Reinhard Lührmann
1982–2025 年に発表
- 179
- 論文数
- 37,624
- 被引用数
- 113
- h 指数
- 178
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology82%
- Medicine9.2%
- Agricultural and Biological Sciences2.7%
- Immunology and Microbiology2.7%
- Chemistry1%
- Neuroscience0.8%
- その他1.6%
トピック
- RNA Research and Splicing19.7%
- RNA modifications and cancer13.7%
- RNA and protein synthesis mechanisms12%
- Nuclear Structure and Function3%
- RNA Interference and Gene Delivery2.6%
- RNA regulation and disease2.4%
- その他46.6%
共著者
- Cindy L. Will55
- Henning Urlaub50
- Berthold Kastner30
- Holger Stark26
- Patrizia Fabrizio22
- Olexandr Dybkov18
- Klaus Hartmuth16
- Dmitry E. Agafonov13
- M.C. Wahl12
- Tilmann Achsel12
- Evgeny M. Makarov10
- Ralf Ficner9
- Utz Fischer9
- Vladimir Peña8
- Bjoern Sander7
- Matthias Wilm7
- Monika M. Golas7
- Peter Bringmann7
- Sergey Bessonov7
- Sina Mozaffari‐Jovin7
- Cyrille Girard6
- Hero Brahms6
- Jana Schmitzová6
- Olga V. Makarova6
全論文
- Spliceosome Structure and Function
著者: C. L. Will, Reinhard Lührmann - Cold Spring Harbor Perspectives in Biology 2010 被引用: 1,836
- The Spliceosome: Design Principles of a Dynamic RNP Machine
著者: M.C. Wahl, Cindy L. Will, Reinhard Lührmann - Cell 2009 被引用: 2,704
- GraFix: sample preparation for single-particle electron cryomicroscopy
著者: Berthold Kastner, N. Fischer, Monika M. Golas, Bjoern Sander, Prakash Dube, Daniel Boehringer, Klaus Hartmuth, Jochen Deckert, Florian Hauer, Elmar Wolf, Hannes Uchtenhagen, Henning Urlaub, Franz Herzog, Jan Peters, Dietmar Poerschke, Reinhard Lührmann, Holger Stark - Nature Methods 2007 被引用: 604
- Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes
著者: Berthold Kastner, Cindy L. Will, Holger Stark, Reinhard Lührmann - Cold Spring Harbor Perspectives in Biology 2019 被引用: 250
- Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion
著者: Cyrille Girard, Cindy L. Will, Jianhe Peng, Evgeny M. Makarov, Berthold Kastner, Ira Lemm, Henning Urlaub, Klaus Hartmuth, Reinhard Lührmann - Nature Communications 2012 被引用: 296
- Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds
著者: Constantin Cretu, Anant A. Agrawal, Andrew S. Cook, Cindy L. Will, Peter Fekkes, Peter G. Smith, Reinhard Lührmann, Nicholas Larsen, Silvia Buonamici, Vladimir Peña - Molecular Cell 2018 被引用: 176
- Molecular architecture of the human 17S U2 snRNP
著者: Zhenwei Zhang, Cindy L. Will, Karl Bertram, Olexandr Dybkov, Klaus Hartmuth, Dmitry E. Agafonov, Romina Hofele, Henning Urlaub, Berthold Kastner, Reinhard Lührmann, Holger Stark - Nature 2020 被引用: 112
- Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations
著者: Constantin Cretu, Jana Schmitzová, Almudena Ponce-Salvatierra, Olexandr Dybkov, Evelina Ines De Laurentiis, Kundan Sharma, Cindy L. Will, Henning Urlaub, Reinhard Lührmann, Vladimir Peña - Molecular Cell 2016 被引用: 252
- Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
著者: Adriana Buskin, Lili Zhu, Valeria Chichagova, Basudha Basu, Sina Mozaffari‐Jovin, David Dolan, Alastair Droop, Joseph Collin, Revital Bronstein, Sudeep Mehrotra, Michael H. Farkas, Gerrit Hilgen, Kathryn White, Kuan‐Ting Pan, Achim Treumann, Dean Hallam, Katarzyna Bialas, Git Chung, Carla Mellough, Yuchun Ding, Natalio Krasnogor, Stefan Przyborski, Simon Zwolinski, Jumana Y. Al‐Aama, Sameer Alharthi, Yaobo Xu, Gabrielle Wheway, Katarzyna Szymańska, Martin McKibbin, Chris F. Inglehearn, David J. Elliott, Susan Lindsay, Robin R. Ali, David Steel, Lyle Armstrong, Evelyne Sernagor, Henning Urlaub, Eric A. Pierce, Reinhard Lührmann, Sushma-Nagaraja Grellscheid, Colin A. Johnson, Majlinda Lako - Nature Communications 2018 被引用: 238
- Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome
著者: Anna Hegele, Atanas Kamburov, Arndt Großmann, Chrysovalantis Sourlis, Sylvia J. Wowro, Mareike Weimann, Cindy L. Will, Vlad Peña, Reinhard Lührmann, Ulrich Stelzl - Molecular Cell 2012 被引用: 431
- Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi
著者: Javier Martı̂nez, Agnieszka Patkaniowska, Henning Urlaub, Reinhard Lührmann, Thomas Tuschl - Cell 2002 被引用: 1,448
- HSPC117 Is the Essential Subunit of a Human tRNA Splicing Ligase Complex
著者: Johannes Popow, Markus Englert, Stefan Weitzer, Alexander Schleiffer, Beata E. Mierzwa, Karl Mechtler, Simon Trowitzsch, Cindy L. Will, Reinhard Lührmann, Dieter Söll, Javier Martı̂nez - Science 2011 被引用: 258
- Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex
著者: David Haselbach, Ilya Komarov, Dmitry E. Agafonov, Klaus Hartmuth, Benjamin Graf, Olexandr Dybkov, Henning Urlaub, Berthold Kastner, Reinhard Lührmann, Holger Stark - Cell 2018 被引用: 227
- Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation
著者: C. Townsend, Majety Naga Leelaram, Dmitry E. Agafonov, Olexandr Dybkov, Cindy L. Will, Karl Bertram, Henning Urlaub, Berthold Kastner, Holger Stark, Reinhard Lührmann - Science 2020 被引用: 91
- Structural insights into how Prp5 proofreads the pre-mRNA branch site
著者: Zhenwei Zhang, Norbert Rigo, Olexandr Dybkov, Jean‐Baptiste Fourmann, Cindy L. Will, Vinay Kumar, Henning Urlaub, Holger Stark, Reinhard Lührmann - Nature 2021 被引用: 65
- Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation
著者: Karl Bertram, Dmitry E. Agafonov, Olexandr Dybkov, David Haselbach, Majety Naga Leelaram, Cindy L. Will, Henning Urlaub, Berthold Kastner, Reinhard Lührmann, Holger Stark - Cell 2017 被引用: 297
- Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein
著者: Cindy L. Will, Henning Urlaub, Tilmann Achsel, Marc Gentzel, Matthias Wilm, Reinhard Lührmann - The EMBO Journal 2002 被引用: 308
- Molecular architecture of the human U4/U6.U5 tri-snRNP
著者: Dmitry E. Agafonov, Berthold Kastner, Olexandr Dybkov, Romina Hofele, Wen-Ti Liu, Henning Urlaub, Reinhard Lührmann, Holger Stark - Science 2016 被引用: 199
- A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity
著者: Carsten Boesler, Norbert Rigo, Maria Anokhina, M.J. Tauchert, Dmitry E. Agafonov, Berthold Kastner, Henning Urlaub, Ralf Ficner, Cindy L. Will, Reinhard Lührmann - Nature Communications 2016 被引用: 82
- Spliceosomal UsnRNP biogenesis, structure and function
著者: Cindy L. Will, Reinhard Lührmann - Current Opinion in Cell Biology 2001 被引用: 687
- Semiquantitative Proteomic Analysis of the Human Spliceosome via a Novel Two-Dimensional Gel Electrophoresis Method
著者: Dmitry E. Agafonov, Jochen Deckert, Elmar Wolf, Peter Odenwälder, Sergey Bessonov, Cindy L. Will, Henning Urlaub, Reinhard Lührmann - Molecular and Cellular Biology 2011 被引用: 232
- Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
著者: Reinhard Rauhut, Patrizia Fabrizio, Olexandr Dybkov, Klaus Hartmuth, Vladimir Peña, Ashwin Chari, Vinay Kumar, Chung‐Tien Lee, Henning Urlaub, Berthold Kastner, Holger Stark, Reinhard Lührmann - Science 2016 被引用: 186
- Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
著者: Giacomo Cossa, Isabelle Roeschert, Florian Prinz, Apoorva Baluapuri, Raphael Vidal, Christina Schülein‐Völk, Yun-Chien Chang, Carsten P. Ade, Guido Mastrobuoni, Cyrille Girard, Amit Kumar, Lars Wortmann, Susanne Walz, Reinhard Lührmann, Stefan Kempa, Bernhard Küster, Elmar Wolf, Dominik Mumberg, Martin Eilers - Molecular Cell 2020 被引用: 64
- Structural insights into the cross-exon to cross-intron spliceosome switch
著者: Zhenwei Zhang, Vinay Kumar, Olexandr Dybkov, Cindy L. Will, Jiayun Zhong, Sebastian Ludwig, Henning Urlaub, Berthold Kastner, Holger Stark, Reinhard Lührmann - Nature 2024 被引用: 36
