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Ole Isacson

1984–2025 年に発表

145
論文数
28,101
被引用数
101
h 指数
145
i10 指数

被引用数

Ole Isacson の年別被引用数1952 年: 被引用 1 件1985 年: 被引用 5 件1986 年: 被引用 18 件1987 年: 被引用 33 件1988 年: 被引用 54 件1989 年: 被引用 63 件1990 年: 被引用 53 件1991 年: 被引用 63 件1992 年: 被引用 72 件1993 年: 被引用 59 件1994 年: 被引用 53 件1995 年: 被引用 104 件1996 年: 被引用 68 件1997 年: 被引用 66 件1998 年: 被引用 102 件1999 年: 被引用 85 件2000 年: 被引用 122 件2001 年: 被引用 94 件2002 年: 被引用 128 件2003 年: 被引用 209 件2004 年: 被引用 231 件2005 年: 被引用 168 件2006 年: 被引用 239 件2007 年: 被引用 223 件2008 年: 被引用 246 件2009 年: 被引用 354 件2010 年: 被引用 332 件2011 年: 被引用 329 件2012 年: 被引用 273 件2013 年: 被引用 260 件2014 年: 被引用 257 件2015 年: 被引用 244 件2016 年: 被引用 207 件2017 年: 被引用 193 件2018 年: 被引用 214 件2019 年: 被引用 599 件2020 年: 被引用 679 件2021 年: 被引用 622 件2022 年: 被引用 444 件2023 年: 被引用 336 件2024 年: 被引用 433 件2025 年: 被引用 210 件2026 年: 被引用 2 件1953〜1984 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 2,907 件、この内訳の 32.4%イギリス: 引用元論文 728 件、この内訳の 8.1%中国: 引用元論文 582 件、この内訳の 6.5%ドイツ: 引用元論文 476 件、この内訳の 5.3%イタリア: 引用元論文 414 件、この内訳の 4.6%スウェーデン: 引用元論文 357 件、この内訳の 4%カナダ: 引用元論文 341 件、この内訳の 3.8%フランス: 引用元論文 283 件、この内訳の 3.1%日本: 引用元論文 258 件、この内訳の 2.9%スペイン: 引用元論文 229 件、この内訳の 2.5%韓国: 引用元論文 188 件、この内訳の 2.1%オーストラリア: 引用元論文 186 件、この内訳の 2.1%
0%32.4%その他 22.6%

機関

分野

  • Medicine38.7%
  • Biochemistry, Genetics and Molecular Biology31.9%
  • Neuroscience26.2%
  • Engineering0.7%
  • Immunology and Microbiology0.6%
  • Nursing0.4%
  • その他1.5%

トピック

  • Parkinson's Disease Mechanisms and Treatments9.2%
  • Pluripotent Stem Cells Research6.4%
  • Nerve injury and regeneration5.5%
  • Neurogenesis and neuroplasticity mechanisms4.7%
  • Nuclear Receptors and Signaling3.3%
  • CRISPR and Genetic Engineering3.3%
  • その他67.6%

共著者

全論文

検索で開く
  1. α-Synuclein–induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models

    著者: Joseph R. Mazzulli, Friederike Zunke, Ole Isacson, Lorenz Studer, Dimitri Krainc - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 393

  2. Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson’s disease

    著者: Mylene Huebecker, Elizabeth B. Moloney, Aarnoud C. van der Spoel, David A. Priestman, Ole Isacson, Penelope J. Hallett, Frances M. Platt - Molecular Neurodegeneration 2019 被引用: 171

  3. Cell type-specific lipid storage changes in Parkinson’s disease patient brains are recapitulated by experimental glycolipid disturbance

    著者: Oeystein Roed Brekk, Jonathan Roy Honey, Seungil Lee, Penelope J. Hallett, Ole Isacson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 被引用: 106

  4. Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease

    著者: James B. Koprich, Casper Reske-Nielsen, Prabhakar Mithal, Ole Isacson - Journal of Neuroinflammation 2008 被引用: 346

  5. Successful Function of Autologous iPSC-Derived Dopamine Neurons following Transplantation in a Non-Human Primate Model of Parkinson’s Disease

    著者: Penelope J. Hallett, Michela Deleidi, Arnar Astradsson, Gaynor A. Smith, Oliver Cooper, Teresia Osborn, Maria Sundberg, Michele A. Moore, Eduardo Pérez-Torres, Anna‐Liisa Brownell, James M. Schumacher, Roger D. Spealman, Ole Isacson - Cell stem cell 2015 被引用: 335

  6. Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV α-Synucleinopathy

    著者: Chee Yeun Chung, James B. Koprich, Hasan K. Siddiqi, Ole Isacson - Journal of Neuroscience 2009 被引用: 388

  7. Progressive decline of glucocerebrosidase in aging and P arkinson's disease

    著者: Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Eilish Brown, Penelope J. Hallett, Ole Isacson - Annals of Clinical and Translational Neurology 2015 被引用: 214

  8. Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons

    著者: Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Eilish Brown, Melissa A. Hayes, Jonathan A. Beagan, Jesse R. McLean, Sarah C. Izen, Eduardo Pérez-Torres, Penelope J. Hallett, Ole Isacson - Neurobiology of Disease 2015 被引用: 162

  9. Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

    著者: Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Anne-Renee Graham, Eilish Brown, Jesse R. McLean, Melissa A. Hayes, Jonathan A. Beagan, Sarah C. Izen, Eduardo Pérez-Torres, Penelope J. Hallett, Ole Isacson - Antioxidants and Redox Signaling 2015 被引用: 153

  10. Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease

    著者: Oliver Cooper, Hyemyung Seo, Shaida A. Andrabi, Cristina Guardia‐Laguarta, John J. Graziotto, Maria Sundberg, Jesse R. McLean, Luis Carrillo‐Reid, Zhong Xie, Teresia Osborn, Gunnar Hargus, Michela Deleidi, Tristan Lawson, Helle Bogetofte, Eduardo Pérez-Torres, Lorraine N. Clark, Carol Moskowitz, Joseph R. Mazzulli, Li Chen, Laura A. Volpicelli‐Daley, Norma B. Romero, Houbo Jiang, Ryan J. Uitti, Zhigao Huang, Grzegorz Opala, Leslie A. Scarffe, Valina L. Dawson, Christine Klein, Jian Feng, Owen A. Ross, John Q. Trojanowski, Virginia M.‐Y. Lee, Karen Marder, D. James Surmeier, Zbigniew K. Wszołek, Serge Przedborski, Dimitri Krainc, Ted M. Dawson, Ole Isacson - Science Translational Medicine 2012 被引用: 506

  11. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

    著者: Frank Soldner, Dirk Hockemeyer, Caroline Beard, Qing Gao, George W. Bell, Elizabeth Cook, Gunnar Hargus, Alexandra Blak, Oliver Cooper, Maisam Mitalipova, Ole Isacson, Rudolf Jaenisch - Cell 2009 被引用: 1,544

  12. LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction

    著者: Laurie H. Sanders, Josée Laganière, Oliver Cooper, Sally K. Mak, B. Joseph Vu, Ying Huang, David E. Paschon, Malini Vangipuram, Ramya Sundararajan, Fyodor D. Urnov, J. William Langston, Philip D. Gregory, H. Steve Zhang, J. Timothy Greenamyre, Ole Isacson, Birgitt Schüle - Neurobiology of Disease 2013 被引用: 277

  13. The glycoprotein GPNMB is selectively elevated in the substantia nigra of Parkinson's disease patients and increases after lysosomal stress

    著者: Elizabeth B. Moloney, Alyssa Moskites, Eliza J. Ferrari, Ole Isacson, Penelope J. Hallett - Neurobiology of Disease 2018 被引用: 126

  14. Integrated molecular landscape of Parkinson’s disease

    著者: Cornelius J. H. M. Klemann, Gerard J.M. Martens, Manu Sharma, Marijn Bart Martens, Ole Isacson, Thomas Gasser, Jasper E. Visser, Geert Poelmans - npj Parkinson s Disease 2017 被引用: 126

  15. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

    著者: Marius Wernig, Jian-Ping Zhao, Jan Pruszak, Eva Hedlund, Dongdong Fu, Frank Soldner, Vania Broccoli, Martha Constantine‐Paton, Ole Isacson, Rudolf Jaenisch - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 被引用: 1,212

  16. The Threshold Theory for Parkinson's Disease

    著者: Simone Engelender, Ole Isacson - Trends in Neurosciences 2016 被引用: 191

  17. Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics

    著者: Ling Lin, Timothy G. Lesnick, Demetrius M. Maraganore, Ole Isacson - Trends in Neurosciences 2009 被引用: 167

  18. Altered Proteasomal Function in Sporadic Parkinson's Disease

    著者: Kevin St. P. McNaught, Roger Belizaire, Ole Isacson, Peter Jenner, C. Warren Olanow - Experimental Neurology 2002 被引用: 572

  19. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years

    著者: Ivar Mendez, Ángel Viñuela, Arnar Astradsson, Karim Mukhida, Penelope J. Hallett, H.A. Robertson, Travis Tierney, Renn O. Holness, Alain Dagher, John Q. Trojanowski, Ole Isacson - Nature Medicine 2008 被引用: 434

  20. Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection

    著者: Chee Yeun Chung, Hyemyung Seo, Kai‐Christian Sonntag, Andrew I. Brooks, Ling Lin, Ole Isacson - Human Molecular Genetics 2005 被引用: 371

  21. Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson’s disease

    著者: Penelope J. Hallett, Simone Engelender, Ole Isacson - Journal of Neuroinflammation 2019 被引用: 109

  22. Widespread neuron-specific transgene expression in brain and spinal cord following synapsin promoter-driven AAV9 neonatal intracerebroventricular injection

    著者: Jesse R. McLean, Gaynor A. Smith, Emily M. Rocha, Melissa A. Hayes, Jonathan A. Beagan, Penelope J. Hallett, Ole Isacson - Neuroscience Letters 2014 被引用: 109

  23. Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson’s disease patient fibroblasts

    著者: Joanna A. Korecka, Ria Thomas, Dan Ploug Christensen, Anthony J. Hinrich, Eliza J. Ferrari, Simon A. Levy, Michelle L. Hastings, Penelope J. Hallett, Ole Isacson - Human Molecular Genetics 2019 被引用: 66

  24. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

    著者: Gunnar Hargus, Oliver Cooper, Michela Deleidi, Adam Levy, Kristen Lee, Elizabeth Marlow, Alyssa Yow, Frank Soldner, Dirk Hockemeyer, Penelope J. Hallett, Teresia Osborn, Rudolf Jaenisch, Ole Isacson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 被引用: 473