanMarie Lisnock, Herbert G. Bull, Brian E. Hawes, Duane A. Burnett, Matthew P. Braun, James H. Crona, Harry R. Davis, Dennis Dean, Patricia A. Detmers, Michael P. Graziano, Meredith Hughes, D. Euan MacIntyre, Anthony K. Ogawa, Kim A. O’Neill, Sai Prasad N. Iyer, Diane E. Shevell, Marsha M. Smith, Yui S. Tang, Amanda M. Makarewicz, Feroze Ujjainwalla, S. Altmann, Kevin T. Chapman, Nancy A. Thornberry - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 被引用: 768
- Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors
著者: Margarita García‐Calvo, Erin P. Peterson, Barbara Leiting, Réjean Ruel, Donald W. Nicholson, Nancy A. Thornberry - Journal of Biological Chemistry 1998 被引用: 987
- Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4)
著者: Nancy A. Thornberry, Baptist Gallwitz - Best Practice & Research Clinical Endocrinology & Metabolism 2009 被引用: 264
- Caspases: killer proteases
著者: Donald W. Nicholson, Nancy A. Thornberry - Trends in Biochemical Sciences 1997 被引用: 2,423
- Dipeptidyl Peptidase IV Inhibition for the Treatment of Type 2 Diabetes
著者: George R. Lankas, Barbara Leiting, Ranabir Sinha Roy, George J. Eiermann, Maria Beconi, Tesfaye Biftu, Chi‐Chung Chan, Scott D. Edmondson, William P. Feeney, Huaibing He, Dawn E. Ippolito, Dooseop Kim, Kathryn A. Lyons, Hyun Ok, Reshma A. Patel, Aleksandr Petrov, Kelly Ann D. Pryor, Xiaoxia Qian, Leah Reigle, Andrea Woods, Joseph K. Wu, Dennis M. Zaller, Xiaoping Zhang, Lan Zhu, Ann E. Weber, Nancy A. Thornberry - Diabetes 2005 被引用: 491
- Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation
著者: François G. Gervais, Daigen Xu, George S. Robertson, John P. Vaillancourt, Yanxia Zhu, Jingqi Huang, Andréa C. LeBlanc, David W. Smith, Michael Rigby, Mark S. Shearman, Earl E. Clarke, Hui Zheng, Leonardus H.T. Van Der Ploeg, Salvatore C. Ruffolo, Nancy A. Thornberry, Steve Xanthoudakis, Robert Zamboni, Sophie Roy, Donald W. Nicholson - Cell 1999 被引用: 786
- (2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes
著者: Dooseop Kim, Liping Wang, Maria Beconi, George J. Eiermann, Michael H. Fisher, Huaibing He, Gerard J. Hickey, Jennifer E. Kowalchick, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Margaret E. McCann, Reshma A. Patel, Aleksandr Petrov, Giovanna Scapin, Sangita B. Patel, Ranabir Sinha Roy, Joseph K. Wu, Matthew J. Wyvratt, Bei B. Zhang, Lan Zhu, Nancy A. Thornberry, Ann E. Weber - Journal of Medicinal Chemistry 2004 被引用: 817
- Dual Role of Caspase-11 in Mediating Activation of Caspase-1 and Caspase-3 under Pathological Conditions
著者: Shin-Jung Kang, Suyue Wang, Hideaki Hara, Erin P. Peterson, Shobu Namura, Sepideh Amin‐Hanjani, Zhihong Huang, Anu Srinivasan, Kevin J. Tomaselli, Nancy A. Thornberry, Michael A. Moskowitz, Junying Yuan - The Journal of Cell Biology 2000 被引用: 327
- Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance
著者: Stacey Conarello, Zhihua Li, John Ronan, Ranabir Sinha Roy, Lan Zhu, Guoqiang Jiang, Franklin Liu, John Woods, Emanuel Zycband, David E. Moller, Nancy A. Thornberry, Bei B. Zhang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 被引用: 350
- A comparative study of the binding properties, dipeptidyl peptidase‐4 (DPP‐4) inhibitory activity and glucose‐lowering efficacy of the DPP‐4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in mice
著者: Joel P. Berger, Ranabir SinhaRoy, Alessandro Pocai, Theresa M. Kelly, Giovanna Scapin, Ying‐Duo Gao, Kelly Ann D. Pryor, Joseph K. Wu, George J. Eiermann, Shiyao Xu, Xiaoping Zhang, Daniel Tatosian, Ann E. Weber, Nancy A. Thornberry, Richard D. Carr - Endocrinology Diabetes & Metabolism 2017 被引用: 90
- Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
著者: Y. Paul Goldberg, Donald W. Nicholson, Dita Rasper, Michael A. Kalchman, Hiroshi Koide, Rona K. Graham, Michael Bromm, Parsa Kazemi‐Esfarjani, Nancy A. Thornberry, J P Vaillancourt, Michael R. Hayden - Nature Genetics 1996 被引用: 577
- Dipeptidyl Peptidase-4 Inhibitors Administered in Combination With Metformin Result in an Additive Increase in the Plasma Concentration of Active GLP-1
著者: Elizabeth Migoya, Raynald Bergeron, Jutta Miller, Rebekah Snyder, Michael Tanen, D Hilliard, Barry D. Weiss, Patrick Larson, Marie Gutierrez, Guoqiang Jiang, Fang Liu, Kelly Ann D. Pryor, Jun Yao, Lixia Zhu, Jens J. Holst, Carolyn F. Deacon, Gary Herman, Nancy A. Thornberry, John M. Amatruda, Debora Williams‐Herman, John A. Wagner, Ranabir SinhaRoy - Clinical Pharmacology & Therapeutics 2010 被引用: 177
- Chronic Inhibition of Dipeptidyl Peptidase-4 With a Sitagliptin Analog Preserves Pancreatic β-Cell Mass and Function in a Rodent Model of Type 2 Diabetes
著者: James Mu, John Woods, Yun-Ping Zhou, Ranabir Sinha Roy, Zhihua Li, Emanuel Zycband, Yue Feng, Lan Zhu, Cai Li, Andrew D. Howard, David E. Moller, Nancy A. Thornberry, Bei B. Zhang - Diabetes 2006 被引用: 450
- A combinatorial approach for determining protease specificities: application to interleukin-1β converting enzyme (ICE)
著者: Thomas A. Rano, Tracy Timkey, Erin P. Peterson, J. Rotonda, Donald W. Nicholson, Joseph W. Becker, Kevin T. Chapman, Nancy A. Thornberry - Chemistry & Biology 1997 被引用: 258
- Caspases: key mediators of apoptosis
著者: Nancy A. Thornberry - Chemistry & Biology 1998 被引用: 472
